Basic Information

Insect: Ephialtes manifestator
Gene Symbol: IKZF4
Assembly: GCA_963970395.1
Location: OZ019968.1:33100241-33112270[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 2.6 4.9e+02 2.9 0.1 1 23 88 113 88 113 0.87

2 19 1.7 3.1e+02 3.5 8.1 1 19 120 138 120 143 0.93

3 19 0.00069 0.13 14.2 0.3 2 23 159 180 158 181 0.95

4 19 8.7 1.6e+03 1.3 5.4 1 23 187 209 187 209 0.97

5 19 0.0064 1.2 11.1 0.7 2 23 215 236 214 236 0.97

6 19 0.014 2.6 10.1 3.0 2 21 520 539 519 540 0.95

7 19 2.6 4.9e+02 2.9 1.0 1 23 608 630 608 630 0.82

8 19 5.4 1e+03 1.9 1.8 2 23 811 832 810 832 0.96

9 19 0.021 3.9 9.5 0.2 1 23 848 870 848 870 0.94

10 19 0.011 2.1 10.4 0.2 1 23 878 900 878 900 0.98

11 19 0.3 57 5.9 2.4 2 23 990 1011 989 1011 0.95

12 19 0.83 1.6e+02 4.5 0.8 3 23 1023 1043 1022 1043 0.95

13 19 0.0036 0.68 11.9 0.2 1 23 1120 1142 1120 1142 0.98

14 19 0.04 7.7 8.6 0.3 1 23 1225 1247 1225 1247 0.97

15 19 0.0001 0.019 16.8 0.4 1 23 1253 1275 1253 1275 0.97

16 19 0.006 1.1 11.2 2.6 1 23 1323 1345 1323 1345 0.97

17 19 0.00041 0.077 14.9 1.5 1 23 1351 1373 1351 1373 0.99

18 19 0.034 6.5 8.8 0.3 2 23 1468 1489 1467 1489 0.97

19 19 5.2 9.8e+02 2.0 0.3 2 23 1497 1518 1497 1518 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	2.6	4.9e+02	2.9	0.1	1	23	88	113	88	113	0.87
2	19	1.7	3.1e+02	3.5	8.1	1	19	120	138	120	143	0.93
3	19	0.00069	0.13	14.2	0.3	2	23	159	180	158	181	0.95
4	19	8.7	1.6e+03	1.3	5.4	1	23	187	209	187	209	0.97
5	19	0.0064	1.2	11.1	0.7	2	23	215	236	214	236	0.97
6	19	0.014	2.6	10.1	3.0	2	21	520	539	519	540	0.95
7	19	2.6	4.9e+02	2.9	1.0	1	23	608	630	608	630	0.82
8	19	5.4	1e+03	1.9	1.8	2	23	811	832	810	832	0.96
9	19	0.021	3.9	9.5	0.2	1	23	848	870	848	870	0.94
10	19	0.011	2.1	10.4	0.2	1	23	878	900	878	900	0.98
11	19	0.3	57	5.9	2.4	2	23	990	1011	989	1011	0.95
12	19	0.83	1.6e+02	4.5	0.8	3	23	1023	1043	1022	1043	0.95
13	19	0.0036	0.68	11.9	0.2	1	23	1120	1142	1120	1142	0.98
14	19	0.04	7.7	8.6	0.3	1	23	1225	1247	1225	1247	0.97
15	19	0.0001	0.019	16.8	0.4	1	23	1253	1275	1253	1275	0.97
16	19	0.006	1.1	11.2	2.6	1	23	1323	1345	1323	1345	0.97
17	19	0.00041	0.077	14.9	1.5	1	23	1351	1373	1351	1373	0.99
18	19	0.034	6.5	8.8	0.3	2	23	1468	1489	1467	1489	0.97
19	19	5.2	9.8e+02	2.0	0.3	2	23	1497	1518	1497	1518	0.86

Sequence Information

Coding Sequence: ATGTCAGAACGTTCGCCACGCCTTCGAGGATTGAGGCCTCGAAATAAGCATCGTTCTCTGCAGAGGCAAACAGTCCAGAGCGAAGTTTCGGATGGAGAAGAAGCAGAAGAGAGTGCTAATAGGAGGACAAATAGCAAAGATCGGAATGTTGACAATTCAGTGAATTTGAGAAACGACAGTGATGACAATGAGCTTCATATTGAAATAAAGGATGAACAGGATGAGGCTGCTTCTGATGAGAAATCagattctgacagaaattatgAGTGCAAGAATTGCAAGACTCCTGTTGGATTTCCAACCCTTGTGGAGTACCTCCAGCATCTCAGGGATGAACACAAAGAAAAGGGGCGAAGTTACGAGTGTCCGCACTGCGATTTCAAATGCCAGCATCCGAAAAAATTGAAGGCGCATTGTGACAGCGATCACAAAGACTTGCAAGACGTTCCGACTTCCGAAGAATCGGTTCCAAATAAATGCACGATGTGTCCTTACATCGCGGCAAACGCGAGCGAACTGGAAAATCACCAACGCGTTCATCATCTCAAAAGACGATTTTTCCGATGTACGAAGTGTTCGTACATGACTCATGTGCGAGCACGATACACCAAACATGTAAAATATCATTCAATGCCGATGATTAAGTGCCTCGACTGCGACTTTCGAACACCGTACAAGTGGAATTTGGACAGACATACGCGAAATCACGGCGGCGGCGGAACGTTTCAATGCAGAGCGTGTAATTTCACAGCAGATATTCGTCAGAGTTTGACTGTGCACGAAACGAATCATCACGAGCCGCCAGTTGGTCAAACTAACCGAAAGCTCAACACACCTTTCGAGCGGAAACCCCGAAACGGTCCAAAACGTTATAATCAGGTAGGAGCGAGCGATTTTCGAGATATGCCGAATTCAGAGAGTCCTGCATCTGTGAAAGCCAAGAGTCCAGTTACGTCACCAATTTCCGATGGAGCCGGAAGTTCTCTGGAGGATAGAAGAAACGCTATGTCCGGCGCTGAATGCATAGCACTGAAATGCGAGGAAAAAGGCTGCCAGTTTATCACAGCGTGGGACTCGGAGATGCAACGGCACTTGGCGGAATCTCATGCGCCTTCAACTTCGCCTGTTCGGTCAAGGAAACCTCTGCCGATGCTTATTCCATTGAGTCCTGAGAGTAGCGCGAAATCGATAAACTCGGCGACGAACGGATCTTCGACGACGCTGCTCAAGGTCCCGCGGGTTCGAGTCAGGCCGGAACTCGCGAAAATCGCGAGGGACACAGAAATGGCCAAACTCTATGGAAACAAAGAGCCTAGCAGCACGAAAAAGGACACAGGGATCGGAGACTCTTTTGAGAAAAGGAACGCCTCGTTCTTCGACAAGCTCAAGGAAAGATTGATGACTACGAGCGCGAGCATCGCGGGTGTGCCGCAAGTAGCCGTAAGTAGTGCGAACGATTTAAAGTGTTGGTGTACCTTCGAAGCGAGTAGCCCGGAGGAATTGGCCAGTCATAGTCAGACGCATCACACAGCACTGAGTGTATCCGTCGGGGTATCGCGCTGCCCTAAGTGTAGAAGGCGTTGTAAGAGTTCCACCGATCTTCAAATGCACACGAGACTTTGTCAAGCGACGGTGAATGATTTAATGACGAGCGATAATTGTCCGGAGAGTCCAGCAAATAGTACGAATTATACATCCGCCTCCTACAGTGGTGATTTTGAGTTTCCGTTTCAAGTGGACTGGGACGGGAGTTTTGGAGGACTGAATTCTTCTGGATCGTCGGTCGAGGGAGTTTCGGGCCACCCACTCGGACGTCGGGTATTCAAGTGTCCTCATTGCCCATTCTGGGCTTCAACCGCCAGCAGATTTCACGTACACATTGTCGGTCATTTGAATCGAAAGCCGTTCGAGTGTTCGCTCTGCGCGTACAGATCGAACTGGCGATGGGACATTACAAAGCACATCAAGCTCAAGGCGGCTAGAGATCCGGCTCACATGGCCGCCAGGGTGCTTATGACTGACGAAACTGGCCGACGTAATTATTCCAAATACAACAAATATCTTGCTCAGGTCGAACAACAAGGTGCCGAGGAATCTGGCCTCGAGGAAGGACCCGCAGGAGAATCGCGAATCGACGAGCCACCAAAGAAAATTCTCATACTGGGCGATCCAAAGGAATATTCGGGAGGTCCCCCCGAACTCACACCAGCACCGAGCGTCGATCAAGCTGAAACAAATTCTATGAGCATCCTTACGGCTCTGAACTTAAGGCCGCCACCTCCTCTAAAATCTGCTGCCAGAAGTCAGGGACAATCTTTGTTGAAAAATAGTCCAACCGCTTCTACGGCAATTTCCATATTATCGACTTCAGGAACAACACCTGCGACAGCAAACGTTTCCGGGACTGACGAGACTAAACGCACTCTGTGGAAGTGTAAGCGATGCAACTTCCGTGATTCCAACAAAGAAACTGTTTTGACTCACGTTAAGACTCACTATGATTCGCTAGAACATGCGAGCCCAGACAGCGAAAAGAGCGAATTCACATGTCCTGATTGTCCGTATACGTCGAACGATCCAACTGCTATGGCGATACATCGCGTTCATCATCGTCCGAATCTCGAGGCCATCTTCAAATGTTACCTTTGTCCATATTACGTCAGCACAAAAGCAGAATTACTGGAACACGCGAGACTTCACGGTGAGGAGCTAGCAGTGGTTCACCAGAGAAGCATCGATTCTCTATCCCCGACAAAACAAAAGTCTTCTCAGCAAGCGTCATCGGACAATGAAACATCATCAAAATCCGAAGTCGCAGTCGAGGAAATCGTAAGTTCAGTTCCAACAACGAGCGAGAATTTGAGTCCGGAAGAAGTGGCGCCACCGTTATTACTAGACACTCGTGCCTTGCCCGACACGCCATTGGTATGGGTTTCCCGGTCCGATGGCACTCTCGCCAAAATGCTCAAGTGTCGTCACTGTCCCCACGTATCTTCTCGCCGCGCTGAAGTTCGTGATCACGAAACGATGCACGTTAATTCGCCAACTTCCGGACCTCTAGTAGCGTGTCGCGATTGCAGTTTCACTTGTTCGCGACGCGACGTTATGGAAGCTCACGCAGATATGCACATGGGTTCACTAGGCACCGTGCATTGTCTCGTAGACGAGGGCCGCACGGATGCGCAGCAGTTGGACGACCTCACGACCCTTCTCGGCCTCTCCAGAAAACCAACTCTCGGCCCTGAACCCGATCTTCGAGACTCTCGTCTCGTTCACTGCTGTTCAAAATGTCCAGCTCGATTTCTCTGTGAAAAAGAACTACGGATTCATCTGCGTTATCATTCCACAGAGTTAGCGTATTCGTGCCAATGGTGCTCATACGCAGCTCGTCAACCCGCGCATCTTTTGGCTCATCAAAAAGCACATTCCTCCGAATATCAGGACCGCACTCGATACTTATTGTCGATTTACGGTCACTCCCAGCGATACGCGCCGCCAAATACTGCCTGCGTGGAATCAAACGATCGACAACCTTCGGAAAATGTTCGAGGGGAAAGATCTACCAATAGATCTACGAACGTCGCTTGGATAGTCGTTGAAATCGTCGCAAATTCCGCTCAAAGCTGCTCCTCGAATCCAGAGAGCAGCGAGCAGAAAAATGGTAATCAAGTGTTTACTTGTGCTAAATGTCCTGCGCGTTACTTTAaactcgatgcgctcgagtatCACATGACGCTTCACGGATCCAACAATAGATTCAAGTGCGCGGAGTGCGATTATTCCTCGAAAACTGCGCAAAATTTGATGAAGCATCAGGTGGTTCATCGTCGTCACGTTGAAGCCAGCGAACCTCCAGCTACTCGCACCCTTCCACCGCCGGATCCACAATTCGGTGTTAGCATGAGAGGCAATCCGAATTTCGTGTATCCAGGCTGCTTGAGAAACGGAAGAATGAAGGAAAAACGTTATAAGTGCCATAAATGtccttctgctttcgaaaaacGGGAGCAGTATCGCGTGCATCTTACACTTCATGGAGCTAAACAGCGTTATCGTTGCGACAAATGCGACTATTCGGTTAAATATTATGCGAATTACGCTCAGCATATAAAGAAACATCAAGCTAATGCTCAGGCTCAAGCATCACGAAGACAATTTGAAGCCGAAGCTATTACCGTTGACAGCGACAGTGTTACGGAAGCCGAAAGTCCTGATCCCCGAAGCTCGAAGAATCGAAGAAAATCAACAATTTCATCGGGTACCGCAGCAACGTATGAAAATGGTAACATTGCTGGATCAACAGCAGTGTTGCAAGCTTCCAATCAAGACAAACAATCGGTTATGTTAATGCAGAAAAAAGGCGTTCCTGTAGCTCTTTCCGAGGCAAACAACAGACTCATCCGATGTCAGGATTGTCCGTTTTCTGGATCTGACAAAGAAGCGATGGATTCTCACCGCCGTCGTCACGGTATTGAGAGGCTTACGCCGTCCTGTCCTCATTGCAATTACGTTCCTCGCAAAGACGAAAATGTCGGGGAACACATAAGATTGCATTTCACTAGACTTTATAAACCTGAGTCTTATCTTATCGTGGAGCTTCTTTCGCTCACTGTGCGATCTCTATTTCCCGAAAAGAAGGATCAGAAATACAAGGAACCGGAGATTCTCTTCCGCGAATGCGCAGATGGAAACTATTTGCCGGTTACTGACTCGGTTCTTCAGTCACCTGCCGCGCCTTCCAACGCTAATGGGTATCAAGAAAAAGTTATTGTGGATCCTAACACAGGTGAGACGAAACATCGTTATTCCGCATAA
Protein Sequence: MSERSPRLRGLRPRNKHRSLQRQTVQSEVSDGEEAEESANRRTNSKDRNVDNSVNLRNDSDDNELHIEIKDEQDEAASDEKSDSDRNYECKNCKTPVGFPTLVEYLQHLRDEHKEKGRSYECPHCDFKCQHPKKLKAHCDSDHKDLQDVPTSEESVPNKCTMCPYIAANASELENHQRVHHLKRRFFRCTKCSYMTHVRARYTKHVKYHSMPMIKCLDCDFRTPYKWNLDRHTRNHGGGGTFQCRACNFTADIRQSLTVHETNHHEPPVGQTNRKLNTPFERKPRNGPKRYNQVGASDFRDMPNSESPASVKAKSPVTSPISDGAGSSLEDRRNAMSGAECIALKCEEKGCQFITAWDSEMQRHLAESHAPSTSPVRSRKPLPMLIPLSPESSAKSINSATNGSSTTLLKVPRVRVRPELAKIARDTEMAKLYGNKEPSSTKKDTGIGDSFEKRNASFFDKLKERLMTTSASIAGVPQVAVSSANDLKCWCTFEASSPEELASHSQTHHTALSVSVGVSRCPKCRRRCKSSTDLQMHTRLCQATVNDLMTSDNCPESPANSTNYTSASYSGDFEFPFQVDWDGSFGGLNSSGSSVEGVSGHPLGRRVFKCPHCPFWASTASRFHVHIVGHLNRKPFECSLCAYRSNWRWDITKHIKLKAARDPAHMAARVLMTDETGRRNYSKYNKYLAQVEQQGAEESGLEEGPAGESRIDEPPKKILILGDPKEYSGGPPELTPAPSVDQAETNSMSILTALNLRPPPPLKSAARSQGQSLLKNSPTASTAISILSTSGTTPATANVSGTDETKRTLWKCKRCNFRDSNKETVLTHVKTHYDSLEHASPDSEKSEFTCPDCPYTSNDPTAMAIHRVHHRPNLEAIFKCYLCPYYVSTKAELLEHARLHGEELAVVHQRSIDSLSPTKQKSSQQASSDNETSSKSEVAVEEIVSSVPTTSENLSPEEVAPPLLLDTRALPDTPLVWVSRSDGTLAKMLKCRHCPHVSSRRAEVRDHETMHVNSPTSGPLVACRDCSFTCSRRDVMEAHADMHMGSLGTVHCLVDEGRTDAQQLDDLTTLLGLSRKPTLGPEPDLRDSRLVHCCSKCPARFLCEKELRIHLRYHSTELAYSCQWCSYAARQPAHLLAHQKAHSSEYQDRTRYLLSIYGHSQRYAPPNTACVESNDRQPSENVRGERSTNRSTNVAWIVVEIVANSAQSCSSNPESSEQKNGNQVFTCAKCPARYFKLDALEYHMTLHGSNNRFKCAECDYSSKTAQNLMKHQVVHRRHVEASEPPATRTLPPPDPQFGVSMRGNPNFVYPGCLRNGRMKEKRYKCHKCPSAFEKREQYRVHLTLHGAKQRYRCDKCDYSVKYYANYAQHIKKHQANAQAQASRRQFEAEAITVDSDSVTEAESPDPRSSKNRRKSTISSGTAATYENGNIAGSTAVLQASNQDKQSVMLMQKKGVPVALSEANNRLIRCQDCPFSGSDKEAMDSHRRRHGIERLTPSCPHCNYVPRKDENVGEHIRLHFTRLYKPESYLIVELLSLTVRSLFPEKKDQKYKEPEILFRECADGNYLPVTDSVLQSPAAPSNANGYQEKVIVDPNTGETKHRYSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00343476; iTF_01497782; iTF_00398404; iTF_00905729; iTF_00721608; iTF_00059762; iTF_01364986; iTF_00059035; iTF_00058272; iTF_00397631; iTF_00841408; iTF_01207687; iTF_00414643;
90% Identity: iTF_01497782;
80% Identity: -