Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.069 47 5.5 0.0 21 52 31 62 14 64 0.84

2 9 0.0068 4.6 8.7 0.0 21 48 87 114 83 119 0.86

3 9 1.6 1.1e+03 1.1 0.0 22 46 116 140 112 148 0.83

4 9 2.1 1.4e+03 0.8 0.0 22 52 144 174 139 175 0.83

5 9 3 2e+03 0.3 0.1 21 45 171 195 163 202 0.78

6 9 0.23 1.6e+02 3.8 0.0 21 48 199 226 194 230 0.86

7 9 0.29 2e+02 3.5 0.0 21 43 227 249 223 254 0.91

8 9 0.34 2.3e+02 3.3 0.0 22 44 256 278 252 283 0.90

9 9 0.71 4.8e+02 2.3 0.0 21 46 283 308 280 310 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.069	47	5.5	0.0	21	52	31	62	14	64	0.84
2	9	0.0068	4.6	8.7	0.0	21	48	87	114	83	119	0.86
3	9	1.6	1.1e+03	1.1	0.0	22	46	116	140	112	148	0.83
4	9	2.1	1.4e+03	0.8	0.0	22	52	144	174	139	175	0.83
5	9	3	2e+03	0.3	0.1	21	45	171	195	163	202	0.78
6	9	0.23	1.6e+02	3.8	0.0	21	48	199	226	194	230	0.86
7	9	0.29	2e+02	3.5	0.0	21	43	227	249	223	254	0.91
8	9	0.34	2.3e+02	3.3	0.0	22	44	256	278	252	283	0.90
9	9	0.71	4.8e+02	2.3	0.0	21	46	283	308	280	310	0.91

Coding Sequence: ATGTCTGGTAAGAAACAATTTACATGTGCTGAGTGCGATAAGACATTTACAGATCCGAGTAGTTTGAAATGTCACATGCGGATTCACACCGGCGAGAAGCCATTCAAGTGCGCtgagtgttttaaatcatttacgTATTCAAGCTCTTTAAGGTACCACATGTACATTCACAATGGTAAAAAGCCATTCAAATGCGTGGAGTGTGATAAGTCATTCGTAGCTTCAACTAGTTTAAGAAATCATATGGTGGTTCACACTGgcgaaaagccatttaaatgtattgtgtgttttaaaacattcacaCAATCGGGCCATTTAAAATCACACATGatgattcatacaggtgaaaagccgTTCAAATGTGCTGAGTGTGATATAACATTCAAGAGAGGCTGGGAATTAACAAAACACTTAAGAATCCACAatggtgaaaaacattttaaatgttctgtgtgtgataaattattcatagatTCAAGTGGTTTAAAAAGTCACATGCGGATTCATACTaatgaaaagccatttaagtgCGCTGAATGTTTTAAACCATTCAGACGTCTAAGTAGTTTAAATGTGCATACGAGGATTCACAccggtgaaaagccatttaaatgtgtcgaATGTGACATACGGTTCAGAGAATCGTCTAAACTGACcaaacacatgaggattcacactggcgaAAAGCCGTTCAGATGTTCCAGGTGCGATAAGACGTTCAGAGATTCAAGCACTTTAAAGAAACATACGTGGACTCATTtgggtgaaaagccatttaagtgCTCTGCATGTGTTAAAACATTCGCAGATCCAAGCAGCTTAAGAAGACATGTGCTGAATCACACTGGAGAGAAACCGTACAAATGTGTAGAGTGCAATAAAGCATTCACTGTTTCAAGTAGTTTGAAAAAACATATGCAACTTCATGTGGGTTAA
Protein Sequence: MSGKKQFTCAECDKTFTDPSSLKCHMRIHTGEKPFKCAECFKSFTYSSSLRYHMYIHNGKKPFKCVECDKSFVASTSLRNHMVVHTGEKPFKCIVCFKTFTQSGHLKSHMMIHTGEKPFKCAECDITFKRGWELTKHLRIHNGEKHFKCSVCDKLFIDSSGLKSHMRIHTNEKPFKCAECFKPFRRLSSLNVHTRIHTGEKPFKCVECDIRFRESSKLTKHMRIHTGEKPFRCSRCDKTFRDSSTLKKHTWTHLGEKPFKCSACVKTFADPSSLRRHVLNHTGEKPYKCVECNKAFTVSSSLKKHMQLHVG

Sequence clustering based on sequence similarity using MMseqs2