Basic Information

Gene Symbol
-
Assembly
GCA_963082485.1
Location
OY720049.1:2906232-2912382[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 42 0.011 1.2 10.9 0.9 1 23 53 75 53 75 0.97
2 42 0.99 1.1e+02 4.7 0.6 3 23 105 126 103 126 0.87
3 42 3.8 4.4e+02 2.9 1.4 2 23 147 169 146 169 0.89
4 42 0.0002 0.023 16.3 5.0 1 23 174 197 174 197 0.95
5 42 0.0031 0.35 12.6 3.3 1 23 201 224 201 225 0.95
6 42 0.0096 1.1 11.0 0.6 3 23 228 248 226 248 0.96
7 42 0.0069 0.79 11.5 0.4 1 19 254 272 254 274 0.93
8 42 0.014 1.6 10.5 1.3 1 23 328 351 328 351 0.95
9 42 0.22 26 6.7 0.3 1 23 422 445 422 445 0.94
10 42 0.0052 0.6 11.9 0.2 2 23 451 473 450 473 0.93
11 42 0.0028 0.32 12.7 0.6 1 23 478 501 478 501 0.96
12 42 0.026 3 9.7 0.4 2 23 507 529 507 529 0.95
13 42 0.0025 0.28 12.9 6.1 1 23 533 556 533 556 0.97
14 42 0.033 3.8 9.3 2.4 2 23 563 584 563 584 0.96
15 42 1.1 1.3e+02 4.5 0.5 1 23 628 650 628 650 0.95
16 42 0.029 3.4 9.5 0.2 2 23 678 700 677 700 0.94
17 42 8.3 9.5e+02 1.8 3.9 2 23 721 743 720 743 0.94
18 42 8.7e-06 0.00099 20.6 4.5 1 23 748 770 748 771 0.96
19 42 0.0035 0.41 12.4 0.5 1 23 775 798 775 798 0.96
20 42 0.18 21 7.0 0.5 2 23 801 823 800 823 0.94
21 42 1.1 1.3e+02 4.6 0.1 2 19 830 847 829 850 0.93
22 42 0.0057 0.65 11.8 1.4 1 23 904 927 904 927 0.94
23 42 0.69 80 5.2 0.1 2 23 956 978 955 978 0.95
24 42 0.00048 0.055 15.1 0.3 3 23 1002 1023 1000 1023 0.97
25 42 0.00067 0.077 14.7 0.2 3 23 1030 1051 1029 1051 0.93
26 42 7.8e-05 0.0089 17.6 2.3 1 23 1056 1079 1056 1079 0.92
27 42 0.00025 0.029 16.0 0.4 2 23 1085 1107 1085 1107 0.95
28 42 0.00017 0.019 16.6 4.4 1 23 1111 1134 1111 1134 0.97
29 42 0.002 0.23 13.2 2.1 1 23 1192 1214 1192 1214 0.95
30 42 6.9 8e+02 2.0 0.0 2 23 1242 1264 1241 1264 0.84
31 42 0.031 3.5 9.4 0.1 2 23 1285 1307 1284 1307 0.95
32 42 0.001 0.12 14.1 0.5 1 23 1312 1335 1312 1335 0.96
33 42 0.0047 0.54 12.0 1.2 1 23 1340 1363 1340 1363 0.94
34 42 0.00052 0.06 15.0 0.3 2 23 1366 1388 1366 1388 0.96
35 42 0.001 0.12 14.1 1.2 1 23 1471 1494 1471 1494 0.92
36 42 0.47 54 5.7 0.1 2 23 1567 1590 1566 1590 0.94
37 42 0.00035 0.04 15.6 1.1 3 23 1597 1618 1596 1618 0.94
38 42 0.053 6.1 8.7 6.8 2 23 1623 1645 1622 1645 0.94
39 42 0.028 3.2 9.6 3.8 1 23 1650 1673 1650 1673 0.97
40 42 5.9e-05 0.0067 18.0 4.2 1 23 1677 1700 1677 1700 0.97
41 42 0.00064 0.074 14.7 0.3 3 23 1708 1728 1706 1728 0.96
42 42 1.8e-05 0.002 19.6 1.8 1 23 1734 1756 1734 1756 0.98

Sequence Information

Coding Sequence
ATGGACCCcattaaacgaggtgtgaagcaGCAAGTTgcaggtcggcaagatgaaaatGAGCCGACAAATGGGCACAAAGCTAATAGGATCATGAGGAAGAACCTGCAAATATTGCTTAACAACTCCACTGTAATACCTTTCAAATGGCGCGGGAGGTACATGTGCTTCTATTGCGGAAAACAAATAGACGAATACAGTCAGTTAACACAGCATACTAAAGCCCATGGCAGTTGTACTGAAAAGGATCGAGCGATTAGACTTGTGAAAGGCCAAAACGCGGAAATCAAATTTGATGTTTCCGAAGACATCAATTGTCTGCTTTGCCACGAAAGTTTTTCTGACATCGATACCATTACAGACCATTTCAGTTACGAGCATAAGTTAACGTACGACAAAAGGCGCGAATTCTCCATGACAGCGTATAGGCTTGTTGATCTCAAATGCCTCTTGTGCCCGGAGACTTTAGAAAATCTGTCCAGACTCATTAAGCATTGTAACCGTTACCACCGTACCAACTGCTTCATTTGTCATGATTGTGGCCAATCGTTTAATAAAAAGAGGGATCTGCGCTCCCATATACATTATTACCATAGACATGAGTATGTTTGCAAACagtgtaatttaaaatttaaagataaGGCTGCTTTCTTTAAACACAACATGCGACCACACCATGTTATTTGTGACATATGTTTTGAAAGGTTTTCCTCTAGCAAGAAAAGGCTTGTGCACATGCGTGAACACTATAAAAACGAAGATTTTAAATGCGGATATTGTGATAAGAAATTCGATACTAAAATCGCTGTGATGAATCATTTCGCACACTGCAAGGTGAAATTGAAGCATCGCAGTAAACTGTACAAAGAGTCTGCTTACCTTGACACTAGCAATAGGAAGCAGGTATCAGCGCATATTAAAGACAACCTCATATGCATAGTCAATAGTTCCACACTGTTACCTTTTAAGTATTTCTTAGGTACATTCAAATGTTTCTTTTGTAAATCAAACTATGTCGATAGCGATGATCTTAAAAAACACGTAAAAGCAGAACATCCTTCTTGCAGTGAAGATAATCTTAAATGGGTTAGGCTGTATGAGGGATATCATTTTAAAGTTGATATATCCTCACTTTCTTGTAAATTGTGTGTGAAGCCTATGCAGGATATAGAAGCTTTGTCCACACATTTAATAACGGAGCACAAAATTGATTACGATAAAACGTTTAACGCAAAATTACAACCGTtcaaattaattagtaacaaaTTCCCGTGCCTTTCTTGTAGTAAAACTTTCGAGATATTCGGAGATTTGTTGAAGCACAAAAGCGTAATACATTCTAAGAATATCACCGTTTGTATGTACTGTGGGAAACCGTTTAAAGCCATCACCAGTTTGAGAGTTCATATATCGCTGAAGCACAATCCCGATGGGTATAAATGTGAAATATGCAGCATGGAGTTCTCTACAGGGCACCTTCTGAGAGGCCATATGGGCAAAGTGCACGGTAAAAAGAAGGCGAAATGCCAAATATGTTCAGAGAAATTCACTTCTCCTTACATAATGAAGACTCATATGATGGAGGTCCATGAGAAAGGTTTTACGTGCGACCACTGCGGAAAAATGTTTACAAGTAAATGTTTCATGCTTGAACACGTTCGGCGGACGCATTTGAAGGAGAAGAACGCGGAATGTTCCATTTGCTTCGAAAGATTTTTCGATCATCGGCTTTTGAAGATGCATATGGTGAAGCATATTGGAGAGAGGAAATTTGGTTatgaataTGGGCCGGCAAAAGGGAAACATACCAGTAAAAAGAGGAGGCGAAATCTACAAACATTGTTCAACAACACCTCGATGATACCATTTAAATGGCGCAGCAAATTCATGTGCTTTTACTGCGGTGACGACATTGACGATTACAATGAGCTCAAAAAACATACCAAAGCTCACGGCGTTTGTTCGGATCGAGATAGAGCTATTAAACTCGTAAAATCTAAAGAGTCTGAAGTCAAAATCGATGTATCGAACATGACGTGTGAACTGTGCGATGAGTCTTTTAGCTATTTCGATGACATTGTTTCTCATTTGACAATGAAACACCAACTGCCTTATGATAAAGACTGTGACGTCAGTATCACGACATATCGCTTGGTTGATCTTAAATGTGTGTTCTGCGAAGAGAAATGTGTCAATTTTTCTAGACTAGTGAAGCACGTGAATCATAGTCACCCCATCAATTGTTTCGTGTGCCACGATTGTGAtcgaaagtttaataaaaagagAGACCTTGAGTCCCACATCCGCATCCACCACAGAAAAGAGTATAAATGTAAAAGGTGCCTCATGAATTTTCCTAACAATGCCGCTTTGCAGAAGCACAAAGCGCGCGCCCACGTTTCAATGTGCAATATTTGTTTTGAACCATTTACTTCGGATAGTAAGAAGTTGGATCACATGAAACAGGCGCATTTTGATAAAGACTTTCTAGAATGTGGTTTTTGCCAAAAAAGGCTGACTACAAAACTGGCACTCCTTAATCACGCGGGAAAATGCATTAAGCAGCAGTGCAAATCCGACACGCTAACTTATACAGACCCTAAAAAGTTAGGCGTTACCGATAAGAAGCCTTCTGTGTCGCAAATAAGAAGCAATATCGCTTGCATTGTCAATATGTCCACAGCATTACCATTTAAGTACTTTATGAATAAATTCAGATGTTTTTATTGTCCGAAAGATTTTATTGAATGTGACGATCTCAAGGAACACACCGTTATGGAGCATCCGTCCTGTAGTAGCAAATTAAAATCTTTACGACTTAGGAATAGGGAGCATGGCATTAAAGTGAAAATAGACATATCATCGTTATCATGTAAAATGTGTTTCGAACCGATGCAAGATTTGGACAATTTAATAAACCATTTGATTACTGAACACAAAGCTCAGTACGACAAGTCCGTCGACAACAATATGCAACCGTTCAAATTGATTAGGGATAATTTCGGATGCCCTTTCTGCGGTGAGGTGTACAGATACTTTAGCACTTTACTAAAGCATATCAGTACAAGTCACACGGAGAACAGAAACATATGTTCGTATTGCGGCATGTCTTTTAGAACCGATCCAAGTTTACGGGCTCACATCACGCTTAGACATAAGCCCAACGGCCACAAATGTAGCATTTGCGACAAGGATTTCACAACAAAACATGCGTTACGTGATCATTTGGGTAATGCGCACGGTAGTAAAGTAGCCAAATGCCAAGTCTGTTCCGAAATGTTTACATCTCAGTACGCGATGCAGAGGCACATGATTAACGTCCACGCCACTGGTCACAAGTGCTCGTACTGTGGCAAAATGTTTACGAAAAACTCCTTCATGGTCAATCATGTTCGTCGTACACACCTTAAAGAGAAAAATGTGGAGTGCTCTAGGCACATTGACAGCAAGACAAATTTCTTTTCAGATGAAAAAGATCCAGCGCCTTACGAGGGATGTGCCTCTGAACGCAGGAGAAGAAACTTGAAAATATTATTCAACAACACTACAGTACTGCCATTCAAATGGCGCGGACGCTTCCTTTGTTTCTACTGCCCTAGAAACTTTTCGGAATATACAGAGTTGAGAAAGCACACCAGCACACATGGATCGTGCTCCACTAAAGACTATTCCTTAAAAATGATTAAAGGAAGCCGCATTGAAATTAAAGTTGATGTCTCCGATATGTCTTGTGAGGTGTGCAATGAACCGTTTGgagaattaaatgaaattatagaCCATCTGATCGGCAAACATAACATGGAGTATGATAAAACTGTCGAAATACCATACCAGAGTTACAGACTTGTCGATATGCGATGTTTAGTTTGCGAGGAGAAGTTTTCATACTTCGGATATCTGATAAGTCACGTAAACATTGCTCACCCTCAGAACTGTTTCATTTGTGACGAATGTGGAGTCACGTTCAACAAGAAAAGAGGTTTGGCAGTCCACTTCAGGTATTACCATAGAAAGGGCGGTTATCTCTGCGATCAGTGTGTGAAGAACTTTGAGAGCTTCTATTTGTTACGAAAACATCAGAATAACGTTCATTTTAGAAAGTGTAAGAATTGTAATTTGCGTTTTGCATCGCTAGCTTTACTGCAAAAACACATTCTTATAGAACACCCTGATGATGGAAGCTTGAAGTGTGAGTTTTGCGCGAAGCAGTGCCATTCTCAACAAGGCTTAATTCAACATAAGAGCAAGTGTAGAGTGAAGCTCACAATCTCTGTCGACGAACTGACTGACAAGTTTCTGCTAACGGAAAATAGTTCGGAGCCtaagaagaaacaaaatgtGAAACAGATCAGGCAGAACATACAGTGCGTCTTGAACATGTCAACAGCTGTGCCTTTCAAGTTCTTCTCCAAGTTCTCTTGCTTTTATTGCTCGAAAAAGTTTGTCGATTTCGATGATCTACGAAATCATACTGCAGAAGAACACCCAGTTTGTGATTTGCAATCTAAATCGATGATGAATTGTAAAGGCGAAAGAGTCAGTGTCAAAATAGATGTCAACTCATTGAGTTGTAAAGTCTGTTGCCAAAACATGGACAGTCTAAACAACCTCGTTGATCATTTGATCACTGATCACAAGGTCGATTACGACAAATCGGTTGTAGGTTGTTTGGAGCCATTCATAATAACTAAGGACAATATCCCCTGCCCCTTATGTCCTGATCGGGTGTTCAAATATTTTGGAATACTTCAGCGCCATATGAACTCTGAGCATAGCAACAACAAACGGATATGCGACTTTTGCGGGCGCAGTTTCAAGAACGTGGCCCATTTACGCGTCCACTTGTCGTATACGCACACCGGTTCATGCGAATGTAGCACTTGCGGCGTTAAATTTAAGAACCAATGGTGTTTGGCGAGGCATCGTGCGAAATGTCACGACGCAAAAGACTACAAATGTTCAAAGTGTCCAGAGCAATTTCAGTCTGAATACCATAAACAGAAGCACTTGATTAAAATGCACAATATCGGGCACAAATGTGAGCAATGCGGGAAGATGTTTACGAGAAATTCGTTCATGAAGGATCATGTGAGGAGGACGCATTTGAAGGAGAAGAATGTCATATGTTCCGTTTGCGATGAGAAGTTCTTTGATAACTACCTTCTGAAGCTGCATATGGTAAAGCATGAAGGGGAGAGACGGTTTAGTTGCACAATTTGTGGTAAAGCGTTCCTCAGGCGAAGCAATCTGCATTCTCATATGGAAATGCACAAGAAATATGGCCACGTTGATAGCTTGATACATGATATTATTGAATAG
Protein Sequence
MDPIKRGVKQQVAGRQDENEPTNGHKANRIMRKNLQILLNNSTVIPFKWRGRYMCFYCGKQIDEYSQLTQHTKAHGSCTEKDRAIRLVKGQNAEIKFDVSEDINCLLCHESFSDIDTITDHFSYEHKLTYDKRREFSMTAYRLVDLKCLLCPETLENLSRLIKHCNRYHRTNCFICHDCGQSFNKKRDLRSHIHYYHRHEYVCKQCNLKFKDKAAFFKHNMRPHHVICDICFERFSSSKKRLVHMREHYKNEDFKCGYCDKKFDTKIAVMNHFAHCKVKLKHRSKLYKESAYLDTSNRKQVSAHIKDNLICIVNSSTLLPFKYFLGTFKCFFCKSNYVDSDDLKKHVKAEHPSCSEDNLKWVRLYEGYHFKVDISSLSCKLCVKPMQDIEALSTHLITEHKIDYDKTFNAKLQPFKLISNKFPCLSCSKTFEIFGDLLKHKSVIHSKNITVCMYCGKPFKAITSLRVHISLKHNPDGYKCEICSMEFSTGHLLRGHMGKVHGKKKAKCQICSEKFTSPYIMKTHMMEVHEKGFTCDHCGKMFTSKCFMLEHVRRTHLKEKNAECSICFERFFDHRLLKMHMVKHIGERKFGYEYGPAKGKHTSKKRRRNLQTLFNNTSMIPFKWRSKFMCFYCGDDIDDYNELKKHTKAHGVCSDRDRAIKLVKSKESEVKIDVSNMTCELCDESFSYFDDIVSHLTMKHQLPYDKDCDVSITTYRLVDLKCVFCEEKCVNFSRLVKHVNHSHPINCFVCHDCDRKFNKKRDLESHIRIHHRKEYKCKRCLMNFPNNAALQKHKARAHVSMCNICFEPFTSDSKKLDHMKQAHFDKDFLECGFCQKRLTTKLALLNHAGKCIKQQCKSDTLTYTDPKKLGVTDKKPSVSQIRSNIACIVNMSTALPFKYFMNKFRCFYCPKDFIECDDLKEHTVMEHPSCSSKLKSLRLRNREHGIKVKIDISSLSCKMCFEPMQDLDNLINHLITEHKAQYDKSVDNNMQPFKLIRDNFGCPFCGEVYRYFSTLLKHISTSHTENRNICSYCGMSFRTDPSLRAHITLRHKPNGHKCSICDKDFTTKHALRDHLGNAHGSKVAKCQVCSEMFTSQYAMQRHMINVHATGHKCSYCGKMFTKNSFMVNHVRRTHLKEKNVECSRHIDSKTNFFSDEKDPAPYEGCASERRRRNLKILFNNTTVLPFKWRGRFLCFYCPRNFSEYTELRKHTSTHGSCSTKDYSLKMIKGSRIEIKVDVSDMSCEVCNEPFGELNEIIDHLIGKHNMEYDKTVEIPYQSYRLVDMRCLVCEEKFSYFGYLISHVNIAHPQNCFICDECGVTFNKKRGLAVHFRYYHRKGGYLCDQCVKNFESFYLLRKHQNNVHFRKCKNCNLRFASLALLQKHILIEHPDDGSLKCEFCAKQCHSQQGLIQHKSKCRVKLTISVDELTDKFLLTENSSEPKKKQNVKQIRQNIQCVLNMSTAVPFKFFSKFSCFYCSKKFVDFDDLRNHTAEEHPVCDLQSKSMMNCKGERVSVKIDVNSLSCKVCCQNMDSLNNLVDHLITDHKVDYDKSVVGCLEPFIITKDNIPCPLCPDRVFKYFGILQRHMNSEHSNNKRICDFCGRSFKNVAHLRVHLSYTHTGSCECSTCGVKFKNQWCLARHRAKCHDAKDYKCSKCPEQFQSEYHKQKHLIKMHNIGHKCEQCGKMFTRNSFMKDHVRRTHLKEKNVICSVCDEKFFDNYLLKLHMVKHEGERRFSCTICGKAFLRRSNLHSHMEMHKKYGHVDSLIHDIIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01335244;
90% Identity
-
80% Identity
-