Basic Information

Insect
Euclidia mi
Gene Symbol
ibtk
Assembly
GCA_944738845.2
Location
CALYKX020000393.1:994274-1023039[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 4.2e-14 4.6e-11 45.0 0.0 7 79 551 622 544 627 0.91
2 12 1e-06 0.0012 21.2 0.0 9 44 743 778 737 791 0.85
3 12 1e-06 0.0012 21.2 0.0 9 44 799 834 793 847 0.85
4 12 9.2e-07 0.001 21.4 0.0 9 48 855 893 849 912 0.85
5 12 3.1e-05 0.035 16.5 0.0 14 44 916 946 904 959 0.81
6 12 1e-06 0.0012 21.2 0.0 9 44 967 1002 961 1015 0.85
7 12 3.2e-05 0.036 16.4 0.0 9 44 1023 1058 1017 1071 0.85
8 12 1e-06 0.0012 21.2 0.0 9 44 1079 1114 1073 1127 0.85
9 12 1e-06 0.0012 21.2 0.0 9 44 1135 1170 1129 1183 0.85
10 12 1e-06 0.0012 21.2 0.0 9 44 1191 1226 1185 1239 0.85
11 12 1.2e-11 1.3e-08 37.1 0.1 9 107 1247 1349 1241 1352 0.85
12 12 2.9 3.2e+03 0.5 0.1 78 107 1352 1381 1349 1384 0.87

Sequence Information

Coding Sequence
ATGAGTAAGCACAAGCCCGAGGTGGACTGCACCTCGCGCTGCAGGTCCCGGATTCATGGACAGATTATAACAAGTGCCATTACAAAGAGATCAATCAGTGATGAGGCTTTGGCAAGCTTTATTAAGGGAACATGTGCCAATTTTGTGAAGGCTTTTGACTTTGAGGGTCGTACAGCCTTACATACTGCTGCATCGCGCGGTAGAATTCGGCTAATGGACTGGCTAATCCGCCATTCGTCTGAGGCGTTTAAGAACGCGCGTGATCGCGAATCTGGCTACACTCCACTGCACAGAAGCATATTTTATGGACAGATAAATGCTGCTGTAGCTTTAATGAAGATTGGTGTGAACACAGACATAGTGGATAAAGACGACTACAGGGCCCTAGAGCACGCGATGCTGGACCGCCAGTACATGTACAAGCACGAAGGCAACGAGCCGAGTGAGGTGTATGTGTGGGGAAACAACTCCAACTACACCCTCGGCACTGGCACGCAGCAGGAGCGGAACACGCCAGAACTGCTCACCTGCTTCAATAGAGCCAACACTTGTGTCAAACAGGTGTGCCTCGGCAAGTTCCACAGCGTGTGGCTGGACGCCATGGGTGGCGCTTGGTGCTGCGGACAGCTGGCGCGCGCGGGCGGCCCGCACGCCACGGCGCTGCGCCCCACGCCGCTGCGCCGCGCCGAGCCCTGCGCCGCGCTCGCCATCACGCTCAACTCTACTATATTCTTGTTAGAGACCGGGGTGGTTCTCCAATACACGCTAAACAGCACAGACAACGTCAGCCAATCCAGCACAAAAGCTCCAACATCCATCAAGCTAGCGTCAGTTAAACCACTGATTAAGTTATCAGAACCGCTTGGTATTCGTGCGGCGCGTTCGCATGCTGTTGTGTGGAACACGCGCGCTGTGTACACGTGGGGGAACAATATAGGACAACTGGGACACTCTAACGAAGATAAAGTAGTCGCGACGCCTAAACGAGTGGCAATATCAATGAATAATAAAGAGGAAGCAGGCATTCAGTTAGTGGACGCGGCGGACGCAGCCACCGTCATCACCACCAGCCGCGGCGACGTCTACCTCCTGCACAAGTATATCTGCAAGAAGATCGCTATCAAACAGATAAATCTCCGTCAAGTATGCGTGGAGGCGAAAGTGAGCGAGACAGGCATATATTCTCGGGTGACCGTGCTTTTGCTGACCAACGTTGGACAATTGTTCATCTGGCAGGACACCACTAACAAACTTACGAGATGTGTATTCGGCCTAGTCCACCAGACAATAATAACCCACGTAGCGCTCACGCACGACGCTCTCTACTTCACGACTAAATACGGTGAAGCGTTCGTGGGCTCTATCTCACGCAAGGCCACGCCCACCGCCCAGCCGCAGCCTATCAAGAAAGAGAAGGAAAAGGACAACAAATCCGCCCTAGTCAAGTTTTTAGAAAAGGACGATTGCACGTCTGTGAGGATCGCGAAGATTTCTAATATATACAGGGCGGTTTCTATTGCTGTGGACAGTGAAGGGAATAATTTTGCGTGTCTGCAGATCAAACCAACCTGTGGATTACGATCTTTACCAGAACTGTCGCCCTCCAGTTTCGCCAAACACATGGAATCTCTTCGCGAAAGCGCAACTGAAGACGATTTGCTGCACGATGTCATATTCAAGGTTGGCGCCAAACTGTACCCCGCGCACATTTTCATAGTGGCGTCCAGCAGTGAATACCTCTATCAACTATACCAAGCCGCGCGCGCCAGCCCTGGCGATAAGCCCGAGATTACACTTGAAAACGTGCACCCAGATGCATTCGACCGAGTCATGAAGTATATGTATACGGGCTCCTGTGATGTGGCGGAACTAGGGCCTTGCCCGCTCAAAATTAGGAAGGAGGACCTAGTAGGAAAGAAGGACAAGGAAAATGAGGAAGAAGAGGAGGTGATTGAGAATCCCGCCGAAATATCAGCCTTCGAAGCATACAGCAAGCAAGGCGAGCGAGCGAAGCGTCGTCAACGGCGTAGCACGGACACTCCTCCTCGCACGCACGTGTACTGCGACCCGGTCAAACTCGTGCAGGCCACGGCTAAGAGACTGCAGGTTATGGCGCTGCATAAACTGCTCGATAAGTTCTATTACAAAGATGGCAACATTCGCCTAAAGGAGAGCGCTACATACACTAACGCCGCGACGTTGCCATGGCAACGCGACACTCTCGCCGAGCTAGTGGACACGAGCGTAGTGTCGCGGGACAACGTGCCCATCGCCGCGCACAAGTGCGTGCTCGCTGCCAGGCTCGAGTACTTCCAGGGAATGTTCATGCACTCTTGGACTGAGGTCAGTAGTATTGTTTATGTTACGTCGCCATGGCAACGCGACACTCTCGCCGAGCTAGTGGACACGAGCGTAGTGTCGCGGGACAACGTGCCCATCGCCGCGCACAAGTGCGTGCTCGCCGCCAGGCTCGAGTACTTCCAGGGAATGTTCATGCACTCTTGGACTGAGGTCAGTAGTATTGTTTATGTTACGTCGCCATGGCAACGCGACACTCTCGCCGAGCTAGTGGACACGAGCGTAGTGTCGCGGGACAACGTGCCCATCGCCGCGCACAAGTGCGTGCTCGCCGCCAGGCTCGAGTACTTCCAGGGAATGTTCATGCACTCTTGGACTGAGGTCAGTAGTATTGTTTATGTTACGTCGCCATGGCAACGCGACACTCTCGCCGAGCTAGTGGGCACGAGCGTAGTGTCGCGGGACAACGTGCCCATCGCCGCGCACAAGTGCGTGCTCGCCGCCAGGCTCGAGTACTTCCAGGGAATGTTCATGCACTCTTGGACTGAGGTCAGTAGTATTGTTTATGTTACGTCGCCATGGCAACGCGACACTCTCGCCGAGCTAGTGGACACGAGCGTAGTGTCGCGGGACAACGTGCCCATCGCCGCGCACAAGTGCGTGCTCGCCGCCAGGCTCGAGTACTTCCAGGGAATGTTCATGCACTCTTGGACTGAGGTCAGTAGTATTGTTTATGTTACGTCGCCATGGCAACGCGACACTCTCGCCGAGCTAGTGGACACGAGCGTAGTGTCGCGGGACAACGTGCCCATCGCCGCGCTCAAGTGCGTGCTCGCCGCCAGGCTCGAGTACTTCCAGGGAATGTTCATGCACTCTTGGACTGAGGTCAGTAGTATTGTTTATGTTACGTCGCCATGGCAACGCGACACTCTCGCCGAGCTAGTGGACACGAGCGTAGTGTCGCGGGACAACGTGCCCATCGCCGCGCACAAGTGCGTGCTCGCCGCCAGGCTCGAGTACTTCCAGGGAATGTTCATGCACTCTTGGACTGAGGTCAGTAGTATTGTTTATGTTACGTCGCCATGGCAACGCGACACTCTCGCCGAGCTAGTGGACACGAGCGTAGTGTCGCGGGACAACGTGCCCATCGCCGCGCACAAGTGCGTGCTCGCCGCCAGGCTCGAGTACTTCCAGGGAATGTTCATGCACTCTTGGACTGAGGTCAGTAGTATTGTTTATGTTACGTCGCCATGGCAACGCGACACTCTCGCCGAGCTAGTGGACACGAGCGTAGTGTCGCGGGACAACGTGCCCATCGCCGCGCACAAGTGCGTGCTCGCCGCCAGGCTCGAGTACTTCCAGGGAATGTTCATGCACTCTTGGACTGAGGTCAGTAGTATTGTTTATGTTACGTCGCCATGGCAACGCGACACTCTCGCCGAGCTAGTGGACACGAGCGTAGTGTCGCGGGACAACGTGCCCATCGCCGCGCACAAGTGCGTGCTCGCCGCCAGGCTCGAGTACTTCCAGGGAATGTTCATGCACTCTTGGACTGAGAGCAAACTCCTCTCAAAAGTGACATTACCAATCAACTACGGCATTCTACTGCCCGTTATCAACTTTCTGTACACGGACGCGTGCCCAGACCTCGACAATTGCGACAGTATCGACTTTATTTGTAATCTAATGATCGTCGCCGACCAGTTGTTCATTAGTCGGCTCAGAGAAATGTGCGAAGTTGCACTAGCCAACATGATCAACTTGAAAAATTGCACAGAACTTTGCCAATTCGCACACACTTACAACGCCACACAGCTCAAACAATGCTGCATGGAATTCATCTCACTAAACCTATGCAGCGTCCTAGAAAATAGATCTTTAGACTTACTAGAAGTTGAATTACTTGACGATATTACTAAGTATTACTGCAAATTTAATCCCATAATGTCATCTAGAGTAATAACACCGTTTTACAACGCGCCTGATGACGAAATAATCGAGGAATATGCTAAAAACTACCCAGTCAATCTAGAATTAACTGACGAAGAATATAAAAGAGATGACAGCATTATAGAAGTTCCTAAGAAAAGAAATAAACAAAAGAAGATTGAATATACTGAGAGCGAGAAGGAACGGATGAGATACGAATCCGTGAGTTCGGTGACTTCTTTAGATCTGTCCAACGAAATATCGGGTGATATTACTTTATCTTTAAGTAAAATTACTAAAGATTCCGAGAAAGGCGCTCGGGATAAACAAGAAAAGTGGATTGAGGTGCCTTCTTCACAACAAAAGCAACAAAAAGTGGTCCAAGCACGTCTGAAAGCAATAACCACCGCGAGGGATATATTGAGCGAAGCGCCCGCCGAATCGTTTGTAAAGCTTACTAAGAGTAGTTCTTCTAGTGCCATGACAATACAAGAAAAGCTAACCACCTCTTCGCGTATGTCGGTCTCGCCCAAAGATTCTCCTATAGCTGAAATGGCCAGAAGTCCACAGGGAAATGTGTTTATAAGTCATGTGGGACCAAAGTTATCTCAGAAGCAGAGGAAGAAGCTGGCCTTGCAGGGAAACGAATCTACCTCTCAAAGTGTTGAAGATTATTTTAGTAAAGTAAGCATTGGAAGTCCACCTGAGAAGCCTAAGAATCCGTGGAAGATTTGCGAAGCACCGGTGGCTAGCAGCAGTCCTAATTCTAAGGCAATTGAGTTTAATAAAATTCTGACTGATCAGAGGAAGCAAAAGGAGGACCATTCTCGAATAATGACTAAACCACTTACTTTGACACAGCTGGAAGACAAAGCCATCGAACAGTTAGAAAGATTCTATAACATCCATGAAGTAGATGACGAATTGATCACTGTGCGACGCATAGAGCTTCAAGTGTCTTCACCGCAATGGATCCACACTGCCTCAAAGTGA
Protein Sequence
MSKHKPEVDCTSRCRSRIHGQIITSAITKRSISDEALASFIKGTCANFVKAFDFEGRTALHTAASRGRIRLMDWLIRHSSEAFKNARDRESGYTPLHRSIFYGQINAAVALMKIGVNTDIVDKDDYRALEHAMLDRQYMYKHEGNEPSEVYVWGNNSNYTLGTGTQQERNTPELLTCFNRANTCVKQVCLGKFHSVWLDAMGGAWCCGQLARAGGPHATALRPTPLRRAEPCAALAITLNSTIFLLETGVVLQYTLNSTDNVSQSSTKAPTSIKLASVKPLIKLSEPLGIRAARSHAVVWNTRAVYTWGNNIGQLGHSNEDKVVATPKRVAISMNNKEEAGIQLVDAADAATVITTSRGDVYLLHKYICKKIAIKQINLRQVCVEAKVSETGIYSRVTVLLLTNVGQLFIWQDTTNKLTRCVFGLVHQTIITHVALTHDALYFTTKYGEAFVGSISRKATPTAQPQPIKKEKEKDNKSALVKFLEKDDCTSVRIAKISNIYRAVSIAVDSEGNNFACLQIKPTCGLRSLPELSPSSFAKHMESLRESATEDDLLHDVIFKVGAKLYPAHIFIVASSSEYLYQLYQAARASPGDKPEITLENVHPDAFDRVMKYMYTGSCDVAELGPCPLKIRKEDLVGKKDKENEEEEEVIENPAEISAFEAYSKQGERAKRRQRRSTDTPPRTHVYCDPVKLVQATAKRLQVMALHKLLDKFYYKDGNIRLKESATYTNAATLPWQRDTLAELVDTSVVSRDNVPIAAHKCVLAARLEYFQGMFMHSWTEVSSIVYVTSPWQRDTLAELVDTSVVSRDNVPIAAHKCVLAARLEYFQGMFMHSWTEVSSIVYVTSPWQRDTLAELVDTSVVSRDNVPIAAHKCVLAARLEYFQGMFMHSWTEVSSIVYVTSPWQRDTLAELVGTSVVSRDNVPIAAHKCVLAARLEYFQGMFMHSWTEVSSIVYVTSPWQRDTLAELVDTSVVSRDNVPIAAHKCVLAARLEYFQGMFMHSWTEVSSIVYVTSPWQRDTLAELVDTSVVSRDNVPIAALKCVLAARLEYFQGMFMHSWTEVSSIVYVTSPWQRDTLAELVDTSVVSRDNVPIAAHKCVLAARLEYFQGMFMHSWTEVSSIVYVTSPWQRDTLAELVDTSVVSRDNVPIAAHKCVLAARLEYFQGMFMHSWTEVSSIVYVTSPWQRDTLAELVDTSVVSRDNVPIAAHKCVLAARLEYFQGMFMHSWTEVSSIVYVTSPWQRDTLAELVDTSVVSRDNVPIAAHKCVLAARLEYFQGMFMHSWTESKLLSKVTLPINYGILLPVINFLYTDACPDLDNCDSIDFICNLMIVADQLFISRLREMCEVALANMINLKNCTELCQFAHTYNATQLKQCCMEFISLNLCSVLENRSLDLLEVELLDDITKYYCKFNPIMSSRVITPFYNAPDDEIIEEYAKNYPVNLELTDEEYKRDDSIIEVPKKRNKQKKIEYTESEKERMRYESVSSVTSLDLSNEISGDITLSLSKITKDSEKGARDKQEKWIEVPSSQQKQQKVVQARLKAITTARDILSEAPAESFVKLTKSSSSSAMTIQEKLTTSSRMSVSPKDSPIAEMARSPQGNVFISHVGPKLSQKQRKKLALQGNESTSQSVEDYFSKVSIGSPPEKPKNPWKICEAPVASSSPNSKAIEFNKILTDQRKQKEDHSRIMTKPLTLTQLEDKAIEQLERFYNIHEVDDELITVRRIELQVSSPQWIHTASK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-