Basic Information

Gene Symbol
rfx7.L
Assembly
GCA_018831715.1
Location
CM032064.1:32233648-32242177[-]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.3e-24 9.5e-20 72.2 0.0 3 76 84 152 82 155 0.94

Sequence Information

Coding Sequence
ATGTCGTCCAGACCCGAGATCGTCTTTGTTTTCACTGAGCCAATGGACTTGGTTCCAGTCTTCGCCTCTTCGGACAGAACGCCAGAATGCATAGCTGTAGTTGACAGTTTGTTGGACAAAATTAAACAGCTTTCAGTTCTTCAAAAAGCTCTGCTCTACTTAAAGCTTCCTACGTCCAGAGAGGACCCAGATCTTTTAGAGCCTCTTCGAAGACCACTTAATCCACTCGGTAATCGCCAGGAGGTGAGTCAGGCCTTATCCTACATCAAAACCCACTTCTCTCCAGATCCAGACATCTCTCTACCAAAGAAAGAAATTTACAATGAATACAGCAGGAAATCAAGGCCACTGTCCACAGCCGACTTTGGTAAAGCTATGAAACAGGTTTACCCGGTGGTGAGGCCTCGTCGACTCGGGGAAAGGGGTAACTCTCGTTACTGTTACTCTGGCTTGAGCAACTGTGGTGATCTCAGTCGGCCTAGCACAGCTTTTTCAAGTCAGGTAAGACTACTGCACTCTATCTAA
Protein Sequence
MSSRPEIVFVFTEPMDLVPVFASSDRTPECIAVVDSLLDKIKQLSVLQKALLYLKLPTSREDPDLLEPLRRPLNPLGNRQEVSQALSYIKTHFSPDPDISLPKKEIYNEYSRKSRPLSTADFGKAMKQVYPVVRPRRLGERGNSRYCYSGLSNCGDLSRPSTAFSSQVRLLHSI*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-