Basic Information

Insect: Eriosoma lanigerum
Gene Symbol: egg_2
Assembly: GCA_013282895.1
Location: scaffold:14880240-14896838[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 8.7e-10 4.8e-06 26.7 0.0 6 71 588 648 583 654 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	8.7e-10	4.8e-06	26.7	0.0	6	71	588	648	583	654	0.84

Sequence Information

Coding Sequence: ATGCAAATTGTGCACGTCATTACATCCACCCCAGACTTTTTTTTGTTGTGCCCTCACAACAGTGACCGTGGTCAATTTTGGAGCAATGGAAGAACGGTTGAGTGTGAAGGGATGAAATTAATTTGTTATGTTTTAAATTTGGAAATGGAAAATTCAGCTTTAGTATTAATAAATAACCCCCTTCAACAAGTAAAATGCATTAACCAATGTTGCCAATCTGACAATACTGGCCTAACTGAAGCAAATCAAATTGTGTGCGATTACTATAACGTCGAATACATACGAAATAAGATGGTTTGTTCATCGTGTTTAAGTACATGTTTAAAGTATTATAGAGGTCTGAATGATAAATTTAAAGCTGGGGAATGTATTATGGATACTAGTCCAATTTATAAACCACATAAAGAAGGGGAAGATGAAGAGAAAGAGAAAGAAGACTCGAATGTTAAAAATTTTGATTTTGCCAATGAACATGTCCATGCTTATAATGTTATGTTTGATAATGCTATTAAACAACATGGACATCTTCTAAATAGTCAATTTTCATTATGTACTGAATATATAGATAACAAAATAAAGACATTAGATTCTGAATTTACTAAATTTGATGAATTTATCAATAAATTACAAAATTGCATTTCAGTAATGAAACAAAATGTTTGCATAACAGCAAATAAACAAACATTACCTCAACCTTCTGTTATAAAACCAAATAGAAAGATAAATAAAATACCATTAACTAACAGTCAATCTATTTCTATATTACATTTAGAACCTGACAGGGGGATACAAGAATATCCTCCTCTTCATATTGGACAAGTGATGTATGGGATGTCATTAACTACACTACATCCATGGTATAGGTGCAAAATTATTAAAATTTGTAAAAATACTCTACTTTTAAATTTTGGTTCTTGTAAAAAAATATTGACAAAACAACATGTTGCGTTCTCTTCTAATAGTCCAGTAGAATTCATAGTCGGTTCCAGAATAATTTCGAAATTCAAAGATTTGAATTCTAATATACCTGAACAATATTATGCTGGAATAATAGCTGAACCACCAATATCACTTAATAAATTTCGATACTTGATATTTTTTGACAATGGATTATCTCAATACCAAGATCATTCAAATATCCATTTAGTAGTGCGCAATTTAAAATACGTATGGGATGATGTACATCTAGAAAGCAGAGAATATATAAAATATTATTTAAAATCCTATCCCGAAAGATTTATGAAGATATTCATCAAAGACACCTATGTTGAGGTTCTGTATCAAAGTGTGTGGCTTTCAGCGAAGGTAATTGACGTGGATGCTTCTTTGGTAAAAATATATTTTGAAACACAAAATCGATATGAATTGTTATATCGTGGTTCTCCAAGATTTAAAATTAATATTGGGAAAAACAGTCATTTCGGGAATTACGTTCACGTTATAAAATCTCCGCAGGATTTAGAAATAAGTCAATCGAATAAGTCAATCATGAGTCGCACAAATTCAAAGGAAAAACCCTCGGTCAAAAAGTCGAGAAACGTATCTCGTAAAAGTACAGCAAACAAAATAGCGATAAATAGGAATCAGCACAAATACACAACAACCAATCTAGCAACAACATCAACCGCACTAGTTGAAATGAATGACAACAATCGCTTGTTGTCATTGTCAAATAATAATGATATGGATAGTGAATACAAATGTAATCGATTTTGTATAGATAAGATTGCATATGATTATAGCAAAACGAAAATGTTAAACTCATTGGCTGTGCCGTTGAGTTTTGGTTATAGAAGACGTATTAAGGAGTGCATTAAATCGAATACGAATACTGTTATATACAAAACTCCATGCGGCCGTATCATCGATAATATTAGCGAAATGCATAGTTATCTTATATCCACCGAGAGCAAGATGACGATTGATCAATTCTCTTTTGATACCTTTTTAAACCCAAAAAGAGTGTTCAAAATTATCAAATCCTTAATATTGATCAAAGATATATCGGATGGCCAAGAATTCAAACCGATATCATGTGTGAACAGTGTTAACAACCTGTTGCCTCAACCAATGAATTATTTGATCAGCAGACAACCTATGTTGGACGTTAGCCTAAACGTTGATAGCGATTTCCTGTGCGGATGTGATTGCACAGATAATTGTGCTGACAAATTGAAGTGCGCTTGTTGGCAGATGACAAGAGACGCGCAAAAGGTTTTGCCTGACTTGTACAACTATGAGAATATCGGATACAATTATCGGCGTTTATCCGAGGGCGTCATAACGGGAATATACGAGTGCAACAAATTGTGTAAGTGTTCGAGCTCGTGTTTGAATCGCGTTGTTCAGCAACCGATTACACAGAAGTTACAGCTGTTCATGACGGAGAAGAAGGGATGGGGCGTACGTTGCTTAAATGATATACCCAAAGGTAGTTTCATATGTTGTTACGTTGGAAATTTGTTAACCGAGACGGAAGCTCTCAAGGGTGGTAAGATCTACGGCGATCAATATCTAGCTGATCTGGATCTTATCGAAACGGTCGAAAAGATGAAACGTGGTTACGAAAGTGACGTGTACGAGAGTGACCAGGAAAATAGTGAGACCATGAATGTAAGCGACAAGTTTACAAACTTATCCGATTCCTCAGACGACGAATTTCGTCTCACAAAGTATAACAGTGATGTGATAAAAAAAATTGGAGTCGTCGAGGACTTTACGTCACGGTTGCGCAAACGGCGAAAGGCACACAATAATGACAAGTCGAAGAAACATTGTAACGGTAACGCGTCTTCGAATTCAATGCGCAGATTTTATGGCAAAGGTGAAGACATCATGTACATGCTAGATGCGTGGACGAGCGGAAACATTGGGCGCTATTTAAACCACTCGTGTTCGCCAAACATGTTCGTGCAAAACGTGTTTGTGGATACGCATGACTTACGGTTCCCGTGGGTAACGTTTTTTGCACTACAAAATATACTTGCCGGTACTGAACTGACTTGGGATTATCGTTACGTCGTAGACAGCGTACCTGGTAAAGTGATGCAATGCCATTGCGAAGCATCAAACTGCAGAGGTACTTACATACCAAGTCGATCATCGATAGTCTGTGATAACGGTTCTTATGCTTTAAAAGCTGGCTTTGCGGGAGATGATTTTCCCCGAGCAATTGTTCCAAACATTGTCGGGACACCGCGAAAAGAAATGAATATACCAGGATATGGACAAAGAGTCACATATGCTGGCCAGTTTGCTAAAGAAAATCAAGGTATCTTCGATATAACTTGTCCAGTACGTAACGGAATAATTTATGATTGGGATGCTATGGAACAAATTTGGTATCATATGTATTACGAGGACTTGGTAGTGCCACCAGAAAACTTTAACATTTTACATACTGAACCGGTTAACAATCCTAAGTCGTGTCGAGAAAAAATCACCGAGATCATGTTTGAATTATTCAACGTGCCCAGCACCGCGCTGGTGCCGAAGTCCGTTCTGCCGTTGTACAGCAACGGCAAGACCACCGGGATAGTGGTAGACTCCGGACACGACGATACGCAAGTCGTGCCGATCTACGAAGGATATCCGTTACAATACGCGGTTAGAAGCATGCCGGTGGGCGGATGGCACGTGACGCGTTATCTGATGCAATTGTTGAACGACCGCGGGTACACGTTCACCACGATGAAGGACTGGGATCACGCGCAGAACATCAAAGAAAAGTTTTGCCACACCGCGTTGGATTTCGACAAAGAACTGGCTATGTTCACCAGGAACATGGAACAAAATTATACGCTGCCCGACGGATTGGTGGTCAAAATCAACAGCGAAACATTTCGATCAACTGAAATTTTATTTGATCCGACTTTGTTCAATATTGAATCTGAATTAGGAGGTATCCATGATATATTATACGCCGCTTGCAATGCTTGCAATGTTAAGGAACAATCGAATATGTTTAACAACATCGTGTTGGCTGGTGGTAATTCATTATTTCGGTTACTATCTGAACGTATAGAAATTATGTTGTCAAAATTAGTTTTATCTACAACCACAATTGCAATTAACGCGACTCCCGAACGAAAGTACTCTACGTGGATCGGTGGTTCGATTTTAGCTTCGGTACCCACTTTCGAGCAAATGTGGATTAAAAAACAGGAATACGAAGAAAATGGACCTAACTTTGTGCACCAAAAATGTTTTAGTTAA
Protein Sequence: MQIVHVITSTPDFFLLCPHNSDRGQFWSNGRTVECEGMKLICYVLNLEMENSALVLINNPLQQVKCINQCCQSDNTGLTEANQIVCDYYNVEYIRNKMVCSSCLSTCLKYYRGLNDKFKAGECIMDTSPIYKPHKEGEDEEKEKEDSNVKNFDFANEHVHAYNVMFDNAIKQHGHLLNSQFSLCTEYIDNKIKTLDSEFTKFDEFINKLQNCISVMKQNVCITANKQTLPQPSVIKPNRKINKIPLTNSQSISILHLEPDRGIQEYPPLHIGQVMYGMSLTTLHPWYRCKIIKICKNTLLLNFGSCKKILTKQHVAFSSNSPVEFIVGSRIISKFKDLNSNIPEQYYAGIIAEPPISLNKFRYLIFFDNGLSQYQDHSNIHLVVRNLKYVWDDVHLESREYIKYYLKSYPERFMKIFIKDTYVEVLYQSVWLSAKVIDVDASLVKIYFETQNRYELLYRGSPRFKINIGKNSHFGNYVHVIKSPQDLEISQSNKSIMSRTNSKEKPSVKKSRNVSRKSTANKIAINRNQHKYTTTNLATTSTALVEMNDNNRLLSLSNNNDMDSEYKCNRFCIDKIAYDYSKTKMLNSLAVPLSFGYRRRIKECIKSNTNTVIYKTPCGRIIDNISEMHSYLISTESKMTIDQFSFDTFLNPKRVFKIIKSLILIKDISDGQEFKPISCVNSVNNLLPQPMNYLISRQPMLDVSLNVDSDFLCGCDCTDNCADKLKCACWQMTRDAQKVLPDLYNYENIGYNYRRLSEGVITGIYECNKLCKCSSSCLNRVVQQPITQKLQLFMTEKKGWGVRCLNDIPKGSFICCYVGNLLTETEALKGGKIYGDQYLADLDLIETVEKMKRGYESDVYESDQENSETMNVSDKFTNLSDSSDDEFRLTKYNSDVIKKIGVVEDFTSRLRKRRKAHNNDKSKKHCNGNASSNSMRRFYGKGEDIMYMLDAWTSGNIGRYLNHSCSPNMFVQNVFVDTHDLRFPWVTFFALQNILAGTELTWDYRYVVDSVPGKVMQCHCEASNCRGTYIPSRSSIVCDNGSYALKAGFAGDDFPRAIVPNIVGTPRKEMNIPGYGQRVTYAGQFAKENQGIFDITCPVRNGIIYDWDAMEQIWYHMYYEDLVVPPENFNILHTEPVNNPKSCREKITEIMFELFNVPSTALVPKSVLPLYSNGKTTGIVVDSGHDDTQVVPIYEGYPLQYAVRSMPVGGWHVTRYLMQLLNDRGYTFTTMKDWDHAQNIKEKFCHTALDFDKELAMFTRNMEQNYTLPDGLVVKINSETFRSTEILFDPTLFNIESELGGIHDILYAACNACNVKEQSNMFNNIVLAGGNSLFRLLSERIEIMLSKLVLSTTTIAINATPERKYSTWIGGSILASVPTFEQMWIKKQEYEENGPNFVHQKCFS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -