Basic Information

Insect: Ennomos erosarius
Gene Symbol: Hr39
Assembly: GCA_963580505.1
Location: OY756978.1:14061336-14084534[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.31 3.3e+03 -2.0 0.6 114 132 80 104 19 213 0.48

2 5 3 3.3e+04 -6.2 7.1 115 160 269 314 165 330 0.57

3 5 1.5e-07 0.0016 18.8 0.1 1 19 443 461 443 468 0.92

4 5 0.026 2.8e+02 1.5 0.0 80 118 492 528 465 559 0.68

5 5 6.3e-65 6.8e-61 207.7 0.0 201 408 545 762 492 762 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.31	3.3e+03	-2.0	0.6	114	132	80	104	19	213	0.48
2	5	3	3.3e+04	-6.2	7.1	115	160	269	314	165	330	0.57
3	5	1.5e-07	0.0016	18.8	0.1	1	19	443	461	443	468	0.92
4	5	0.026	2.8e+02	1.5	0.0	80	118	492	528	465	559	0.68
5	5	6.3e-65	6.8e-61	207.7	0.0	201	408	545	762	492	762	0.84

Sequence Information

Coding Sequence: ATGAATGCTGCTATGTCCAGCGAAGGAGATGCGGTGAAGGTGGAAGGCGGACACGTCTCAGTGACCACCATCAGCATGTCAGGGTGTCCGGAGACCAGTAATGGTCAGTTCTCGTACAGCTCGAGCGGAGTCCGCATCAGCGTGTCTTCAGAGCCACATGATGAGGACTCGACTGACGCAGAGATTTCCAAGATCGATTTCACGCAGCATCAGTACGAAGTCAACATGCGGAATAATAAGAAACGCTCATACAGCGGCGCCCAGTACGAGACGCAGTCGAACGACCGCGAGCGACCGATGTCGTGGGAAGGGGAGCTGTCCGACTCTGAAATGGTTATCGACACCAGCGTTAATAATGATGAAAACAGCAACTCCCTAGACCTACAGTCGTCCCGAGACTCCATCGACACCCTTCGCAATGTGACTATAAAGACAGAACCGCTCAAAAACGAAGTTTTCCAGAGCTTGGATGACCAGAGGGTACTGGATCTGAAGTATACGGCCCCTTTGCAGTCCCATCAAAGAAGTCTTAGTATGAACAGGATACCAGTACTTACAGACACCGCATCACTCTCTCTCCTCCGAAGACCATCGTCACCGACAAGCAGCGCCAAATCCTTGGCTCTCTCCGACCAGGGATCAGCTTCGATCATGGCGCAGACATCCATCGGGGAGGTCCAGAACTTGACCATTAAGAAGGAGACTTTATCAGAGTTAAAATGCGAGCCGTCAGTGGGCATGGAAAAGCTGCTGGGTGCACTCCACGGTTCACCATTACTCGGCCGGCTGCCGCGCGTCCAGTCTAGCGCCAGCACTGACTCGGCTGTGCATTCCATGTACACACACAGTGTATACAGCAGTCCGTCGGCCAGTCCACGCGCCTCCCGCCACTTCACGCCGTCTCTTTCACGCAATAACAGCGACGCTTCACACAGTTCGTGCTACTCTTACAGCTCAGAATTCTCGCCCACACATTCTCCAGTTCAGTCCCGTCACGGCCCCGTGCCGTACCGCGAGGCGGGCGGCGCGCTGACGTCCCCCGGACACGAGGAGGACGCGGAGGACGACCGCCTCCATCACCACCAGGGGATCAGCAGGCAGCAGCTTATCAACAgTCCATGTCCAATTTGCGGCGACAAGATCAGCGGGTTTCACTACGGCATATTCTCCTGCGAGTCCTGCAAGGGTTTCTTCAAGCGAACCGTCCAAAATAGGAAGAACTACATGTGCTTGAGAGGCGGGAACTGTCCCGTTACTGTGGCGACCAGGAAAAAGTGTCCCGCTTGCCGGTTCGACAAGTGTCTCGGATGTGGGATGAAGTTAGAagcaATACGAGAAGACAGAACAAGAGGTGGCAGATCAACGTATCAATGTTCGTACCCACTCTCTGGCGCATCGTCGACAGGCTCGCTACTGTCCGCACACGTACCTTCCACGTTACGGCACGCCTCCAGTCTCACCTGTGTAAACGGTCCAGGGTCGTACAACAGCAGAGGGGAGTCCAGTAATAGTCGACTCACGCCTGACATACCGCCATTAttgcaaGAAATAATGGACGTGGAACACCTATGGCAATACAACGAGTCCGAACTAAACCGTATCGGCAAGTCGACTGGAGGAAGCCCCTCTGCCAACCCCCTTCTTGCCGCCAGTGGAATCACGGCGCAGAACTCCAGTCCGGACTTCTTAGCCGACCTTTGCAATATCGCTGACCATCGACTGTACAAAATCGTCAAATGGTGCAAAAGTCTGCCACTCTTTAAGAATATCTCTATAGACGACCAGATCTGCCTGCTGATTAACAGCTGGTGCGAGCTACTTGTACTGTCTTGTTGCTACCGCGGCGTCAGCACTCCGGGCGAGGTGCGAGTGGGCGGCGGCAGGGGAATCACGTTGCAACAGAGCGCCAAGTTAGGCTTGACACCGTGTATAGAGCGAATGCTGAGCTTCACCGATCACCTGCGGCGGCTGAGAGTGGACCGATACGAGTACGTGGCATTGAAGGTCATCGTACTCCTCACGTCAGATGCGCCTGAGTTGCGTGAAGCTGAAAAAGTGAGAGCGTCTCAAGAAAAAGCGCTGGCAGCGCTTCAAGCGTACATTGCGACGCACTCGCCGCAAACTCCCGCCAAGTTTGGAGAACTATTGCTGCGGATCCCCGAATTACAGCGGACTTGTCAGTTCTTTATGCAAGTCGGCAAAGAAATGCTAAACCCtgcaaacaaaaacaaagatgGCGATGGACCCAGCTTTAACCTTCTAATGGAACTGTTAAGAGGAGACCATTGA
Protein Sequence: MNAAMSSEGDAVKVEGGHVSVTTISMSGCPETSNGQFSYSSSGVRISVSSEPHDEDSTDAEISKIDFTQHQYEVNMRNNKKRSYSGAQYETQSNDRERPMSWEGELSDSEMVIDTSVNNDENSNSLDLQSSRDSIDTLRNVTIKTEPLKNEVFQSLDDQRVLDLKYTAPLQSHQRSLSMNRIPVLTDTASLSLLRRPSSPTSSAKSLALSDQGSASIMAQTSIGEVQNLTIKKETLSELKCEPSVGMEKLLGALHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRASRHFTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQSRHGPVPYREAGGALTSPGHEEDAEDDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYPLSGASSTGSLLSAHVPSTLRHASSLTCVNGPGSYNSRGESSNSRLTPDIPPLLQEIMDVEHLWQYNESELNRIGKSTGGSPSANPLLAASGITAQNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLQQSAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPELREAEKVRASQEKALAALQAYIATHSPQTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKNKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00042698;
90% Identity: iTF_00806824;
80% Identity: iTF_00649223;