Basic Information

Insect: Eristalis tenax
Gene Symbol: L
Assembly: GCA_905231855.1
Location: HG993125.1:379276-403087[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3.9e-06 0.0006 20.7 1.7 1 23 297 319 297 319 0.98

2 17 0.33 50 5.2 5.8 1 23 325 347 325 347 0.98

3 17 1.7e-07 2.6e-05 25.0 3.1 1 23 353 375 353 375 0.99

4 17 7.9e-06 0.0012 19.7 0.3 1 23 381 403 381 403 0.98

5 17 0.86 1.3e+02 3.9 0.6 2 23 466 489 465 489 0.89

6 17 0.0019 0.28 12.3 0.4 2 23 506 528 505 528 0.97

7 17 0.014 2.2 9.5 1.4 1 23 609 631 609 631 0.97

8 17 0.00088 0.13 13.3 2.0 2 23 639 660 638 660 0.94

9 17 0.031 4.7 8.4 1.2 1 23 668 693 668 693 0.91

10 17 8.2 1.3e+03 0.8 0.3 1 19 698 716 698 718 0.92

11 17 0.001 0.16 13.1 2.9 1 23 785 807 785 808 0.96

12 17 0.00074 0.11 13.5 4.6 2 23 988 1010 987 1010 0.96

13 17 0.086 13 7.0 0.1 1 23 1016 1038 1016 1038 0.92

14 17 0.13 20 6.4 0.3 2 23 1046 1067 1045 1067 0.96

15 17 5 7.7e+02 1.5 0.4 2 23 1156 1177 1156 1177 0.92

16 17 0.0062 0.94 10.6 0.0 1 23 1187 1209 1187 1209 0.96

17 17 0.41 63 4.9 1.2 1 23 1216 1238 1216 1238 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3.9e-06	0.0006	20.7	1.7	1	23	297	319	297	319	0.98
2	17	0.33	50	5.2	5.8	1	23	325	347	325	347	0.98
3	17	1.7e-07	2.6e-05	25.0	3.1	1	23	353	375	353	375	0.99
4	17	7.9e-06	0.0012	19.7	0.3	1	23	381	403	381	403	0.98
5	17	0.86	1.3e+02	3.9	0.6	2	23	466	489	465	489	0.89
6	17	0.0019	0.28	12.3	0.4	2	23	506	528	505	528	0.97
7	17	0.014	2.2	9.5	1.4	1	23	609	631	609	631	0.97
8	17	0.00088	0.13	13.3	2.0	2	23	639	660	638	660	0.94
9	17	0.031	4.7	8.4	1.2	1	23	668	693	668	693	0.91
10	17	8.2	1.3e+03	0.8	0.3	1	19	698	716	698	718	0.92
11	17	0.001	0.16	13.1	2.9	1	23	785	807	785	808	0.96
12	17	0.00074	0.11	13.5	4.6	2	23	988	1010	987	1010	0.96
13	17	0.086	13	7.0	0.1	1	23	1016	1038	1016	1038	0.92
14	17	0.13	20	6.4	0.3	2	23	1046	1067	1045	1067	0.96
15	17	5	7.7e+02	1.5	0.4	2	23	1156	1177	1156	1177	0.92
16	17	0.0062	0.94	10.6	0.0	1	23	1187	1209	1187	1209	0.96
17	17	0.41	63	4.9	1.2	1	23	1216	1238	1216	1238	0.93

Sequence Information

Coding Sequence: ATGTCACGGAGAAAACAAGCTAAGCCAAGAGCATTCCTAAAAGAAGATGATAATAATGGAGAACACAACGGCAGCCTTCTGCCCATCGATCCTAAGGAAGAAGTCCTCTCGGACATGGACGGCGAACTTGATCAAGACGACCTCTTCGATGAGTTTCGAGAAATTGATGGGCACGGGGATGACACCGCCTGTAACCAGCAGCAGCACGCGACACTGATTGACAAACCACAACCGCAAGAAGAATTTTCACCGATTGAAAGCAAAAAATGTGAACTCTATTCGAACGACGGCGATAAATGTGTGGATGGCATAGACGACGACGAGCACAGCTCTGACAGTTTTTATTCGGATCTGTACTCCACACACACATCCTCAAGCTACTCGCCGTCGATGTCGGACGGAACTTTAACTCCAAACTCGCTGCACAACCACCATCAGGGCAATCAGCAGCATCATCAACGCCACCAGCAGCAGCGGCTGCACCACTTGCATTATCAGTGCGACCAGCAGAGCAGTGGCGGTGGTCAGAATCGCGACAGGCATCACAACCGACGTGTTTCAGCCATAAATGGAGCAACTGCCACTGGTCCGGGAATATCTGGGGACGGCGACGATGATGAGGATGATGACGGAGATGGGGACGAGGATGACGACGCCGCAAATTCTAGTGAAGAAAGGGTTTTCCTCTCGGCAAACGGTGCCAACGATGCTGTCACCAATACAAGTTCCACCACCACCACCAACACCGCGAGAAGCATCAGTGGCGCAACCGGCGAGCATTCCATGAAAATTCCAACGAAATTGCGGAAAATCGATAGGGATTCGGCAAAGTTGTTGGATAAGTTGACAAGTGATGGCATTAAGAGCGCGACCGACCGCGACGGATCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGCCTTGGGTATCTGAAGAAGCATGAACAGAGTCATGCGGAGCACCTTCCTTTCAAGTGTGACTACTGTGCTAGGCTTTTTAAGCACAAGCGATCGCGGGACAGGCACACTAAATTGCACACTGGGGACAGACGATATAGGTGCCCACACTGTGAGGCCGCTTTTTCTAGAAGTGATCATCTCAAGATTCACATGAAAACCCATGACAACCAAAAACCATTCCAATGCACCATATGTAACCGTGGATACAATACAGCTGCAGCCTTAACGTCGCACATGCAAAATCACAAGAAACAAGCTGCAATTCTTGCCGCTGGAGGCAACCCAGCTGTACTGAATTACAGTCCCAGATCGACGGGGTCGGGCTCAAGCAACAGCAGTCTGCAGAAACGACGATATGCTTCGATTGCGAACACAAAAAGTCCCAGTCCGAGTACCCTTGAATACGGCAAGCGCCTGCGTGGATCTTACATCACTTGCATGTACTGCACAAAGTCAGATTTCACATCCATGGAGCAGTTAAGCAGCCACATTCAGTCCATGCATGAGAAGGAAGCCATATCAAACCAGCCCGCTAACAGTGGTTTTCAAATGTCGTGCGAGTACTGCACGATGAAGTTTCCAAATATTCCGACGATGTTCCAACACATGAGAACAATTCATATTGACCGGCTGTCGAGCCCCAGCAGCTACTTTGAGCACTTTAATCGCCTGACCGCGGCGGGTCCCTTTAGTCCACGTTTGCCTACTCCGAAGGTTAACGAGACGAAGGTGAAAGTTGAGGAGTCAAGTCCAAAGGAGGCGGAGAAACCCGATGATGAACCCACAGACTTGAGCCAGAACAAGCGCACGGCCCGAACACCTTCGCAGGACTCAAGAGAGGCCTCTGAGAAGCCAGGAGTCTTCTTTTGCAACCAATGCAACGACGGGTTTCCAGATTTTGACAGTTTCCGAAATCACTTGAAATCACACATAACTCAGGGACTCAACTTGATTTGTCACCACTGCGGCCAGACCTTGAGGGATCAGAATGAGTTTGAGAGGCACGTCGTCTCGCACTTCCTTATAACTTGCTCCGAGTACAAGTGCACCGAGAAGAATTGTAATAAGTCGTACTTAAAACCGGAGGAACTACAGAAACACCTCTTCGATAGTCACATTCAAACTCTGTACAAATGCCTGCTGTGCTCCGACCATTTCGAAACCAAAGTGGCTATTCAAGTACATTTCGCATGCATTCATTCGCCAGAGAATAAGGTTTACCGTTGCTCAGCATGCATGGACACGTTTCACGGAGAGCAAGAGTTCCACGTACACGTCAAGACGCGACATCAGGGCACTATTGGATCGCCAATTCAGTGCATGTTCTGCAGAGCAGTTTGTTCCACAGAGCTCGAGATGCACTTTCATCTGGCAGCCCATGCCCGACAGTTCCGTTGTCCATCCTGTCCGGAAACGTTCCACGTCGAATTCCTTCTCGATCGCCACATGCAGACCCACCACGGGCAAAAGGACGCAGAATCCGCATCGGCTGTCAATCAGCCGTCCAATAACTCCATAAATCCACTCTACATGAGCGCTCTTTTCAACAAGCCAGCGCCATCGGCACAGAACAACAACAGCAGCATGATAGACTACAATGCATTTGCGCTGGGGAAGAATATTTTTGCATCAGCTACGAGCAACAAATTCTACAACCCTCTCCAGGTGGACACGGGCTCCTCGATGAAGCATCCCTCACTTGTGTACGCCAGTTTGAATCAGCATTACTTCGATACCAACCGCACCATCCTCGAGATGTACAACCAACATCAACAGGAGAAGCTCAGTGGGGCTGCAGCAGCCACTTACTTCAACAGCCCGAACAACAGCAACAGAGGGTCAATGAAACCGCAGCAGGAATCCAACAAGGCATCAGATCGAACTCTGGGCAGCACCGGTTTCAGCTGTGGCATGTGCGAACGCAATGATTTTCGAACAGAGGCGGAGATTCATTCGCATCGGAAAATCGTGCACAACCTCAAGACGGGGGTCAGCCTCCGTTGTGCCTACTGCAGTGGCAACTTTAAGTCCCGCAGTGAGCTGGAGCATCATATGAAGACTTGTCACAACTCTACCGGGAAGCACAAATGCCTGATTTGTGATGAAATATTCCCATCGCCGGCGATTCTCGCCGAACACAAGCTCCAGCACTCGAAGGTTGGTCAGTCTGGAAAGTGCTCCCACTGCGCCAAAGCACTGCCAGATGTGAGTTCTTTCAAGGGTCACCTTCTGGAGCACAACACTGAGGGGCAGATGCCAGTCCAGTGCATCTGCTGCCGTCAAACACTTCATTCGGACTTCGAAATAGGTCTCCATGCCAAATTTCATACAAAATCATCCTCTTCGTCCGAGAGCGTGTGCGCCTTGTGCCTGGAGTCGATCCCCAACACCTCGGACGCAAAGGTTTGCGAGAAGTGTTGTCGCAAGCACAACTTGAGCGGCAAGTTCAGCAGTCAGCGTAGCTTCGAAGGCGGAAACGGAGCATTGAGCTATGTGGAGAACCGATGTAACCTCTGTAAAATTATCATGCCACATGCGCAGAAACTGCAGGAGCATTTGGTGGAGCATACCTTCGCTGGGTGTGAGGACAGGGGCTTCACTTGTTACATTTGCTCTGCGGTTTTCACAGCTCCCGCCGGTTTGCTGAGCCATATGGCCGACCACGGGGCCAATTCACGACCTTATGACTGCAATCTTTGCAGCGAGAAATACTTTTTCCGTGCGGAGTTAGACCACCACCTGGTCGATCACGACATAAGGGACCGCCTAAAGAGTGTGGTTAGTGATGCCGCCGGCAGTAGTAGTAACACCGTCACAGAGCCGAGCAAAGTCTCGGAAGTGGGAAAGAAACCATTCGATGATCCGTCGGAAAAAGAGGTTGCTGCTAAAACGGAGCCGAAAACTGAAGGCATTGACGAGAAGCTGGCCGATGAGGATGACGACGAGTACATCGAAGTAGAAAAGGTCCCAGAAGTCCCACAGGACACTGTATGCAACCCCGAGAAGGACGACTAA
Protein Sequence: MSRRKQAKPRAFLKEDDNNGEHNGSLLPIDPKEEVLSDMDGELDQDDLFDEFREIDGHGDDTACNQQQHATLIDKPQPQEEFSPIESKKCELYSNDGDKCVDGIDDDEHSSDSFYSDLYSTHTSSSYSPSMSDGTLTPNSLHNHHQGNQQHHQRHQQQRLHHLHYQCDQQSSGGGQNRDRHHNRRVSAINGATATGPGISGDGDDDEDDDGDGDEDDDAANSSEERVFLSANGANDAVTNTSSTTTTNTARSISGATGEHSMKIPTKLRKIDRDSAKLLDKLTSDGIKSATDRDGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCDYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQAAILAAGGNPAVLNYSPRSTGSGSSNSSLQKRRYASIANTKSPSPSTLEYGKRLRGSYITCMYCTKSDFTSMEQLSSHIQSMHEKEAISNQPANSGFQMSCEYCTMKFPNIPTMFQHMRTIHIDRLSSPSSYFEHFNRLTAAGPFSPRLPTPKVNETKVKVEESSPKEAEKPDDEPTDLSQNKRTARTPSQDSREASEKPGVFFCNQCNDGFPDFDSFRNHLKSHITQGLNLICHHCGQTLRDQNEFERHVVSHFLITCSEYKCTEKNCNKSYLKPEELQKHLFDSHIQTLYKCLLCSDHFETKVAIQVHFACIHSPENKVYRCSACMDTFHGEQEFHVHVKTRHQGTIGSPIQCMFCRAVCSTELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHGQKDAESASAVNQPSNNSINPLYMSALFNKPAPSAQNNNSSMIDYNAFALGKNIFASATSNKFYNPLQVDTGSSMKHPSLVYASLNQHYFDTNRTILEMYNQHQQEKLSGAAAATYFNSPNNSNRGSMKPQQESNKASDRTLGSTGFSCGMCERNDFRTEAEIHSHRKIVHNLKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCAKALPDVSSFKGHLLEHNTEGQMPVQCICCRQTLHSDFEIGLHAKFHTKSSSSSESVCALCLESIPNTSDAKVCEKCCRKHNLSGKFSSQRSFEGGNGALSYVENRCNLCKIIMPHAQKLQEHLVEHTFAGCEDRGFTCYICSAVFTAPAGLLSHMADHGANSRPYDCNLCSEKYFFRAELDHHLVDHDIRDRLKSVVSDAAGSSSNTVTEPSKVSEVGKKPFDDPSEKEVAAKTEPKTEGIDEKLADEDDDEYIEVEKVPEVPQDTVCNPEKDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01542500;
90% Identity: iTF_00671192;
80% Identity: -