Basic Information

Insect: Eristalinus sepulchralis
Gene Symbol: grau
Assembly: GCA_944738805.1
Location: CALYJE010000040.1:1162219-1167400[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.2 1.3e+02 3.4 0.1 2 23 269 291 268 291 0.92

2 18 0.037 4.1 8.2 0.5 6 23 300 317 299 317 0.99

3 18 0.022 2.4 8.9 5.6 1 23 323 345 323 345 0.98

4 18 7.6e-06 0.00083 19.8 1.6 1 23 353 375 353 375 0.99

5 18 1.3e-05 0.0015 19.0 0.3 2 23 382 404 381 404 0.95

6 18 2e-05 0.0021 18.5 0.4 3 23 412 432 411 432 0.96

7 18 0.0001 0.011 16.2 0.2 2 23 441 463 440 463 0.95

8 18 0.00069 0.075 13.6 0.1 1 23 470 493 470 493 0.94

9 18 0.0022 0.24 12.0 0.3 1 17 499 515 499 516 0.89

10 18 0.55 60 4.5 0.2 6 23 755 772 755 772 0.98

11 18 1.1e-05 0.0012 19.3 2.0 1 23 778 800 778 800 0.99

12 18 0.0079 0.86 10.3 6.4 1 23 808 830 808 830 0.98

13 18 2.5e-06 0.00028 21.3 0.3 1 23 838 861 838 861 0.96

14 18 0.0023 0.25 12.0 0.2 3 23 869 889 868 889 0.96

15 18 2.8e-05 0.003 18.0 0.8 2 23 898 920 897 920 0.97

16 18 0.00023 0.024 15.1 0.1 1 23 927 950 927 950 0.94

17 18 6.7e-07 7.3e-05 23.1 1.0 1 23 956 978 956 978 0.98

18 18 1.7e-05 0.0018 18.7 5.0 1 23 984 1007 984 1007 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.2	1.3e+02	3.4	0.1	2	23	269	291	268	291	0.92
2	18	0.037	4.1	8.2	0.5	6	23	300	317	299	317	0.99
3	18	0.022	2.4	8.9	5.6	1	23	323	345	323	345	0.98
4	18	7.6e-06	0.00083	19.8	1.6	1	23	353	375	353	375	0.99
5	18	1.3e-05	0.0015	19.0	0.3	2	23	382	404	381	404	0.95
6	18	2e-05	0.0021	18.5	0.4	3	23	412	432	411	432	0.96
7	18	0.0001	0.011	16.2	0.2	2	23	441	463	440	463	0.95
8	18	0.00069	0.075	13.6	0.1	1	23	470	493	470	493	0.94
9	18	0.0022	0.24	12.0	0.3	1	17	499	515	499	516	0.89
10	18	0.55	60	4.5	0.2	6	23	755	772	755	772	0.98
11	18	1.1e-05	0.0012	19.3	2.0	1	23	778	800	778	800	0.99
12	18	0.0079	0.86	10.3	6.4	1	23	808	830	808	830	0.98
13	18	2.5e-06	0.00028	21.3	0.3	1	23	838	861	838	861	0.96
14	18	0.0023	0.25	12.0	0.2	3	23	869	889	868	889	0.96
15	18	2.8e-05	0.003	18.0	0.8	2	23	898	920	897	920	0.97
16	18	0.00023	0.024	15.1	0.1	1	23	927	950	927	950	0.94
17	18	6.7e-07	7.3e-05	23.1	1.0	1	23	956	978	956	978	0.98
18	18	1.7e-05	0.0018	18.7	5.0	1	23	984	1007	984	1007	0.98

Sequence Information

Coding Sequence: ATGCTTTGTATATTATGTGTTGGGTCAACAGATAATTACATACACATATTTCAAGATGAGGGGTGTGCTCAAAACATCGAGGCAATTATTGTAAAACACTTTTGGTTGCAGCCAAATGTTAATGATGTGAATGCAAGAGTTATATGCACACCATGCTGGTGTGCATTGGAATCATTTCATAAATTCTACCTTCATATCGAACAAGCTCATGCAAGATTGCAAAGTGCAATTGAAAAGGGCGGTTTAAAACTGGAAAATGATAATATTGCGCCTCAACATATTCACCAGAATCCTGCTGCACCATTTGACGAAATTGCGACAGATTTTCTCAATGCAGATATTAAGCTCGAGGTACAAGAGGACATCGAAGTGAAACTCTTGCCAGAAGTTGCGACCGCTGAATCTGATAAAACGGAAGAATCATTTATTAAAAGGAAGCATTCCATAGAGTCAAAAAATTCAATTGAACATGATGCACCCCCTGCTAGCTCTACAAGAAGCCGAACCTCAGCAGAGAAGTCTTACACCGAATTGCAATCATCAAGTGACGAAGAGAGGGACAATGACAATACCGCAGAGTGGCAAAATCAAAACTCTGACAACGACGATGACGATAGTGATTATGTTGACAATTCATCCAGAACCAGTAAAGGTGCAGAATCTTTGTCGAAAAAACGCGGTCGACCAAAGAAAGGTGAATCGAGGGAGACACCTAGAAAGAGGAATCGCACGTCAGAGGAACAGTCCAAAAAGATGGAAAGAATTCAAGAATACGACGAGTTGATTGCGAAAAATATGAAATTGACGTGCTCTATTTGCTTAAATATATCTCCAAATTTCGCCGTCCTGAAAAAGCACTATCGTGTTATTCATAACGAATGCGGTTATGCCACATGTTGCGGGAAAAAGTTCCGAAAACGTGGCGTGCTCGTTGATCACATCTACACTCACCAAAATCCCGAATACTTCAAGTGCAAGAAATGTGGAAAAGTTCTCGCAAACAGGAAATGTCTGGATTGTCATATGTTAACGCATGACACGGAGAAACAGCGTATTTATCAATGCGATCAGTGTACAATGAGCTTCTACACACGACCATTACTTACAAGGCATTTGCAAACACATATTGCCGTTCGAAACATCAAATGTCCCGACTGCGATAAGTTTTTCTCAACGCAGGACATACTGCGAACACACATAAATAACGTTCATAATTCAGCGTACAATCGAATCTGCGATCAGTGTGGAAAACTGTTTCGTCGTCCAGATGCATTTCGTCGTCATCAATTAGAACATGATGGGATTACTCAGCCGCTAGTGCCATGTGAAAAATGCGGTGTAAAACTAACTAGCAAGTACGGTCTCAAGAGACACATGGAGTCAATGCATCCAGAAACTGAAGTCACACATGTGTGTACCACTTGCGGGAAGATTGCTCCATCTGCAGCGGCGCTGCAGAGACACATATCGTATATGCATAAAATGGAACGAAAATATAAATGTCCTATGTGTGACAAGGCGTTCAAAAAGACCGGCGGACTCAAGCAAGTGGAAGAGGCGCATGTTAATTTGGTGAGAACAAGCACCGCTGCTAGAGATGTGTTGAAACAAGAAAATGAGCAGATAGTCATTTCAACAGAACTAGAAGAAAGTAATAATTTCAACCCGGTGTCGGATTTTCTAACAGCAGACGTGAAGCTTGAAGTTAAAGACGATGGCGAGGTCAACTTGCAACAATATGATCCACTTCCCGACGTAGAGGAAAAAATTGACGTCAGTCAAATAACGACTGCAAAGCGTCAGAAATTGTCAGAATCATTGAATTCAGATGACTCTGAATCCGAAATCCCTCTAGCAAGCTTAGCCAAGACCCGTTCTAGGAAAACATCTAAAGTAAAACCAGCCGCGGTGTCTACTAACGATGAATCCGAATCGGGAGCAGAGTGGCAGGACAATAATACCGTTGATGACGATGAAGATGATGAAAGTGAATTTGAAGTGAAGAAAACACCAAAGCGAAAAACAGTTACAAACACAGGTAAAAAACGTGGTCGGCCATGTAAAAATGCTCCAAAGAACAATCCTCCCAAGCAGACAACTGAAGAACAGAACAAAAAGCGCGAGCTTTCTCAGGAATACGATGAGATTATCCACAAGAATATCAAATTAAATTGTAACCTCTGTCTACTGCCATTAGCAAATTTCTTCATCCTAAAGAAACACTATCGGTCCAAACACAACGAGCGTGGCTATGCTCTTTGTTGTGGGAAGAAATTCCTTAAGCGTGGAACTCTGGTCGATCACATATACACTCACTTAAATCCGGAGCATTTTAAGTGCGACAAGTGTGACAAGGTTTTGGCAAACAGACGATGTCTCGAAGTTCACATGAACACACATATAACAGAAAAACAACGCATCTACCAATGTGATCAATGCTGCAAAAGTTTCTTTAAAAAACCACTGTTGACTCGTCACATGCATGTTCATATACCCGAAGAGGAGCGGAAATTCCCGTGCGAGGAGTGCAACAAATTCTTCCCATCCAATTACACACTGCGAGCACATATCAATAACGTGCATCAAAACGTGTATGCAAAGATATGCGATCAGTGTGGGAAATCAATACGTGGTAGAGAGGCGTTCCAAAGGCATCTACTGGAACATGCTGGTATACCGATTCCCAGTGTTCAATGCGATAAATGTGGGGCAAAATTGAAAAACAAATATGGCCTTAAACGTCACATGAACTCAACGCACGCGGAATCAAGTGTTCCACACGTGTGCAACATTTGCGGAAAGATCGCACCTAATCCTGCTGCTTTGCAGCGTCATTACTCATATGTGCATAAGTGTGAACGTAACCACAAGTGCCCAATGTGCGATAAGGCCTTTAAAAAGGCAGGAGGACTTAAGgaacatatgacaacacataccggagaagttctctacacttgtccgcattgcccgaaaacattcaactctaacgccaacatgcattcgcatcgaaagaaaatgcatcgtaaagaatgggaggagAACAGACGGCATCCACACATGGGTTCCACTGCGAGTACAGAATAA
Protein Sequence: MLCILCVGSTDNYIHIFQDEGCAQNIEAIIVKHFWLQPNVNDVNARVICTPCWCALESFHKFYLHIEQAHARLQSAIEKGGLKLENDNIAPQHIHQNPAAPFDEIATDFLNADIKLEVQEDIEVKLLPEVATAESDKTEESFIKRKHSIESKNSIEHDAPPASSTRSRTSAEKSYTELQSSSDEERDNDNTAEWQNQNSDNDDDDSDYVDNSSRTSKGAESLSKKRGRPKKGESRETPRKRNRTSEEQSKKMERIQEYDELIAKNMKLTCSICLNISPNFAVLKKHYRVIHNECGYATCCGKKFRKRGVLVDHIYTHQNPEYFKCKKCGKVLANRKCLDCHMLTHDTEKQRIYQCDQCTMSFYTRPLLTRHLQTHIAVRNIKCPDCDKFFSTQDILRTHINNVHNSAYNRICDQCGKLFRRPDAFRRHQLEHDGITQPLVPCEKCGVKLTSKYGLKRHMESMHPETEVTHVCTTCGKIAPSAAALQRHISYMHKMERKYKCPMCDKAFKKTGGLKQVEEAHVNLVRTSTAARDVLKQENEQIVISTELEESNNFNPVSDFLTADVKLEVKDDGEVNLQQYDPLPDVEEKIDVSQITTAKRQKLSESLNSDDSESEIPLASLAKTRSRKTSKVKPAAVSTNDESESGAEWQDNNTVDDDEDDESEFEVKKTPKRKTVTNTGKKRGRPCKNAPKNNPPKQTTEEQNKKRELSQEYDEIIHKNIKLNCNLCLLPLANFFILKKHYRSKHNERGYALCCGKKFLKRGTLVDHIYTHLNPEHFKCDKCDKVLANRRCLEVHMNTHITEKQRIYQCDQCCKSFFKKPLLTRHMHVHIPEEERKFPCEECNKFFPSNYTLRAHINNVHQNVYAKICDQCGKSIRGREAFQRHLLEHAGIPIPSVQCDKCGAKLKNKYGLKRHMNSTHAESSVPHVCNICGKIAPNPAALQRHYSYVHKCERNHKCPMCDKAFKKAGGLKEHMTTHTGEVLYTCPHCPKTFNSNANMHSHRKKMHRKEWEENRRHPHMGSTASTE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00672341;
90% Identity: -
80% Identity: -