Basic Information

Insect: Eristalinus aeneus
Gene Symbol: L
Assembly: GCA_955652365.1
Location: OY019131.1:100216973-100224809[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 4.1e-06 0.0006 20.8 1.7 1 23 209 231 209 231 0.98

2 17 0.35 50 5.3 5.8 1 23 237 259 237 259 0.98

3 17 1.8e-07 2.6e-05 25.1 3.1 1 23 265 287 265 287 0.99

4 17 8.3e-06 0.0012 19.9 0.3 1 23 293 315 293 315 0.98

5 17 0.91 1.3e+02 4.0 0.6 2 23 378 401 377 401 0.89

6 17 0.0014 0.2 12.9 0.4 2 23 418 440 417 440 0.97

7 17 0.015 2.2 9.6 1.4 1 23 521 543 521 543 0.97

8 17 0.0029 0.42 11.8 2.7 3 23 552 572 551 572 0.96

9 17 0.00021 0.03 15.5 1.4 1 23 580 605 580 605 0.91

10 17 8.7 1.2e+03 0.9 0.3 1 19 610 628 610 630 0.92

11 17 0.0011 0.16 13.2 2.9 1 23 697 719 697 720 0.96

12 17 0.00078 0.11 13.6 4.6 2 23 901 923 900 923 0.96

13 17 0.091 13 7.1 0.1 1 23 929 951 929 951 0.92

14 17 0.045 6.5 8.1 0.5 2 23 959 980 958 980 0.96

15 17 6.6 9.5e+02 1.3 0.7 2 23 1069 1090 1069 1090 0.92

16 17 0.0048 0.7 11.1 0.0 1 23 1100 1122 1100 1122 0.97

17 17 0.046 6.7 8.1 1.2 1 23 1129 1151 1129 1151 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	4.1e-06	0.0006	20.8	1.7	1	23	209	231	209	231	0.98
2	17	0.35	50	5.3	5.8	1	23	237	259	237	259	0.98
3	17	1.8e-07	2.6e-05	25.1	3.1	1	23	265	287	265	287	0.99
4	17	8.3e-06	0.0012	19.9	0.3	1	23	293	315	293	315	0.98
5	17	0.91	1.3e+02	4.0	0.6	2	23	378	401	377	401	0.89
6	17	0.0014	0.2	12.9	0.4	2	23	418	440	417	440	0.97
7	17	0.015	2.2	9.6	1.4	1	23	521	543	521	543	0.97
8	17	0.0029	0.42	11.8	2.7	3	23	552	572	551	572	0.96
9	17	0.00021	0.03	15.5	1.4	1	23	580	605	580	605	0.91
10	17	8.7	1.2e+03	0.9	0.3	1	19	610	628	610	630	0.92
11	17	0.0011	0.16	13.2	2.9	1	23	697	719	697	720	0.96
12	17	0.00078	0.11	13.6	4.6	2	23	901	923	900	923	0.96
13	17	0.091	13	7.1	0.1	1	23	929	951	929	951	0.92
14	17	0.045	6.5	8.1	0.5	2	23	959	980	958	980	0.96
15	17	6.6	9.5e+02	1.3	0.7	2	23	1069	1090	1069	1090	0.92
16	17	0.0048	0.7	11.1	0.0	1	23	1100	1122	1100	1122	0.97
17	17	0.046	6.7	8.1	1.2	1	23	1129	1151	1129	1151	0.93

Sequence Information

Coding Sequence: ATGATGGCATTAAAAATGCTCTACCGCGGTCCAAGCTCTCGActggaaaatttaattgaaaagatTCAAGCCACTAAGGAAGTCAATAcagATCTGTATTCCACGCACACATCCTCCAGCTACTCGCCGTCGATGTCGGACGGGACGTTAACTCCAAACTCGCTGCACAACCACCATCAGAATcaccagcagcaacatcaaCGCCACCACCAGCAGCGGTTGCACCACTTGCATTATCAGTGCGACCAACAGAACAGTGGCGGTCAAACTCGCGACAGGCATCACAATCGACGTGTTTCAGCCTTAAATGGAGCAACTGCCTCTGGGCCGGGGGTTACTGGTGACggagatgaagatgaagacgaCGAGGGAGATGGGGACGAAGATGACGACGCCGCAAATTCTAGTGAGGAAAGGGTTTTCCTCTCGGCAAATGGTGCCAACGATGCTGTCACCGACACAacatccaccaccaccaccatcgcgCGTAGCATCAGTGGCGCAACCGGCGAGCATTCCATGAAAATTCCAACGAAATTGCGGAAAATCGATAGGGATTCGGCaaagttgttggataagttgacAAGTGATGGCATTAAGAGCGCGACCGACCGCGACGGATCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGCCTTGGGTATCTTAAGAAGCATGAACAGAGTCATGCTGAGCACCTTCCTTTCAAATGTGACTACTGTGCCAGGCTCTTCAAGCATAAGCGATCGCGGGATAGGCACACAAAACTGCACACCGGGGACAGACGATACAGATGCCCGCACTGCGAGGCTGCTTTTTCAAGAAGTGATCATCTTAAGATTCACATGAAAACTCACGATAACCAAAAACCATTCCAATGCACCATTTGTAATCGTGGATACAATACAGCAGCAGCATTGACGTCGCACATGCAAAACCATAAAAAACAAGCAGCAATACTTGCCGCCGGGGGAAACCCATCCGCCTTGAATTATAGTCCCAGATCTACGGGGTCAGGATCAAGCAACAGTAGCCTGCAGAAGCGACGATACGCTTCAATTGCCAACACAAAAAGTCCAAGTCCTAGCACCTTGGACTACGGCAAACGCCTACGGGGTTCCTATATCACATGCATGTACTGCACAAAATCCGACTTCACTTCAATGGAGCAGTTAAGTAGTCACATTCAGTCTATGCATGAAAAAGAGGCACTGTCCACCCAGGCGGCTAACAGTGGATTTCAAATGTCTTGTGAGTACTGCACGATGAAGTTTCCAAATATTCCGTCGATGTTTCAGCACATGAGAACGATTCACATTGATCGTCTCTCCAGTCCAAGCAGCTACTATGAGCATTTTAATCGCCTGGCCGCCGCTGGTCCTTTCAGTCCACGTCTGCCCAATCCGAAGGTAAATGAGACAAAAGTTAAAGTGGAAGAGTCGAGTCCAAAGGAGGCAGAAAAACCTGATGACGAGCCCACTGATTTAAGCCAAAATAAAAGGACAACACGAACACCGTCACAGGACTCCAGAGAGGCCTCGGAGAAGCCAGGCGTATTTTTCTGTAATCAATGCAACGATGGATTCCCGGACTTTGACAGCTTCCGGAACCACTTAAAGTCACACATAACTCAGGGGCTTAACTTGCTTTGCCACCACTGCGGGCAAACTCTTCGGGATCAAAACGAATTTGAGAGGCATGTAGTTTCACACTTCCTGATAACATGCTCCGAATACAAGTGCAGCGAGAAGAATTGTAATAAATCTTATTCAAAGCCCGAGGAGCTGCAGAAGCACCTCTTCGACAGCCATATACAGACCTTGTACAAGTGCTTGTTGTGTTCCGACCATTTCGAAACCAAAGTTGCAATTCAAGTTCACTTTGCGTGCATACACTCGCCAGAGAATAAGATATACCGTTGCTCAGCTTGCATGGACACTTTTCACGGAGAGCAAGAGTTCCATATACATGTCAAATCGCGTCATCAGGGCAACGTTGGATCTCCCATTCAGTGTATGTTTTGTCGAGCAGTTTGTTCCACAGAGCTGGAAATGCACTTTCACTTAGCAGCACATGCCAGGCAGTTCCGCTGCCCATCCTGTCCGGAAACATTCCATGTCGAATTTTTGCTCGACCGACACATGCAAACTCATCACGGACAGAAAGACGCCGAGTCCTCATCGGCTGTCAATCCGCCGTCCAGTAATTCCATAAATCCCCTTTATATGAACGCCCTGTTTAGCAAGCCCGCCTCATCAGCGCAGAACAATAACAACAGTATGATAGACTACAATGTGTTTACATTGGGAAAGAACATTTTCGCGAATGCAGCTAGTAACAAGTTCTACAACCCTCTCCAGGTGGACACCAGTGCTTCAATGAAGCATCCATCCTTAGTATACGCAAGTTTGAATCAACACTATTTTGACACCAACCGGACAATCCTCGAGATGTACAACCAACATCAGCAGGAGAAGCTGAGTGGAGCTGCAGCAGGCAATTACTTCAATAGCCCCAACAACAATAACAGAGGATCCCTGAAACCGCAGCAAGAATCCAATAAGTCGTCGACAGAAAGAACTTTGGGCGGGACTGGTTTTAGTTGTGGCATGTGCGAACGGAATGATTTTCGAACAGAAGCCGAGATACATTCGCATCGAAAAATTGTACATAACCTCAAGACGGGTGTCAGCCTCCGCTGCGCCTACTGCAGCGGCAACTTCAAATCACGTAGCGAACTGGAGCACCATATGAAGACATGTCATAACTCCACCGGGAAACACAAATGTTTAATTTGTGATGAAATATTTCCGTCGCCGGCTATTCTGGCCGAACACAAGCTTCAACACTCGAAGGTGGGACAATCTGGGAAATGCTCTCACTGTTCCAAAGCACTGCCCGATGTGACTGCTTTTAAGAGTCATCTTTTGGAGCACAACACAGAAGGCCAAATGCCAGTTCAGTGCATTTGCTGCCGTCAAACACTTCATTCAGACTTTGAAATAGGACTTCATGCCAAATTTCACACAAAATCATCGTCCTCCTCGGAGAGCGTGTGTGCCCTGTGTTTGGATTCCATTCCCAACACATCAGATGCAAAAGTCTGCGAAAAATGCTGTCGTAAGCATAATCTAAGCGGCAAGTTCAACAGCCAACGTAGCTTCGAAACTGGAAACGCGGCCTTAAGTTATGTTGAGAATCGATGCAACTTGTGCAAAGTCATAATGCCCCACTCTCAGAAGCTGCAGGAGCACTTGGTGGAACACACCTTTGCTGGTTGCGAAGACAGGGGTTTTACCTGCTACATTTGTTCTGCAGTTTTCACAGCTCCCGCCGGTCTTTTAAGTCACATGGCTGAGCACGGGGCCAATTCGCGGCCCTACGACTGCAACCTGTGTAGCGAGAAATTCTACTTTCGTGCGGAGCTAGATCACCACCTGGTCGACCACGAAATAAGGGACCATTTAAAAAGCTCTGCTAATGAAGGTACAGGTATTAGCGGCGGTCCCAGTGCAGAGGTCAATCAAGGCTCGGAGACTGGAAAAAAAGTATTTGACGAACCAATGGCAGAAGAAGCCACCCCCAAGGCAGAGCAGAAACCTGAATGCATGGACGAGAAGCTAGCAGACGAAGATGATGACGAGTACATTGAGGTGGAAAAAGTACCAGAAGTGCCGGTACAGGAAACTCCACGCAAAGCCGAGAAGGACGAATAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEVNTDLYSTHTSSSYSPSMSDGTLTPNSLHNHHQNHQQQHQRHHQQRLHHLHYQCDQQNSGGQTRDRHHNRRVSALNGATASGPGVTGDGDEDEDDEGDGDEDDDAANSSEERVFLSANGANDAVTDTTSTTTTIARSISGATGEHSMKIPTKLRKIDRDSAKLLDKLTSDGIKSATDRDGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCDYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQAAILAAGGNPSALNYSPRSTGSGSSNSSLQKRRYASIANTKSPSPSTLDYGKRLRGSYITCMYCTKSDFTSMEQLSSHIQSMHEKEALSTQAANSGFQMSCEYCTMKFPNIPSMFQHMRTIHIDRLSSPSSYYEHFNRLAAAGPFSPRLPNPKVNETKVKVEESSPKEAEKPDDEPTDLSQNKRTTRTPSQDSREASEKPGVFFCNQCNDGFPDFDSFRNHLKSHITQGLNLLCHHCGQTLRDQNEFERHVVSHFLITCSEYKCSEKNCNKSYSKPEELQKHLFDSHIQTLYKCLLCSDHFETKVAIQVHFACIHSPENKIYRCSACMDTFHGEQEFHIHVKSRHQGNVGSPIQCMFCRAVCSTELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHGQKDAESSSAVNPPSSNSINPLYMNALFSKPASSAQNNNNSMIDYNVFTLGKNIFANAASNKFYNPLQVDTSASMKHPSLVYASLNQHYFDTNRTILEMYNQHQQEKLSGAAAGNYFNSPNNNNRGSLKPQQESNKSSTERTLGGTGFSCGMCERNDFRTEAEIHSHRKIVHNLKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSKALPDVTAFKSHLLEHNTEGQMPVQCICCRQTLHSDFEIGLHAKFHTKSSSSSESVCALCLDSIPNTSDAKVCEKCCRKHNLSGKFNSQRSFETGNAALSYVENRCNLCKVIMPHSQKLQEHLVEHTFAGCEDRGFTCYICSAVFTAPAGLLSHMAEHGANSRPYDCNLCSEKFYFRAELDHHLVDHEIRDHLKSSANEGTGISGGPSAEVNQGSETGKKVFDEPMAEEATPKAEQKPECMDEKLADEDDDEYIEVEKVPEVPVQETPRKAEKDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01542500;
90% Identity: iTF_00671792; iTF_00672441; iTF_00673059;
80% Identity: -