Eman037512.1
Basic Information
- Insect
- Ephialtes manifestator
- Gene Symbol
- -
- Assembly
- GCA_963970395.1
- Location
- OZ019979.1:4287423-4300393[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 21 5.5 1e+03 1.9 4.3 2 23 232 254 231 254 0.96 2 21 0.64 1.2e+02 4.8 5.1 1 23 325 347 325 347 0.97 3 21 0.012 2.3 10.2 0.5 1 23 396 418 396 418 0.98 4 21 1.3 2.4e+02 3.9 0.6 1 20 479 498 479 500 0.91 5 21 1 1.9e+02 4.2 0.6 1 10 512 521 512 535 0.88 6 21 7.4 1.4e+03 1.5 2.6 3 23 542 562 540 562 0.96 7 21 0.55 1e+02 5.0 0.0 1 23 610 633 610 633 0.93 8 21 9.4e-05 0.018 16.9 0.0 1 23 639 661 639 661 0.96 9 21 1.7e-07 3.2e-05 25.5 1.0 2 23 699 721 698 721 0.97 10 21 0.019 3.6 9.6 0.3 1 23 727 750 727 750 0.93 11 21 0.0043 0.81 11.7 0.1 3 23 759 780 757 780 0.95 12 21 0.00021 0.039 15.8 0.6 3 23 790 810 788 810 0.92 13 21 0.046 8.6 8.4 0.1 2 20 885 903 884 903 0.95 14 21 0.051 9.7 8.3 0.0 2 23 923 944 922 944 0.96 15 21 2.3e-06 0.00044 21.9 0.9 2 23 961 982 960 982 0.97 16 21 1.7e-05 0.0031 19.3 1.8 1 23 1005 1028 1005 1028 0.95 17 21 3.5 6.7e+02 2.5 0.1 2 23 1089 1111 1088 1111 0.94 18 21 0.015 2.9 9.9 0.6 2 23 1139 1161 1138 1161 0.92 19 21 1.4 2.7e+02 3.7 0.1 1 23 1169 1193 1169 1193 0.97 20 21 1.8 3.3e+02 3.4 1.3 1 23 1198 1221 1198 1221 0.94 21 21 0.11 21 7.2 0.2 2 23 1252 1274 1252 1274 0.96
Sequence Information
- Coding Sequence
- ATGGACAATGTTTTCAACGTTCAAAATCCCGAAAACGTGTGTAGATTGTGCCTTTCAACGGAGGAACCAATATCCTCGGTATTCGACGATCAAGCAACCGCCGTTTCGTTAGCTACGAAAATTCAATCTTCCTTGTCAATCGAGataCAAATCAGCGACAAAGTGTCGACTTTGATATGTGGGAATTGTCTTAAGAGAGTCAACGAATGGCATACGTACAAAGAAGCTTGTTTACGATCACAGGAAAAACTGCAACGATGCTTCAGGGAACGGATGGAAACTATTCCAAATATCAAGATGGAACCAATGGACGTAGAGGATCCGATAGAAACTTTGGAGACAGTTCCCTTAACATCGGACGAAGAATGGGAGGATTTACCGGATCTCCCGGTAAATGCTTGTCTGACAAATATATGCGTCGACCTGCCAAGAAACGGCGAACTCCGAGACaacacaacaataaaaaaagagcTTATGGAGGACGAGGAAAACAACGCGAATGCCGAAATCGATTCCGTCTGTAGCCGAGAATTGCTGTTAAATCCCATGGCAATGGCAGGAAGTAAAGAGGACAGAGTAATGGAAGCGGATTCAACGCAAAAGTATCTCAAAGTCAAAAATCTTCGTCCCGGCAAGAAAAAACCTCGTCGTGGTCCTAAAACTCATTACACGGGCCCACGAAGATACAAACAGCGTTGTTCATTCTGCCAGATTTATCTGCACTCGAAATTCACTTACGCTAAGCATATGCAACGTTTTCACGGTGGCGCAGCGCCGCAAAGAAAATCAAGAACAAAGCGTGAAATcttggataaaaaaatgtctaatcaAGCGAATCGCGCCGCCTATGAAGAAGATGTTGAAGAAGTCACTGAAGAAATGGTCGAGGATGTTGAGGACGAATTAATAAGCCTAGAAAAAGATGCACCGCTTACGCCAGTTCAGCAAAATATAATAAgccaattaaaaacattttcctGCTATTCCTGTCAGCAATGCTTTCAGGATCGTCGCAGCACGCTTAATCATATACGTCAACACATGCCGGACTTAAGGCCTTACACTTGTATCGCTTGTCTCACCGAATTTGCCGATCGTTCGATTTACAAACTTCATTGCGGCGCGTCTTTTCAATGCGCCATGAAAATAGCTCTCGTTGTGCCGGAACACGGAacggaaaaatattttacatgcaATATGTGCCTCAGGCCTTTGGCTAATCGTAAGGAACTTCTTAGCCATTTGTCGAAACATTCGGACAAGCAATACGAGCAAATGATCGCCGAGCCTTTCCGTTCGCCTCCGAAATTAAAGCCAATGACGCCTTTGACCTCATCGCCTGTTAAAAATCGCGGTAAAAATCTTTCGAATCCAACGAGTCCCGTCGCAAGAATTTCCAAAGCTCCTTATCAAAACGGCGATCCCGCTTATAATCACACGTGCATTCACTGCGGAATGATCTACAGATACAAGCTAAATATGCTTAAGCACGTGGAATTGTGCAAAAAAACGCCTCAGATCGACCGCGTGAGTTATCGATGTTTTCATTGTGGTTTAACGTTTCTCGCTCTTAAGAGATTTTACTCTCACTTAAGTGCCGAACATAAAACCCGAGATATCGCGTGTTTCCACTGCAAATCAAAGTTCCAAGACCTTAACGTTTATTCCGAACATTACAGAAAACATCGCATTAATCACGCGAAAACAATCGTCGCGCTGGAGAAAAGTCCAGAAAAAGAACGTCCTTCAAAAGGTAAAATTTCAAGCGGCGTTaatcagaaacaaaaaaataccacGAGCAAAACGAGTATCAAGAATTCCGCTGCATTTAGCTGCGCAATTTGTCCCGGCAGCGCTTTTGCAACGAGAAATCTATTGGCTGAACACAGAAAAATTCATCTCAAAATGAAGATCTATTCCTGCGCTATTTGTCGAAGAATGTTCGGCAGAGCTTCCGCTTTGGAAGCTCATATGGCTGATCACGAAATGGACGTTCCTCTCAGCGCATTAGATCCAAATAGTACGATTCCCTTGATGGATCGTGAAGAAAAGATGAATTTCTCGATGAATTCCGATCCTGGAACTAGCAACACCGAATGTCACACTTGCGGCAAAGTTTTCGCTAATTATCCGAATCTCCGACGACATATACGCACTGTTCACGACACAATAGGACGTTACAGTTGTTTTACATGCGCGAAAACATTCAAGAGCGAAGAACAATGGGCGGATCACGTGGAAAACGAGCACAATCATTTGGAGCCTACGATAAATTGTCCCCAGTGTCCCGAAGAATTTGATACCGATCAGTCGTTGGAGATTCATCGAAGAAACGTTCACGGTATAAACGGCGAGGATCATCTTGCTTGTTACATCTGCGGTAAAAATTTCGCCAATGAATCGTCATTGAGAATTCATCGTGGTCATCATTTTCGTGTTAATTCGAGGCTTAGCATTGGAAATCGTCAGCAAAATGAGCCACGCGAGGAAAAACTACGAATTGGTGGTTCGATTTCGATTGGCAAAGATTCTACGACGATTCACAATCACAACGACGACGATACTGTCGTTAATCCGTCGCCTGTTAAATCACCGAGAGCGAGGAAATCATTTCCCAATTCGAGCCCCGTAAAACAGTTGCAAAATATATTACAGTGTCAAGTTTGCGACGATCGTTTTCCTGATGTTTCGACACTACGTAAACATCTTTGGGACGTTCATTGCGCTCGTAATAAACCAGAAAAAGCCTTTGCCACTGAGAAACTTCAGTGCGAATTATGCACGAACGTTTTGCCTGACGAAGAGAGCCTCGCGAGTCACATGAAGTGGCACGAAAATAATCCAATATTAAGCAACGGTGGTAAACGCGATACGCCAATGGAATGCGATATTTGCGGCAAATTTTACAGCTCAAAGGGAAATCTTTGGAAGCATAAAAAACGACACAAAGCGAGAAACGTAGCGGCGTTAAAAATGCAACCAGTACCCAATCACAATTGGGGAGGACGTGGCTTTTCTTGTAACACGTGTCGAAAAGTTTTTGCCACAAGATCGACGcttaaaaaacacaaaatttcgGCTCACATGCAATCGCAAAATCGTGCGCAATCCGCAAATGCAACGGCAAAACGATTGTTGGCTGGTAATTCTAAAGAGACGCAGAAAATAAAACCTATGAGACCGAAACTCGATTTTGATACGCTCGTACAACAAGCCGATTTTACCGACGCTGAATTGTCGAATAGCAACTCGAAAAAACCTGTGACTTGCGCTTTGTGCAGAAAAATCGTGCCTGGAATGCGAGCGCTTTATAAACATCGTCAGGTCGTTCACAAAATAATAATCGGTAAAACGGCATCGAAGCCGGAGATGAAAATTTTGGCTTCTATGAAAGCGGAAAAAGGAACTGAAGTTAGCTGCACTGCTTGCTCCAAAGTTTTCTCCAATCTTCCAAATATGAGGCAACACTTTACGAAAGTTCATGGACCGAATAGCAGCACGGAATTTCGATGCACTGTCGAGGGATGTAAAATTGTGTTAAAGAGTCTCGCTGCTCGACTAAATCATGAAAAAACGCATGTTAACGTTATGTACACCTGCTCGTTGTGTCCGAGACATATGCTGAATCGTGAAGCTATGGCTCATCATATGCTAACAGCCCACAAGAGTAATTATGCAACGGGAAACAGCAAAAtgatgctttgtaaaaaaatcaatctcgACAATTACACGGTTAAAGGAGCAATTGGACGTGAATGTCCTGTGTGTAAAGTGAATTATCCCAATTTCAAATCGATGAAGATACACTACCTCAAAGTACACGAGGGAGCAGCTTAA
- Protein Sequence
- MDNVFNVQNPENVCRLCLSTEEPISSVFDDQATAVSLATKIQSSLSIEIQISDKVSTLICGNCLKRVNEWHTYKEACLRSQEKLQRCFRERMETIPNIKMEPMDVEDPIETLETVPLTSDEEWEDLPDLPVNACLTNICVDLPRNGELRDNTTIKKELMEDEENNANAEIDSVCSRELLLNPMAMAGSKEDRVMEADSTQKYLKVKNLRPGKKKPRRGPKTHYTGPRRYKQRCSFCQIYLHSKFTYAKHMQRFHGGAAPQRKSRTKREILDKKMSNQANRAAYEEDVEEVTEEMVEDVEDELISLEKDAPLTPVQQNIISQLKTFSCYSCQQCFQDRRSTLNHIRQHMPDLRPYTCIACLTEFADRSIYKLHCGASFQCAMKIALVVPEHGTEKYFTCNMCLRPLANRKELLSHLSKHSDKQYEQMIAEPFRSPPKLKPMTPLTSSPVKNRGKNLSNPTSPVARISKAPYQNGDPAYNHTCIHCGMIYRYKLNMLKHVELCKKTPQIDRVSYRCFHCGLTFLALKRFYSHLSAEHKTRDIACFHCKSKFQDLNVYSEHYRKHRINHAKTIVALEKSPEKERPSKGKISSGVNQKQKNTTSKTSIKNSAAFSCAICPGSAFATRNLLAEHRKIHLKMKIYSCAICRRMFGRASALEAHMADHEMDVPLSALDPNSTIPLMDREEKMNFSMNSDPGTSNTECHTCGKVFANYPNLRRHIRTVHDTIGRYSCFTCAKTFKSEEQWADHVENEHNHLEPTINCPQCPEEFDTDQSLEIHRRNVHGINGEDHLACYICGKNFANESSLRIHRGHHFRVNSRLSIGNRQQNEPREEKLRIGGSISIGKDSTTIHNHNDDDTVVNPSPVKSPRARKSFPNSSPVKQLQNILQCQVCDDRFPDVSTLRKHLWDVHCARNKPEKAFATEKLQCELCTNVLPDEESLASHMKWHENNPILSNGGKRDTPMECDICGKFYSSKGNLWKHKKRHKARNVAALKMQPVPNHNWGGRGFSCNTCRKVFATRSTLKKHKISAHMQSQNRAQSANATAKRLLAGNSKETQKIKPMRPKLDFDTLVQQADFTDAELSNSNSKKPVTCALCRKIVPGMRALYKHRQVVHKIIIGKTASKPEMKILASMKAEKGTEVSCTACSKVFSNLPNMRQHFTKVHGPNSSTEFRCTVEGCKIVLKSLAARLNHEKTHVNVMYTCSLCPRHMLNREAMAHHMLTAHKSNYATGNSKMMLCKKINLDNYTVKGAIGRECPVCKVNYPNFKSMKIHYLKVHEGAA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01497663;
- 90% Identity
- -
- 80% Identity
- -