Basic Information

Insect: Ephestia elutella
Gene Symbol: -
Assembly: GCA_018467065.1
Location: CM031583.1:4731284-4760635[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 1e-10 6e-07 30.5 0.1 7 48 288 331 283 333 0.87

2 7 8.1e-12 4.8e-08 34.0 0.1 7 50 336 381 330 384 0.86

3 7 1e-10 6e-07 30.5 0.1 7 48 443 486 438 488 0.87

4 7 8.1e-12 4.8e-08 34.0 0.1 7 50 491 536 485 539 0.86

5 7 9.7e-12 5.9e-08 33.8 0.0 7 50 598 643 593 647 0.88

6 7 9.7e-12 5.9e-08 33.8 0.0 7 50 705 750 700 754 0.88

7 7 1e-14 6.1e-11 43.3 0.0 7 70 812 873 807 878 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	1e-10	6e-07	30.5	0.1	7	48	288	331	283	333	0.87
2	7	8.1e-12	4.8e-08	34.0	0.1	7	50	336	381	330	384	0.86
3	7	1e-10	6e-07	30.5	0.1	7	48	443	486	438	488	0.87
4	7	8.1e-12	4.8e-08	34.0	0.1	7	50	491	536	485	539	0.86
5	7	9.7e-12	5.9e-08	33.8	0.0	7	50	598	643	593	647	0.88
6	7	9.7e-12	5.9e-08	33.8	0.0	7	50	705	750	700	754	0.88
7	7	1e-14	6.1e-11	43.3	0.0	7	70	812	873	807	878	0.89

Sequence Information

Coding Sequence: ATGTCGGAGGAAATGGCGATTGGTGATAACGCTACTAGCGAAGAAACTAAGTTGAATGGCGATGAGGCGTCGGCTGCGAGCGCCGTTGATACTGACGCGGCCGCCCCGGAGCCCCAGGCTGAGCCCGAAGCTCCTCCAGTTGAGGACGCGCCAGCACTCGCAGAAGAGGTACCAGAAGTGAAAGAGGAGATAGCCGAGGATGTTAACATGGCGGAGCCTGAACAACCATCAGACAAGCTTGTCGCAGGAGATGGCATTGACGAGGGAGATGAGAAGAGAGGCGTCAAGCGGAGAGCCTCCGCAGCCTTCAGCGATGCGGGGAAAGAGGACTTTAAAGGCTTTGAGACGGGTGAAAGTGAATTTGAGTCGTCATACAGTGAAGTGTACAGTCGGATTGTTGACCGCTTGGAAGCGGAAGTGTCAGCGGCCGTCAAGGACCTCACGCCAGTCCGGTCCGTGATGGCCACTCCGTCCGCCCCGCTGCGGGCCAGCAAACGCCCGCGACAGGACACCGGTGAGAAACTAGCCTTAGATTCCCTCGATAAGGAGTTGTTGGAGGCCGTTAGAGATATGGATAGCTCTGAGAGTAAAATAGTTAAGAAGCGTCCGTCGCGGGCGGTGGATGTGGGCGACAAGCGCCGCGTCATCCCCCGCCCaccgcggcgggcggcgcgccaCGACCGAGATGTCCTCCCCCCTCCTGCGGCTGCCGCTGGAGCGCGGCTGGAAGCGGGAGCTGGTGTACCGCGCGGCGCTGGACGCGCACTCGCGACGCAACGCCGATATATACTACTACACGCCCAAGGGGAGGAAGCTGAGGTCCACCAGGGAGGTCAGTGCCTGTACAGCAACCTCCCCCTCCTGCGGCTGCCGCTGGAGCGCGGCTGGAAGCGGGAGCTGGTGTACCGCGCGGCGCTGGACGCGCACTCGCGACGCAACGCCGATATATACTACTACACGCCCAAGGGGAGGAAGCTGAGGTCCACCAGGGAGCAACCTCCCCTCCTGCGGCTGCCGCTGGAGCGCGGCTGGAAGCGGGAGCTGGTGTACCGCGCGGCGCTGGACGCGCACTCGCGACGCAACGCCGATATATACTACTACACGCCCAAGGGGAGGAAGCTGAGGTCCACCAGGGAGGTCAGTGCCTGTACAGCAACCTCCCCTCCTGCGGCTGCCGCTGGAGCGCGGCTGGAAGCGGGAGCTGGTGTACCGCGCGGCGCTGGACGCGCACTCGCGACGCAACGCCGATATATACTACTACACGCCCAAGGGGAGGAAGCTGAGGTCCACCAGGGAGGTCAGTGCCTGTACAGCAACCTCCCCCTCCTGCGGCTGCCGCTGGAGCGCGGCTGGAAGCGGGAGCTGGTGTACCGCGCGGCGCTGGACGCGCACTCGCGACGCAACGCCGATATATACTACTACACGCCCAAGGGGAGGAAGCTGAGGTCCACCAGGGAGCAACCTCCCCTCCTGCGGCTGCCGCTGGAGCGCGGCTGGAAGCGGGAGCTGGTGTACCGCGCGGCGCTGGACGCGCACTCGCGACGCAACGCCGATATATACTACTACACGCCCAAGGGGAGGAAGCTGAGGTCCACCAGGGAGGTCAGTGCCTGTACAGCAACCTCCCCTCCTGCGGCTGCCGCTGGAGCGCGGCTGGAAGCGGGAGCTGGTGTACCGCGCGGCGCTGGACGCGCACTCGCGACGCAACGCCGATATATACTACTACACGCCCAAGGGGAGGAAGCTGAGGTCCACCAGGGAGGTCAGTGCCTGTACAGCAACCTCCCCCTCCTGCGGCTGCCGCTGGAGCGCGGCTGGAAGCGGGAGCTGGTGTACCGCGCGGCGCTGGACGCGCACTCGCGACGCAACGCCGATATATACTACTACACGCCCAAGGGGAGGAAGCTGAGGTCCACCAGGGAGGTCAGTGCCTGTACAGCAACCTCCCCTCCTGCGGCTGCCGCTGGAGCGCGGCTGGAAGCGGGAGCTGGTGTACCGCGCGGCGCTGGACGCGCACTCGCGACGCAACGCCGATATATACTACTACACGCCCAAGGGGAGGAAGCTGAGGTCCACCAGGGAGGTCAGTGCCTGTACAGCAACCTCCCCCTCCTGCGGCTGCCGCTGGAGCGCGGCTGGAAGCGGGAGCTGGTGTACCGCGCGGCGCTGGACGCGCACTCGCGACGCAACGCCGATATATACTACTACACGCCCAAGGGGAGGAAGCTGAGGTCCACCAGGGAGGTCAGTGCCTGTACAGCAACCTCCCCTCCTGCGGCTGCCGCTGGAGCGCGGCTGGAAGCGGGAGCTGGTGTACCGCGCGGCGCTGGACGCGCACTCGCGACGCAACGCCGATATATACTACTACACGCCCAAGGGGAGGAAGCTGAGGTCCACCAGGGAGGTCAGTGCCTGTACAGCAACCTCCCCCTCCTGCGGCTGCCGCTGGAGCGCGGCTGGAAGCGGGAGCTGGTGTACCGCGCGGCGCTGGACGCGCACTCGCGACGCAACGCCGATATATACTACTACACGCCCAAGGGGAGGAAGCTGAGGTCCACCAGGGAGGTGTCGGAGCACCTGTCTGGCACAGGGCTGACTCTGGAAAACTTTTCATTCTTCAAAGAGCCCCTCGGGCTGGACGATCCTGAGAAGGAGATTATTCGaGACGCAAAGATGATCCGTCGCGTGGAGTCCCCGGTAGTGGCACAGCCACCGACCGCGGAGGGCAAGCGCACGCCCAAGCCCAAGCCGCCCAAAGGTGCAAGTCCTGAGCCCAAGCCACCAGCCACTGTCAAGTCCCCGCCTGCTAAGATCAGGGGCAAGCGCTCGCCCAAGCCGCCCAAAGGCGCAAGTCCTGAGCCCAAGCCACCAGCCACTGTCAAGTCCCCGCCTGCTAAGATCAGGGGCAAGCGCTCGCCCAAGCCCAAGCCGCCCAAAGGCGCAAGTCCTGAGCCCAAGCCACCAGCCACTGTCAAGTCCCCGCCTGCAAAAATCAGGGTGAAGTCAGTAGGGTCCAGACTTAGCACCAGTTCGCCTGCCACGCCAGCTGCCAACACCAACACGAAACAACAGAAGAAGCCGGCCGACAACAACAATAGCGCCGCTTGGAAGAAGCCCAGACCGCTCGTCGCGCCGCCGGTCGCGCCGCCAGTCGCACCGCCGGTCGCGCCGCCCGTGGTGACGCCGGTGGCGCCGCCGCGGCCCGCCacgccgccgcagccgccgccccCGCTGCAGAGCCGGCCTCCGCCCTCGCCTGACGTCACGTCGCCCCGGCAACTAGTACAGCCGTGCTCAATGACCTGCGGCCGCGGCTTGCCCACGGTGGCCTGCGCGGCCTGCTTGTGCCTGTACCACCCCGCGTGCATCGGGTACAACCATACAGCCACGGGCAGAGTGCTCTGCAAGAACTGCCGCTCCTCGCCGCCCCCCCTCGAGCCGCCCCCCCTCACCCACAAGTCTGGGGTCAGCGGGTCCAGCATACCCGCGcccgtgcccagaaggctgccGGGGCCGCTGCCGGTGCCTGTACCGGTGCCAGTGTCTAAGATACGACCGGATAAACGAGTGACCTTGAGAATGAAGGTGGCGGGTGGTGGCCCCGATGGGGAGCGGGTGTGGGCCGTGGCCCCGCAGCAACCGCCCCGCGCAGTGCTGCTGCGGGCACAGCTGCCGCAGTCGGTGGCCGTACTCAACGGACGACGGTTCATTGTTGTGCCGAGGGAGATACGAGCTCCTAATGAAGACAAGAAGCGCGGTAGAGTGGCCAATGGCGCGGCGTCCCCGCCGGCCGTGATGACGTCACCACGCAGACGCGGCCGCCCGAAGATAGATGATACAGATCATTTCACAACGTTCTATAACACGGCGCAGGAGAAGAACTACAATGTTGTTGTACAGATCTTCCAATACCTGGGCATGCGGGACCTGGCACACTCAGCTCGCGTGTGCAAGCTGTGGCGGCAGCTGGCGGCCACGCCGGCGCTGTGGAGGCATGTGCGGATGAAGAACTCTCACGTGAGTGACTGGGGCGGACTGTGTGCAGCTCTGAAGCGCCACGGCACCAAACGGCTGGATCTACGCAAGATGTTGCTGCCACAGAATGATACTACCTTCTGGGACCAGTTCGCGCACCATATAGGGGAGGTGGACTCTTTGGAAAGGATAGAAATGTGTCGCTGCCCCGCGCGCGCAGTAGAAGCAGTATGCGCGTGCCTGCCTTCCTTACGCGCACTATCCGCGCTCGCGATAAAAGACGCACGACTGGACCCTGAACCGCTGTCCAGACTGACGCTGCTGCACGAGCTGAGACTGAAGAGCATGGCGGGGCTGACGCTGACGAGGGACCTGCGGCCGCTGGCGCAGCTGACGGCGCTGCAGCATCTCTCTCACTTCTATCAAGGTGATCTCTCTCTCCAGTGA
Protein Sequence: MSEEMAIGDNATSEETKLNGDEASAASAVDTDAAAPEPQAEPEAPPVEDAPALAEEVPEVKEEIAEDVNMAEPEQPSDKLVAGDGIDEGDEKRGVKRRASAAFSDAGKEDFKGFETGESEFESSYSEVYSRIVDRLEAEVSAAVKDLTPVRSVMATPSAPLRASKRPRQDTGEKLALDSLDKELLEAVRDMDSSESKIVKKRPSRAVDVGDKRRVIPRPPRRAARHDRDVLPPPAAAAGARLEAGAGVPRGAGRALATQRRYILLHAQGEEAEVHQGGQCLYSNLPLLRLPLERGWKRELVYRAALDAHSRRNADIYYYTPKGRKLRSTREQPPLLRLPLERGWKRELVYRAALDAHSRRNADIYYYTPKGRKLRSTREVSACTATSPPAAAAGARLEAGAGVPRGAGRALATQRRYILLHAQGEEAEVHQGGQCLYSNLPLLRLPLERGWKRELVYRAALDAHSRRNADIYYYTPKGRKLRSTREQPPLLRLPLERGWKRELVYRAALDAHSRRNADIYYYTPKGRKLRSTREVSACTATSPPAAAAGARLEAGAGVPRGAGRALATQRRYILLHAQGEEAEVHQGGQCLYSNLPLLRLPLERGWKRELVYRAALDAHSRRNADIYYYTPKGRKLRSTREVSACTATSPPAAAAGARLEAGAGVPRGAGRALATQRRYILLHAQGEEAEVHQGGQCLYSNLPLLRLPLERGWKRELVYRAALDAHSRRNADIYYYTPKGRKLRSTREVSACTATSPPAAAAGARLEAGAGVPRGAGRALATQRRYILLHAQGEEAEVHQGGQCLYSNLPLLRLPLERGWKRELVYRAALDAHSRRNADIYYYTPKGRKLRSTREVSEHLSGTGLTLENFSFFKEPLGLDDPEKEIIRDAKMIRRVESPVVAQPPTAEGKRTPKPKPPKGASPEPKPPATVKSPPAKIRGKRSPKPPKGASPEPKPPATVKSPPAKIRGKRSPKPKPPKGASPEPKPPATVKSPPAKIRVKSVGSRLSTSSPATPAANTNTKQQKKPADNNNSAAWKKPRPLVAPPVAPPVAPPVAPPVVTPVAPPRPATPPQPPPPLQSRPPPSPDVTSPRQLVQPCSMTCGRGLPTVACAACLCLYHPACIGYNHTATGRVLCKNCRSSPPPLEPPPLTHKSGVSGSSIPAPVPRRLPGPLPVPVPVPVSKIRPDKRVTLRMKVAGGGPDGERVWAVAPQQPPRAVLLRAQLPQSVAVLNGRRFIVVPREIRAPNEDKKRGRVANGAASPPAVMTSPRRRGRPKIDDTDHFTTFYNTAQEKNYNVVVQIFQYLGMRDLAHSARVCKLWRQLAATPALWRHVRMKNSHVSDWGGLCAALKRHGTKRLDLRKMLLPQNDTTFWDQFAHHIGEVDSLERIEMCRCPARAVEAVCACLPSLRALSALAIKDARLDPEPLSRLTLLHELRLKSMAGLTLTRDLRPLAQLTALQHLSHFYQGDLSLQ*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -