Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 3.3 2.3e+03 0.1 0.0 38 47 17 26 8 31 0.67

2 9 0.00065 0.44 12.0 0.0 21 51 28 58 25 61 0.87

3 9 2.7 1.8e+03 0.4 0.0 21 47 56 82 53 87 0.84

4 9 1.1 7.2e+02 1.7 0.0 21 44 84 107 80 111 0.81

5 9 0.041 28 6.2 0.0 21 45 112 136 106 139 0.89

6 9 0.039 27 6.3 0.0 21 52 140 171 137 172 0.88

7 9 0.12 79 4.8 0.0 23 44 170 191 166 195 0.90

8 9 0.21 1.4e+02 4.0 0.0 21 45 196 220 191 227 0.85

9 9 0.12 82 4.7 0.1 21 46 224 249 220 251 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	3.3	2.3e+03	0.1	0.0	38	47	17	26	8	31	0.67
2	9	0.00065	0.44	12.0	0.0	21	51	28	58	25	61	0.87
3	9	2.7	1.8e+03	0.4	0.0	21	47	56	82	53	87	0.84
4	9	1.1	7.2e+02	1.7	0.0	21	44	84	107	80	111	0.81
5	9	0.041	28	6.2	0.0	21	45	112	136	106	139	0.89
6	9	0.039	27	6.3	0.0	21	52	140	171	137	172	0.88
7	9	0.12	79	4.8	0.0	23	44	170	191	166	195	0.90
8	9	0.21	1.4e+02	4.0	0.0	21	45	196	220	191	227	0.85
9	9	0.12	82	4.7	0.1	21	46	224	249	220	251	0.89

Coding Sequence: ATGTCGGATTCAGACTTATTTAAATGTCCCGAGTGTGATCAGTCGTTTACGAATTTAAAGAGACATATGatgattcatacaggtgaaaagcccTTTAAATGTGGCGAGTGTTTTTCGTCCTTCACAGAATCGGCTAATTTAAAAAGACACATGAGAGTTCACACCGGAGAAAAGCCATTTCAGTGTGTCGAGTGTCTCAAATCATTCACAGCATCAACCGACTTAAAAATACACATGAGgtttcacacaggtgaaaagccgtTCAACTGTGTCGTGTGTTTTAAATCGTTCACAATATCTGGCGCTTTAACGATACACATGAGGACTCATACAGGTGAGAGGCCGTTTAACTGTGTTCTGTGTGGTAAGACATTTACAAGCTCTAgcaatttaagtaaacatttgCTGATTCACACCTCCGAAAACCCATTTAAGTGTGTCGAATGTCCCAAATCATTCACAACATCGAAAGATTTAAAAAGACATAcgaggattcacacaggtgtAAAGCCATTTACGTGCATcgagtgttttaaatcattcacacAGTCAAGTCATCTAAAAATACACATGAGGACTCATACGGGCGAAAAACcgtttaaatgtgttgagtgttttaaattattcacggCGTCAAGGTTTTTAGAAATACATATGAGGACTCACACAGGTGAGAAACCGTTTAAGTGTATCGAGTGCGATAAATCGTTCACACAATCCTCTCACCTCACGAGACACATTAGAATTCACACTGTGTGA
Protein Sequence: MSDSDLFKCPECDQSFTNLKRHMMIHTGEKPFKCGECFSSFTESANLKRHMRVHTGEKPFQCVECLKSFTASTDLKIHMRFHTGEKPFNCVVCFKSFTISGALTIHMRTHTGERPFNCVLCGKTFTSSSNLSKHLLIHTSENPFKCVECPKSFTTSKDLKRHTRIHTGVKPFTCIECFKSFTQSSHLKIHMRTHTGEKPFKCVECFKLFTASRFLEIHMRTHTGEKPFKCIECDKSFTQSSHLTRHIRIHTV

Sequence clustering based on sequence similarity using MMseqs2