Basic Information

Gene Symbol
-
Assembly
GCA_963854355.1
Location
OY977939.1:5704377-5725030[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.051 6.5 9.4 0.6 5 23 295 315 293 315 0.90
2 14 0.045 5.8 9.5 0.5 5 23 366 386 364 386 0.90
3 14 0.045 5.8 9.5 0.5 5 23 437 457 435 457 0.90
4 14 0.0018 0.23 14.0 1.2 2 23 552 574 551 574 0.94
5 14 0.0018 0.23 14.0 0.1 1 23 580 602 580 602 0.97
6 14 0.044 5.7 9.6 0.2 1 23 610 633 610 633 0.88
7 14 1.1e-05 0.0014 21.0 2.3 1 23 638 660 638 660 0.98
8 14 2.1e-05 0.0027 20.0 0.8 1 23 666 688 666 688 0.96
9 14 0.00052 0.066 15.7 4.2 1 23 694 716 694 716 0.97
10 14 2.1e-07 2.7e-05 26.3 1.0 1 23 722 744 722 744 0.98
11 14 0.0024 0.31 13.5 4.4 1 23 750 772 750 772 0.98
12 14 0.0079 1 11.9 3.4 1 22 780 801 780 801 0.95
13 14 0.0019 0.24 13.9 0.2 1 23 809 831 809 831 0.97
14 14 1.9e-05 0.0025 20.2 0.8 1 21 837 857 837 858 0.95

Sequence Information

Coding Sequence
ATGGAAGTCTTTCTGTATAATTCTACTGTTTGTAGATTATGCGGAGAAGAAAATGACAACGGAACATTGTTATATTCAGCTGAGGAAAATAGTCAGAACTTAAGCGAAATTATTAATTCATATTTACCAATCAAGGTATCGGATGATGGACAATTACCGCGAACCATTTGTCCTGGGTGCACTATACAGATAGAAGCGACAGTGGAATTTATAACCTTAATTATAAATGGACagaaaataatTAGAGAGCTGTATCAGAGAGAGAAGGAATATAAGAAGACATTGTTGACCAATGCCACAGCTAGTGAGCCGCAGATCATCACTGAGAAGATTCTATATGAGATTAACACTAGCGATGGGGTATACCAAGTGGAGCACCCAATCGCCTTGCAAGTCGCCGGCTTGGAGAAGCCCAAACGCAAGCGCGGCAGGCCTCCCAAGAAGCCCAAGAGTCCCGAAGAACTGGCACAGGAGGCCGCTGCGAGACAGCAGGTCGTGGAGGCCAAGACCACCCAGAAGGAAGGAGAGGATGTGCCTGGGAAACGGAGGAGGAAAACACCTACGAGGTTTAAGGAAGCGGTTCAGGGGAAAGAGCTAGAGCGGATATTCAAAGAAGAAGGCGTGACAGACGGCGACGAGAGTGACAACGAGGCGAAGCCGGACTCCGGCGACAAGCCGCCCGTGTCTAAGGAGCCCGAGGTCATCGGGCACATGGAGGCCTCGGGGGAGCTCGTTGTTGTGGTCAAGGGCAAAGGCCGGGGGAGGCCGAAAGGTCGCATGCGACCGACCCGCGAGCAGTGCGCTATCTGCGGCATGGAGTTCTCGTGCGTCGGGCGCTACATGTCCCACGTGGCGGCGCACGGGCCCGTGCAGTATCGCTGCGGCTGCGGACAGACCTTCCCCACGCGGCTCACCTTCACCGCGCACCAGCGCAGCGCCAGGCACGAGGGCCAGACCGTGCTGCCCGCCGACCAGGTGAGAGCAGACCTGCGGCTGCGGACAGACCTTCCCCACGCGGCTCACCTTCACCGCGCACCAGCGCAGCGCCAGGCACGAGGGCCAGACCGTGCTGCCCGCCGACCAGAGCAGACCTGCGGCTGCGGACAGACCTTCCCCACGCGGCTCACCTTCACCGCGCACCAGCGCAGCGCCAGGCACGAGGGCCAGACCGTGCTGCCCGCCGACCAGGTGAGAGCAGACCTGCGGCTGCGGACAGACCTTCCCCACGCGGCTCACCTTCACCGCGCACCAGCGCAGCGCCAGGCACGAGGGCCAGACCGTGCTGCCCGCCGACCAGAGCAGACCTGCGGCTGCGGACAGACCTTCCCCACGCGGCTCACCTTCACCGCGCACCAGCGCAGCGCCAGGCACGAGGGCCAGACCGTGCTGCCCGCCGACCAGaaaccatTAAATCCCCAAACGCCTCCAATTAAAACGGAAACTCCACCAGAGCAGGAGCAATCCGAAGAACTACCATCAGTAGAGAAGCTAGTCAGCAACGTTCAGGACGCCACACTGCCGGCCGCCGTGCCGGATGCCGAGCAAGATGCCGGGCAGCCGGAGGAGAAACCGGAAATCCCACCGGAAACGACAGTGGAGACTGAAACGGAACCGGAAACGGTTGTACTTGGCCCCTCCGGGAAGCCGAAGATGAAATGTTCGCAGTGCGACAAAATGTTCAGCAATAAGCAGAGCCGCTCGCTTCACATTAAGGCAGTTCACGAGGGCTCGCGGCCATACTCGTGCGCAGAGTGCGGCGCGTCGTTCGCTTACCCGCGCTCGCTCGCACTACACGCGCACTCGCACCGGCGCGCACACCCGCGCGGGTTCGCTTGCGACCTCTGCGGGAAGGTCCTAAACCACCCGTCGTCCGTGGTGTACCACAAGGAGGCCGAGCACGCGGGCCAGCGCTACGTGTGCGGGAAGTGCGGGAAGCTGTTCAAACACAAGCAGCTGTTGCAGCGACACCAGCTGGTACACTCGCAGGCGCGCCCTTACAGCTGCAAGATCTGCAGCACATCGTTCAAGACGAAAGCGAACTTGCTGAACCACGCATTACTCCATTCCGGCGTCAAGCGATTCGCATGTGAACTGTGCAAACACCGCTTCGCGCACAAAACAAGCCTTACCCTGCACATGCGGTGGCACTCCgGTCTAAAACCCTACACCTGCAAAACGTGCGGCAAAAGTTTCAGTCAGAAAGGCAACCTGTCCGAACACGAGAGAATCCACACCGGCGAGAAGCCCTACCAGTGCACCCAGTGTCCCCGCCGCTTCACCACGAGCAGTCAACACCGGCTACACGCGAGGAGACACCAGGCGGACACAGAGCGGCCACACATCTGCAATCACTGCGGGAAGCGTTTCGTGTGCCGCTCATCGTGGCTGGCGCACATGCGGCGCGAGACACGTGGCGCGGCGCGGCACCGCTGCGGCGCGTGCGGCCGTGCCTTCGCCGAGCGCTGGGCGCTGCTCAAGCACGCGCGCAGGCACACCGGCGAGCGGCCCTTCCGCTGTCCGCTCTGTCCGCGCGCCTTCGCGGACTGCTCCAACCTCAACAAGCACAAAAAGGTACTGTGA
Protein Sequence
MEVFLYNSTVCRLCGEENDNGTLLYSAEENSQNLSEIINSYLPIKVSDDGQLPRTICPGCTIQIEATVEFITLIINGQKIIRELYQREKEYKKTLLTNATASEPQIITEKILYEINTSDGVYQVEHPIALQVAGLEKPKRKRGRPPKKPKSPEELAQEAAARQQVVEAKTTQKEGEDVPGKRRRKTPTRFKEAVQGKELERIFKEEGVTDGDESDNEAKPDSGDKPPVSKEPEVIGHMEASGELVVVVKGKGRGRPKGRMRPTREQCAICGMEFSCVGRYMSHVAAHGPVQYRCGCGQTFPTRLTFTAHQRSARHEGQTVLPADQVRADLRLRTDLPHAAHLHRAPAQRQARGPDRAARRPEQTCGCGQTFPTRLTFTAHQRSARHEGQTVLPADQVRADLRLRTDLPHAAHLHRAPAQRQARGPDRAARRPEQTCGCGQTFPTRLTFTAHQRSARHEGQTVLPADQKPLNPQTPPIKTETPPEQEQSEELPSVEKLVSNVQDATLPAAVPDAEQDAGQPEEKPEIPPETTVETETEPETVVLGPSGKPKMKCSQCDKMFSNKQSRSLHIKAVHEGSRPYSCAECGASFAYPRSLALHAHSHRRAHPRGFACDLCGKVLNHPSSVVYHKEAEHAGQRYVCGKCGKLFKHKQLLQRHQLVHSQARPYSCKICSTSFKTKANLLNHALLHSGVKRFACELCKHRFAHKTSLTLHMRWHSGLKPYTCKTCGKSFSQKGNLSEHERIHTGEKPYQCTQCPRRFTTSSQHRLHARRHQADTERPHICNHCGKRFVCRSSWLAHMRRETRGAARHRCGACGRAFAERWALLKHARRHTGERPFRCPLCPRAFADCSNLNKHKKVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00659731; iTF_00658781;
90% Identity
-
80% Identity
-