Basic Information

Insect: Epinotia nisella
Gene Symbol: -
Assembly: GCA_932294385.1
Location: CAKOAM010000055.1:7898782-7915498[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.3e-11 3.9e-08 33.2 0.1 7 48 194 237 190 238 0.84

2 3 1.1e-08 3.3e-05 23.9 0.1 12 48 237 275 236 276 0.84

3 3 9.1e-13 2.8e-09 36.9 0.0 12 70 275 331 273 336 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.3e-11	3.9e-08	33.2	0.1	7	48	194	237	190	238	0.84
2	3	1.1e-08	3.3e-05	23.9	0.1	12	48	237	275	236	276	0.84
3	3	9.1e-13	2.8e-09	36.9	0.0	12	70	275	331	273	336	0.87

Sequence Information

Coding Sequence: ATGTCCGACGAAATGGCGGTTAGTGATAACCCGAGTGGAGCAGAAGCCGTTGTAATTAAAGCTGAAGCATTGGCAGCGAGTGCCGAGGACGCGGCGCCGGAGGCCCCCGAGTCCCCAAGTGCACCCGTGGACCCGGAGCCTGAAGAAACCCAGCCAATCAAACTAGAACCAGCAGAATGGAGTACATTGGAAGCCCCCGAGCCTGCCAAAGAACCCGATGATGACAAACGAGGTGTGAAACGCAGAGCGTCGGCCGCTTTCAGCAACACTGCAGATGAAGACTTTAAGGGCTTCGCTAAGATGGAGCTGAACGACTCCATTGAGGACTACAAGAGGGTTCTGGAAAATCTTGAAGCTGAAGTGGCAGCAGCGAGCAAAACAGTGGTGCCTCTCAGGACAGTGATGGGGACACCTACTGCTCCGGCCCGGGCAAGCAAGCGTGCCAGGCAAGACACAGATGGATCGAGACCTTCCTCAGCGCTGTCCTCCAGGTCTGAAGGTGACGGAGGGATTTCTTCCACTGAGGTCGGCTCATCGCGGTCCGGCCGCCGCGCCACGACAGAAATGTCCTCCCCGCTCCTTCGGGTCCCTCTAGAGAGGGGCTGGAAAAGGGAGCTAGTGTTCCGCGCCGCGCTCGACCAGCACTCGCGGCGCAATGCGGACATCTACTACTACACGCCGCAGGGCAAGAAGCTGCGGTCCACTAGAGAGAGGGGTTGGAAAAGGGAGCTAGTGTTCCGCGCCGCGCTCGATCAGCACTCGCAGCGCATCGCGGACATATACTACTACACGCCGCAGGGCAAGAAGCTGCGGTCCACTAGAGAGAGGGGTTGGAAAAGGGAGCTAGTGTTCCGCGCCGCGCTCGATCAGCACTCGCAGCGCATCGCGGACATATACTACTACACGCCGCAGGGCAAGAAGCTGCGGTCCACTAGAGAGGTAGCGGAACACCTCTCGGGAACAGGACTGACAGTAGATAACTTCTCGTTCTTCAAAGAACCACTGGGTGTAGATGACCCCGATAAAGAAATAATTCGTGACGCGAAGCTAATGCGGAAGGTGGAGTCTCCGGTGGCTCAGACGGCGCCCCCGGCGGAGGGCAAGCGCACGCCCAAGCCCAAGCCGCCGAAGGGCGCGAGTCCCGAGCCGCAGACCCCCAAGTCGCCGCCCGCCAAGATCAAGGTGAAGTCAATGCAGCCGCGCCTCAACCGCACGCCGGCCGCCACGCCGCCCGCCAGGAAGCCCGCCGCCGACAACAACAACACGCAAGCCTTGAAGAAGAACAGAACGGCGCCTCCGGCCCCCGTGGCCCCCGTGGCGCCCGCGGCCCCCGCGATCCTCGCGACCCCCTCGACCCTCGCGACCCCTGCGACCCCCGTGGCCCACGCGGCGCCGCCGCCGCTGCAGAGCCGGCCGCCCCCAGAGCCGGTTGATGCGAAGAATGAACCAGATGAGTTGACGTCTCCGCCGCGGCAGCTGGTGCAGCCGTGCTCGATGACGTGCGGCCGCGGCGTGCCCACGCTGGCGTGCGGCGCGTGCCTCTGCCTCTACCATCCCGCGTGCGCGGGGCTCGTCGCGCCGCGCGCGCCCGGGACATTCTTCTGCAAGAACTGTCGCAAATCGAGCTCTCCCTCGTCGTCTCCGCCGCCGCTCACGCACAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGAGCGGCGCCTGCGCGCTGGCCGCGCCGGCGCCGCGCCGCGCGCCCGCGCCGCAGCCCGCGCCGGCTGGCAAGCCCAGGCCGGCGCCGCCCGCGCCCGACAAGCGCGTCACGCTCAGGATGAAGGTAATCGAGCTCTCCCTCGTCGTCTCCGCCGCCGCTCCACCTTAG
Protein Sequence: MSDEMAVSDNPSGAEAVVIKAEALAASAEDAAPEAPESPSAPVDPEPEETQPIKLEPAEWSTLEAPEPAKEPDDDKRGVKRRASAAFSNTADEDFKGFAKMELNDSIEDYKRVLENLEAEVAAASKTVVPLRTVMGTPTAPARASKRARQDTDGSRPSSALSSRSEGDGGISSTEVGSSRSGRRATTEMSSPLLRVPLERGWKRELVFRAALDQHSRRNADIYYYTPQGKKLRSTRERGWKRELVFRAALDQHSQRIADIYYYTPQGKKLRSTRERGWKRELVFRAALDQHSQRIADIYYYTPQGKKLRSTREVAEHLSGTGLTVDNFSFFKEPLGVDDPDKEIIRDAKLMRKVESPVAQTAPPAEGKRTPKPKPPKGASPEPQTPKSPPAKIKVKSMQPRLNRTPAATPPARKPAADNNNTQALKKNRTAPPAPVAPVAPAAPAILATPSTLATPATPVAHAAPPPLQSRPPPEPVDAKNEPDELTSPPRQLVQPCSMTCGRGVPTLACGACLCLYHPACAGLVAPRAPGTFFCKNCRKSSSPSSSPPPLTHKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKSGACALAAPAPRRAPAPQPAPAGKPRPAPPAPDKRVTLRMKVIELSLVVSAAAPP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -