Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.13 1.4e+03 0.7 0.1 26 49 133 156 130 162 0.82

2 5 0.00028 3 9.2 0.2 17 52 162 198 157 200 0.83

3 5 0.00016 1.7 10.0 0.1 23 47 225 249 218 254 0.85

4 5 3.1e-05 0.33 12.3 0.1 21 51 251 281 247 283 0.87

5 5 0.017 1.8e+02 3.6 0.0 22 43 280 301 277 305 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.13	1.4e+03	0.7	0.1	26	49	133	156	130	162	0.82
2	5	0.00028	3	9.2	0.2	17	52	162	198	157	200	0.83
3	5	0.00016	1.7	10.0	0.1	23	47	225	249	218	254	0.85
4	5	3.1e-05	0.33	12.3	0.1	21	51	251	281	247	283	0.87
5	5	0.017	1.8e+02	3.6	0.0	22	43	280	301	277	305	0.91

Coding Sequence: ATGTCGCTGGCGGCGCTCGCGCAGGAGCCCGAGCGTGTGGTCACAGACCGAATGTGCATTAAGATAAAAGCCAAGTCAAATGAAGAAGTGGAGGTATTGAGACAGGAGGAGGAGCATGTGACACGGGAAACCGCAGCCATCAAGCAGGAGCTGTCGTGGGAGCACAGCAGTGACCTCTATGCCGGTCACGAGGTTAAACAGGAACTTGTGTTGGGACCGGAATGCTTGCAGCGGCCGGGGTCGGTCATAGCTCAATTCGTTGATGGAGCGGGCCGGGCGCACGCCACAGCCACAGCCACACCCCGCGcggccgccggcgccggcgccgacaCCGCGAGCGCTGAACAGGAAACTGACGCGAAATACAAACAAACTATTGTGGAGATTAATACTTACATGTGCGACATTTGTGGTAAATTATTCAtgcacaaaaataaattaattcgcCATATTCGCCAGATGCACCTGCAGGCAAAACAGGGTGATCGTAGTCCCACTGGCCAAAAGGCATTTTTCTGCAAGATATGTAACAAGAAGTTCAGGCAGGCCGGCCACTTGAATCGACACGAGCAAACTCACACCGGAGCAAAGCCACATACCTGCGAGAAGTGTGGGAAGGAGTTCACGCGACTGGACACGCTGAAGCTGCATAGAATCATTCACACGGGAAGCAAACCCTACTCCTGCGAGATGTGCTACAAACAGTTCACGCAGTTGAGTAATTTGACTAGACACACGAGAATACACACTGGAGAGAAACCTTATCCTTGCTCTATATGTTTTAAGCGGTTTACTCAAtcatatgatttaaaaaaacatattcgtATCCACACTGGTGACAAACCATATTCTTGTGAAATATGTTCGAAGCTGTTCACCTGTTCCGGGGATTTAAGGACACATAATCGTACTGCGGGACATAAACGTGCAGTACGGACTTTGAACCGCAGAAAAAAGTAA
Protein Sequence: MSLAALAQEPERVVTDRMCIKIKAKSNEEVEVLRQEEEHVTRETAAIKQELSWEHSSDLYAGHEVKQELVLGPECLQRPGSVIAQFVDGAGRAHATATATPRAAAGAGADTASAEQETDAKYKQTIVEINTYMCDICGKLFMHKNKLIRHIRQMHLQAKQGDRSPTGQKAFFCKICNKKFRQAGHLNRHEQTHTGAKPHTCEKCGKEFTRLDTLKLHRIIHTGSKPYSCEMCYKQFTQLSNLTRHTRIHTGEKPYPCSICFKRFTQSYDLKKHIRIHTGDKPYSCEICSKLFTCSGDLRTHNRTAGHKRAVRTLNRRKK

Sequence clustering based on sequence similarity using MMseqs2