Basic Information

Insect: Euglossa dilemma
Gene Symbol: br_2
Assembly: GCA_002201625.1
Location: NIJG01000136.1:412414-420955[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.7e-29 9.6e-27 93.1 0.0 1 100 22 117 22 124 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.7e-29	9.6e-27	93.1	0.0	1	100	22	117	22	124	0.95

Sequence Information

Coding Sequence: ATGGGTTCGAGTCAACAATTTTCTCTTAGGTGGAATAACTACTTGAAACATATTACTTGTGCTTTTGACACATTAAGAACAGAGGAAGATCTTGTTGATGTAACTTTAAGTTGCGAGGGAAAAAGAATAAGAGCACACAAAATGCTTTTATCCGCGTGTAGTACATATTTTAGAGATTTATTTAAGGAAAATCCATGTCAGCATCCTGTCATAATATTTCGTAATGTAAAATTTGATGATTTGGCTGCGTTAGTTGATTTTATGTATCAAGGTGAAGTAAATGTAGTACAGGAACAATTAGCCAGTTTTTTAACAACTGCTGAACTACTCGCTGTTCAGGGTCTTACAGATGGTACAGGGAAAGATAACGATAGTTTAGTAGAGGATGACATAGAAATTCCAAATGAACCTGAAATTCAACTTCAAAATGCTTCTAGTAAAACAACAACAGACAAAAGAAATAAATCACCTTCATCTCCAATGCCTTACCATGCTGTTGATTTACAACCAGATGCCCCACCGAGTAAAAGACGAAAATGTAGAGAAAATGCAAATACAAATGCAGATAAGGCTATAAGTAATGCTTTATCTGGAAAAGATTCTGATAATAAGACTTCAGAAAATCAATCAACAACTGGCTCGGATCCTGTTGAAATAATTCCTCTAATGCCGAATTTAAAGTTGGAAATGCCTGAATATCTAGTACAAGATGGAAGTAGCTGTAGTTACGAAGAACAAAGTTTAGGAGACAGTTCGCTAAACAAAATTGGTATAGAAGATACATCATCTAATACTCCTGATCATGATCAGAAGCCTGATATTACTCAAACATTTTATTCAAGTAATCAGTCTACTTCAGATAGTTTGGATCTTAAACATCAAACAGCCGATGTTGGACACTTGCTTTCAAAACCTAGTACTTCTGGAGAAAGGTTAACGCAAGAAGCAGTACAGGAACGAGCAGGAGATACCGCAGGGGGCGGGGGTGGTAGCGCCGGTCCTGCAACCGCGGACCTCGTCTCGGACGATGACTACGGTCAGTCCACGGATACTGAATTATTGTTTCGCTGTAGAATTTGTTGGAAAGGTTTCAAGCATCCGATGTCGTTGACACTGCACAAGGACTTGCATACAGGGCAAACCAGGTGCCCGATTTGTCAGCGCATTTTCAGTCGAAGTTACGACATGAAGGCTCATTTGCTGCGCATCCACAAGTGCACGTTCAGTGTCGACGCAAAGTTGAACTTTCGAAAG
Protein Sequence: MGSSQQFSLRWNNYLKHITCAFDTLRTEEDLVDVTLSCEGKRIRAHKMLLSACSTYFRDLFKENPCQHPVIIFRNVKFDDLAALVDFMYQGEVNVVQEQLASFLTTAELLAVQGLTDGTGKDNDSLVEDDIEIPNEPEIQLQNASSKTTTDKRNKSPSSPMPYHAVDLQPDAPPSKRRKCRENANTNADKAISNALSGKDSDNKTSENQSTTGSDPVEIIPLMPNLKLEMPEYLVQDGSSCSYEEQSLGDSSLNKIGIEDTSSNTPDHDQKPDITQTFYSSNQSTSDSLDLKHQTADVGHLLSKPSTSGERLTQEAVQERAGDTAGGGGGSAGPATADLVSDDDYGQSTDTELLFRCRICWKGFKHPMSLTLHKDLHTGQTRCPICQRIFSRSYDMKAHLLRIHKCTFSVDAKLNFRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00216477;
90% Identity: iTF_00685072; iTF_00215105; iTF_00217828; iTF_00215336; iTF_00219432; iTF_00219881; iTF_00225321; iTF_00233546; iTF_00222827; iTF_00225998; iTF_00225553; iTF_00220117; iTF_00226233; iTF_00229433; iTF_00218044; iTF_00219199; iTF_00233311; iTF_00229664; iTF_00962593; iTF_01122727; iTF_01123143; iTF_00963277; iTF_00962831; iTF_00964560; iTF_00963505; iTF_00961912; iTF_00962138; iTF_00964762; iTF_01123322; iTF_00982369; iTF_00224195; iTF_00982597; iTF_00224876; iTF_00218743; iTF_00224632; iTF_01070689; iTF_01066341; iTF_01070443; iTF_01065651; iTF_01066581; iTF_01065880; iTF_01539937; iTF_01419075; iTF_01419718; iTF_01421009; iTF_01421204; iTF_01419295; iTF_01419936; iTF_00228293; iTF_00231400; iTF_00228053; iTF_00231639; iTF_01418022; iTF_01454504; iTF_01454275; iTF_00141481; iTF_00140908; iTF_00141292; iTF_00140672; iTF_00084650; iTF_00085809; iTF_00084928; iTF_01256042; iTF_01255784; iTF_00983275; iTF_00983046; iTF_01424686; iTF_01424457; iTF_00763314; iTF_00763528; iTF_00393684; iTF_00393931; iTF_00676341; iTF_00676106; iTF_00184248; iTF_00184021; iTF_01169497; iTF_01169258; iTF_00862906; iTF_00862662; iTF_00223515; iTF_00223275; iTF_00118333; iTF_00118090; iTF_00228991; iTF_00228754; iTF_00360544; iTF_00360298;
80% Identity: iTF_00685072;