Emex001359.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eufriesea mexicana
Gene Symbol
fru
Assembly
GCA_001483705.1
Location
NW:1455304-1463547[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.7e-24 4.2e-22 77.6 0.0 1 98 42 135 42 142 0.94

Sequence Information

Coding Sequence
ATGGGAGATTATAAATGTATAACTTTACAAGATATATATGAGAACACTGGACACGTTACAATAATGGGTGAAAAAACATTTAACCTCACCTGGAATAATCACCTAGCAAACTTGTCTGGATTGTTTGAAGGATTATATAAGAGTGGTTCCTTGACTGATACTACGTTAGCTTGTCAAGGTGGCATGCTGAGGGCGCACAGATTAGTCTTGGCAGCATGTAGTCCTTACTTTGAAAGAGTCTTCAAAGAACACTATGGTGAACAGCCAATTCTTATTTTAAAAGGTGTCGCGGTCGAAGAAATGGAATGTCTCCTCGACTTCATGTATCGAGGTTCGATCGACGTCGCCGAGGAACACTTGCCATCTCTGATTAAAACTGCGACAGATCTAGAGATTCGTGGTCTTTCCGGCGACCAGAGGAATCAAGACAACAATCGTAGCCCCTACACTAGGGTAGAGACACGAATGCAACGATGTCACATAGAAGCCAGAGTTCACACGACGGAGTACATGAAGGAACCGTCCGCGATTCCATTCTTACCAAAACAGTCTTCCGTAGAGTCATTAGAGGATCATATAAAAGTGGAGGAGATCGAGGTGGAAGATGACCCCATGGTGATCGATGGCCATGAGGACGCGTTCGATGAGCCCTTGCGATCGCCGGAAACGCAAATCAGACGTATGCCACCACCGATGTACAAACGAGAAACGAGATTCAAAGGTCAGAAAAGAGTCTCCGTAGGACGTTCAACAAGAAATAGCGATATACTGGAATTCAGATCGAAGGAACGCTTAGTTTCGAAAGAAGATTCTTCGAGGGAGAGTTACGAGGATTCAAACGCGTTTAAATCCGAgccgaattttaataattcatctGCAGATCCCACGGTACCGGATATACAGATGAACGACGACTTACAAGAACGAGATGAAAGTCTGGATTCTTCAAAGAGCTCAGATGATAACCCAAGATTGACCATCAAGAAGAAGGGCGACATCTCTACAAAGAGATCAGGACTAAATGAAGGTAAAGAGACCAGGCCGATACAGGCGAAGTCTGAAAAGGCGCAATACAAACCTTTCTCCTGCGACCTTTGTACTTTAGCTTTTACACGAGCTTCTCACTTGGCTAGACATAGAAGAGTTCACACGGGCGAACGACCATTTGCCTGTAACATTTGTCCTCGAATGTTTGCTAGACAGGATAAACTGAAGCAGCATGTGGACTCGCATTTACAGTGGCCGAAAAGAAAGAATAGCTTGTCGAGTTCGAGTTGTCAGTCAGCACCCTCTGTACCTGGCAAAGGAAAACGAGGTAGACCGAGAAAGGTAAATTTAGAACAGTCAGCCAtggaagaaattttgaaattcggTGAATTCAGTTCTCTCCTGAACAAATCCCATTCCGCGAATTCAACAGACAAAAACGAGGATTTTACTTCTAACGAGGATGACAGAAAAATGAAGGAACAAGAGGAAGACATGGTAGAAGAGGAAAAtgaagataaagataaagaCGCGAATAAAGATAAAGACAATTACGGTTGTCAGGTCGAAAATGGTcaagatattatttaa
Protein Sequence
MGDYKCITLQDIYENTGHVTIMGEKTFNLTWNNHLANLSGLFEGLYKSGSLTDTTLACQGGMLRAHRLVLAACSPYFERVFKEHYGEQPILILKGVAVEEMECLLDFMYRGSIDVAEEHLPSLIKTATDLEIRGLSGDQRNQDNNRSPYTRVETRMQRCHIEARVHTTEYMKEPSAIPFLPKQSSVESLEDHIKVEEIEVEDDPMVIDGHEDAFDEPLRSPETQIRRMPPPMYKRETRFKGQKRVSVGRSTRNSDILEFRSKERLVSKEDSSRESYEDSNAFKSEPNFNNSSADPTVPDIQMNDDLQERDESLDSSKSSDDNPRLTIKKKGDISTKRSGLNEGKETRPIQAKSEKAQYKPFSCDLCTLAFTRASHLARHRRVHTGERPFACNICPRMFARQDKLKQHVDSHLQWPKRKNSLSSSSCQSAPSVPGKGKRGRPRKVNLEQSAMEEILKFGEFSSLLNKSHSANSTDKNEDFTSNEDDRKMKEQEEDMVEEENEDKDKDANKDKDNYGCQVENGQDII

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00684424; iTF_00684873; iTF_00685040; iTF_01069250; iTF_01068580; iTF_01065673; iTF_01068395; iTF_01067213; iTF_01069073; iTF_01066549; iTF_01067893; iTF_01065848; iTF_01066360; iTF_01070651; iTF_01070462; iTF_01067039; iTF_01067711; iTF_01069769; iTF_01069957; iTF_00625772; iTF_00625603; iTF_00232081; iTF_00229634; iTF_00228068; iTF_00227557; iTF_00226695; iTF_00229447; iTF_00219400; iTF_00224650; iTF_00233514; iTF_00215307; iTF_00222795; iTF_00227372; iTF_00224845; iTF_00230317; iTF_00219215; iTF_00233327; iTF_00230129; iTF_00225522; iTF_00232242; iTF_00214643; iTF_00215124; iTF_00217844; iTF_00220084; iTF_00231606; iTF_00218711; iTF_00231415; iTF_00214488; iTF_00225336; iTF_00232696; iTF_00232856; iTF_00215993; iTF_00219897; iTF_00223481; iTF_00218010; iTF_00223292; iTF_00226204; iTF_00230940; iTF_00215805; iTF_00218525; iTF_00226014; iTF_00222623; iTF_00226879; iTF_00230783; iTF_00228256; iTF_00761241; iTF_00761101; iTF_00676122; iTF_00676290; iTF_01424476; iTF_01424647; iTF_00220868; iTF_00220684; iTF_00217175; iTF_00217372; iTF_00361005; iTF_00361202; iTF_00360503; iTF_00360314; iTF_01122706; iTF_01123303; iTF_01122550; iTF_01123158; iTF_01418627; iTF_01419265; iTF_01420548; iTF_01420358; iTF_01418441; iTF_01419090; iTF_01419731; iTF_01421180; iTF_01419901; iTF_01421022; iTF_00087300; iTF_00084869; iTF_00086696; iTF_00085513; iTF_00088938; iTF_00088146; iTF_00086421; iTF_00088373; iTF_00084666; iTF_00085757; iTF_00087519; iTF_00089152; iTF_00228773; iTF_00228960; iTF_00961925; iTF_00962102; iTF_00964732; iTF_00964574; iTF_00303206; iTF_00303395; iTF_00223977; iTF_00224166; iTF_00964106; iTF_00963938; iTF_00306380; iTF_00306567; iTF_00983244; iTF_00141921; iTF_01417988; iTF_00140872; iTF_00982570; iTF_01417803; iTF_00140685; iTF_00734189; iTF_00142094; iTF_00141458; iTF_00142707; iTF_00982387; iTF_00734036; iTF_00983063; iTF_00142553; iTF_00141307; iTF_00216494; iTF_00216680; iTF_00962606; iTF_00962787; iTF_00874063; iTF_00873889; iTF_00222160; iTF_00221544; iTF_00222002; iTF_00221363; iTF_01498482; iTF_01498313; iTF_00963290; iTF_00963467; iTF_01539900; iTF_01539707;
90% Identity
iTF_00232081;
80% Identity
iTF_00684424;