Basic Information

Gene Symbol
-
Assembly
GCA_947049265.1
Location
CAMRIQ010000271.1:1370382-1394095[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.48 39 6.1 0.2 1 23 346 368 346 368 0.97
2 11 0.00086 0.069 14.7 6.6 1 23 375 397 375 398 0.95
3 11 0.096 7.8 8.3 1.8 1 23 402 424 402 424 0.97
4 11 1.1 87 5.0 3.5 1 23 429 452 429 452 0.97
5 11 0.012 0.95 11.2 0.4 1 23 456 479 456 479 0.94
6 11 0.0037 0.3 12.7 0.5 3 21 493 511 492 516 0.93
7 11 1.5 1.3e+02 4.5 0.4 2 23 571 593 570 593 0.94
8 11 0.015 1.2 10.9 1.0 2 20 609 627 608 630 0.89
9 11 3.5e-05 0.0028 19.1 1.4 1 23 636 658 636 658 0.99
10 11 1.9e-05 0.0015 19.9 5.1 1 23 665 687 665 687 0.98
11 11 7.2e-05 0.0059 18.1 4.1 1 23 693 716 693 716 0.95

Sequence Information

Coding Sequence
ATGCGGTGTTGCGTTCCCGGCTGCAAAAATGACTCGAGACATATCTCAAAGTCCCAAGGAATCACTTTTCATGTCTTTCCGACCGAGTCGTCCCTCCGATCCTCCTGGCTCCAGGCCCTTGGCAAAGAATCATGGGAGCCGAAGGAGCGCAGCGCCGTCTGCTCCGATCACTTTCTTTGCGAAGACTTGTACGAGACAAAGAGTGGGTTACGGAAAGTGAGGGCCGGTGCTGTGCCGATCATTCTGCAGGATCCGAGTGGATGTCGGTTGGAAGCCGGTTTGAAGGCGTGTCGTATATGCCTGGCGGTGGACGGCAGCCTTCTCGCGATCACGCACCGGCTCGAGGAGGCCTATCACCATCTCACTGGGATTGCGTGCAAAGAGAAGCTGCCCCAACAACTATGTGTGGAATGCGCTCAGCGGCTGCTGAACAGCAGCAAACTCAGGAGCAAGAGTTTGAGGGCGCACTCCATCATGATGGAGATCGTCAGGAGACAGGATAGCCTAACACTCCAAACCCTATCCACGATAAGCAGAGAGAATAATAGACTAACTTCAGCCCTAAAACCTAAACACCACGAACCTAACTACTACAACGTAACCTTAGACCACGACACGATAGACCAAGAGCCACCAATCTGCGAAGTCAATATCGCAGATGAAATCGTGATCAAAAATGAAAACAGTGACGTATTCAATGAGGTTAATGATGTCAATGAGAACTGTGCGCATGAAATTGACAATGATGCCGATTTTGTGGTAGATAGGGATTATTCTACTGATGACAGTTTGCCACTGGTAGCTAGGAGGAGAAAAAAGGAGAGTAAGAAGAAGATAGAGAAGAAAGAGGTTATTAAAaagGTGCGAAAGAGACAGGTAAAGGATCCAACGCAGCCGAAGATCGACCGGCGACGGAAACCGTTCTTGAACGACGAACTGAATGAAACCCTCTTCACCATCACTGACTTGACTCAAGCGGAACAGCTGCAAGAAATACAGAAGCGACAGGAGACTTCCAACTACAAAAATTCGGTGTTCAAATGCGAAGCGTGCTTCAAAGGGTTTCTCGACGAGGACGCGTACAACAGTCATATTGTTAGACACACCGATCAATGCGGCGAATATGAATGCGGCATATGCAAGACCCACTTCAAGCACCCGCACGCGTTACGCAAGCACATAACCGCTCACCACACGCAGCGGTTCAGCTGCAACCAATGCCCATATGTCACCACGCACCGACAGACGGCCCGACTTCACGAGCGATGGCACAAGGGGACCAAATACCACTGCCCGCACTGCCAGGACGAGTTTGTCAAGTTCACGACGTACATGGGTCATATACGCATCAAGCACCCTTCGGACTTCGTCTGCCAGCTCTGCGGGTACTCCTTCGTGAGCGAGAAAGGGATAGAGCTACACAAGAAGCTGAAACACAGGCTGGAAGACCCTCAGATACCAGATGACGGTCCGTTCTGCGAGCTTTGCAACGTGCGGTTTGTGTCCAACGAGGCCCTGAGGAGACACATACACGTGTCGGCGAGACACGCGGGCAGCGACAAAGACAAAGAGCTGAACAAGTCCTCGAGGCCCCGAAAGCCGCGGGAGACGAACGCGTCGCGgcagcgggagcgggagcgggagcggtcGCGGAGCGCGTCGAGCGAGCGCCGGCACCCCGGACACATGAGGAAGGCCGAGGGACCGATACCATGCGAACAGTGCGGTATGCAGCTAGAAGACTCGCGTGCTTACCACGGCCACTTCCGTCGAATGCACCCGGACAAGAATCGAACCAACTACCCGTCTATGAAGTCGCCTTGTATGTGCGAAGTGTGCGGGCGCATGTTCCAGAGTTACGCCCTCCTAAAAGACCACACGTGGACCCACACTGGCGAACGTCCTTTCAAGTGTGACTCATGCGGAAAGTCATTCCGCATGAAGCAGCGGCTCGTGGCGCACCGGCGCGTGCACAGCGCGCAGCGCGCCACCTACGTGTGCAGCGTCTGCGGGAAACACTTCAGCACGCACAGCAACCGGCAGCGGCACATGTTTATCCACACCGGATTAAAACCATTCAAGTGCGAGATGTGCGGGAAATGTTTCAAGCACGCGAGCGAAAAGCGCGCGCACATCACGTACGTGCACCTCAAGAAACCGTGGCCCAAGCGCGCGCGCGGCAAGCGGCGCGACTCCAGACAGGGCATGCCGCACCCGCAAATGTCAGGGGCCACGAGTGCGAGCGAGATGGACATAGTTCAGCCGCTCTGGCCGTCATGCGATCCGAAGCTAGCCGACATCAACGCGATGATGGACGATAAGCCTATGTATTATaacctcaaaatatag
Protein Sequence
MRCCVPGCKNDSRHISKSQGITFHVFPTESSLRSSWLQALGKESWEPKERSAVCSDHFLCEDLYETKSGLRKVRAGAVPIILQDPSGCRLEAGLKACRICLAVDGSLLAITHRLEEAYHHLTGIACKEKLPQQLCVECAQRLLNSSKLRSKSLRAHSIMMEIVRRQDSLTLQTLSTISRENNRLTSALKPKHHEPNYYNVTLDHDTIDQEPPICEVNIADEIVIKNENSDVFNEVNDVNENCAHEIDNDADFVVDRDYSTDDSLPLVARRRKKESKKKIEKKEVIKKVRKRQVKDPTQPKIDRRRKPFLNDELNETLFTITDLTQAEQLQEIQKRQETSNYKNSVFKCEACFKGFLDEDAYNSHIVRHTDQCGEYECGICKTHFKHPHALRKHITAHHTQRFSCNQCPYVTTHRQTARLHERWHKGTKYHCPHCQDEFVKFTTYMGHIRIKHPSDFVCQLCGYSFVSEKGIELHKKLKHRLEDPQIPDDGPFCELCNVRFVSNEALRRHIHVSARHAGSDKDKELNKSSRPRKPRETNASRQRERERERSRSASSERRHPGHMRKAEGPIPCEQCGMQLEDSRAYHGHFRRMHPDKNRTNYPSMKSPCMCEVCGRMFQSYALLKDHTWTHTGERPFKCDSCGKSFRMKQRLVAHRRVHSAQRATYVCSVCGKHFSTHSNRQRHMFIHTGLKPFKCEMCGKCFKHASEKRAHITYVHLKKPWPKRARGKRRDSRQGMPHPQMSGATSASEMDIVQPLWPSCDPKLADINAMMDDKPMYYNLKI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00411872;
90% Identity
iTF_00657685;
80% Identity
iTF_00656206;