Basic Information

Insect: Empis livida
Gene Symbol: ham
Assembly: GCA_963932195.1
Location: OZ010649.1:43319538-43348363[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.59 36 5.3 0.5 1 22 323 344 323 346 0.90

2 9 0.0019 0.12 13.1 2.4 1 23 353 376 353 376 0.94

3 9 0.0004 0.024 15.2 4.9 3 23 387 409 382 410 0.83

4 9 1.9e-06 0.00012 22.5 1.7 1 23 416 438 416 438 0.95

5 9 4.8e-05 0.0029 18.1 5.0 1 23 444 466 444 466 0.99

6 9 0.0019 0.11 13.1 3.5 2 21 474 493 473 494 0.95

7 9 2.2e-08 1.3e-06 28.6 1.3 1 23 926 948 926 948 0.99

8 9 5.9e-07 3.6e-05 24.1 1.7 1 23 954 977 954 977 0.97

9 9 5.2e-05 0.0032 18.0 6.8 1 23 983 1005 983 1005 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.59	36	5.3	0.5	1	22	323	344	323	346	0.90
2	9	0.0019	0.12	13.1	2.4	1	23	353	376	353	376	0.94
3	9	0.0004	0.024	15.2	4.9	3	23	387	409	382	410	0.83
4	9	1.9e-06	0.00012	22.5	1.7	1	23	416	438	416	438	0.95
5	9	4.8e-05	0.0029	18.1	5.0	1	23	444	466	444	466	0.99
6	9	0.0019	0.11	13.1	3.5	2	21	474	493	473	494	0.95
7	9	2.2e-08	1.3e-06	28.6	1.3	1	23	926	948	926	948	0.99
8	9	5.9e-07	3.6e-05	24.1	1.7	1	23	954	977	954	977	0.97
9	9	5.2e-05	0.0032	18.0	6.8	1	23	983	1005	983	1005	0.99

Sequence Information

Coding Sequence: atgcTCTTCGATCGGTATGCAATGTCAGGAAGTAGTGGTGACGAATACGAATCAACAATTCCTCATTTACATCACAAATATACAAATCATTTACCATCCCATCGATATCATCCGTCTGCGCCGACGGTTGGTAGTGGAACTAATATAGGATCATCAGATTTAAATCATCCGACTAATTTAAAAGTGATACCATTAAGTCCGGATAGTAGTAGTGGtgttgttaataattatatagatCCTTATAAATTAATGCAATTAGATCGGAATCGtgatttaatgaattttaatgatttgtcTGACAATCCTAGAATATCCGATTTAGATATTCGTGATAATGGTATTTATGCTAAGGTATTGTTACATCGTGGTGTACGGTTGGGACCGTTTCCAGTGAAATGGTGTAATGAACCAAAGGATAAAAGATATGCATGGGAGgTTGTATCTGGGGCTAATGTTCATGGTTGGCTCGAACCTGCTTTAGAAGTTACAAATTGGTTAAGAAAAATTCGTATTGCTGATAAATCAAAAGAAGcaaatttacacaattttttaaatggatgTTATGTATGGTACGAAGTTTGTAAAGATATTGAAGCTGGTGATGAATTAGTATGTTGTCAAAAACATCCAATAcaattaaaggatatttttcgaGATGATATAATGAATCAATTGGCAATGGATTGTGAAAATAAGCTCAGTGATAGGGAAAGTGTTACTGGATCTCAACATAGTGGTACAACTGGTGAGGACGAATTTAATACGTCTAATGATTTGGATAATAGTAAtagtaacaattttaaaacaaatgaaaatttaaatagaaaatacaataatcgacatagtaataataataataataataatcatcatcataatcatCATTTGCGTCATAACaacagtaataataataataacaataataataattttgatcaaGATACTGATGACGAAGAAGGATTTGATTTTCGTTGTGTTGTATGCGAAAGACAATATCACGATATCGACCATTTAGATGATCATTTAGTAGCTGTTCATCATTACCAAAGGGATGCATATCGGTGTGAATTGTGCTCAAAAAGTTATTGTTATCGACCATCATTATTAAGACATCGTGCTTTATTGCATGGTGAAGCTAGAAAATATCCTTGTGAAAATTGCACAAAGGTTAGTTGTAAAGAgGTATTTTGTGATCCATCAAACCTTCAGAAACATATTCGTTTGCATCACGTAGGTGCTAGAAGTCACGCTTGTCCGGAATGTGGTAAAACATTTGCAACATCTTCTGGTCTAAAACAGCATACACACATTCATTCGTCGGTGAAACCGTTTCAGTGTGAGGTCTGTTTCAAAGCGTAcacacaattttcaaatttatgtcgACACAAACGTATGCACTCTGATTGTCGTACACAAATTAAATGTCAAAAGTGTGGACAAAGCTGTAGTACACAAACTTCATTATCAAAACATAAACGTTTCTGTGATTCAACACAAGCAATACCATCTCATTCACAAGGATCACATCAGCAACAGCAATATCATCATCATTCGAGTGGTATACATTCGCAGCAGCAAACAGAAGGAGGAGGAGTAATAGGTCCACCTCCGCCATTATCAGCAGTAAAACAATCGCAATCAGGAGTAAATAACGGATTATCAGCAGCAGGAATACCAACTGCAATGACTACCCCACCAAATCCATTCTTTATGTTTCGAGGACCTCCACCATTCTTTCCACCCGGTTTTGGGCCATATGGATTGCCTGGTATATTTCCACCTAGTCCAGCACAAGCACCCAGTTTCCCTTTTATGTTTCCGAAACCAAATTTAGAAATGGCAATGTCGGCAGCTGCCGCAGCTGATAAAGATCGAAGTTTTTCACCAAATAGAACAAATGTCGGATATGGAAATTTGAGTAGTAGACTGAATTCAACTGGAGGAGGAGGAGAAGGAAGGTCCGAAgatgataataaattgaataactTGAGACGACCATCACCAGCTAGACCGATTccaatatcaaatataattaaaactgagtcaaaatatgatttatgttcaccgaaaattcaaaatattcaaagttcAGATGACGATACCAATTCATCCGCAATTGATCTAAAAGTTTCGTTTGCCAATAGGgaacaatatttgaaaatcaaaGATGAAGGCATGTCATCAGAAGATAAGttgtCAATAAATGTAACAACTACTCCATCACCTATAAACGAAGGACCTGAAGAAACCGAGgtcacaacaacaacaactccGGAACAACCATTAGATTTATCAGTAACACGTAAACGACCAGCAAGTAAAAGTCTTACACCCGAACCAGAATTACAATTAGAACCGCCAGAACCGAAACGATCTAAATCTCCTTCGCAGAACTCCTCATTTCATACCAGTCCTATGCATTCTGTTTCGCCAGGACCAACTCCATCACCATCTCCACCCGGACCAACAATGGTATGTCCCCGTCCAATACATCCGATTCTCCTAGAAGCAGCTAACTATCGACCACAAACAGCAGCTGATATTTTAGCAGCATTTCAAAGGCCATTTCCTTTTTTAGGTCGGATGGGTAATACAGGGAGAACAAACGGTTTTGATCATATGttacatcatcatcatcaccagCAGCAGCAGCATCATCACCATCAACGAAATGGTTCTATTGGGCCTTTTGCGCCAAAACCTTTTCATGAAGCTTTAATGGCTGCCGGTGGCCTAGCCAATAGTCTTTCAACAACTGGCAAAATAAAAGATCGTTACACttgtaaattttgtggtaaaattTTTCCTCGATCAGCAAATTTAACACGACATTTACGTACCCATACTGGCGAACAAccatataaatgtaaatattgtgAAAGATCTTTTAGTATTTCAAGTAATTTACAACGACATGTCCGCAATATCCATAATAAAGAGAGACCATTTAAATGTCATTTGTGCGATCGTTGTTTTGGTCAACAAACTAATCTTGATCGTCATTTGAAGAAACATGAAGCTGATGCTAGTGGTTTAGGTTTAGGTGTTGGTGATTCACCATCATCTAATGAAGCTGATAGAGAAGATGCATGTTTTGATGAAATTCGATCATTTATGGGTAAAGTAACATATACAGGGGGTATGTATACACCAGTTAGTATAGGTATGGGTGAAAATGAAACAGAAGATGGTAGTGATGTTGATACAGAAATATGTACAGATAAAGATTCATTAACTAATAATGATGCACCAATTGAAGTGTCAACATAA
Protein Sequence: MLFDRYAMSGSSGDEYESTIPHLHHKYTNHLPSHRYHPSAPTVGSGTNIGSSDLNHPTNLKVIPLSPDSSSGVVNNYIDPYKLMQLDRNRDLMNFNDLSDNPRISDLDIRDNGIYAKVLLHRGVRLGPFPVKWCNEPKDKRYAWEVVSGANVHGWLEPALEVTNWLRKIRIADKSKEANLHNFLNGCYVWYEVCKDIEAGDELVCCQKHPIQLKDIFRDDIMNQLAMDCENKLSDRESVTGSQHSGTTGEDEFNTSNDLDNSNSNNFKTNENLNRKYNNRHSNNNNNNNHHHNHHLRHNNSNNNNNNNNNFDQDTDDEEGFDFRCVVCERQYHDIDHLDDHLVAVHHYQRDAYRCELCSKSYCYRPSLLRHRALLHGEARKYPCENCTKVSCKEVFCDPSNLQKHIRLHHVGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHSDCRTQIKCQKCGQSCSTQTSLSKHKRFCDSTQAIPSHSQGSHQQQQYHHHSSGIHSQQQTEGGGVIGPPPPLSAVKQSQSGVNNGLSAAGIPTAMTTPPNPFFMFRGPPPFFPPGFGPYGLPGIFPPSPAQAPSFPFMFPKPNLEMAMSAAAAADKDRSFSPNRTNVGYGNLSSRLNSTGGGGEGRSEDDNKLNNLRRPSPARPIPISNIIKTESKYDLCSPKIQNIQSSDDDTNSSAIDLKVSFANREQYLKIKDEGMSSEDKLSINVTTTPSPINEGPEETEVTTTTTPEQPLDLSVTRKRPASKSLTPEPELQLEPPEPKRSKSPSQNSSFHTSPMHSVSPGPTPSPSPPGPTMVCPRPIHPILLEAANYRPQTAADILAAFQRPFPFLGRMGNTGRTNGFDHMLHHHHHQQQQHHHHQRNGSIGPFAPKPFHEALMAAGGLANSLSTTGKIKDRYTCKFCGKIFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCHLCDRCFGQQTNLDRHLKKHEADASGLGLGVGDSPSSNEADREDACFDEIRSFMGKVTYTGGMYTPVSIGMGENETEDGSDVDTEICTDKDSLTNNDAPIEVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00644479;
90% Identity: -
80% Identity: -