Basic Information

Gene Symbol
-
Assembly
GCA_905404285.1
Location
FR990071.1:14843803-14855854[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 0.01 0.92 10.7 0.9 3 23 209 230 208 230 0.90
2 24 1.4 1.2e+02 4.0 0.1 6 23 596 615 596 615 0.90
3 24 0.028 2.4 9.4 0.3 1 21 620 640 620 641 0.96
4 24 4.7 4.1e+02 2.4 0.2 1 23 682 705 682 705 0.89
5 24 0.0002 0.018 16.1 1.6 3 22 716 735 716 735 0.96
6 24 0.84 74 4.7 0.1 3 23 744 765 742 765 0.94
7 24 0.14 13 7.1 0.6 3 23 786 807 784 807 0.95
8 24 0.0021 0.19 12.9 1.3 1 23 813 836 813 836 0.92
9 24 0.094 8.3 7.7 0.0 1 23 862 885 862 885 0.90
10 24 0.0041 0.36 12.0 3.5 1 23 890 912 890 912 0.97
11 24 0.0057 0.5 11.6 0.2 1 23 918 941 918 941 0.95
12 24 0.0023 0.2 12.8 1.5 1 23 949 971 949 971 0.97
13 24 0.00013 0.012 16.7 1.8 1 23 1020 1043 1020 1043 0.97
14 24 0.003 0.26 12.5 1.2 1 23 1100 1123 1100 1123 0.96
15 24 0.00083 0.073 14.2 2.1 2 23 1150 1172 1149 1172 0.95
16 24 0.22 19 6.6 0.1 3 23 1179 1200 1178 1200 0.94
17 24 0.0095 0.84 10.9 0.2 1 21 1244 1264 1244 1265 0.95
18 24 0.00092 0.081 14.0 0.6 1 23 1275 1297 1275 1297 0.93
19 24 8.4e-05 0.0074 17.3 0.3 2 23 1392 1414 1392 1414 0.93
20 24 5.7e-07 5e-05 24.1 1.3 3 23 1421 1441 1420 1441 0.98
21 24 0.0057 0.5 11.6 0.7 1 23 1458 1481 1458 1481 0.94
22 24 0.16 14 7.0 0.0 1 23 1502 1524 1502 1524 0.98
23 24 0.021 1.8 9.8 0.6 1 23 1530 1553 1530 1553 0.95
24 24 0.00019 0.017 16.2 0.4 1 23 1561 1584 1561 1584 0.96

Sequence Information

Coding Sequence
ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAAGCGAATTACTGCCGATTTTTCCTACCACCAGTTCAGATGACACGGAACCTCCCGTCCTCGTCACGAAAATCAAGGATTGCGTGTCGGTCCAGATAAACGAAAATGACGAACTGCCGACGAATGTCTGCAGGAAATGCATGGACAATGTCAATAACTGGCATATATTCAAGTCTGTTTGTGAAAAGACACAAAACAAACTACAGTCTCTGATTAAAAAGGATGGCAGCCTACTAGAAGAGGTGAAAATAAAGAGTGAGCCATTTTATGATGAGGCTTATGATGATGGAGTGGTCATTGATGGATCCTACCCAGTCATTGAGAATGTCGCCTCAGCCAGCAAGCTTCAGCCTGAAGGTCCACCGATTCTGGCTTCCCTGGGACTCACACCAAGGAGCGATAAGGGGGTGGAAAGCGAGAATAACGAAGAGGACGACTACGAGGAAGAGACGAATGAGCCGGAGCCCCCACAACCTTTAAAAGTCCCGAACATGCCCGAAGTATCCATCACAGTAATGCGTAATACTGGAGAAACCCTCCACGCGAGGCAAGGCATACAACAACTCGCTTCCAAGGACTGTCTTATTTGCGGACGCACTTATAGGTACTCCCACAATGCTCGCAGGCACGAACTGGCGTCTCACAGCTTCGATCGCTACACAAATAAAGTTACAAACAAAAAGTCGCATCATTCCCGTATGATGCCCAAACTCAGACCCAACCCCTTCAATCCAAAATCCCGTCTGATGCCCAACCCAATCAGCCACAAATTGCAATTTATGCCCAAAAGTATTCCCACCAAAATATTACCGCGAAAAATCAACCCCCCACCGAAACCGATACCAATCAAAACGCTTAAGGCATCTACAAATAATCTACCATATCCCTTGCGCATAAAAGCGCTCAAAGACTTGCAGATAAAGAAGAAAGAACCGCAGATTTTGAAGACCTTGCTCACCGCGAAACCCGAGGTTTTAGTGTCGGAGCCGGAAATAATGAACTCCGGTCCGGAGAGTCCAGAAACGCTGATATCGGAGCCAGAGATCGCGTCTTTTCAGGTAGAAGCTATTCTATCCGAACCTAATGAATACGATCAAAATCAAGACGAGGAAGGTGAAATGGATCACGAAAATCAGACCCAAAATTACGACACTGTCGATATGGAATCCGATCATGAGATTGAGATCGCTCGTCAACAAGAAAACGGGGCCGAAGACGAGGACAAGAATGAATTTGTTGAAAATAGCGACGAGAATATGCATCAAGATCAAGATCCAGATAATCATATGGACGAGAATGAAAAACATGTTGAGAGTGATAATGAAGGAGATCAGGACACTGTTGACAGCCAGGGAAATATGGAGATAGACGAAAGCTGCAACCATGCGAACATCAATGACTTGGCCAAGTTAGACAAAGATGGGAACGAAGAAGGTGGCGAACCTGACGGGGTTGATCCTGATGAAATTAACCCTGAGGCTGATGATAATGATGGCGATGATGGCGAAGACATGCCGCCGCCTCCAGTCGTAGAACTAAATGAGGAAGTACAGCATTCGTCCAGCGAAATGAATGAGGACGAGGAAGAACTCGATGAAACGGGTGATCTCAACGAAACTATCGAACACAAATCGACAGACCTCGACCCAGACAAGACATACGTCACTAAAGCTCAAAAGGATTTCATCGAAAAATACCGTGACATCATTCAACAGATTAATACGAAACGTTGCATCTGCTGCGATAAAACGTACCCACGTAGGAAGGCAGTCGTCCAACATTTGCAGAAAAATGGACACAAAGTCCCCAAACATACATGCTATAACTGCGTGATAACGTTCACTCATATCGGAGCGCTGCTCAGTCACATGAGAGCGAACGCTTGTACGGATCTATGGAAAATCGTTTTCGATAAAAACGGTATTCCCGATGAAATGGTTATCAAATACGAACCTCAGGTCAAGATTCAACCTAAAGATATTTTCAACGCTCGTTCGTATGCGTGCAGACTTTGCCCGGCCAAGTTCCAGCTGAAGCAATCCATAATGAAGCATGTGTTAGATGTGCATGAAGACGGCCAGTCTAATATTCCGCTCGGCTGTGTTCATTGCCGGACCAGCTTCAAAGACAAATCTCTACTCAAGAAACATATTCGCGTCGGCGAATGCACGGTTTACATCAATTGTGATTTATGTTCGGAACAATATTCGAATATGCAAGACTTCAGCGACCACGCTCTGACGGTCCACGCTGACCACTTCGAGAAGTCTGACAACCAAAACAAATGTATCGATGGTCGCGCCACCGACTGTTCCCTCTGTGGGAAAAAGAACAGCAACTATTTGAATCTTGTGAAACATTTGAAGTTGGTTCACAATGAAGATAGGCCTCATTACTGTCAGAATTGCGATGCTAAATTTGAGCATGCTGCTGACTTGAATAAACACATTTATGCTGAGCATTCTGACCAAGCATTGGGGTTGACGCCTCAGGAGCCGGATATGACTCTCGTGAAAGAGGAAGCCGAAGAATACCATTATTCGTGCACAGAATGTAACGCGATATTCGAAACTGTCGACGCTTGGACGGACCACCAAGTGGCGGAGCACAATCAAGTCGCCCATCACTGCGACCAGTGCGACAAAAAGTTCTTGCGACCGTCTGAGCTCGCCGAACACAAAAATACCCACTTGAGAGTCAAGTTCTACTCTTGCAGTGTTTGCCCGAATTCGTACAGTACTCCTCAAAAGTTGTCTGACCACGTCCAACAAGCTCATCCGATCGGAGGCGAAACAGAATTCTTCTGCGACGTTTGCATTCGATCGTTCAAAAGTCGTCAGGCCTTCTCGAATCACATGCGTATTCACGCTAAAGTGCCGACTACTAATAGGAAGCCGGGCGAACAGAAAGGATTCGATCCTCGCATTATCGGCAAACCAGTGAAACAGTTCACTATGGTCCAACCCGGTTTCGTCAACTTCAAGCCAAATGCTAACGTTCCTAATGCACCTTACTCGTGTGACATATGTGGTAAGGGCTTCATGCATAAGAAGAACATATGGAAACACAAAAAAGTGTTGCACGCGGACATTATTAACGATAGGAACGATAGCGAGGAGAATACCATGCATGCTTCCACGGAAGATGACGATTACAACCCTGAAGAAAACGGAGCTCTTTCTACCCCTCAATTCGATAGCTTTAACTTTTCCAATTTCAATAACAGCACACCTCAGCCAGACGCCATGCCGTTTTCTTGCGATCTATGTTCTAAGAGATTCCCGATTAGAACTAGTCTGTGGAAGCACAAACGCGCTAAACACGGGATCGTAAACCCGGGTGCCGGCGCTGGAGTCGATATGCTTGCAACACCAAAGGCGTCTGGGGAATCAAGTCGGTCCAGCTGCACCATTTGCAAAATAACATTTTCAGACAAGAAATCTTACTATCGCCACAGGAAGAACGTTCACAAAACGGCCACTGAGATGTGCAAGCTTTGCGGTAAACCGCTTAATTCAACACTGGAACTGTACGAGCATCTAAAGGCAGCACATGCCCGAGAATTGCTCGGATATAACGCTAATCAAGGCTCGACCAAAACGCAGGAAGTGTCTCAAGATCAAGATGGCGATTACGAAAACGAGCCGGAGTCTGCAGACCCCAGCATGGACTATCAGGCTCGATACCCTTGCGATACGTGTGGAAAACAGTTCGTTGGTTTACTGGCGTTGCAAAACCACCAGTGTCTTATTCAGCTACCGCAGCAACCGCAGACCTTCGATTGTGAAATCTGTCATAAGAGCTACACGTCAATCGCCGCATTGAAGAGTCACCGCGGTTGGCACCTACGCTCCCCGGACGGCAAGGCGGCTGCCAACAACAGCGGGCTCTGGATGCCGCAACATAAAGTGACGAGCAAGGTTAGCAAACACGAGGTTGTAGACGCGGTGCAGTTGGCGCGCGTTTCGCACTCGACCTCCGCCTCGCACTCGGCGCCCGCCGCGGCCGTCACGGCTAAAAGGAGACTGCCACCAGAAGTGGAAGTCACGGTCGTCAATCCTAACAAAAAGTTGCGCTCCGATGACTCGGTCGAGTTGGATCAGCAGAACGAAGCGGTGGACGGCCGATACTGCACCATCTGCGACAAAGAGTTCACGAAACGCGCCGCCTACCAGCGTCATATGGACGAGGTCCATCAACCGAATTCTGTGTTCTGTCCGGTCTGCGACAGAAGTTTCACCAGGAAGTCGACGCTTCTCGTGCACATGAAGAAGCATTACGAGACTGGCGAGGGCACGTCTACAGCGCAGGCGGAGGACGACGGCCACAACTGTGACGTCTGCGGCGCTGGGTTCGAAAGCGAGAAGGCGTTGAAGGCTCACCACGCGAGGTATCACGCGGAGGACTCGGGCGAGTCCGACGACGAGGGCAGCGTCCCCGCGGCGCTGCCGGGAGAGTTCACGTGTGGCCAGTGCGGCGACGGTGTTGCCAGCCCGCGCGATCTGTTAGCCCATCGCTCGATGCACGCCACTCCTACCAAATTTTTCTGCAATATTTGCAAGGTGTACTTCGCTCGAGCGCTGGATCTATCGTCCCACACTCGTGCGAGACATGCGGACAACGAAAAAGTTTTTTTCCCCTGTGCCATGTGTGACCGCTTCTATATGAACAAGAAGAGCTTACAGCGGCACATTGAGATGGCGCATTGA
Protein Sequence
MNVNYDRVCRLCLSSRSELLPIFPTTSSDDTEPPVLVTKIKDCVSVQINENDELPTNVCRKCMDNVNNWHIFKSVCEKTQNKLQSLIKKDGSLLEEVKIKSEPFYDEAYDDGVVIDGSYPVIENVASASKLQPEGPPILASLGLTPRSDKGVESENNEEDDYEEETNEPEPPQPLKVPNMPEVSITVMRNTGETLHARQGIQQLASKDCLICGRTYRYSHNARRHELASHSFDRYTNKVTNKKSHHSRMMPKLRPNPFNPKSRLMPNPISHKLQFMPKSIPTKILPRKINPPPKPIPIKTLKASTNNLPYPLRIKALKDLQIKKKEPQILKTLLTAKPEVLVSEPEIMNSGPESPETLISEPEIASFQVEAILSEPNEYDQNQDEEGEMDHENQTQNYDTVDMESDHEIEIARQQENGAEDEDKNEFVENSDENMHQDQDPDNHMDENEKHVESDNEGDQDTVDSQGNMEIDESCNHANINDLAKLDKDGNEEGGEPDGVDPDEINPEADDNDGDDGEDMPPPPVVELNEEVQHSSSEMNEDEEELDETGDLNETIEHKSTDLDPDKTYVTKAQKDFIEKYRDIIQQINTKRCICCDKTYPRRKAVVQHLQKNGHKVPKHTCYNCVITFTHIGALLSHMRANACTDLWKIVFDKNGIPDEMVIKYEPQVKIQPKDIFNARSYACRLCPAKFQLKQSIMKHVLDVHEDGQSNIPLGCVHCRTSFKDKSLLKKHIRVGECTVYINCDLCSEQYSNMQDFSDHALTVHADHFEKSDNQNKCIDGRATDCSLCGKKNSNYLNLVKHLKLVHNEDRPHYCQNCDAKFEHAADLNKHIYAEHSDQALGLTPQEPDMTLVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCDKKFLRPSELAEHKNTHLRVKFYSCSVCPNSYSTPQKLSDHVQQAHPIGGETEFFCDVCIRSFKSRQAFSNHMRIHAKVPTTNRKPGEQKGFDPRIIGKPVKQFTMVQPGFVNFKPNANVPNAPYSCDICGKGFMHKKNIWKHKKVLHADIINDRNDSEENTMHASTEDDDYNPEENGALSTPQFDSFNFSNFNNSTPQPDAMPFSCDLCSKRFPIRTSLWKHKRAKHGIVNPGAGAGVDMLATPKASGESSRSSCTICKITFSDKKSYYRHRKNVHKTATEMCKLCGKPLNSTLELYEHLKAAHARELLGYNANQGSTKTQEVSQDQDGDYENEPESADPSMDYQARYPCDTCGKQFVGLLALQNHQCLIQLPQQPQTFDCEICHKSYTSIAALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKVSKHEVVDAVQLARVSHSTSASHSAPAAAVTAKRRLPPEVEVTVVNPNKKLRSDDSVELDQQNEAVDGRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDRSFTRKSTLLVHMKKHYETGEGTSTAQAEDDGHNCDVCGAGFESEKALKAHHARYHAEDSGESDDEGSVPAALPGEFTCGQCGDGVASPRDLLAHRSMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
iTF_00207177;
80% Identity
-