Basic Information

Insect: Ephialtes manifestator
Gene Symbol: znf423
Assembly: GCA_963970395.1
Location: OZ019972.1:22974389-22996864[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 1e-05 0.0019 19.9 1.5 1 23 97 119 97 119 0.98

2 20 0.4 76 5.5 4.0 1 23 125 147 125 147 0.97

3 20 1.3e-06 0.00025 22.7 4.1 1 23 153 175 153 175 0.99

4 20 0.00027 0.052 15.4 0.2 1 23 181 203 181 203 0.99

5 20 0.0012 0.23 13.4 0.4 1 23 365 388 365 388 0.94

6 20 0.077 15 7.7 0.1 2 23 399 421 398 421 0.92

7 20 0.25 48 6.1 0.1 3 23 491 511 490 511 0.97

8 20 0.022 4.1 9.5 0.0 3 23 527 547 526 547 0.96

9 20 0.0032 0.61 12.1 0.5 1 23 556 579 556 579 0.92

10 20 4.6 8.7e+02 2.1 0.2 1 23 584 607 584 607 0.91

11 20 1.1 2.1e+02 4.1 2.1 2 23 681 702 681 702 0.96

12 20 0.0074 1.4 10.9 0.1 1 23 707 730 707 731 0.94

13 20 3.8 7.2e+02 2.4 0.7 1 23 798 822 798 822 0.86

14 20 0.00016 0.03 16.2 1.3 2 23 838 860 837 860 0.96

15 20 1.4 2.7e+02 3.7 0.7 1 12 869 880 869 892 0.76

16 20 5.5 1e+03 1.9 0.2 5 23 903 921 899 921 0.92

17 20 0.0043 0.82 11.7 0.2 2 23 1104 1126 1103 1126 0.95

18 20 0.052 9.9 8.3 0.4 1 23 1136 1159 1136 1159 0.96

19 20 0.0049 0.93 11.5 0.1 2 23 1202 1224 1201 1224 0.94

20 20 0.45 86 5.3 1.7 1 23 1231 1254 1231 1254 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	1e-05	0.0019	19.9	1.5	1	23	97	119	97	119	0.98
2	20	0.4	76	5.5	4.0	1	23	125	147	125	147	0.97
3	20	1.3e-06	0.00025	22.7	4.1	1	23	153	175	153	175	0.99
4	20	0.00027	0.052	15.4	0.2	1	23	181	203	181	203	0.99
5	20	0.0012	0.23	13.4	0.4	1	23	365	388	365	388	0.94
6	20	0.077	15	7.7	0.1	2	23	399	421	398	421	0.92
7	20	0.25	48	6.1	0.1	3	23	491	511	490	511	0.97
8	20	0.022	4.1	9.5	0.0	3	23	527	547	526	547	0.96
9	20	0.0032	0.61	12.1	0.5	1	23	556	579	556	579	0.92
10	20	4.6	8.7e+02	2.1	0.2	1	23	584	607	584	607	0.91
11	20	1.1	2.1e+02	4.1	2.1	2	23	681	702	681	702	0.96
12	20	0.0074	1.4	10.9	0.1	1	23	707	730	707	731	0.94
13	20	3.8	7.2e+02	2.4	0.7	1	23	798	822	798	822	0.86
14	20	0.00016	0.03	16.2	1.3	2	23	838	860	837	860	0.96
15	20	1.4	2.7e+02	3.7	0.7	1	12	869	880	869	892	0.76
16	20	5.5	1e+03	1.9	0.2	5	23	903	921	899	921	0.92
17	20	0.0043	0.82	11.7	0.2	2	23	1104	1126	1103	1126	0.95
18	20	0.052	9.9	8.3	0.4	1	23	1136	1159	1136	1159	0.96
19	20	0.0049	0.93	11.5	0.1	2	23	1202	1224	1201	1224	0.94
20	20	0.45	86	5.3	1.7	1	23	1231	1254	1231	1254	0.93

Sequence Information

Coding Sequence: ATGTTGTTCAAAGGCAACAGCTCGCGGCTGGAACTGCTTATTGGTAAAATCCAGGCGCACAAGGAATCACCATCACCACCGAGGGATGAGAAATGCAGTCCTAGAGCCAAAGATGCTTTGGGCACCGGCAGCTCATCTTGGCACAGCGAAGATGGTGGAACGAATTCTCGTCGTGGCGGGGAAACACCGTCGTCCTGTGCAACTCCAACGTCCGCAAGTTTTCCATCGGAACCCGAGGTTGACACCGAAATTGGCGTTAACGCCGATGGGAATAATCCCGCCGCGCCATATCCGTGCCAATTTTGCGACCGGACGTTTCCCAGACTTAGCTATTTGAAGAAACATGAACAGAGTCATGGCGATCAAATGCCGTACCGTTGCAACTGGTGCGCGAGGCTTTTCAAGCATAAACGCAGCAGGGATCGCCACGTCAAGCTACACACCGGAGACAGAAGATATCGGTGCTCCCATTGCGAGGCTGCCTTCTCCAGAAGCGATCATTTAAAGATCCACATGAAAACTCACGACAACCAAAAGCCTTATCAGTGCACAGCCTGTTCGCGTGGTTACAACACAGCGGCAGCTTTGACATCGCACATGCAGTCGCACAAAAAGCATCAGAGTCCAGGACAAAATACAAAACTAGAAATGGACTATGGTCGTCGAAGTGTGTCGTCGCACAGCACGTCATCGCCGCCAATCGGAAACTCTCCATCTCCCAGTTTGAACCTAAGTCTACATCCAAAAAGTTCATTAAAATCAACCTACCTCAACAGTAACGGTACAGCAGCAAATGCACCCCTTGTAAATTCACCGTTGAAACTCGCGTGCATGTATTGCACCAGAGACTCCTTCACGAGTATGCAACAGTTGCAAATGCACGTGCACGCGATGCATCAGGCGATTTTGAACGGCGAAAGTTTGACGATGGCTTCACCGACACGAACCCAATCGGATGGAAAAAACTATGCAAAATCTCAAGATCACGAAAAGGTGgagaaaaatagtagaaaagaCTACGAAATGACGTATCGCCTCGAAGATCCGGAAAAATCTGTGGAAAGAGCCAAAGGAGATTCGTTAGAAAACGAATTTAGCTGCGGTCAATGTACAATGAAATTCTCGAACGTTAGCTCGCTGCGAGATCATTTAGTGTCGATACACCGAAACGATGGATTCGGCGCGAGTTTGATGATGTGTCCTCTGTGCGGAATTCCATGCACATCAGCCGCCGCTTATGCCGAACATTATTTGCTCCGACATTGCGAGAATCGTCGGATAACTTCGAAAGATCCGACACGTCGCGATTGGGAGGACACGACAGCAAATGGAATACACGAGGACAGCCAACCGCCTACGAAGACTCAAAGTTTTATAAGCAGATCCGAGATTGCTTCGTCGGAACCTGCGGATTTAACGAAAAAGCATACAAGACCAGGAGATTCGAGTTACTCGGCTGGTACTTTGCTGTGTGGTCAATGCGGAGCCGCCCTCAAAGACTTCGAATCATTTCGGGAACATCTAGCTAGACATTTGCAGGCTGATCAACAGAATAGCGAAGTTGTACCGATAAATCCTTGTCCAAAGTGCGACGCCAACTTTCCAGAACGCGAGGACATGTTGGCTCATCTAACGAAGCACTATCTTGGACAGATGACCAAAGAATACGCATGCGGTGCTTGCAAAAAGTTTTATCCTCATCCGGATCTCCTGCAGCGACATCTTCTTGACACTCACGCTCATCATCTCTACAGATGCGCCTTATGTCGAGATACTTTCGACTCCAGAGTCGCTATACAAGTTCATTTCGCTGTTAAACATAGCCAAGAATGTCGGATTTATCGGTGCAGCACTTGCAGCGGTTCCAACAATGAGAATTCACCGGGTAATAGTTCTGGGGAAGGCAAAAGCTACTTTCGAAGCGAAACCGAAATGGCGAATCATGTTAGAACTGTTCACGCTCCACCGAATGCACTTGCTAATGAAGGTCCATCACCAAAAAGTCGAGCATCTACACCTGGTCCTAATTTGGCCACACCTAGATGCGTTTTTTGCGGCATTTGCTGCAACTCGGACTTGGAACTGCAACTTCATTTGGCTAGCCATTCTAGCAGCTTGTATCGGTGTCCAATATGCAGAGAGGGATTTCCCGTGGAATTTTTACTCGACAGGCATATAGCGCAGGCGCATCATGCCAATAACGAGAGAAGTGATGCTGGGGAAAATGGACGGACGCATAGAACCTCGCGATTGGGGGAGGAGACGGCGAGGCCACAAAAGCGAGGAAGATCGCCAGCTTCCAGCAACAACAATTCCTTAAACCAGCGCGACAACAACAACAAGAGACTAAATTACGGCACGACAAATGGCACAACAATGGTACGAGGTGGTCATCGATGCGAGCTCTGTGAGCACGGCGAATTTGCGACGGAAGCGGAATTGCAAGCGCACAAAAAATTAGTCCACACGCCGGTGAAGCTGCAGGCCAAGTCGCTGTCGTCACTTAGCATGACATGTGCTTACTGCGGTGAGATTTGTCGTTCACGAAGCGAGCTCGAGTCTCACACGAGAATGCAGCATGCTTCTAACGAGCCTGGCGGACGGCACAAGTGTAACATTTGCGACGAGGTTTGTCCGTCGGGTGGAATATTGGCCGAGCACAAGCTTCAGAAACATTGCAAGATTCAGTTGAGCGACAACTGCATTGTTTGCCGCACAACGCTTACAAGCGAGGCTCAATTCGTGGAACATGTGCAACGTCACAGCCTTGAAAGTGCCGACCCTCAGCAAAGATTAGAAAATGCGCTTCCTCACCTTCCGGCAGGTTGCGTTGTGTGCCGACAAACACTAATAAGCGATCTTGAGTGTCGACTACACGCAAGACATCATCTACGAGCTTCCAATAGCTTGCAGAATTTAACTTCAAGTCCCAGTCCAATCCACCACAAGAgccaacaacaacagcagccgcaacagcagcaacaacttCAACGTCCAACTCTCAGCTGTTGTCTCTGTTTGAGAGAATTTACCGCCGATGATTTTGTCAGTCTTCCGTCGAATCCCTCTGGCACCGCGGGACCTTCATTGAGAGTCTGCAAACCTTGCTACGTAAGACACTCGCAAGGACTGCCGATTCTTAACTCACCTTATGAACACGTTAGGCCATCCAAGAGTGAAACTATGCTGTGGCCCACTGCTAAAGATCAGACCAATTGGGATAGCTCCAGAGATCACTGGGACAACGAAAGATGTTACAAAGCTGATGAGAGTGTCAAAACGGGAATTGAGGACAATTCCGATGACAAGAGGTGCGAGGAGTGTggcattaaatttgaaaattctgacGAAGCCGAGAGTCATAGGATCAAGGAACATGAGACTAATTGCGGAAGTGCCAACATCTATACATGCATACAGTGCCAGATGTCCTTCCCAACTGAGGATAAAATTCAGCAGCACGTGAGGAAAGAACACTTGGAGTCCCCTAACCAAGCATCCATAGAAGCACTGCGCTGTCATCTCTGTCTCTTTGAAGCCAACAGTCCCCTTCAACTCCAGGGACACTTGATAGAGCATACGTTCGCCGGGTGCGCTGGTCTCACTTGCTACATATGCCAGGCACTTTTTACTACCCCCATCGCGCTGCAGAATCACATGCTTCAGCAGCATGGGTTGGGTGCTCGTCCCTACGATTGCAGTAACTGCAATCTAAAATTCTTTTTCCGCATTGAATTGGACCATCACACGGTAATGGTGCATCGAAGAACCGAAACATCTTCGCCTCCCGTAGACGTAGGACAGGAAACTGCAACGGAAAAGCGAGAAAAAACTACGGATAATAGAGCCGGCGACGATCAGCATCGTTTGGAGAATGTGACGGTAAAAGAAGAAATTGCGAATAGTCTGGAAGACGAGGATATCAACGTGGATGGTCACGTTGATCAGTCAACCGATCTCGAGTCAAAGCATGAACAGTGTCCTTTGGTAGACGCGAAAAAAGAACCGTTCACTGTACCGCGTGCGATGGAAGAGAAAACCGTCTCCTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKESPSPPRDEKCSPRAKDALGTGSSSWHSEDGGTNSRRGGETPSSCATPTSASFPSEPEVDTEIGVNADGNNPAAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCNWCARLFKHKRSRDRHVKLHTGDRRYRCSHCEAAFSRSDHLKIHMKTHDNQKPYQCTACSRGYNTAAALTSHMQSHKKHQSPGQNTKLEMDYGRRSVSSHSTSSPPIGNSPSPSLNLSLHPKSSLKSTYLNSNGTAANAPLVNSPLKLACMYCTRDSFTSMQQLQMHVHAMHQAILNGESLTMASPTRTQSDGKNYAKSQDHEKVEKNSRKDYEMTYRLEDPEKSVERAKGDSLENEFSCGQCTMKFSNVSSLRDHLVSIHRNDGFGASLMMCPLCGIPCTSAAAYAEHYLLRHCENRRITSKDPTRRDWEDTTANGIHEDSQPPTKTQSFISRSEIASSEPADLTKKHTRPGDSSYSAGTLLCGQCGAALKDFESFREHLARHLQADQQNSEVVPINPCPKCDANFPEREDMLAHLTKHYLGQMTKEYACGACKKFYPHPDLLQRHLLDTHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCSTCSGSNNENSPGNSSGEGKSYFRSETEMANHVRTVHAPPNALANEGPSPKSRASTPGPNLATPRCVFCGICCNSDLELQLHLASHSSSLYRCPICREGFPVEFLLDRHIAQAHHANNERSDAGENGRTHRTSRLGEETARPQKRGRSPASSNNNSLNQRDNNNKRLNYGTTNGTTMVRGGHRCELCEHGEFATEAELQAHKKLVHTPVKLQAKSLSSLSMTCAYCGEICRSRSELESHTRMQHASNEPGGRHKCNICDEVCPSGGILAEHKLQKHCKIQLSDNCIVCRTTLTSEAQFVEHVQRHSLESADPQQRLENALPHLPAGCVVCRQTLISDLECRLHARHHLRASNSLQNLTSSPSPIHHKSQQQQQPQQQQQLQRPTLSCCLCLREFTADDFVSLPSNPSGTAGPSLRVCKPCYVRHSQGLPILNSPYEHVRPSKSETMLWPTAKDQTNWDSSRDHWDNERCYKADESVKTGIEDNSDDKRCEECGIKFENSDEAESHRIKEHETNCGSANIYTCIQCQMSFPTEDKIQQHVRKEHLESPNQASIEALRCHLCLFEANSPLQLQGHLIEHTFAGCAGLTCYICQALFTTPIALQNHMLQQHGLGARPYDCSNCNLKFFFRIELDHHTVMVHRRTETSSPPVDVGQETATEKREKTTDNRAGDDQHRLENVTVKEEIANSLEDEDINVDGHVDQSTDLESKHEQCPLVDAKKEPFTVPRAMEEKTVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00343389;
90% Identity: iTF_01497703;
80% Identity: -