Edan002624.1
Basic Information
- Insect
- Ephemera danica
- Gene Symbol
- -
- Assembly
- GCA_000507165.2
- Location
- KZ497834.1:1263696-1280553[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 0.32 1.4e+03 -1.1 0.0 37 47 235 245 234 250 0.88 2 2 6.3e-13 2.8e-09 36.5 0.0 8 71 251 318 244 321 0.83
Sequence Information
- Coding Sequence
- ATGCAAAGTTCTTCGAAATCTCTGACCCGCCGAGGTCCACCGACAGTGCTGAGTGCAAAGGAAGAGAAGGATATCATCCACTGGGCCAATGAACAGATGGTCAGCACACATGTGCGCCACACAGATATTTTGGACCATGTGCAGAAATACCTAAGCAAGGAAGGCCGACAGAACCCCTTCACAAACAATCGGCCTGGCCGGAGTTGGCTAAAATCATTTCTCAAGCGCCACCCCAAGTTTTATGAAACATTGCAGGACTCTCGAAAAGCTTATCGCAGTGGAGACGGTGTCTTCGTACCAGATGACGAGTCAGACTGTGAATCCAATGGAGATGATCAGAGTGACACTGAAGCCTCCTGGGTGATTGATACAAATGACAGCAACAGCAACCTAGACTCTGAGAACGAACTGAAGATGGACTCTTCTAATTCAGATTCCAGAGCTCTTGCTTCCAGCGACACAAACAAAGATTTGGAAATGTTTGTGGACTCTGATGACGATGACGAGTTTTTGGGCTACACCGAAGAAAAGCCAATTTTTGCAACTGATTTGGAGactttaaaatatgaaaacttaGATGCTGTGGATATAACGGGTCTCCCAGATGCCTGGTGGTCCAAGGAAGAGATTGTCACGGCTGCCCCCAACAAGGAGACCACACAGGTCATAGCACCACCTGCTTTTAACACATTTGACAATCCCTCACCAACTGGCACACGGCTGCGCAGTGCAAGCTCCAATCCTGCGTTTAGAAAGCCTTTTGACTATGGTTTCAAACGAGAGATAGTGTATCGAGGAGTTGTGGATGGTGGAGCCAATGCTCGTCGTTTAGCGGACGTTTATTACATTAGCCCAGATGGAAGAAAAATGCGTTCTATTCGGGATGTGTCTGACTATTTGGATGAACGCATTGATGACATTAAACTTTCTCTTAGTAATTTTACTTTCCTCAAAGAACCTATTGGAATGAATGATCCTACAAAAGAAATCGTCAGGGATGCTAAGAGAGGGACATTTTCTCCAAAGTTGAAGAAACCTAGCACTCCTATCAAGCCCCTCGCAAAGCTTGTGAAGCCCAAGGGCCAAGCAATGCCTGTGCAAGCAGTGGTGCCTCGCACTGTGAGTGCTAGCACGGTGGCACCTCGCGCAGTCGCTCCAAGCAAACCAGTGAATGTCGTCAAGCTGCTTCCCGTCACCCAGACTAAGCCTCCAGTGGCTTCTCAATCACCACCTCAAGACAGCAGCATGGCCAATACATCGAGATCCCTGATGCCTCCGTGTTCGATTCACTGTGAGCACGCACCTGGCCTGATTCCCTCCCTTCAGTGCTGCATCTGTGTGTGTCTGTACCATCCAGTGTGTGTAGGACTTCCAGCATCCTCAGAGAATCTCACCAGTTACATCTGCCCTAACTGCAAGCAGGAGAAGGACCAGAACTCCAACATGGCTCAGCAAGACCTGTTGAGTCTCAGAGTGAGCGACCATCCTCGCACCCAAGGTATTCCACAACCTGTGCTGCCACCTCTGTCCATGCTGCACCCCGTGGCCACAATGGAGACCCCCACTATAAGCCAGGGAGACAAGGCCATGTACTCCTTGGGCCACTGGCGTCCACCTCTGATGCCCATGCAAGGAAGCCCAGCGGCTCAGCCGTGGCCAGAGCACATTCCACAGCAGTCGCTGGCAATGATGAATGGCAAGAAATACGTTGTGATTCCTCGCAACAACATCGCTGCAGTGGGCAACTCGCCTGAGGAGGAGATGAGCAAGACCGTTGCATCTCCCATGGCCGTGCCGCCACAAATGCAGCTCACTGCTGCTTCTCAGTTCGGCCCCAATGCAATGTTGCCCAGGGGAGCGTTCTTTGTCAACCAGGCTGGATCGCCGGGCACCATGTTTCTGCTGAAACCAGCAGAAAACCAAGAAGGCTACTCACAGACTCTACCCCAGTTCTTGTTGATGAACCCAGCAAGCACGGTGCAAGCAAATAAGATTGCCACCACCCCATCGAGCGTCTGTGTGGTGCCTAAGCTACCAGAAGAAATGGCTGCTACTGAGGCGAAGGAAGTTCCCCAGCCCTTCACCATGAAGGGTGGCTACAGCTTTACAGAACGCCTAACTGCTCACCACGAAGCTCTGTTGAGTGTCATGCGATACCTAACAGTTCAAGAACTCTTGTGTGTGGCTCGGGTTTGTCGGGCATGGAGACTTGTTGCCAACGATCCTTCTTTGTGGATGTCTGCCCGACTGAAGAATTCTCAAGTGAAAAATTGGGACAGTTGCATGACAGCGTTGCTGAGACATGGCACGACACACTTGGACTTGAGGAAAACTCTGATGCCCAAGAGGGAAGAGGAGGCTCAGGCCGCGTGGCAGCAGTTCTGTACTGCTCTCCGGGAGAGCCCAGCTGGCCAGCTGCTACAGCGCATAGATCTGTGTCGCTGTCCTCCACATGTAGTCGCTACAGTCGCTGAGTGCTGTCCCCAGCTGTGCCTGCTCTCTGCGCCGGCTATCACCACCAAAGCAGACCTCGATTTACAGTCCATCAGCAAACTGAAGAAGCTGCAGGGGTTGCGGCTTAAAACCTTCCATGGAATGACGCTTGAAAACTTCGAAATGTTGAAGAATTCGAGGAATCTCACACAGCTGTCGCTGACTTCCATCCGCATGCTGAGTGCTGTGGACGTTGCGTCTGCCCTTGCAGCCAACTCCCACCTGGAAGTATTGGAGCTTGGAGACTGTCCTGGCCTGCTGACACACCCCTCGCTGGTGGCGAATGCCCTGAGGGAGCTCCGCAAGCTGAGGAGACTGCGGCTTGAGAAGTTGGTCACTGATCCCACCTCGCAACAGGGCGCAGTGAACACGCTTCTGCAAGCTCTGCTCAACACCACGTCTCTCGTACACTTGGAGTTGGTGAACATCGAGGCAGGGCCAGGCTGTGACGAAGCACTGGGAGCGATAGTCTCGCTGCAACAACTGCTTTTGGTCCCAAGTTACCTCACCCATGGAGGAATCACATGCCAACTGCTGTTGAGAGGAGTTCTGAAGCTGGGCCAGTTGCAAGATCTGACTTGGGTGGTGACCAACGAGGTGATTGGCTGCACCAAGAAACTGATCAAAACCCATCAGAGCTACGGGCAGTCGGACGAGTCTCAAGAATGCATTCCCGTGTTGCCCCCCGTGCCTGGCGAGGAGGACACCGATGAGGAAGTGTCTCCCCACAGTTCCAAGCAGAAAACCAGTTTCAAGACAGACAAACTCGTCATGTTGCCCCTGTCTAAGCTGAAAACAATCTTGCACACTGGTTTGCCCAAAACCAAAATAGCATTCAACAGGATCACCTTCCAAGGCACTTGGAGACAAACCCTCTCAGATTGGGATCTTGTAGCATCTTAG
- Protein Sequence
- MQSSSKSLTRRGPPTVLSAKEEKDIIHWANEQMVSTHVRHTDILDHVQKYLSKEGRQNPFTNNRPGRSWLKSFLKRHPKFYETLQDSRKAYRSGDGVFVPDDESDCESNGDDQSDTEASWVIDTNDSNSNLDSENELKMDSSNSDSRALASSDTNKDLEMFVDSDDDDEFLGYTEEKPIFATDLETLKYENLDAVDITGLPDAWWSKEEIVTAAPNKETTQVIAPPAFNTFDNPSPTGTRLRSASSNPAFRKPFDYGFKREIVYRGVVDGGANARRLADVYYISPDGRKMRSIRDVSDYLDERIDDIKLSLSNFTFLKEPIGMNDPTKEIVRDAKRGTFSPKLKKPSTPIKPLAKLVKPKGQAMPVQAVVPRTVSASTVAPRAVAPSKPVNVVKLLPVTQTKPPVASQSPPQDSSMANTSRSLMPPCSIHCEHAPGLIPSLQCCICVCLYHPVCVGLPASSENLTSYICPNCKQEKDQNSNMAQQDLLSLRVSDHPRTQGIPQPVLPPLSMLHPVATMETPTISQGDKAMYSLGHWRPPLMPMQGSPAAQPWPEHIPQQSLAMMNGKKYVVIPRNNIAAVGNSPEEEMSKTVASPMAVPPQMQLTAASQFGPNAMLPRGAFFVNQAGSPGTMFLLKPAENQEGYSQTLPQFLLMNPASTVQANKIATTPSSVCVVPKLPEEMAATEAKEVPQPFTMKGGYSFTERLTAHHEALLSVMRYLTVQELLCVARVCRAWRLVANDPSLWMSARLKNSQVKNWDSCMTALLRHGTTHLDLRKTLMPKREEEAQAAWQQFCTALRESPAGQLLQRIDLCRCPPHVVATVAECCPQLCLLSAPAITTKADLDLQSISKLKKLQGLRLKTFHGMTLENFEMLKNSRNLTQLSLTSIRMLSAVDVASALAANSHLEVLELGDCPGLLTHPSLVANALRELRKLRRLRLEKLVTDPTSQQGAVNTLLQALLNTTSLVHLELVNIEAGPGCDEALGAIVSLQQLLLVPSYLTHGGITCQLLLRGVLKLGQLQDLTWVVTNEVIGCTKKLIKTHQSYGQSDESQECIPVLPPVPGEEDTDEEVSPHSSKQKTSFKTDKLVMLPLSKLKTILHTGLPKTKIAFNRITFQGTWRQTLSDWDLVAS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -