Basic Information

Insect: Clistopyga incitator
Gene Symbol: IKZF4
Assembly: GCA_947507545.1
Location: OX382175.1:3370358-3376899[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.77 82 4.3 0.1 1 23 88 113 88 113 0.92

2 18 1.4 1.4e+02 3.5 8.1 1 19 120 138 120 143 0.93

3 18 0.00086 0.092 13.6 0.2 2 23 159 180 159 181 0.95

4 18 7.1 7.5e+02 1.3 5.4 1 23 187 209 187 209 0.97

5 18 0.0053 0.56 11.1 0.7 2 23 215 236 214 236 0.97

6 18 0.0015 0.16 12.8 2.9 2 21 520 539 519 540 0.96

7 18 2.1 2.2e+02 2.9 1.0 1 23 608 630 608 630 0.82

8 18 0.017 1.8 9.5 0.2 1 23 846 868 846 868 0.94

9 18 0.009 0.96 10.4 0.2 1 23 876 898 876 898 0.98

10 18 0.24 26 5.9 2.4 2 23 988 1009 987 1009 0.95

11 18 5.7 6.1e+02 1.6 0.9 3 23 1021 1041 1020 1041 0.90

12 18 0.0029 0.31 11.9 0.2 1 23 1118 1140 1118 1140 0.98

13 18 0.033 3.5 8.6 0.3 1 23 1223 1245 1223 1245 0.97

14 18 8.3e-05 0.0088 16.8 0.4 1 23 1251 1273 1251 1273 0.97

15 18 0.0049 0.52 11.2 2.6 1 23 1321 1343 1321 1343 0.97

16 18 0.00018 0.019 15.7 1.9 1 23 1349 1371 1349 1371 0.99

17 18 0.034 3.6 8.6 0.4 2 23 1466 1487 1465 1487 0.97

18 18 4.3 4.5e+02 2.0 0.3 2 23 1495 1516 1495 1516 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.77	82	4.3	0.1	1	23	88	113	88	113	0.92
2	18	1.4	1.4e+02	3.5	8.1	1	19	120	138	120	143	0.93
3	18	0.00086	0.092	13.6	0.2	2	23	159	180	159	181	0.95
4	18	7.1	7.5e+02	1.3	5.4	1	23	187	209	187	209	0.97
5	18	0.0053	0.56	11.1	0.7	2	23	215	236	214	236	0.97
6	18	0.0015	0.16	12.8	2.9	2	21	520	539	519	540	0.96
7	18	2.1	2.2e+02	2.9	1.0	1	23	608	630	608	630	0.82
8	18	0.017	1.8	9.5	0.2	1	23	846	868	846	868	0.94
9	18	0.009	0.96	10.4	0.2	1	23	876	898	876	898	0.98
10	18	0.24	26	5.9	2.4	2	23	988	1009	987	1009	0.95
11	18	5.7	6.1e+02	1.6	0.9	3	23	1021	1041	1020	1041	0.90
12	18	0.0029	0.31	11.9	0.2	1	23	1118	1140	1118	1140	0.98
13	18	0.033	3.5	8.6	0.3	1	23	1223	1245	1223	1245	0.97
14	18	8.3e-05	0.0088	16.8	0.4	1	23	1251	1273	1251	1273	0.97
15	18	0.0049	0.52	11.2	2.6	1	23	1321	1343	1321	1343	0.97
16	18	0.00018	0.019	15.7	1.9	1	23	1349	1371	1349	1371	0.99
17	18	0.034	3.6	8.6	0.4	2	23	1466	1487	1465	1487	0.97
18	18	4.3	4.5e+02	2.0	0.3	2	23	1495	1516	1495	1516	0.86

Sequence Information

Coding Sequence: ATGGCTGAACGCTCGCCACGACTGCGAGGATTGAGACCTCGTAATAAGCATCGTTCTCTGCAGAGGCAAACAGTCCCAAATGAAGTTTCCGAAGGAGAAGAAGCAGAAGACAGCGCCAATCGGAGCTCGAGCAGCAAAGATCAGAGTGTCGACGACTCAATGAATATGAGAAACGACAGCGATGACAATGAGCTTCATATCGAAATAAAGGATGAACAGGACGACGCTGCTTCGGATGATAAATCAGATACGGACAGAAATTATGAATGCAAGAACTGCAAGACTCCTGTAGGATTTCCAACCCTTGTGGAGTATCTTCGGCATCTTAGAGATGAACACAAAGAAAAGGGTCGAAGTTACGAGTGTCCGCACTGCGATTTCAAGTGCCAGCATCCGAAAAAATTGAAGGCGCATTGTGACTCCGATCACAAAGAATTGCACGAAGTTCCGACGTCCGAAGAATCGGTACCAAATACATGCACGATGTGTCCTTACATCGCGGCGAATGCGAGCGAGCTGGAAAATCACCAGCGCGTTCATCATCTCAAAAGACGATTTTTCCGGTGCACAAAGTGTTCTTACATGACTCACGTGAGAGCACGATACACGAAACACGTGAAATATCATTCTATGCCGATGATTAAGTGCCTCGACTGCGACTTTCGAACACCTTACAAGTGGAATTTGGACAGACACACGCGTAACCACGGCGGCGGCGGAACGTTTCAATGCAGAGCGTGCAATTTCACAGCAGATATTCGTCAGAGTCTGACTGTGCACGAGACGAATCATCACGAGCCGCCGGTTGGTCAATCAAACCGAAAACTGAACACACCTTTCGAGCGGAAACCGCGAAACGGTCCGAAGCGTTATAATCAGGTAGGAGCGAGCGATTTTCGAGATCTGCCGCATTCCGCGAGTCCTTTACCGGTGAATTCCAAGAGTCCAGTAACGTCGCCGATTTCCGACATAGCCGGAAGTTCTCTGGAGGACAGGAGAAGCGCCATCGCCGGCGCCGAGTGTATAGCGCTGAAATGCGAGGAAAAAGGCTGCCAGTTTATCACAGCCTGGGATTCGGAGATGCAACGTCACCTGGCGGAATCTCACGCGCCTTCAACTTCGCCCATCAGATCGAGAAAACCTCTGCCGATGCTTATTCCACTCAGTCCCGAGAGCAGCGCAAAACTGAAAAACACGCCGACGAACGGATCTTCGACGACGCTCCTCAAGGTTCCGCGGGTTCGAGTTCGACCGGAACTCGCTAAAATCGCGAGGGACACGGAAATGGCCAAGCTCTATGGAAACAAAGAGTCTAGCGGCACGAAAAAGGACACGGGGATCGGAGACTCTTTCGAGAAACGGAATGCCTCGTTCTTCGACAAGCTCAAGGAAAGATTGATGACTACGAGCGCGAGCATCGCGGGTGTGCCGCAAGTAGCCGTAAGTAGTGCGAACGATTTAAAGTGTTGGTGTACCTTCGAAGCGAGTAGCCCGGAGGAATTGGCCAGTCATAGTCAGACGCATCACACAGCACTGAGTGTATCCGTCGGGGTATCGCGCTGCCCTAAGTGTAGAAGGCGTTGTAAGAGTTCCACCGATCTTCAAATGCACATGAGACTTTGTCAAGCGTCGGTGAATGATTTAACGATGAGTGATAATTGTCCGGAGAGTCCAGCAAATAGTGCGAATTATACATCCGCCTCCTACAGTGGTGATTTTGAGTTTCCGTTTCAAGTGGACTGGGACGCGAGTTTTGGAGGCCTGAATTCTTCTGGATCGTCGGTCGAGGGAATTTCCGGCCACCCGCTCGGACGTCGGGTATTCAAGTGCCCCCATTGCCCATTCTGGGCCTCAACCGCCAGCAGATTTCACGTTCACATTGTCGGTCATTTGAATCGAAAGCCTTTCGAGTGTTCGCTCTGCGCGTACAGATCGAACTGGCGATGGGACATTACAAAGCACATCAAGCTCAAGGCGGCTAGAGATCCGGCTCACATGACCGCCAGGGTGCTTATGACTGACGAAACTGGCCGACGTAATTATTCCAAATACAACAAATATCTTGCTCAGGTCGAGCAGCAAGGAGCCGAGGAATCGGGTCTCGAAGAAGGACCCGCCGGAGAATCGCGGATCGACGAGCCACCAAAGAAAATTCTTATATTGAGCGACCCGAAGGAATATTCCGGAGGTCCTCCCGAACTTACGCCAGCGCCGGGCGTCGATCAAGCGGAAACACATTCCATGAGCATTCTCACGGCTCTGAACTTGAGGCCGCCACCCCCGCTAAAATCTGCTGCGAGGAGTCAAGGACAATCTTTGTTGAAGAATAGTCCGACCGCTTCTACAGCAGTTTCCATATTATCGACCTCGACGACTGTAGCCCCGACGGTGAACGCCGCCGATGAGACTAAACGCACTTTGTGGAAGTGCAAACGATGCAGCTTCCGGGATTCCAGCAAAGAAACCGTTTTGGCTCACGTTAAGTCTCATTACGATACGCTGGAGCACGCGAGTCCCGAAAACGATAAGACCGAATTCACGTGTCCCGACTGTCCGTACACGTCGAACGATCCAACTGCCATGGCTATACATCGCGTTCATCATCGTCCGAACCTCGAGGCCATTTTCAAATGTTACCTCTGTCCTTATTACGTCAGCACGAAAGCAGAATTACTGGAACACGCGAGACTTCACGGCGAGGAGTTAGCAGTGGTTCACCAGAGAAACATCGATTCTCTGTCTCCCACGAAGCAAAAGTCTCCTCAGGAGGTTCAATCGGACAATGAAACATCCTCGAAATCGGAAGTCGCAGTCGAGGAAATCGTGAGCCCAGTTCCACAAGCCACGGAAATCGTGAATCCGGAGGAAGTTGCACCGCCGTTATTACTAGACACTCGTGCCTTGCCCGACACGCCATTGGTGTGGGTTTCCCGTTCCGACGGAACCCTCGCTAAAATGCTCAAGTGTCGTCACTGCCCTCACGTATCCTCTCGCCGCGCCGAAGTTCGCGATCACGAAACGATGCACGTTAATTCGCCGACTTCCGGGCCTTTGGTGGCGTGTCGCGATTGCAGTTTCACGTGTTCGCGACGCGACATTATGGAAGCCCACGCGGATATGCACATGGGTTCATTGGGTACGGTTCATTGTCTCGTGGACGAGGGCCGCACGGACGCTCAGCAGTTGGAAGACCTAACGACGCTTCTCGGCCTCTCCAGAACACCGGCTCTCGGTCCTGAGCCCGACCTTCGAGACTCTCGTCTTGTGCATTGCTGCTCAAAATGTCCAGCGCGATTTCTCTGCGAGAAAGAGCTGCGGATTCACTTGCGTTATCATTCCACAGAACTAGCGTATTCTTGCCAATGGTGTTCATACGCCGCTCGCCAACCCGCGCATCTTCTGGCTCACCAAAAAGCACATTCCTCCGAATATCAGGATCGTACTCGCTATTTATTGTCGATTTACGGTCACTCCCAGCGATACGCGCCTCCGAACACGGCTTGCGTCGAATCGAACGATCGGCAGCCTCCGGACAATGCGCGAGGTGAAAGATCGACGAACCGATCAACGAACGTCGCTTGGATAGTCGTAGAAATCGTCGGAAATTCGTCTCAGAGCTGCTCCGCGAATCCGGAGAGCACCGAACAGCGAAACGGCAACCAGGTGTTCACTTGCGCCAAATGTCCAGCGCGTTACTTCAAGCTCGATGCGCTTGAGTATCACATGACGCTGCACGGATCTAACAACAGATTCAAGTGCGCGGAGTGCGATTATTCATCGAAAACGGCCCAGAATCTGATGAAGCATCAGGTGGTTCATCGTCGGCACGTTGAGGCGAGCGAACCTCCGGCCACGCGCGCACTTCCGCCTCCGGATCCTCAATTCGGGGTCAGTATGAGAGGCAATCCGAATTTCGTGTATCCGGGCTGTTTGAGAAACGGAAGGATGAAGGAAAAGCGTTACAAGTGCCATAAATGTCCTTCCGCTTTCGAGAAACGCGAACAATATCGCGTGCACCTTACGCTTCACGGTGCGAAGCAACGTTATCGCTGCGACAAATGCGATTATTCGGTTAAATATTATGCGAATTACGCTCAGCACATGAAAAAACATCAGGCAAATGCTCAGGCTCAAGCTTCCCGAAGACAATTCGAAGCCGAAGCTATTACCGTGGACAGCGACAGCGTCACGGAAACCGAAAGTCCCGATCCTCGGAGCTCGAAAAATCGGAGAAAATCTACGATATCCTCGGGCAACGCAGCGACGTACGAGAATGGTAACGCTGCTGGCTCGGCAGCAGCGTTGCAAGCTTCTAATCAAGACAAACAATCGGTTATGTTGATGCAGAAGAAAGGTGTTCCCGTAGCGCTTTCCGAGGCGAATAACAGACTGATGCGATGCCAGGATTGTCCGTTTTCCGGATCCGACAAAGAAGCGATGGACTCACACAGACGTCGTCACGGTATCGAGAGACTCACGCCCTCCTGTCCCCATTGCAATTACGTTCCTCGGAAAGACGAGAATGTCGGGGAACACATAAGATTGCATTTCACTAGACTCTACAAACCCGAGTCTTATCTCATCGTCGAGCTTCTTTCGCTCACAATGCGATCACTGTTTCCTGATAAGAAGGATCCGAAGTACAAGGAACCAGAGACGCTCTTCCGCGAATGTGCAGACGGAAACTACCTGCCGGTCACCGACTCTGCTCTTCAATCGCCCGCCGCCCCTTCCAACGCGAATGGCTATCAGGAAAAAGTAATTGTGGATCCGAACACAGGTGAGACGAAGCATCGTTATTCCGCATAA
Protein Sequence: MAERSPRLRGLRPRNKHRSLQRQTVPNEVSEGEEAEDSANRSSSSKDQSVDDSMNMRNDSDDNELHIEIKDEQDDAASDDKSDTDRNYECKNCKTPVGFPTLVEYLRHLRDEHKEKGRSYECPHCDFKCQHPKKLKAHCDSDHKELHEVPTSEESVPNTCTMCPYIAANASELENHQRVHHLKRRFFRCTKCSYMTHVRARYTKHVKYHSMPMIKCLDCDFRTPYKWNLDRHTRNHGGGGTFQCRACNFTADIRQSLTVHETNHHEPPVGQSNRKLNTPFERKPRNGPKRYNQVGASDFRDLPHSASPLPVNSKSPVTSPISDIAGSSLEDRRSAIAGAECIALKCEEKGCQFITAWDSEMQRHLAESHAPSTSPIRSRKPLPMLIPLSPESSAKLKNTPTNGSSTTLLKVPRVRVRPELAKIARDTEMAKLYGNKESSGTKKDTGIGDSFEKRNASFFDKLKERLMTTSASIAGVPQVAVSSANDLKCWCTFEASSPEELASHSQTHHTALSVSVGVSRCPKCRRRCKSSTDLQMHMRLCQASVNDLTMSDNCPESPANSANYTSASYSGDFEFPFQVDWDASFGGLNSSGSSVEGISGHPLGRRVFKCPHCPFWASTASRFHVHIVGHLNRKPFECSLCAYRSNWRWDITKHIKLKAARDPAHMTARVLMTDETGRRNYSKYNKYLAQVEQQGAEESGLEEGPAGESRIDEPPKKILILSDPKEYSGGPPELTPAPGVDQAETHSMSILTALNLRPPPPLKSAARSQGQSLLKNSPTASTAVSILSTSTTVAPTVNAADETKRTLWKCKRCSFRDSSKETVLAHVKSHYDTLEHASPENDKTEFTCPDCPYTSNDPTAMAIHRVHHRPNLEAIFKCYLCPYYVSTKAELLEHARLHGEELAVVHQRNIDSLSPTKQKSPQEVQSDNETSSKSEVAVEEIVSPVPQATEIVNPEEVAPPLLLDTRALPDTPLVWVSRSDGTLAKMLKCRHCPHVSSRRAEVRDHETMHVNSPTSGPLVACRDCSFTCSRRDIMEAHADMHMGSLGTVHCLVDEGRTDAQQLEDLTTLLGLSRTPALGPEPDLRDSRLVHCCSKCPARFLCEKELRIHLRYHSTELAYSCQWCSYAARQPAHLLAHQKAHSSEYQDRTRYLLSIYGHSQRYAPPNTACVESNDRQPPDNARGERSTNRSTNVAWIVVEIVGNSSQSCSANPESTEQRNGNQVFTCAKCPARYFKLDALEYHMTLHGSNNRFKCAECDYSSKTAQNLMKHQVVHRRHVEASEPPATRALPPPDPQFGVSMRGNPNFVYPGCLRNGRMKEKRYKCHKCPSAFEKREQYRVHLTLHGAKQRYRCDKCDYSVKYYANYAQHMKKHQANAQAQASRRQFEAEAITVDSDSVTETESPDPRSSKNRRKSTISSGNAATYENGNAAGSAAALQASNQDKQSVMLMQKKGVPVALSEANNRLMRCQDCPFSGSDKEAMDSHRRRHGIERLTPSCPHCNYVPRKDENVGEHIRLHFTRLYKPESYLIVELLSLTMRSLFPDKKDPKYKEPETLFRECADGNYLPVTDSALQSPAAPSNANGYQEKVIVDPNTGETKHRYSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00653182;
90% Identity: iTF_01497782;
80% Identity: -