Basic Information

Insect: Empis stercorea
Gene Symbol: Hr39
Assembly: GCA_949752835.1
Location: OX457089.1:8608585-8612080[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 1 3.2e+04 -5.7 7.7 74 168 21 113 2 162 0.40

2 5 0.14 4.5e+03 -2.5 7.8 56 153 183 294 161 322 0.40

3 5 1 3.2e+04 -13.0 17.9 32 159 229 373 225 483 0.60

4 5 8e-11 2.5e-06 28.0 0.3 1 138 564 691 564 700 0.63

5 5 1.6e-79 5.2e-75 254.2 3.2 155 408 639 909 627 909 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	1	3.2e+04	-5.7	7.7	74	168	21	113	2	162	0.40
2	5	0.14	4.5e+03	-2.5	7.8	56	153	183	294	161	322	0.40
3	5	1	3.2e+04	-13.0	17.9	32	159	229	373	225	483	0.60
4	5	8e-11	2.5e-06	28.0	0.3	1	138	564	691	564	700	0.63
5	5	1.6e-79	5.2e-75	254.2	3.2	155	408	639	909	627	909	0.89

Sequence Information

Coding Sequence: ATGTCATCAACAGATATTGGGGATTCGTCCTCAATTAACACTACATCCAGCACGACACATAATGGTTCTTCCAGCCTTCATTCATCAAATATTCACCATCCACCACCAACAACAACAGTAATAAATCCATCACGAAATAATGTTTCTgttacaaatataaaatgtgAAGATAGACTTAATTGCCAACCATTAGCTTCATCAGGACACAATTCATCTATACCATATAATAGTAGtaatatttcatcatcatcatcatcaacagcaagtaataattattttaatggaaTTGGTTCGAGTGGTACAACATCATCTACTAATAGTGGCAGCTGTAGTAGTAGTAGCGGTGGTATACGAATTGCTGTACCAAAATTAGAAGAATCAGATGAATCTGAATCAGAATtaacaaatattgaaaatttaaatgttaatcgtcgtataaataataatcaaaataaaaataatggtcCACGTCCAATGTCATGGGAAGGTGAATTATCTGAACCAGAAAATGAATTAATGGATACAGATAATAGTACATtaaataatcatcatcataatcatcatAATAATCAACATAATAATAGTAATCATGATAAACAACAATTTGATGAATCACAAATGTCAATTAAAGAAGAAGAATCTAAAACGGAATTTGATGAAATTACAGTTGATGATACAATGTTAACAGCACAAATATATTCAACTAGTTTAAAgaaatttcaacaacaacagcaacagcagCATCAGCACCtccagcaacaacaacaacaacagaataatgatattgttaatttgaaatatgaaCCAGGTGGTGGTTGTGGTAATATATCAATACCTATTGTACCAATTTCAATAACAAGTGGTACAACATATAATGatcaaaatttatcaacaacaacaaataatataactggtggtggtggtaatagTGGTTTAAATTCACCATTATTAGCACGTTCAAAAATTTGTTCAACATTATTACCAGCAAATCCAAGTCCTGATTCAGCTATTCATTCCGTTTATACACATAGTTCACCAAGTCAATCACCATTAACATCACGTCATGCACCATATACACCATCATTATCACGTAATAATAGTGATGCATCGCATAGTAGTTGTTATTCATATAGTTCAGAATTTAGTCCAACACATTCACCAATCCAAGGTCGTCATAATATTTATGGTGGCAATGGTGGTGGTGCTAATATTACTGgtacaaattgtaataattataatggaaCAAATACATCATCTTCAACATCATTACATCATTCTGTATTATATCGACCAATTcatgataataatattgaaaatggtACATTAAATCGAcgtaataatgataataatagttGTAGTAATACATCATCTAGTagtacaacaacaacatcagcaacaacaacaacagatatattaattgaaaatgattcaTCTGGTATACCATCACCAGGTATATCACGTCAACAATTAATAAATAGTCCATGTCCAATATGTGGTGATAAAATATCTGGTTTTCATTATGGTATATTTTCATGTGAATCATGTAAAGGTTTCTTTAAACGTACTGTACAAAATcgtaaaaattatgtatgtgtTCGTGGTGGTCCATGTCCAGTAACAATATCGACTAGAAAAAAATGTCCAGCATGTCGTTTTGATAAATGTTTAGTTAAAGGTATGAAATTAGAAGCGATACGTGAAGATCGGACACGTGGTGGCCGTTCAACATATCAATGTTCATATACATTACCAACAACATTAACAATACCCGATAATAATACAACAatgcaaaatttattacaatcaaATTCACGAATGAATGGTTGTATAATTAAGACAGAAGGTGGCAGCAATAGTGGTGGTATTAAAACTGATGGTGGTTATATTAAAACAGAAAATGATAGTGCAGCTGGTATTAGTAGTAGTAATAGTTTAGGAAATCAAAAAATCAATACAGTGCCACCTCTGTTACAGGAAATCATGGATGTTGAACATTTATGGCAATATAATGAATCAGAATTATCACGTTTAAATcaaacatcatcatcatcatcatcatcaacatcatcatcagcagCTAATTTAACAACAAATGCACTACTGGCTAGtgctggtatatcatcaaatgGCGATAATACAAATCCTGATTTAATAGCAACATTATGTAATGTTGCTGATCAtcgtttatataaaattgttaaatggTGTAAAAGTTtaccattatttaaaaatatttctattgatgatcaaatttgtttattaataaattcatggTGTGAATTACTTTTATTCTCTTGTTGTTTTCGTTCAATAGAAACACCAGGTGAAATAAAAATCTCATTAGGTAAAACAATAACATTATTACAGGCTAAAACAAATGGATTGcatgCTTGTGTTGAGAGAATGCTTAATTTGACTGATCATTTACGACGATTGCGTGTTGATCGTTTTGAATATGTTGCCATGAAAGTAATTGTACTTTTACAATctgATACATCAGAACTTCGTGAACCAGTTAAAGTACGACAAAGTCAAGAAAAAGCTTTACAAGCTTTACAAAGTTATACATTAGCACATTATCCAGAAACACCATCAAAATTTGgtgaattattattaagaataCCAGAATTACAGAGAACATGTCAGctTGGCAAAGAAATGTTAACAATTAAATCAAAAGATGGtgaagattttaatttattaatggaATTATTACGTGGAGAACATTGA
Protein Sequence: MSSTDIGDSSSINTTSSTTHNGSSSLHSSNIHHPPPTTTVINPSRNNVSVTNIKCEDRLNCQPLASSGHNSSIPYNSSNISSSSSSTASNNYFNGIGSSGTTSSTNSGSCSSSSGGIRIAVPKLEESDESESELTNIENLNVNRRINNNQNKNNGPRPMSWEGELSEPENELMDTDNSTLNNHHHNHHNNQHNNSNHDKQQFDESQMSIKEEESKTEFDEITVDDTMLTAQIYSTSLKKFQQQQQQQHQHLQQQQQQQNNDIVNLKYEPGGGCGNISIPIVPISITSGTTYNDQNLSTTTNNITGGGGNSGLNSPLLARSKICSTLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHNIYGGNGGGANITGTNCNNYNGTNTSSSTSLHHSVLYRPIHDNNIENGTLNRRNNDNNSCSNTSSSSTTTTSATTTTDILIENDSSGIPSPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVTISTRKKCPACRFDKCLVKGMKLEAIREDRTRGGRSTYQCSYTLPTTLTIPDNNTTMQNLLQSNSRMNGCIIKTEGGSNSGGIKTDGGYIKTENDSAAGISSSNSLGNQKINTVPPLLQEIMDVEHLWQYNESELSRLNQTSSSSSSSTSSSAANLTTNALLASAGISSNGDNTNPDLIATLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIETPGEIKISLGKTITLLQAKTNGLHACVERMLNLTDHLRRLRVDRFEYVAMKVIVLLQSDTSELREPVKVRQSQEKALQALQSYTLAHYPETPSKFGELLLRIPELQRTCQLGKEMLTIKSKDGEDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00643292;
90% Identity: iTF_00644201;
80% Identity: iTF_00644201;