Emex007299.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eufriesea mexicana
Gene Symbol
KLHL10
Assembly
GCA_001483705.1
Location
NW:8387-24410[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.6e-29 4e-27 93.7 0.0 3 109 74 181 72 182 0.95

Sequence Information

Coding Sequence
ATGGTGGCCAGCGACGCTGGGATCGCGTGGCTCGTCCGCGAGGCGATGGACGGCCGCGGAAGGATCAAGTTCAGGAAGCTGTCTCGCAACCGGATGTCGCGAGCCGCCGTTTCCGCTACCAAGCTGAAGCAGTGCGTCAGGAAGCAGCCGGCTAAAATACGGAAATGCATGTGCCTGCCGTCCAATTACGCCCTCGTTGAATTCCCTGTAGTCTGGTCCGAGCTCAGGGCCAACCAGCAATTGTGCGACGGTGTAATCAGATGCGCCACGGGTCACGTTTTCCCCGTGCACCGCGCCATTTTGTCAGCGGTCAGCCCGTACTTCAAGGCGCTTTTCACCAACAGTCTGAAAGCTGGGAAAACAGAGACCACGGAAGTCGCGATCGATTCGGTACCCGGGAAAATTTTCAGCCTGATCCTTGATTACGCTTACACAGGCACATGCAATGTGAATGCCGACAACGTCGAGCAACTTCTACCCCTGGCTGATCAGTTCGAGGTCCTTGGAGTCGTGCAGCTCTGTTGTCAGTTCCTGCTGCAAGAACTTCGGCCAGAAAATTGTTTAGGGATCTTCAAATTCGctcgccactatttctgccgcGACCTGGAGGAGAAGGGCCGGAAATACATTCGCCATCACTTTAAGCGGATACTGCAAGAGAGCCCGGAATTCAAAGAGCTGACGAGCAAGGAACTCGAGGCGATTCTACGTGACGACGAGCTGAATGTTAAAAACGAAGAAATAGTTTTCGAGGCCGTTAAAACCTGGCTGGAGCATAACGTGGAAGAAAGGAGGCCCTATTTGCCTAGGCTCTTGAAATGTGTGCGCTACGGTTTGATGAGCTACAACTACTTCGCGAACAATGTCCTCACGTGGAAGATCATCGATGATGACGAGCTGAGTGACGAGTCATGCCAGCAAGTGATAGGTCCCGCTAACCAGTACCTGAAGGAACAGGAAGCGAGGCAAGGGAGCGGCGAGATCGATCTGAAGAACCCCCTATCCAAGCCTCGAATCCCCTATGAGATCCTGTTCGCGATCGGCGGATGGAGCGCCGGTTCCCCGACGAATTTCGTAGAGACTTACGACACGAGAGCTGACAGATGGTTTCTATCAGTGAATACGGACGTGACGCCGAGGTCCTACCACGGCTTGTGCACGTTGAACAATTTGATCTACATGATCGGCGGGTTCGACGGCAACCAGCACTTCAACACGGTCAGATGCTTCGATCCGGTCACGAGGGAGTGGCGTGAACGGGCCTGCATGTATCACGCGAGGTGTTACGTCAGCGTTTGCACCCACGgaggaaagatctacGCTCTCGGCGGGTACAATGGCCGGACCAGATTGAGCTCCGGGGAAAGATACGAACCGCAAAGGAACCAATGGGAGATGATACCTCCGATGCATCGGCAGAGGTCGGACGCGAGCGCGGCAGCCTTGCAGGACAAGATTTACATCGTCGGCGGTTTCAGTGGTCGCGAAGTTCTCAATTCCGCAGAGGTGTTCGACGTGGAGACCAATCAGTGGAGCTACATCCATCCCATGATCGACCCGCGATCCGGCGTGTGTCTGGTCGCGTTTCGAGACAGCCTTTACGCTCTGGGCGGCTTCAACGGATTCATCAGGCTCAGCTCTGGGGAGCGTTACAATCCGAATCATTCGGAGGATTGGCACGCGGTCCCGGAGATGTTCAGCCCCCGCAGCAATTTCGCCACGGTCATTCTGGACGACATGATATTCGTCGTCGGTGGATTCAATGGATCCACGACGATTGCATACGCGGAATGTTACGACCCAGACAGTAACGAATGGTACGATGCATCGCCGATGAATCTGAATCGAAGTGCCCTAAGTGCCTGTGTTATCGCTGGCCTGGCGAACGCACGCGAGTATTCTTATCACGGCAAGGCGCGAGATCTTGGCCAAGGTCAAGCTTCGTCAGAGAAtcaacagaaatccacccagggTGGAGAAGGCGCTGCTGAAACAAATGCGAGCATTTCCACCGAAGAAGGGGTGAACTTCAACGAACAAGTTCCAAGGGAGGTCAGCTCTATGAACGAGATAGCTGAGAATGTCGGCAATTATCTAGGATAA
Protein Sequence
MVASDAGIAWLVREAMDGRGRIKFRKLSRNRMSRAAVSATKLKQCVRKQPAKIRKCMCLPSNYALVEFPVVWSELRANQQLCDGVIRCATGHVFPVHRAILSAVSPYFKALFTNSLKAGKTETTEVAIDSVPGKIFSLILDYAYTGTCNVNADNVEQLLPLADQFEVLGVVQLCCQFLLQELRPENCLGIFKFARHYFCRDLEEKGRKYIRHHFKRILQESPEFKELTSKELEAILRDDELNVKNEEIVFEAVKTWLEHNVEERRPYLPRLLKCVRYGLMSYNYFANNVLTWKIIDDDELSDESCQQVIGPANQYLKEQEARQGSGEIDLKNPLSKPRIPYEILFAIGGWSAGSPTNFVETYDTRADRWFLSVNTDVTPRSYHGLCTLNNLIYMIGGFDGNQHFNTVRCFDPVTREWRERACMYHARCYVSVCTHGGKIYALGGYNGRTRLSSGERYEPQRNQWEMIPPMHRQRSDASAAALQDKIYIVGGFSGREVLNSAEVFDVETNQWSYIHPMIDPRSGVCLVAFRDSLYALGGFNGFIRLSSGERYNPNHSEDWHAVPEMFSPRSNFATVILDDMIFVVGGFNGSTTIAYAECYDPDSNEWYDASPMNLNRSALSACVIAGLANAREYSYHGKARDLGQGQASSENQQKSTQGGEGAAETNASISTEEGVNFNEQVPREVSSMNEIAENVGNYLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00676107; iTF_00140673; iTF_00221345; iTF_00221985; iTF_00215106; iTF_00761058; iTF_00217155; iTF_01069060; iTF_00088133; iTF_00217829; iTF_00219877; iTF_01169253; iTF_00214470; iTF_00225318; iTF_00231398; iTF_00232678; iTF_01122534; iTF_01539688; iTF_00142537; iTF_01066345; iTF_01123145; iTF_00230763; iTF_00084652; iTF_00141293; iTF_00218509; iTF_01067693; iTF_00215790; iTF_00223279; iTF_00225999; iTF_00963279; iTF_01067023; iTF_01070448; iTF_00118097; iTF_00222609; iTF_00141906; iTF_00964562; iTF_00228051; iTF_00684852; iTF_00228757; iTF_00087286; iTF_00963926; iTF_00226679; iTF_00088920; iTF_00220665; iTF_00961913; iTF_00085498; iTF_00229434; iTF_01065658; iTF_01069754; iTF_00223963; iTF_00224635; iTF_00227355; iTF_00230109; iTF_00233309; iTF_01068381; iTF_00219198; iTF_00216479; iTF_00232063; iTF_01454269; iTF_00982371; iTF_00983047; iTF_00873876; iTF_01417789; iTF_01120299; iTF_01424459; iTF_00360302; iTF_00360992; iTF_01071089; iTF_00962595; iTF_00086408; iTF_00862666; iTF_00762639; iTF_00625586; iTF_00184019; iTF_00763315; iTF_00966099; iTF_00306368; iTF_00866101; iTF_00866787; iTF_00865419; iTF_00861261; iTF_00864731; iTF_00863358; iTF_00861983; iTF_00864064; iTF_00183362; iTF_00109925; iTF_00868968; iTF_01245323; iTF_00264398; iTF_00729428; iTF_00730868; iTF_00769781; iTF_00280054; iTF_00867543; iTF_00280665; iTF_01254907; iTF_00265118; iTF_00860488;
90% Identity
iTF_00141906;
80% Identity
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