Basic Information

Gene Symbol
Zfpm1
Assembly
GCA_945869435.1
Location
CAMBUM010001246.1:28184-35033[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.071 6.9 8.8 0.1 6 23 25 42 24 42 0.98
2 8 0.0046 0.45 12.5 0.8 2 23 48 70 47 70 0.93
3 8 0.00015 0.015 17.2 0.1 2 23 86 106 85 106 0.96
4 8 2e-05 0.0019 20.0 0.6 1 20 112 131 112 134 0.92
5 8 0.00054 0.053 15.5 0.4 1 23 142 164 142 164 0.98
6 8 0.0011 0.11 14.5 7.2 1 23 170 192 170 192 0.98
7 8 1.4e-06 0.00013 23.6 1.4 1 23 198 222 198 222 0.98
8 8 0.022 2.1 10.4 2.1 1 23 228 250 228 251 0.95

Sequence Information

Coding Sequence
ATGTTGCAGCGTAATGTTAGGGACCGGCACCACCTGCACAAGAAGCGCGTGGTGCGCGACTTCGTGTGCGCGTGCGGCGCGGTGTTCCACTCGCGCGCCAAGCTGCGCTGGCACGCGGAGACACACGCGGCGCGGCCGCACGCGTGCCTGGCGTGCGGGGACAAGTTCGTACACGCGGCCAGTCTCACGCGGCACGTGCGGCGCGCGCACGACCCCGCCTACACCGACAcccggcgcccgcgccagccCAACCTGCCCTGTCCCGTCTGCAAGCAGGTGTACCTGCGGTCGAACCTGCGCGCGCACATGCTGACGCACAGTGGCAAGCGGCCGTTCGTGTGCGTGGTGTGCAACAAGGCCTTCACCACCAAGTGGAACCTCAAGCTGCACCGCTGGACGCACGCGTCGCGCTCCGCCAAGCCCTACAAGTGCGCGCTGTGCAAGGGCGCCTTCATCCGCCACTCCGAGTACGTCGCGCACATGAACGCGCACAAGGCCGTGCGCCCGTACACCTGCAACTACTGCGGCTGCCAGTTCATTCGCAAGTACAACTGCCAGCGCCACGTGCGCGAGCACGAGACCGCCAAGAAGTACGTGTGCAAGGTGGCCGAGTGCGGCAAGTCCTTCCACCGCTCCTACTACCTGTCCGAGCACATGAAGGTGCACAGCGGCGCGAGGCCCTTCGCGTGCGGCGTCTGCGGCAAGCTGTCCGGCAACAAGTCCAACCACAACAAGCACGTGCGCATCCACCACGCGCGCGAGCCCGTCGCCAGCGAGGCCTAG
Protein Sequence
MLQRNVRDRHHLHKKRVVRDFVCACGAVFHSRAKLRWHAETHAARPHACLACGDKFVHAASLTRHVRRAHDPAYTDTRRPRQPNLPCPVCKQVYLRSNLRAHMLTHSGKRPFVCVVCNKAFTTKWNLKLHRWTHASRSAKPYKCALCKGAFIRHSEYVAHMNAHKAVRPYTCNYCGCQFIRKYNCQRHVREHETAKKYVCKVAECGKSFHRSYYLSEHMKVHSGARPFACGVCGKLSGNKSNHNKHVRIHHAREPVASEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00148826;
90% Identity
iTF_00656520; iTF_00660603;
80% Identity
-