Basic Information

Insect: Eugnorisma glareosa
Gene Symbol: CTCF
Assembly: GCA_947578425.1
Location: OX387957.1:46001338-46018183[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0019 0.16 13.1 5.9 1 23 186 208 186 208 0.98

2 11 1.8e-05 0.0016 19.4 1.3 1 23 214 236 214 236 0.98

3 11 7e-05 0.0061 17.6 1.7 1 23 242 265 242 265 0.96

4 11 0.033 2.9 9.2 3.2 1 21 271 291 271 293 0.95

5 11 0.0001 0.0091 17.0 2.7 1 23 299 321 299 321 0.99

6 11 1.4e-05 0.0012 19.7 5.3 1 23 327 349 327 349 0.98

7 11 0.0032 0.28 12.3 0.9 1 23 357 380 357 380 0.97

8 11 0.017 1.5 10.0 4.3 2 23 387 408 386 408 0.96

9 11 4.6e-05 0.004 18.1 2.9 1 23 414 436 414 436 0.98

10 11 4.3e-06 0.00037 21.4 1.7 1 23 442 465 442 465 0.95

11 11 3e-05 0.0026 18.7 6.0 1 23 479 501 479 501 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0019	0.16	13.1	5.9	1	23	186	208	186	208	0.98
2	11	1.8e-05	0.0016	19.4	1.3	1	23	214	236	214	236	0.98
3	11	7e-05	0.0061	17.6	1.7	1	23	242	265	242	265	0.96
4	11	0.033	2.9	9.2	3.2	1	21	271	291	271	293	0.95
5	11	0.0001	0.0091	17.0	2.7	1	23	299	321	299	321	0.99
6	11	1.4e-05	0.0012	19.7	5.3	1	23	327	349	327	349	0.98
7	11	0.0032	0.28	12.3	0.9	1	23	357	380	357	380	0.97
8	11	0.017	1.5	10.0	4.3	2	23	387	408	386	408	0.96
9	11	4.6e-05	0.004	18.1	2.9	1	23	414	436	414	436	0.98
10	11	4.3e-06	0.00037	21.4	1.7	1	23	442	465	442	465	0.95
11	11	3e-05	0.0026	18.7	6.0	1	23	479	501	479	501	0.97

Sequence Information

Coding Sequence: ATGCCACCTCCAATTAAAAAGGAGAAAAACAAGCAAGCGCTCATTCAAACATACTTGAACCAAGGAGcagtcatcacagTCAACGCAGCTTCAGATGATAAAAGCTTGCCTACTGGAATGGTCGAGTATTTCGTAGATGAAGATGGCAAGTACTACTACCAGTCATCTGTTGGAGGGCAGACCCTGGTCATGAATACGGAAGCCACCCAAGAAAATGAGGAGCCTACTGATACCCCGGACCCGATTATGACTGAGCAAGGGGAAACGTACCAGACGGTCGCCTTCCTCCCCACGGAGAACAATGGGGAAGTGAGCTATGTCCTTGTAGTGCAAGAAGAGAACAAGGGTGGTGTAGTCAACATGGAACTCAAGGTGGACGAGGGACGGGAGAATGTGAAGACCGAGGCTGAGGAGAAAGCCAACGATGACGTGTACAACTTTGACGATGAGGAGGCCGGCGAAGACGAGGAAGAGGAAGAAGGGGACGCGGAAATGGCCGACGGCACTAAACCCAAGCCTTCGAACAAGACGCGCTCCAAGCACGTGCGCCCACACTTCACCTGCAACTTCTGCAACTATACTAGTCATCGCCGATACCTCCTCCTACGACACATGAAGTCCCACTCGGAGGACAGGCCGCACAAGTGCAACGTGTGCGAGCGCGGCTTCAAGACGCTGGCGTCGCTTCAGAACCACGTGAACATGCACAACGGCGTCAAGCCGCACGTCTGCAAGTACTGCAACAGCCCCTTTACTACCTCGGGCGAGCTGGTGCGTCACGTACGCTACAAGCACACGCACGAGAAGCCGCACAAGTGCTCGGAGTGCGACTACGCGTCCGTGGAGCTGTCCAAGCTGCGCCGCCACGTGCGCTGCCACACCGGCGAGAGGCCCTACCAGTGCCCGCACTGCACGTACGCGTCGCCGGACACGTTCAAGCTGAAACGCCACCTGCGCACGCACACCGGCGAGAAGCCCTACAAGTGCGAGCACTGCAACATGTGTTTCACGCAGTCCAACTCGCTGAAAGCCCACCGGCTCATTCACAATGTATCCGAGAAGCCGGTATACTCATGCGAGCTGTGCCCGGCCAAGTGCGGCCGCAAGACGGACCTGCGCATCCACGTGCAGAAGCTGCACACGTCCGACAAGCCACTGAAGTGCCGCCGCTGTGGCAAGTCGTTCCCCGACCGCTACTCCTGCAAGGTGCACAATAAGACCCACGAGGGCGAGAAATGCTTCAAGTGCGACCTGTGCCCGTACGCGTCGACCACGCAGCGCCATCTCAAGACGCACATGCTCAAGCACACGGACGAGAAGCCGTTCATCTGCGACATGTGCGACCAGTCCTTCAGGCAAAAGCAGTTGCTCCGTCGCCACCAGAACCTGTACCACAATCCCAACTACGTGCCGAAGCCGCCCAAGGAGAAGACGCACTCCTGCCATGAGTGCCACCGCATGTTCGCGCACAAGGGCAACCTCATCCGGCACCTGGCCGTGCACGACCCCGAGTCCGGCCATCACGAGCGCGCTCTCGCCCTCAAGATTGGACGCCAGAGGAAGGTTCGGTTCGTCGATGGCGAACCTATGAGGGATATCCGCGTCCTGGACCCATCGGACACCGAGAGCATGATGAAGCTCGGTCTCACCAACAACGGGTTGAAGCACGGCGAGCTCGTGACTGTGGCCGACGATGACGGCCACCAGTATGTGGTGCTCGAGGTCATTCAACTCGAGGACGGCACCGAGCAGCAGGTGGCCGTCGTGGCACCCGAATTCATGGATGAGGATGAGCCTGAAGAGGAAGAGGAAGAGGAGGAAGAGGACGAAGAAGATGAAGACGAGGAAGAAGAAGAGGGAAAAGACAGGAGCTTTGTTGTAAAGGAAAGCACTGTCACCACCACAAGCATTAAACTTGAGAAGGAGGTTGACACGTGCTTTGGATTTGATGAGGAAGACGAAGAAGAAGAAGAAGAAAACGATGAAATTGATGTCGATGTTAACTATACAGATAAAGTGGTTCTGCATTTAGTTTAG
Protein Sequence: MPPPIKKEKNKQALIQTYLNQGAVITVNAASDDKSLPTGMVEYFVDEDGKYYYQSSVGGQTLVMNTEATQENEEPTDTPDPIMTEQGETYQTVAFLPTENNGEVSYVLVVQEENKGGVVNMELKVDEGRENVKTEAEEKANDDVYNFDDEEAGEDEEEEEGDAEMADGTKPKPSNKTRSKHVRPHFTCNFCNYTSHRRYLLLRHMKSHSEDRPHKCNVCERGFKTLASLQNHVNMHNGVKPHVCKYCNSPFTTSGELVRHVRYKHTHEKPHKCSECDYASVELSKLRRHVRCHTGERPYQCPHCTYASPDTFKLKRHLRTHTGEKPYKCEHCNMCFTQSNSLKAHRLIHNVSEKPVYSCELCPAKCGRKTDLRIHVQKLHTSDKPLKCRRCGKSFPDRYSCKVHNKTHEGEKCFKCDLCPYASTTQRHLKTHMLKHTDEKPFICDMCDQSFRQKQLLRRHQNLYHNPNYVPKPPKEKTHSCHECHRMFAHKGNLIRHLAVHDPESGHHERALALKIGRQRKVRFVDGEPMRDIRVLDPSDTESMMKLGLTNNGLKHGELVTVADDDGHQYVVLEVIQLEDGTEQQVAVVAPEFMDEDEPEEEEEEEEEDEEDEDEEEEEGKDRSFVVKESTVTTTSIKLEKEVDTCFGFDEEDEEEEEENDEIDVDVNYTDKVVLHLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00301464;
90% Identity: iTF_01062117;
80% Identity: -