Basic Information

Insect: Empis stercorea
Gene Symbol: ham
Assembly: GCA_949752835.1
Location: OX457089.1:39816836-39846091[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.4 1.4e+02 4.0 0.6 1 22 331 352 331 354 0.89

2 9 0.0033 0.34 12.3 2.8 1 23 361 384 361 384 0.94

3 9 3.9e-08 3.9e-06 27.8 1.5 1 23 390 412 390 413 0.96

4 9 6.3e-07 6.3e-05 24.0 2.7 1 23 419 441 419 441 0.97

5 9 4.6e-05 0.0047 18.1 5.0 1 23 447 469 447 469 0.99

6 9 0.004 0.41 12.0 3.5 2 21 477 496 476 497 0.95

7 9 2.1e-08 2.1e-06 28.6 1.3 1 23 939 961 939 961 0.99

8 9 5.7e-07 5.7e-05 24.1 1.7 1 23 967 990 967 990 0.97

9 9 5e-05 0.0051 18.0 6.8 1 23 996 1018 996 1018 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.4	1.4e+02	4.0	0.6	1	22	331	352	331	354	0.89
2	9	0.0033	0.34	12.3	2.8	1	23	361	384	361	384	0.94
3	9	3.9e-08	3.9e-06	27.8	1.5	1	23	390	412	390	413	0.96
4	9	6.3e-07	6.3e-05	24.0	2.7	1	23	419	441	419	441	0.97
5	9	4.6e-05	0.0047	18.1	5.0	1	23	447	469	447	469	0.99
6	9	0.004	0.41	12.0	3.5	2	21	477	496	476	497	0.95
7	9	2.1e-08	2.1e-06	28.6	1.3	1	23	939	961	939	961	0.99
8	9	5.7e-07	5.7e-05	24.1	1.7	1	23	967	990	967	990	0.97
9	9	5e-05	0.0051	18.0	6.8	1	23	996	1018	996	1018	0.99

Sequence Information

Coding Sequence: ATGCTATTCGATCGGTATGCAATGTCAGGAAGTAGTGGTGACGAATACGAATCAACAATTCCCCATTTTCATCACAAATATACAAATCATTTACCATCACATCGATATAATCCATATCATACTACAGCACCGACGGTTGTTAGTGGAACAAATAATACAGGAACATCAACAGATTTAATAAATCATCCAACTAATTTAAAAGTGATACCATTAAGTCCGGATAGTAGTAGTGGTATTGGTAATAATTATATTGATCCATATAAATTAATGCAATTGGATCGGACACGCGAATTAATGAGTTTTAATGATTTTACGGATAATCGTGATCTGAGAATATCGGATTTAGATATTCGGGAAGATGGTATTTATGCAAAAGTATTATTACATCGTGGTGTCCGTTTAGGACCTTTTTCAGTGAAAAGGTGTAATGAACCAAAGGATAAGAGATATGCATGGGAGGTTGTTTTTGGTTCTAATGTTCATGGATGGCTAGAACCTGGTGTAGAAGTTACAAATTGGTTAAGAAAAATACGTATTGTAGATAAAACAAAAGATGCAAATttacaacattatttaaatGGATATTATGTATGGTATGAAATTTGTAAAGATATTGAAGCTGGTGATGAGTTAATTTGTGGTCCAAAACATCCAATACAATTGAAGGATATTTTTCGAGATGATATTATAAATCAATTGGCAATgaattgtgaaaataaattaagtgaTAGGGAAAGTATTAATGGATCTCAACATAGTGGTACAACCGGTGAAGACGAATTTAATACATCAAATGATTTGAATATTAgcaatagtaaaaattttaataaaaataaaactttaaaaagaaaattcaatcaTCGacatagtaataataataataataacaataataataatcatcatcataatcatcatAACAACAGTAGTAAtagtcataataataataatagttacgATCAAGACACTGATGACGAAGAAGgaattgatttccgttgtgttGTATGCGAAAGACAATGTCAAGATATTGACCATTTAGACGATCATTTAGTTGCTGCCCATCATTATCCAAAGGACGCTTTTCGTTGTGAATTGTGCTCAAAAAGTTATTGCTATCGACCATCATTATTAAGACATCGTGCATTATCGCATGGTGAAGCTAGAAAATATCCTTGCGAAAATTGTCCAAAGGTATTTTGTGATCCATCAAATCTTCAACGACATATACGTGCTCATCACGTTGGCTGCAGAAGTCACGTATGTCCAGAATGTGGTAAAACATTTACAACATCATCTGGTTTAAAACAACATACACATATTCATGCATCTGTAAAACCATTTCAGTGTGAGGTTTGTTTTAAAGCGTAtacacaattttcaaatttatgccGGCACAAACGTATGCATTCCGATTGTCGTACACaaattaaatgtcaaaaatgtGGTCAAAATTGTAATACACAATCTTCATTATCAAAGCATAAACGTTTCTGTGATTCAACACAAGCAATACCATCCCATTCACAAGGCTCGcaccatcaacaacaacaacaacaacagcagtaTCATCATCATCCGAGTGTATTATCTTCACAGCAACAGCAATCGGAAGGAAGTGGCGGAGGTGCAATTGGAGGAATAGGACCACCACCACCATTATCATCAACGGGCAAGCAATCACAATCAGCAGTAAATAACGGATTGTCAACAGGAGGAATACCAACTGCAATGACTACCCCACCAAATCCATTCTTTATGTTTCGCGGACCGCCACAATTTTTTCCACCTGGTTTTGGACCATATGGATTACCTGGTATATTTCCACCTAGTCCAGCACAAGCACCAAGTTTTCCATTTATGTTTCCGAAAACAAATTTAGAAATGGCTATGACTGCAGCTGCTGCTGCTGATAAAGACAGGTGTTATTCAccaaatagaaataatatagGATATGGTAGTTTAAGTAGCAGGCTGAATAGTATTGGTGTAGGTGGAAGATCAGAggatgataataaattaaataatttaagacgGCGGTCACCAGCTAGGCCAATAcctatatcaaatttaattaaaaacgaaTTAAAATATGATGCACATTCtccaaaaatacataatattcaGAGTTCAGATGATGATACCAATTCATCGGCAATAGATTTAAAAGTTTCCTTTGGTAACAGTGTCCAATATATGAAAACAAAAGAGGAACGAATGTCTTTGGAAGATAAGgtTTCAATAAATGTAACAACAACTCCATCACCAGTCAACGAAGAACTGGAAGATTCTGAAGTGACAACAACAACTGGAGTAGAGCAACCATTAGATTTATCGGTGTCACGAAAACGACCAGCTAGTAGAAGTGTTTCATCAGAACCAGACTTACAATTGGAACCGCCAGAACCAAAACTATCTAAATCACCATCACAACATTCTTCATTTCAAGCAAGCCCTTTACATTCTGTTTCACCAGGACCAACTCCATCACCATCTCCACCCGGACCAACAATGGCTTGTCCCCGGCCAATTCATCCTATGCTTCTTGAAGCAGCTAATTATCGACCACAAACTGCAGCTGATATATTAGCGGCATTTCAAAGGCCATTTCCTTTTTTAGGACGAATGGGCAACTCAGGCAGACCAAATGGATATGATCAGTTGTTgcatcatcatcaccatcacCAGCAACAACATCACCATCATCAGCGCAATGGTACAGTTGGGCCATTTCCACCAAAGCCATTTCATGAAGCATTAATGGCTGCTGGTGGTTTAGCAAATAGTCTCACATCAACTGGAAAAATTAAAGATCGTTATACTTGTAAATTTTGTGGTAAAATTTTTCCAAGATCTGCTAATTTAACACGCCATTTACGGACACATACTGGTGAACAAccatataaatgtaaatattgtgAAAGATCATTTAGTATTTCAAGTAATTTACAACGACATGTtagaaatatacataataaagaGCGTCCATTTAAATGTCATTTATGTGATCGTTGTTTTGGTCAACAAACAAATTTAGATCGTCATTTGAAAAAACATGAAGCTGATGCTAATGGTTTAGGTTTAGGTGTTGGTGATTCACCATCATCTAATGAAGCTGATAGGGAAGATGCATGCTTTGATGAGATTCGTTCGTTTATGGGGAAAGTAACATATACCGGTGGTGGTATGTATACACCAACTAGTATTGGTATTGGTGAAAATGAAACAGAAGATGGTAGTGATGTTGATACAGAAATGTGTACAGATAAAGATTCATTAAACAATAATGATGCACCAATTGAAGTgtcaacataa
Protein Sequence: MLFDRYAMSGSSGDEYESTIPHFHHKYTNHLPSHRYNPYHTTAPTVVSGTNNTGTSTDLINHPTNLKVIPLSPDSSSGIGNNYIDPYKLMQLDRTRELMSFNDFTDNRDLRISDLDIREDGIYAKVLLHRGVRLGPFSVKRCNEPKDKRYAWEVVFGSNVHGWLEPGVEVTNWLRKIRIVDKTKDANLQHYLNGYYVWYEICKDIEAGDELICGPKHPIQLKDIFRDDIINQLAMNCENKLSDRESINGSQHSGTTGEDEFNTSNDLNISNSKNFNKNKTLKRKFNHRHSNNNNNNNNNNHHHNHHNNSSNSHNNNNSYDQDTDDEEGIDFRCVVCERQCQDIDHLDDHLVAAHHYPKDAFRCELCSKSYCYRPSLLRHRALSHGEARKYPCENCPKVFCDPSNLQRHIRAHHVGCRSHVCPECGKTFTTSSGLKQHTHIHASVKPFQCEVCFKAYTQFSNLCRHKRMHSDCRTQIKCQKCGQNCNTQSSLSKHKRFCDSTQAIPSHSQGSHHQQQQQQQQYHHHPSVLSSQQQQSEGSGGGAIGGIGPPPPLSSTGKQSQSAVNNGLSTGGIPTAMTTPPNPFFMFRGPPQFFPPGFGPYGLPGIFPPSPAQAPSFPFMFPKTNLEMAMTAAAAADKDRCYSPNRNNIGYGSLSSRLNSIGVGGRSEDDNKLNNLRRRSPARPIPISNLIKNELKYDAHSPKIHNIQSSDDDTNSSAIDLKVSFGNSVQYMKTKEERMSLEDKVSINVTTTPSPVNEELEDSEVTTTTGVEQPLDLSVSRKRPASRSVSSEPDLQLEPPEPKLSKSPSQHSSFQASPLHSVSPGPTPSPSPPGPTMACPRPIHPMLLEAANYRPQTAADILAAFQRPFPFLGRMGNSGRPNGYDQLLHHHHHHQQQHHHHQRNGTVGPFPPKPFHEALMAAGGLANSLTSTGKIKDRYTCKFCGKIFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCHLCDRCFGQQTNLDRHLKKHEADANGLGLGVGDSPSSNEADREDACFDEIRSFMGKVTYTGGGMYTPTSIGIGENETEDGSDVDTEMCTDKDSLNNNDAPIEVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00643504; iTF_01297893;
90% Identity: -
80% Identity: -