Eonu020103.1
Basic Information
- Insect
- Empoasca onukii
- Gene Symbol
- MBD-R2
- Assembly
- GCA_018831715.1
- Location
- CM032061.1:47733421-47771019[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 3.4e-10 3.8e-06 27.7 0.0 9 72 351 409 345 414 0.86 2 2 1.8 2e+04 -3.5 0.0 8 27 435 457 432 462 0.55
Sequence Information
- Coding Sequence
- ATGGCACGCCAGGCGACAAGTGGTTTTCCCTCTTCAGGCGACGTCATAACGGTCGGTTCGCGCAACTCGATCCCAAGAGTTTGCGAAATGTGGAGCAAGTGCTACGCCAAACCTGCCACCAATGTTAAGATAGGCCCGATGTCGTTAGATTTTCCCAGGCCAAAGAGAAATAAGAAGAAAACAGGAGGAGGGCTACTGATCACACCAAAACCTCTCGATTCTCCCCAGCTGTCGACACCTGTAATGCCACAACCAAACTTTCCTGATGGTCCGCCTTCAAGCGATGGAGAAGATGAGGGAACAGACGACTTCAACAGTCAAGATAGCCAACCCGACAACAATGACTTTCTACCAGGATGCCGTTTAGAAGTCATGGATTTCAATGATGAGAAATGGTATTCTGTGAAGGTGGTCGAAGTAGACTACGACGAAGGCGAGGTCTTGGTTCACTTTGAGAAGTGGTCAGATAGATACGACGAGTGGGTCAGGATGGACAGCAATTGTATCCGTCGGCCTCAGCTGCCCCAGAATAGTTCTAGAAAGGTGTTTGAGAAAAATGAAAAGGTGATGGCAGTGTGGGCGTATAGTTTGAAATGCCCAGCTACGGTTAGGGAGGTTTTGCCCAATGaTCGATACGAGGTCATTTTTTGTGATGGCTACGCTAAGATCTTGCGAGGATGTAAACTTTTCAAAGCAACGGAAGAAGACCTTAAAAACAACCAGCCCCCTCCACCCAAGAAGCCAGCACCTCCGATGGGAGCCGACCCCCTGGACCCTGACCTGGGCCCTAAAGAAGAGCGAAGGCTGAAGAAACGGAAAATAGACGTCCTGGAGTCTTATCTTCCTCACAAAAAAATCAAacAAGAACCTTGTTCCTCAGTGGAGTCGTCACCACAGACGTTCTCGTCCCCGCGCAGCTCCAAGGACAGCTTGGTGCACAAGATGATGAAAGAAGAGAGCCAGAGTCAGAGCCAAGAGGACGATGATGACGACAATCGACTGTTTGTGGATGAGGGAGGGTACTACCGAGAGTCGATCGTGATTCCCGACGGCAGACTGCCGAGTGGGTGGAGCAAGCACACGATGTTGAGGAGGAACGGCAGCAAGTGGGATGTGTTCCTCGTCAACTCGGAAGGCAGGAAGTTCCGGTCACGAGGTGAGCTGCGCAGCTACTTTGCTGACTTGAAGGAGGACTTCCCCTCTGAATCGTTTGACTTCATGGTGGGCCGGAAGTTTGACCACATCAAGACCCGGGAGGAGAACAAGGGAGTGCTGAAGAAGATAATCCCTGGCTCTCCTCTCTCCTTGCCCGCCAAGCCTGCATACAAGACATCCATCTACAAAAGGAAAAGGCGAAAGTCTGGGTCCACCAGCTGGACATCGGACTACAAGAAATCAAAGTCAACAACACCGAAAATCAAGGAAGAGGAAGATGTGAAGTCCCCCTCGACTCCAGTCGTCCCTGCTCCCTCCATGGACCTTTCAGGTAACCACACTGTCCTTGTCGCTCTTGAAGCAGCTTTTGTCAAAAAGTTCAAAACTCCAGATGGCGGCTACAAGTGTTGTAATAAAAACTTTCGTAAAGAAAACCTATTTCAAATGCACATGAAGCACTACCACCCCGAGTACAGCAAGATGTTTGCGTGTACGCCGAATGTGGCAGACTTGGCGTATGCACGTACCACAAGGGAGCCGCTGGAGGACTCTCGTGCCGAGGCCATGACGCCGAAACACTCCTTCTCCGAGCTTGTCTCCAAGTATCAGCAAGAGCGTAAGGCACTCTCGGAGTCTCCACTAGCGGCAGCTTCACCCAGTGTGAAAAAAGAAGTAGATCAAAGTTCTCATTCAGTCGTTAAGGACAAGGCAGAAACCCAGACATTTCCTGAAAAACACACAGAAGAAGTGCCTGCCGGGGACTCAAGCCCAAAGAAGAAATCCGAAACTGACAAGGAAGAAGAAACGTCTGGTCCAAAAAACGAGGAAGCTAGCACATCCTCCAAGGATGTGAAACCGgaaATTTCATCTGAAGAAAACTTAAGTGCAAGTGAAAAAGAAAGTAGTAAATCTTCACGAGAACCTTCAGCTGCACTAGTAAAAGAGCCCATGGCTTCGTCAGTTACTAAGTACGTCCCACCGGACAAGAAACCACCGACGTCCCTCGCCAAGATGACGATATCGATGCTATCTGAGGACAAGGATAAACCGAATGAGACGAAAGAAACCAAACCTGGCAAAGAGACAGAAAAAGAAGCCAAACCTAAAGACACGGCAAAGGAAACAAAacctaaagaaataaaagaagcTAAAACAAAAGATACGAAAGAAGccaaatttaaagaaacaaaagagTTCAGAGGAAAAGAGTCTAAAGAACCAAAGCTGAAAGAGGCGAAAGATCCAAAGTTGAAAGAAAGCACGATTAAGACCATAAAAACTCTGATGCCAATGCGACCACCCAACACTACTGAAAGCAAAGAGACACCTGATGTTGCCAAACCGAAAGATGTCAAGACTAAAGAAGAGATTGAAGAGGAAGTACCCATCAAGTCGAAGCCTGGCAGAAAACGAACAGCTTCTGAATCCTTGCAGAAAAAGTCAAAACTCATGAAATTATCAACAGGCTCTCTGGAAGAACATTTATCGGTTGCTGAAGAGACAGAAGTCCCAGTTTCCCCCACCAACGGGAACAAGAGCTATCGATTCTCTCGCAATCGCTCGCAGGGTGTTCCCAAAGTTTCCTTACAAAAACTTAATATCAGCACAGATTCCAACGGCTCTCTGGAAGAACATTTATCGGTTGCTGAAGAGACAGAAGTCCCAGTTTCCCCCACCAACGGGAACAAGAGCTATCGATTCTCTCGCAATCGCTCGCAGGGTGTTCCCAAAGTTTCCTTACAAAAACTTAATATCAGCACAGATTCCAACGATGCCTTCAAGCGTAGGGCTTCTAGTTGGTTGATTGATCTTGGTGTGTCAGAGGTAGAAAGGCTTATCACAGCTGAGTACAGACAGGGACTGACGCATGAGAGTGCTGCACAAGCCGAACCGGCTGCTGCGGAGTTAGCTGCGTCGCAGGAGAGCAACCTGGAGAACCTGCGCAAGGAGGAGATCATCAACTGCACCTGCGGCTACATGGAAGAGGACGGTCTCATGATTCAGTGTGACCTGTGCCTGTGCTGGCAGCACGGCATGTGTAACAACATTGACAAAGAGGCGGATGTACCAGAGAAGTACGTGTGCGCCATCTGTCAGAACCCGCCACGTCTGCACATCCATGCGCTACATGAACAACCAGGACTGGATCAAGGAAGGCAAACTGCCAAGTTTGCCATTCCGGCCCAAGTCTGCGGAGGCGATGAATCAGCGCCAGTCGATGTTGCAGGCTTCTCACAAACTCACCGGCTCTCTGCTTCAACTGCAGTCTGTCATACACAGTCTGCGTGTCAAGACTCACATTGCCACCCTGAAGCAGCAATAGACGCAATGGAGTGTCGACTTCACTTGCTGGAACACGTAGAGGACTATCAACAACAGGTCGAGGATAGGCTGACGTCGGTACAGGCTCAGATCGCAGCTCTAGAGTCAGAGGACCCGGATCTAGCCAATGATGACGAGGATTCAGACACTTACCCCGTTACAAAGCAGACACTACAGATGCTGATTCACGACCTGCAGACTGTGCAGCAGGCGGCTACGGTGACAGTCAACCAGGCTGCAGTCGCGTAG
- Protein Sequence
- MARQATSGFPSSGDVITVGSRNSIPRVCEMWSKCYAKPATNVKIGPMSLDFPRPKRNKKKTGGGLLITPKPLDSPQLSTPVMPQPNFPDGPPSSDGEDEGTDDFNSQDSQPDNNDFLPGCRLEVMDFNDEKWYSVKVVEVDYDEGEVLVHFEKWSDRYDEWVRMDSNCIRRPQLPQNSSRKVFEKNEKVMAVWAYSLKCPATVREVLPNDRYEVIFCDGYAKILRGCKLFKATEEDLKNNQPPPPKKPAPPMGADPLDPDLGPKEERRLKKRKIDVLESYLPHKKIKQEPCSSVESSPQTFSSPRSSKDSLVHKMMKEESQSQSQEDDDDDNRLFVDEGGYYRESIVIPDGRLPSGWSKHTMLRRNGSKWDVFLVNSEGRKFRSRGELRSYFADLKEDFPSESFDFMVGRKFDHIKTREENKGVLKKIIPGSPLSLPAKPAYKTSIYKRKRRKSGSTSWTSDYKKSKSTTPKIKEEEDVKSPSTPVVPAPSMDLSGNHTVLVALEAAFVKKFKTPDGGYKCCNKNFRKENLFQMHMKHYHPEYSKMFACTPNVADLAYARTTREPLEDSRAEAMTPKHSFSELVSKYQQERKALSESPLAAASPSVKKEVDQSSHSVVKDKAETQTFPEKHTEEVPAGDSSPKKKSETDKEEETSGPKNEEASTSSKDVKPEISSEENLSASEKESSKSSREPSAALVKEPMASSVTKYVPPDKKPPTSLAKMTISMLSEDKDKPNETKETKPGKETEKEAKPKDTAKETKPKEIKEAKTKDTKEAKFKETKEFRGKESKEPKLKEAKDPKLKESTIKTIKTLMPMRPPNTTESKETPDVAKPKDVKTKEEIEEEVPIKSKPGRKRTASESLQKKSKLMKLSTGSLEEHLSVAEETEVPVSPTNGNKSYRFSRNRSQGVPKVSLQKLNISTDSNGSLEEHLSVAEETEVPVSPTNGNKSYRFSRNRSQGVPKVSLQKLNISTDSNDAFKRRASSWLIDLGVSEVERLITAEYRQGLTHESAAQAEPAAAELAASQESNLENLRKEEIINCTCGYMEEDGLMIQCDLCLCWQHGMCNNIDKEADVPEKYVCAICQNPPRLHIHALHEQPGLDQGRQTAKFAIPAQVCGGDESAPVDVAGFSQTHRLSASTAVCHTQSACQDSHCHPEAAIDAMECRLHLLEHVEDYQQQVEDRLTSVQAQIAALESEDPDLANDDEDSDTYPVTKQTLQMLIHDLQTVQQAATVTVNQAAVA*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -