Efla008803.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Endotricha flammealis
Gene Symbol
ttk
Assembly
GCA_905163395.1
Location
LR990855.1:11294960-11297412[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.1e-31 4.9e-29 101.6 0.4 1 106 21 122 21 124 0.94

Sequence Information

Coding Sequence
ATGGCGACGCAAAGGTTTTGTTTGAGGTGGAACAATCACCAGTCGAATATGTTGTCAGTATTCGACCAGCTGCTGCACGCTGAAACGTTCACAGATGTTACGTTGGCAGTAGACGGCCAACTGCTGAAAGCCCACAAAATGGTATTATCGGCCTGCAGCCCATACTTCCAGGCTCTATTCGTCAACCACCAAGAAAAACATCCTATTGTTATACTCAAGGATGTTCCATATTCAGATATGAAAAGTTTATTAGACTTTATGTATAGAGGCGAAGTGAGCGTGGATCAAGAAAGGTTGACAGCCTTCTTAAAAGTAGCCGAAAGTTTGAGAATAAAGGGCTTGACTGAGGTGAACGAGGAGAAGTGCGACATACCTGCTCTCACTAACTCCCTAATCCAGCAGCAGGGTGGGTCCACACATACACCGCCGCCTCAGTTACACAGAATACATCCTTACATGCACCAGAAACGGCCAGCGTCCGGAATGCCTAGTGGAGGCGCACCACCAAACTTATTAATGCCTTTGTTGGGCAACGCTCTAATGCAGCCAAAAAGAAAACGAGGTCGGCCTAGAAAATTGAGTGGAAGTTCAAGCGACGCTTTGAACACGGCGGCCAGTCCCCCTGGAGAGTTTATTCCAGAATCGGCTTCTCATGCTCAGTCCAACAGAGCAGGTGATCAATTAATTCGAGGCTCACCAGAAATGTTGGAAGTTAAAATGTCTATGGACGGCTTCAGCGCTGAAGACGGAGCCACTTCTGGCGGCGAGGAAGCGGGCGAGGGTCTCCTAATTGATGAAGGAGACGACGCCCACATGACTGAAGCCCCCACCGGAAAAGACTCCGAATCTGCAGATCCAGATAAAGCGGCCAAAGAGGAATCACAGCCAAACTATCCGACAAACGGCCCGATTCTGTCCATTGAAAACGGATCTATAAAAGCGGAGCCCGCCACTGATACTAACGACGGTTACAACGAGCCAATCGAATATAAATACAACCCTGATAGAAGTCGCGAAAACTCCAATTCTCAGGACGGTCTCATAAAAGACTCAGACGATAAAAACAGACTAGGTCGTAACTTGAAGCCAAAGAATAGCAAAAAATTACTACCCCAAATGTCAAAAATCAGAGCTCGCAACTTATTCAATCAGCTGTCCGGACTGTCCAACTTGAATCCCGCGTTGAACACTTTCGACAAATATCCGCCCGAGACTGTGCTCATGCCGGCTCTTGCCACTCAATTATTTGCCGCTGAATTAGAACAGAATAATCTGAATTTGGCTAACAACGAAGTTACGGATTTAGCGCAAACTAATTGGGAACACCGAATATTTCCATCGCCTATTAGGAAAAATAATTTAGGAAATGTCGGTAACTACCACGAGGAGACTAACGAGTCTGTCAGGGACTACTGTATTAAGGAAGGGGAGAACGTCTTCAGATGTAAGATTTGCGCGCGAGTTTACACTCACATTAGCAATTTCTGTCGACACTACGTCACTTCACACAAGAAGGACGTCAAGGTGTTTCCGTGTCCGATATGTTTCAAAGAGTTCACCCGAAAAGATAATATGATTGCACATCTTAAAATCATTCACAAGAATCAACCAAACTCCAACGAACAATTGGCAAAACAGGAGTCTTAA
Protein Sequence
MATQRFCLRWNNHQSNMLSVFDQLLHAETFTDVTLAVDGQLLKAHKMVLSACSPYFQALFVNHQEKHPIVILKDVPYSDMKSLLDFMYRGEVSVDQERLTAFLKVAESLRIKGLTEVNEEKCDIPALTNSLIQQQGGSTHTPPPQLHRIHPYMHQKRPASGMPSGGAPPNLLMPLLGNALMQPKRKRGRPRKLSGSSSDALNTAASPPGEFIPESASHAQSNRAGDQLIRGSPEMLEVKMSMDGFSAEDGATSGGEEAGEGLLIDEGDDAHMTEAPTGKDSESADPDKAAKEESQPNYPTNGPILSIENGSIKAEPATDTNDGYNEPIEYKYNPDRSRENSNSQDGLIKDSDDKNRLGRNLKPKNSKKLLPQMSKIRARNLFNQLSGLSNLNPALNTFDKYPPETVLMPALATQLFAAELEQNNLNLANNEVTDLAQTNWEHRIFPSPIRKNNLGNVGNYHEETNESVRDYCIKEGENVFRCKICARVYTHISNFCRHYVTSHKKDVKVFPCPICFKEFTRKDNMIAHLKIIHKNQPNSNEQLAKQES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01208385;
90% Identity
iTF_00736714; iTF_00737104; iTF_00648731; iTF_01426337; iTF_01426022; iTF_01173394; iTF_01173815; iTF_00622449; iTF_00622094; iTF_01073714; iTF_01074084; iTF_00683809; iTF_00682950; iTF_01335110; iTF_00683465; iTF_00681739; iTF_01335563; iTF_00682544; iTF_00682002; iTF_00027396; iTF_00027879; iTF_00028342; iTF_00026971; iTF_00406852; iTF_00407206; iTF_00407686; iTF_00408032; iTF_01265430; iTF_01264805; iTF_00831351; iTF_00831759; iTF_01117467; iTF_01117896; iTF_00761796; iTF_01417354; iTF_01251948; iTF_01083470; iTF_00007632; iTF_00762194; iTF_01416954; iTF_01252379; iTF_01083868; iTF_00007231; iTF_00365413; iTF_00075105; iTF_01282465; iTF_01281860; iTF_01281445; iTF_01282952; iTF_00961482; iTF_01125579; iTF_00752590; iTF_00365039; iTF_01071730; iTF_01279826; iTF_00408563; iTF_01504371; iTF_00752180; iTF_01280948; iTF_01503476; iTF_01280501; iTF_00961049; iTF_01072090; iTF_01279387; iTF_00074652; iTF_01503997; iTF_00408928; iTF_01124704; iTF_00076100; iTF_00075654; iTF_00076678; iTF_00077139; iTF_00285030; iTF_00034897; iTF_00284661; iTF_00036246; iTF_00035262; iTF_00382782; iTF_00035839; iTF_00383232; iTF_00187274; iTF_00187687; iTF_00859099; iTF_00860036; iTF_01010502; iTF_01359367; iTF_01401831; iTF_00994856; iTF_01010922; iTF_00291179; iTF_00064113; iTF_00994449; iTF_01090902; iTF_00859607; iTF_01401401; iTF_00674394; iTF_00858684; iTF_00290813; iTF_00063710; iTF_01091326; iTF_01358974; iTF_00674784; iTF_00448253; iTF_00448629; iTF_00341862; iTF_00341443; iTF_00428257; iTF_01317410; iTF_00429539; iTF_01316483; iTF_01317859; iTF_01430406; iTF_00788169; iTF_00428650; iTF_00787788; iTF_01316914; iTF_00112598; iTF_00112982; iTF_00819288; iTF_00429146; iTF_00819706; iTF_01430043; iTF_00432774; iTF_00432354; iTF_00468262; iTF_00468612; iTF_00006376; iTF_01081706; iTF_00006704; iTF_01082046; iTF_00844488; iTF_01501261; iTF_01501716; iTF_00844949; iTF_01336986; iTF_01337410; iTF_00275899; iTF_00275430; iTF_00178332; iTF_00178805; iTF_01332173; iTF_01334004; iTF_01334391; iTF_01331800; iTF_00279221; iTF_00279594; iTF_00833678; iTF_00833189; iTF_01020816; iTF_01020425; iTF_00237105; iTF_00235954; iTF_00236732; iTF_00236286; iTF_00948401; iTF_00948005; iTF_00323602; iTF_00323942; iTF_00806834; iTF_00807276; iTF_01403986; iTF_01403562; iTF_00355316; iTF_00355762; iTF_00208981; iTF_00208015; iTF_00208444; iTF_00209436; iTF_01416405; iTF_01416001; iTF_00078010; iTF_00077613; iTF_00277018; iTF_00276563; iTF_00357050; iTF_00356407; iTF_00150747; iTF_00151175; iTF_00943355; iTF_00942938; iTF_00146940; iTF_00146541; iTF_00720894; iTF_00720461; iTF_01565246; iTF_01564791; iTF_00652320; iTF_00651865;
80% Identity
iTF_00648731;