Basic Information

Insect: Euclidia mi
Gene Symbol: THAP3
Assembly: GCA_944738845.2
Location: CALYKX020000317.1:862441-887345[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.093 26 7.7 0.9 1 23 351 373 351 373 0.96

2 10 0.0018 0.51 13.1 1.2 1 23 380 403 380 403 0.93

3 10 0.27 74 6.2 0.2 1 23 407 429 407 429 0.92

4 10 0.038 11 8.9 1.0 1 23 434 457 434 457 0.98

5 10 0.0026 0.72 12.6 0.7 1 23 461 484 461 484 0.96

6 10 0.16 44 7.0 0.2 3 23 575 596 573 596 0.96

7 10 0.0038 1.1 12.0 0.6 2 20 612 630 611 633 0.92

8 10 2.9e-05 0.008 18.7 3.1 1 23 639 661 639 661 0.99

9 10 0.00022 0.061 16.0 2.8 1 23 668 690 668 690 0.98

10 10 0.0035 0.97 12.2 4.9 1 23 696 719 696 719 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.093	26	7.7	0.9	1	23	351	373	351	373	0.96
2	10	0.0018	0.51	13.1	1.2	1	23	380	403	380	403	0.93
3	10	0.27	74	6.2	0.2	1	23	407	429	407	429	0.92
4	10	0.038	11	8.9	1.0	1	23	434	457	434	457	0.98
5	10	0.0026	0.72	12.6	0.7	1	23	461	484	461	484	0.96
6	10	0.16	44	7.0	0.2	3	23	575	596	573	596	0.96
7	10	0.0038	1.1	12.0	0.6	2	20	612	630	611	633	0.92
8	10	2.9e-05	0.008	18.7	3.1	1	23	639	661	639	661	0.99
9	10	0.00022	0.061	16.0	2.8	1	23	668	690	668	690	0.98
10	10	0.0035	0.97	12.2	4.9	1	23	696	719	696	719	0.90

Sequence Information

Coding Sequence: ATGTCCTTTGTTTGCTGCAGGTTCCCCAAGGACCCTAATCTTCGCACAGCATGGGTGGAAGCCCTCGGCATGTCAGACTGGGAGCCTAAAGACCGCAGCACCATATGCTCCGAACATTTCCGAAACGAGGACTTCTACGAGACCAAGAGAGGGCTGCGGAAGATTAAAGGTGGAGCCGTTCCAGTAGTGGCACAGGATTCAGCTGACGATCTTGATGCGCCGGCTGCGTTAAGAGTCTGCAGGATATGTCTGGCAATGGATGTCAGGATGTACGACTTCAGAGACCACAAGCTAGACTACATGTATGAACAAATAACTGGATTATTGACCACTACAGAAGAGCGGCTACCACAACGAGTTTGTTGGGAGTGCGCCGCTAGACTGACCTCAGCTGTGCGCTTCAGAAACGTAGCGCTGCGGAGTAACGCCATGCTACAGGATCTGTTACTGCCTGATGCTTATATTAAAATCCGGGACATAAAATCAATAAACAGAGTGCACTGCGGTTTAAAATCGCCTCTAATTCGTAAGATATTTGACAATAGAGATTACGATCTGCACATAAGAGATGTTTTTGTGAAAGAAGAGGAGGTGCAGAAAGAGTTAGATGGAGATGCGCAGGAGAACTGTGAGGGACTGGAGATTGAGGCTAAGGATCTTGTGCCTATCACTGAAGTGGAAGTTAAGGATGAAGGCAGCAGTAACGAAATATTTTTCGAAGAGTTCGATCATTTCGACGACGATGATGATAAAGCGCTAAGCGAAGTGTACGGTGAGAAAGTAAAAGAGAAAGAGAAAGTAAAAGTTAAGAAGAAGAAAGAAAAAGACAAAGATAAAGAGAAACCGGTTAAGAAGATAAAAGCTAAGAAGTTGGATGAAGATGATAATCCTGATTCTGCTACTGATAGGTATAAGAAAAACGACGTGAAACGCCGCCGTCAGACTGAAGCCTTAGACGAATCACTGTTCACAATCACCTCTCTCTCTTACGAGCAGCAAATCGAGGAGGTGCGAAAGAGACAGGAGAGCGGCAGCTACGTGAGCGCGCTGTACAAGTGCACCGTGTGCTACAGGGGGTTCCAGATCAAGGACCGGTACACCGCGCACGTCGTACGACATAGCGAGCAAAGCGGTGCATACGAGTGCTTCATATGCAAGACCCGTCTCAAGACTAGTCGCGCGCTGCGGAAGCACCTGACCGCGCAACACACCGAACAGTACAGCTGTAAGGGCTGTCCGTTCGTCACTAGGAACAGAGGTGTGGCGAGAGAGCACGAGAAATGGCACGCCGGCACCAAATACCAGTGTCCACATTGTGCGAGTGAGTTTGACAAGCTAACGACGTACATGGGCCACATTCGCATCAAGCACGTGTCAGACTTCGTGTGCGAGCTGTGCGGCTACACGTTCGTCAGTAAGAAGGGCATCGACGTGCACAAGAAGAAGAAACACAGGCTCGTTGACAAAACTGTGTCCCTAGAAGGCCCGTACTGCGAAGTTTGCGAAGTTAAGTTTGTATCAGAAGAGGCTCACGACAGACATCTCAAACTTTCATCAAGACATAGCAGTGATCATGATCCCAACCGCATCAGAAACGACTCACAAAGTATGAACGCGGAACGCAACGGTCGCGTAGTACGCCGCATAGAGAGACGGCCCGTCATACACGCGCGCGACGCCGCCGACCGACTGACCCAACACGAGCCGCACACACCTGTCAACTGTGAACAGTGTGGCATTCAGTTAAGAGATCTCCGGCTGTACGCGCAACACTTCAGAAGAGCTCACCCCGACAAGAATCGAACCAAGTACCCCGCGATGAAGACGCCCTGTATGTGTGAGCAGTGCGGCAAGATATTCCAGAGCATGGCGCTCCTAAAAGACCACATGTGGGTCCACACCGGCGAGAAGCGCTTCAAATGTGACCGCTGCACCAAGAGCTTCACTCAGAAGACGAACCTGGTGTTCCACATGCGCGTCCACAGCGCCACGCGGCCGACGTACGAGTGTCCGCTGTGCGGGAAACACTTCGCGTTCTTCAACAACAGGCGGCGCCACATGTTTATCCACACAGGCCTGAAGCCGTTCAAATGCGACACGTGCGGCAAATGTTTCACTACGTCCGGCGAACATAGAGCTCACGTCGAACATGTACATCTAAAGAAACCCTGGCCTAAGCGAGCGAGGCACAGGCGGGACTGGAAGTGTGACGCGCCCAGCGTTGAAGATTAG
Protein Sequence: MSFVCCRFPKDPNLRTAWVEALGMSDWEPKDRSTICSEHFRNEDFYETKRGLRKIKGGAVPVVAQDSADDLDAPAALRVCRICLAMDVRMYDFRDHKLDYMYEQITGLLTTTEERLPQRVCWECAARLTSAVRFRNVALRSNAMLQDLLLPDAYIKIRDIKSINRVHCGLKSPLIRKIFDNRDYDLHIRDVFVKEEEVQKELDGDAQENCEGLEIEAKDLVPITEVEVKDEGSSNEIFFEEFDHFDDDDDKALSEVYGEKVKEKEKVKVKKKKEKDKDKEKPVKKIKAKKLDEDDNPDSATDRYKKNDVKRRRQTEALDESLFTITSLSYEQQIEEVRKRQESGSYVSALYKCTVCYRGFQIKDRYTAHVVRHSEQSGAYECFICKTRLKTSRALRKHLTAQHTEQYSCKGCPFVTRNRGVAREHEKWHAGTKYQCPHCASEFDKLTTYMGHIRIKHVSDFVCELCGYTFVSKKGIDVHKKKKHRLVDKTVSLEGPYCEVCEVKFVSEEAHDRHLKLSSRHSSDHDPNRIRNDSQSMNAERNGRVVRRIERRPVIHARDAADRLTQHEPHTPVNCEQCGIQLRDLRLYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLVFHMRVHSATRPTYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKCFTTSGEHRAHVEHVHLKKPWPKRARHRRDWKCDAPSVED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00450559;
90% Identity: iTF_00677718; iTF_00281796; iTF_00282832; iTF_00281395; iTF_00282463;
80% Identity: iTF_00677718;