Elan017679.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eriosoma lanigerum
Gene Symbol
RAP1GAP
Assembly
GCA_013282895.1
Location
scaffold:47479126-47486256[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 4.6e-05 0.024 15.4 0.0 5 43 509 550 506 562 0.91
2 2 1.7e-09 9.2e-07 29.6 0.0 49 109 684 744 676 745 0.92

Sequence Information

Coding Sequence
ATGATCAAATTCACCAGATTAAAAATAGAAATCTACCTGCACCTTGATGATATATGTGATGAATGGTCACATAACTTCCAGCCAGCTCCTGGTTATTGGATAGAATGTTCTCGTCAAAAAATCACAAGTGAAGCAGGATGCGTTGAAGAATCTGGATCCGATGAACGAGAATTAAATAACGGTTCAAATTCAGATGGTGCTGATGGTGCTCAAGAATACTTTGGAAATAAGTATGGCAGGCCCAGAGGTTCCGACAGTCTTCTACTAGAGGATGATGAATACTATCCATATGATGATGATTATGTTATGCCACCATCCAGACCAAAAACATCTATTGAAGAACAATGGGAGAAAAATCGATGTTTTGAACTAACTTCTGTAGAACAAGAGACATTTGAAAGGTATTTCTATCAAAAAGAACACTGGAATTACTTTACAAATGACGAAGATTTGGGTCCAATTATTTTGAGTCTTAAACAGGAAACCATAAATGGCCGAGATCAATTTAGGATATTAGTCAGAGCAATCAGCTACACGGTACATGGCTTAATACCGGCTTCGTGTGTGTTTGCCGATCGCTATAACCGTGAGGAAGTGGTGAGATCATTAGGTAAAGAGATAAATTTAAATCCACCATTAGTACTTGGTCAACTACCTGACACAGCCGATGAACTACTCAAATTAGACCAAGTTTTCATGAAATCTGAACTTAAAGTTGGAGTAATATATGTTAAAGAAGGCCAAACAACTGAGGAAGAAATATTGGATAACAATGAAAATAGCTTAGCATTCGAAGATTTTCTTGGACTATTAGGAGAGACCAAAAGACTTTGTGGTTTTGATAAATATCGAGGTGGATTAGACACGGTACACGATTTGACTGGAACCCATTCTGTTTACACTAATTGGAGAAATATTGAAATCATGTTCCACGTGTCTACTATGTTACCTTATGAAGCACATGATGCACAAAAACTCCAACGAAAAAGACATATTGGTAATGATATTGTATGTGTTGTATTTCTCGAAGCTGACGAGACTAAATTTTCACCTGCCTGCATAAAATCTCATTTTCTTCATACTTTTATACTGGTCAGAGTAAGCCCAAGAATAAGAAGAAAAACAGAAAGGACTAAATATGAAGTTTCTGTCGTTACCAGAGATGAAGTAGGGGCATATAAACCATATCTTTGGGAACAATCAGTTTTCGAAGAAAAGGATATGTTTAGAGAATGGATTTTAACAAAAATCGTAAATGGTGAAAGAGCTAGTTATTCAGCGCCTAAATTTGCTAGAATGCAAGAACGAACTCGTAGTCAAATGCTTGAAGATATTGTTGCAAACTTACAAAATCATTGTGAGACTGGACAAATACCTAAACCTTATAGGAGAGGTTCGTGGAGACCAATTGGGCATATGAGGCCATCAAGTCCATTACTAGATTCAGTTAGAGATCGATTTGAAGACTATGACACTCTAGCAAAAGACTTTACAAAATTCTTTATCAACTCTGAATTAAATGTCTCCCAAAATGGTCATTTATTTGATGTTGTATTTTTAGTGGGCCAAAGTAAGCAAAAGACAAGGTTTATTGGTGTGAGAGCAATTTTGGGTGTAAGAAGTCGAGTATTCCAAGAAATGTTATACGGAATATCTACGGGTTTTGGATCTCCTCAAATGCCAGTTGCTGAATTATTAGCTCGAGGACTTCCAAGTTTACCCTCTCAACAACATCAAAAAGCAAAAAGTAGTAACTTTTTACAAGTTCCTGATATAGAAACACCTAGGGCTAAAAGTGTTCCAAGTTCTCCTATGATGCGAAGAGCATTTACCAGATTAGGAACAATTACTGCCGGATGGAGTAAATCTATAAGAAAACAACAAAACCTGTCAGCTGATGATAAAAAGAAATGGGCTTCTTCTCAAGATTTCAGTCATAAAGAAAAAGAGAAAGATAAAGAAAAAGAAAAAGATAGGTTAGCTCAGTTGTCTGTACCTAAAGTCAGTGTTTGTCCAAATAATGGTGGAGATAAAATTGATCGAGCAAAACTTAATCAAACAGAGTTTTCCATAATTGAATTTGATCCTGACACATTTCGAATATTACTGGATTACTTGCATACAAGCTCTTGTAAAATTACATGTGCTAATGTTCCTGGATTAATATGCGCTGCGGAACACTATGATTTGCCAGAACTCTTACAGGCATGTTTTCATCATACAAAGCAACATTTAAGGGTAGATGTGGTTTTAAATCATTGTGATTTTCTCACACTTTCCGAATCCCTGGTACAACAGATTATGTGCAGGCCACTCGAAGTGTCAGAAATTCGTAAATTCCAAGCAATGATAAAATGGGCAACTAATAAAAGTCAGTCAAAAACGAACGCTAAAGAAGAATTTCATCATATAATGACGAGACTTAAAAAAGATATTAATTTGGTGAAAATCGCACCCAACGATCTCATAAACATCGTGTTACCAACACGAACTGTCGATAACCAAGACATTCTAAGCACCCTATGCAAACAAGCTGGCACCGGGGAGTACAAAATCGAAAAGACTGTATTCGAGAGGCTTAGCAGACATAGGTCTGATTGGGACCACGTCGAGCCTTACTTATAA
Protein Sequence
MIKFTRLKIEIYLHLDDICDEWSHNFQPAPGYWIECSRQKITSEAGCVEESGSDERELNNGSNSDGADGAQEYFGNKYGRPRGSDSLLLEDDEYYPYDDDYVMPPSRPKTSIEEQWEKNRCFELTSVEQETFERYFYQKEHWNYFTNDEDLGPIILSLKQETINGRDQFRILVRAISYTVHGLIPASCVFADRYNREEVVRSLGKEINLNPPLVLGQLPDTADELLKLDQVFMKSELKVGVIYVKEGQTTEEEILDNNENSLAFEDFLGLLGETKRLCGFDKYRGGLDTVHDLTGTHSVYTNWRNIEIMFHVSTMLPYEAHDAQKLQRKRHIGNDIVCVVFLEADETKFSPACIKSHFLHTFILVRVSPRIRRKTERTKYEVSVVTRDEVGAYKPYLWEQSVFEEKDMFREWILTKIVNGERASYSAPKFARMQERTRSQMLEDIVANLQNHCETGQIPKPYRRGSWRPIGHMRPSSPLLDSVRDRFEDYDTLAKDFTKFFINSELNVSQNGHLFDVVFLVGQSKQKTRFIGVRAILGVRSRVFQEMLYGISTGFGSPQMPVAELLARGLPSLPSQQHQKAKSSNFLQVPDIETPRAKSVPSSPMMRRAFTRLGTITAGWSKSIRKQQNLSADDKKKWASSQDFSHKEKEKDKEKEKDRLAQLSVPKVSVCPNNGGDKIDRAKLNQTEFSIIEFDPDTFRILLDYLHTSSCKITCANVPGLICAAEHYDLPELLQACFHHTKQHLRVDVVLNHCDFLTLSESLVQQIMCRPLEVSEIRKFQAMIKWATNKSQSKTNAKEEFHHIMTRLKKDINLVKIAPNDLINIVLPTRTVDNQDILSTLCKQAGTGEYKIEKTVFERLSRHRSDWDHVEPYL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00463475;
90% Identity
iTF_00184754; iTF_01499793; iTF_00463475; iTF_01167810; iTF_01304995; iTF_01170020; iTF_01347366; iTF_00308969; iTF_00134634; iTF_00941810; iTF_01330738; iTF_01033142; iTF_00469079; iTF_01434199; iTF_00136281; iTF_01032286; iTF_00340735; iTF_00418424; iTF_01038556;
80% Identity
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