Basic Information

Insect: Epinotia demarniana
Gene Symbol: ZNF516
Assembly: GCA_945869435.1
Location: CAMBUM010000789.1:672189-681635[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 2.3e-07 2.3e-05 26.1 4.2 1 23 152 174 152 174 0.98

2 16 1.4e-05 0.0014 20.5 1.3 1 23 180 202 180 202 0.97

3 16 9.1e-08 8.9e-06 27.3 1.8 1 23 208 230 208 230 0.99

4 16 3.3e-07 3.2e-05 25.6 0.8 1 23 236 258 236 258 0.98

5 16 0.0013 0.13 14.2 4.6 1 23 283 305 283 305 0.98

6 16 0.00017 0.016 17.1 0.5 1 23 311 333 311 333 0.97

7 16 6.4e-05 0.0062 18.4 2.8 1 23 339 361 339 361 0.99

8 16 4.1e-07 4e-05 25.3 0.5 1 23 367 389 367 389 0.98

9 16 1.2e-06 0.00011 23.8 0.6 1 23 395 418 395 418 0.97

10 16 0.00015 0.015 17.2 1.1 1 23 430 453 430 453 0.95

11 16 4e-06 0.00039 22.2 5.0 1 23 460 482 460 482 0.97

12 16 0.00011 0.01 17.7 1.2 1 23 488 510 488 510 0.98

13 16 0.00091 0.089 14.7 1.7 1 23 516 538 516 538 0.97

14 16 7.5e-06 0.00073 21.3 4.6 1 23 544 566 544 566 0.98

15 16 0.00017 0.016 17.1 0.4 1 23 572 594 572 594 0.96

16 16 9.4e-07 9.1e-05 24.2 3.2 1 23 600 623 600 623 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	2.3e-07	2.3e-05	26.1	4.2	1	23	152	174	152	174	0.98
2	16	1.4e-05	0.0014	20.5	1.3	1	23	180	202	180	202	0.97
3	16	9.1e-08	8.9e-06	27.3	1.8	1	23	208	230	208	230	0.99
4	16	3.3e-07	3.2e-05	25.6	0.8	1	23	236	258	236	258	0.98
5	16	0.0013	0.13	14.2	4.6	1	23	283	305	283	305	0.98
6	16	0.00017	0.016	17.1	0.5	1	23	311	333	311	333	0.97
7	16	6.4e-05	0.0062	18.4	2.8	1	23	339	361	339	361	0.99
8	16	4.1e-07	4e-05	25.3	0.5	1	23	367	389	367	389	0.98
9	16	1.2e-06	0.00011	23.8	0.6	1	23	395	418	395	418	0.97
10	16	0.00015	0.015	17.2	1.1	1	23	430	453	430	453	0.95
11	16	4e-06	0.00039	22.2	5.0	1	23	460	482	460	482	0.97
12	16	0.00011	0.01	17.7	1.2	1	23	488	510	488	510	0.98
13	16	0.00091	0.089	14.7	1.7	1	23	516	538	516	538	0.97
14	16	7.5e-06	0.00073	21.3	4.6	1	23	544	566	544	566	0.98
15	16	0.00017	0.016	17.1	0.4	1	23	572	594	572	594	0.96
16	16	9.4e-07	9.1e-05	24.2	3.2	1	23	600	623	600	623	0.97

Sequence Information

Coding Sequence: ATGGAGTCTTTGCTCTCGTGTCATTGCTGCCTGCTTCGCCCTCCGGAGAAGGGACTTAGGACATTGTACAACCATCTCGGCAAAACAGAGATATATTCAGATATGCTGCGAGATTGTTTCGATATACAGATTAGTCCAAATGATGAGTGCGGTATCTGCGAGGTGTGCGTGCGCCGGCTGCGGGACGCGAGCGACTTCAAGCTGCAAGTGCAGCGCAGCCAGGCGGAGCTGCAGGCGCGGCTGCAGGGAGCACTGCATACACGTAATACTCCTCCCAAGTTGAATATCAAGCTAGAGAAAGCTTGTGGAACCAGGGCTGTTATAAGTGATATCAAGTTGGAGAAATCAGACGTCGACATGGGTGATGGGGAGGTTGTATCgcTGGCCCTCTACGGCGCTCCGCCCACGCCCTCGCAGTCTgcccccgcgccgcccgcgccccgcgGCACCGTCCACACCTGCGATATCTGCAATAAATCGTTCGACCACCAATCCGCGCTCAGAAACCACATGCGCATGCACACTGGAGAGAAACCCTATGCGTGCAACGTATGCAATAAGAAATTCGCACGCAGAGGCAACTTGAACGAACATTTCAAATATCACATGGGGATTTTACGATACTCCTGCAACATATGCAATAAGAGATTTATACAGAAGTCTTATTTGAAAGTGCATATGCTGACGCACACTGGAGAGAAGCCCTACAACTGTGAAGTATGTAATAAAAAATTCGCACAAAAAGGCAACTTGACCGTGCATTTGAAAACTCATGTGAAATCTGAAGGTAATCGTGAAGAAGAAAAGGAATGCAAAGAGTCGCAAGATTTGAAAGCAGGCAAACCATACGAATGTGAAGTGTGCAAGAAACGTTTCGCACAGAGATGCAACTTGAACTTCCATATGAAGTATCACATAGGGGATGATCGGTTTGCCTGTGATATATGCGAGAGGAAATTCACAAAACAGATCCTCTTGGACAAACATATACTTCGTCACACGAAGGGACCGCCGTACAAGTGTGACGAGTGCGATAGACAGTATAAATCGAAAACTGCTCTTTGCCTCCATTTAAAAATTCACGCAGGGGACTATAGATTTATTTGCGATGTGTGCAGTAAACGATTCATACAGAAAAGCGGTCTCATAAAACATATGCGTATACACACTGGAGAAAAGCCGTATGCCTGTGACATATGCCAAAAAGCATTTACAGTAAAATCTAATTTAACGTATCATTTGAGAGTCAAACACGGGCAAGGTGATCAGGGGGATCCAAACGCAGAGTTTCCATGCGAAACGTGCAATAAAAAATTCAAAGCTAAGTCTTCTTTGGATAGGCATGTCATGCAAAACCACACAGGAGACAGAAAAAAGTTTTGCTGTGAGATCTGCGGTAAACAATTTACACAAAAGCATACGTTGAATAAACATATGGATGTACATAAAGGAATAAAACCATTCATGTGCGAAATATGTAGTAAACGATTTAGGCTAAAACCTACCTTGAAAGCCCATAAACTGACACATTCGGATGAACGACCATACGCATGTGAAATATGCCAGAAGCGGTTCCGACTGACCAAATGTTTACAAGAACATATGGTGGTACATGAGAAAATCAAACGACACACCTGCGATGTATGCAGTAAGCAATTTAGACACAAATCCGCTTTAACTGTTCATATCCGACGCCACACAGGACAGAAACCGCACGCGTGTGATGTCTGTAATAAGGAGTTTATAGTGCTGGCCGAGTTGAAAACGCATTATCGTATTCACACCGGCGAGCAGCCTTTTATCTGTGAGATTTGTCATAAAAAGTTTTCGAGGCCGGATACTTTTAGGAGACATCTTAGACGCGTCCACAATAGAAAGCCCTCTAAAGGTGCGCTGTCGCAGTATGAGCGTCCGGCGGAAGTGGAGCCTAATGCTGGGTTTAGACGGTACGAGTCGTTGGCGCCAGTCGCGCTGGCTTACCACCGCTGGCAGGATGGGACTGTATAG
Protein Sequence: MESLLSCHCCLLRPPEKGLRTLYNHLGKTEIYSDMLRDCFDIQISPNDECGICEVCVRRLRDASDFKLQVQRSQAELQARLQGALHTRNTPPKLNIKLEKACGTRAVISDIKLEKSDVDMGDGEVVSLALYGAPPTPSQSAPAPPAPRGTVHTCDICNKSFDHQSALRNHMRMHTGEKPYACNVCNKKFARRGNLNEHFKYHMGILRYSCNICNKRFIQKSYLKVHMLTHTGEKPYNCEVCNKKFAQKGNLTVHLKTHVKSEGNREEEKECKESQDLKAGKPYECEVCKKRFAQRCNLNFHMKYHIGDDRFACDICERKFTKQILLDKHILRHTKGPPYKCDECDRQYKSKTALCLHLKIHAGDYRFICDVCSKRFIQKSGLIKHMRIHTGEKPYACDICQKAFTVKSNLTYHLRVKHGQGDQGDPNAEFPCETCNKKFKAKSSLDRHVMQNHTGDRKKFCCEICGKQFTQKHTLNKHMDVHKGIKPFMCEICSKRFRLKPTLKAHKLTHSDERPYACEICQKRFRLTKCLQEHMVVHEKIKRHTCDVCSKQFRHKSALTVHIRRHTGQKPHACDVCNKEFIVLAELKTHYRIHTGEQPFICEICHKKFSRPDTFRRHLRRVHNRKPSKGALSQYERPAEVEPNAGFRRYESLAPVALAYHRWQDGTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00657465;
90% Identity: iTF_00657465;
80% Identity: -