Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.32 9.9e+02 0.9 0.1 23 51 178 206 170 208 0.78

2 6 0.12 3.6e+02 2.3 0.3 21 45 204 228 196 230 0.84

3 6 0.00088 2.7 9.1 0.2 13 46 223 257 213 263 0.79

4 6 0.002 6 8.0 0.1 21 45 260 284 256 288 0.89

5 6 9.3e-05 0.29 12.2 0.1 14 45 280 312 279 315 0.89

6 6 0.00013 0.41 11.7 0.1 21 45 316 340 312 345 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.32	9.9e+02	0.9	0.1	23	51	178	206	170	208	0.78
2	6	0.12	3.6e+02	2.3	0.3	21	45	204	228	196	230	0.84
3	6	0.00088	2.7	9.1	0.2	13	46	223	257	213	263	0.79
4	6	0.002	6	8.0	0.1	21	45	260	284	256	288	0.89
5	6	9.3e-05	0.29	12.2	0.1	14	45	280	312	279	315	0.89
6	6	0.00013	0.41	11.7	0.1	21	45	316	340	312	345	0.89

Coding Sequence: ATGACAGTTTCAGATTCCCCTCTCCAAGACCAAGAAACAATAGAATCGGACCAGGATGAGACAAAACCCAATGTCTCCGACTATGAAGATGATCTACCACTCACCACAGTGCGAATTAAGAAAAAAATTAAAGGGAGGCCACATTTGAAAGTTAAGATGAAGGATTTGGTCATCAAACCAGTGAGAACAGGTGAAGTAGAGACGGGGGAGGGAGATGTTACTTATTTCGTCGGTGAACCTCCTATTGAGAAGACTAAATTAAAACACACGGATACAAAAGAAAAAAGAAATTTACAAATCAACGCAAATATTCAACCAAGATGTCAGAAAACAGAAATTAATAATGTTAATATTGAAAGGCCAAAATCAAAAAATATTAACAAAACTACGTGTAACCAAACCGACATTGAATATATTTGCGACGATTGCGGCTCGAAATTCGATAATAAATGTTTACTTACTAAACATATAGAACATCATAATTTAATGAAATATAAACATCTAAGTATACACTCCGAGGAAAAGCCTTATGAGCCTTATAAATGTGAGATATGTAATAAGAGATTTACGCGAAAGGGTTATTTAAATAAACATCTAAGAATACACTCTGGGGAAAAACCTTATAAATGTGAGATATGTAATAAGAGGTTTAATCATAATACTTCTTTAAAACCCCATCTAAGAATACACTCTGGGGAAAAGCCATATAATTGTGAAATATGTAATATGAGCTTTAATCGAAGTACTACTTTAAAACTGCATCTAAGAACACACTCTGGGGAGAAGCCTTATAAATGTGATATATGTAATAAGAGCTTTAGTCAAAGTTGTTCTTTAAAACCCCATCTAAGAACACACTCTGGGGAGAAGCCTTATAAATGTGAGATATGTAATAAGAGCTTTAATCGAAGTAGTAATTTAAAAACCCATCTAAGAACACACTCTGGGGAAAAGCCATATAAATGTGAGATATGTGATACGAGCTTCAATCAAAGTGTTCAATTAAAAAGACATATAAGAACACACTCGGTAGTATTCGGAAATCCCGTTTCCATGGGAATTTCACGGTAA
Protein Sequence: MTVSDSPLQDQETIESDQDETKPNVSDYEDDLPLTTVRIKKKIKGRPHLKVKMKDLVIKPVRTGEVETGEGDVTYFVGEPPIEKTKLKHTDTKEKRNLQINANIQPRCQKTEINNVNIERPKSKNINKTTCNQTDIEYICDDCGSKFDNKCLLTKHIEHHNLMKYKHLSIHSEEKPYEPYKCEICNKRFTRKGYLNKHLRIHSGEKPYKCEICNKRFNHNTSLKPHLRIHSGEKPYNCEICNMSFNRSTTLKLHLRTHSGEKPYKCDICNKSFSQSCSLKPHLRTHSGEKPYKCEICNKSFNRSSNLKTHLRTHSGEKPYKCEICDTSFNQSVQLKRHIRTHSVVFGNPVSMGISR

Sequence clustering based on sequence similarity using MMseqs2