Basic Information

Insect: Erynnis tages
Gene Symbol: Hr39
Assembly: GCA_905147235.1
Location: LR990075.1:2773938-2789232[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2 1.8e+04 -11.1 14.8 79 192 229 340 8 367 0.64

2 3 6.4e-08 0.00059 19.4 0.1 1 20 444 463 444 469 0.91

3 3 6.2e-43 5.7e-39 134.7 0.1 139 408 488 770 474 770 0.76

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2	1.8e+04	-11.1	14.8	79	192	229	340	8	367	0.64
2	3	6.4e-08	0.00059	19.4	0.1	1	20	444	463	444	469	0.91
3	3	6.2e-43	5.7e-39	134.7	0.1	139	408	488	770	474	770	0.76

Sequence Information

Coding Sequence: ATGAACGCCGCGATGTCGAGCGACGCGGACGCGGTGAAGATCGAGGGTGGTCATGTGTCTGTCACCACTATCAGCATGCCGGGTCCAGAAGCTAGTAATGGTCAGTTCTCCTACAGCTCGAGTGGAGTACGCATCAGCGTGTCTTCGGAGCCGCATGACGAGGACTCCACTGATGCGGAGATCTCCAAGATAGACTTCAATCAACATCAGTACGAGGTCAACATGAGGAACAAGAAGAAGCGCTCATTGAGCGGTCAGTGCGAGCCCAGTGAGCAGGAAAGGCCCATGTCCTGGGAGGGCGAGCTCTCAGACTCGGAGGAGATGGTCATAGACACCAGTGCAACCAACGATGAAAACAGCAGCTCTCTAGACCTTCAATCCTCAAGGGACTCGATCGATACGCTCCGGAACGTGACCATCAAGACGGAGCCCTTGAAGAACGAAGTGTTCCAGAGCCTGGACGACCAGAGGGTGTTGGACTTGAAGTACTCTGCGCCCTTGCAATCGCACCAAAGGAGTCTCAGTATGAACAGGATATCAGTACTAACGGACAACACATCACTGTCGCTGCCGAGACGGCCATCTTCACCGACGAACAGTGCCGCTTCACTCGCACTCTCAGACCAGTACGACCCCGCCTCGCACTTGATGCCTCATACCCCCAACACGGACATACAGAACCTCACTATTAAGAAGGAAACTCAGTTGTCAGAGTTGAAATGCGAGCCCAACATGGGCATGGACAAATTCCTAGGTCTGCGAGGCTCGCCGCTGCTGGGACGACTCCCGAGGGTCCAGTCCAGTGCCAGCACTGACTCCGCCGTGCATTCCATGTACACACACAGTGTGTACAGCAGTCCGTCCGCGAGCCCGCGCCCGTCCCGCCACTACACGCCTTCTCTGTCTCGTAACAACAGCGACGCCTCACACTCCTCCTGCTACTCGTATAGCTCCGAGTTCTCTCCCACGCACTCTCCAGTACAGAGCCGACATCCGCACGTGGTGTACAGAGAGGCGGCGGTGTTCCCCGCGTCGCCGGCCCACGACGAAGACGCTGATGCGGCTGAAGACAGGCTCCATCATCACCAGGGGATCAGTCGACAACAACTCATCAACAGTCCGTGTCCGATCTGCGGCGACAAGATCAGCGGGTTCCACTACGGGATATTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGGACGGTGCAGAACCGCAAGAACTACATGTGCCTGCGCGGCGGCAGCTGCCCCGTCACCGTGGCCACGAGGAAGAAGTGCCCCGCGTGCCGGTTCGACAAGTGCCTCGGCTGCGGGATGAAGCTGGAAGCGATTCGTGAAGACCGAACTCGAGGCGGCCGCTCGACGTACCAGTGCTCGTACTCTCTCTCCGGCGCCGCGTCCACGGGCTCGCTGCTGTCGGCCCACGCGCACCCACATTCCGTGTCATCGCTGCGACACGCGACCAGTCTCACTTCTGTAAACGGACCAGCGTCTTACAACAGTCGAGGAGAGTCGAGCAATAGCAGACTCACGCCGGACATTCCGCCGTTATTACAGGAAATAATGGACGTGGAGCACCTCTGGCAATACAACGAATCCGAACTGAACCGCCTCGGCAAGTCCACGGGCGGCGGCAGTCCCTCCGCCAACCCGCTGCTGGCCGCCAGCGGGATAACCGCCCAGAACTCCAGTGCGGACTTCTTGGCGGATCTGTGCAATATAGCCGACCACAGGCTGTACAAGATCATCGACGACCAGATCTGCCTGCTGATCAACAGCTGGTGCGAGCTGCTGGTGCTGTCGTGCTGCTACCGCGGCGTGGGCACGCCGGGCGAGGAATCGAACCCAGCGTCCGCGCAGCGCACCGGTGTCTTAACCGCTAATTTTTTTGAAGTGATAACTTCTTATGGAAAGATAAACCGCTTCGTAACGTACGGGTTAACTCCGTGCATCGAACGAATGCTCAGTTTCACCGACCACCTGAGGAGGTTGCGGGTCGACAGATACGAATATGTTGCGCTTAAAGTCATCGTACTTCTCACTTCAGACGCACCCGAATTACGCGAAGCCGAGAAAGTGCGCGCGTCGCAAGAGAAAGCGCTGGCGGCGCTGCAGGCGTACACGCACGCGCACTCGCCCGACGCGCCCGCCAAGTTCGGCGAGCTGCTGCTGCGTATACCCGAGCTGCAGAGGACTTGTCAGTTCTTCATGCAAGTGGGCAAGGAGATGCTGAACCCAGCCAACAAAGGCAAGGACGGCGAGGGCCCCAGCTTCAACCTTCTCATGGAACTGTTGCGGGGGGACCACTGA
Protein Sequence: MNAAMSSDADAVKIEGGHVSVTTISMPGPEASNGQFSYSSSGVRISVSSEPHDEDSTDAEISKIDFNQHQYEVNMRNKKKRSLSGQCEPSEQERPMSWEGELSDSEEMVIDTSATNDENSSSLDLQSSRDSIDTLRNVTIKTEPLKNEVFQSLDDQRVLDLKYSAPLQSHQRSLSMNRISVLTDNTSLSLPRRPSSPTNSAASLALSDQYDPASHLMPHTPNTDIQNLTIKKETQLSELKCEPNMGMDKFLGLRGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRPSRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQSRHPHVVYREAAVFPASPAHDEDADAAEDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGSCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYSLSGAASTGSLLSAHAHPHSVSSLRHATSLTSVNGPASYNSRGESSNSRLTPDIPPLLQEIMDVEHLWQYNESELNRLGKSTGGGSPSANPLLAASGITAQNSSADFLADLCNIADHRLYKIIDDQICLLINSWCELLVLSCCYRGVGTPGEESNPASAQRTGVLTANFFEVITSYGKINRFVTYGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPELREAEKVRASQEKALAALQAYTHAHSPDAPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKGKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00985246;
90% Identity: iTF_00673589;
80% Identity: iTF_00673589;