Basic Information

Insect
Empis livida
Gene Symbol
-
Assembly
GCA_963932195.1
Location
OZ010648.1:12451623-12457508[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00076 0.046 14.4 0.4 2 23 221 242 220 242 0.95
2 12 0.0019 0.11 13.1 1.2 1 23 282 304 282 304 0.94
3 12 0.027 1.6 9.5 5.5 1 23 336 358 336 358 0.96
4 12 0.00053 0.032 14.8 0.9 1 23 420 443 420 443 0.97
5 12 0.00038 0.023 15.3 4.2 1 23 477 500 477 500 0.98
6 12 6.1 3.7e+02 2.1 0.4 1 7 511 517 511 521 0.92
7 12 0.0067 0.4 11.4 1.1 2 23 571 593 570 593 0.96
8 12 0.0054 0.32 11.7 7.1 1 23 604 626 604 626 0.98
9 12 0.0038 0.23 12.2 0.1 2 23 664 686 663 686 0.96
10 12 0.0012 0.072 13.7 1.3 1 23 692 715 692 715 0.92
11 12 9.6e-05 0.0058 17.2 2.2 1 23 721 744 721 751 0.96
12 12 2.6e-05 0.0016 18.9 4.6 1 23 784 806 784 806 0.99

Sequence Information

Coding Sequence
ATGAATACGTCAACAATAATAAATGGTCCAgcccaatttaaaaatatttgtcgcGCTTGTCGAAAAATTAACAGAGATATGAGACCAATATTTAATTCTGAAATTAATTCTGTACAAGTATCACAAATGCTTTCCTTTGCTGTTGCAATTAATGTACGACCAGATGACAAACTACCAAAAGCGTTATGTTCGCCATGTTTGAAAAAACTAATAGATACTTATCAATTCCTACAAATGTGTATTGAGTCAGATGAAGAAATgcgtaatattttaaaaaataattttaatgttaaatctGTTATTGTTGAGAAAATACATAATCACCAACagcatcaaaatttattaccattCGCAGCAAAACCATTACTTAAAACtgctttattaaaaaataatgaatttggaaaaataGAAACACCGGTTCAATCACAAGATAATGACAATAATACTCATATTGATGTTATTGAATATGACGGTACActaattaaaTTCGAAAATCAAGATTACGATgaatttgacaattttgaatatggaGGTACTTCTGATAATAGAATTgtagaaacattaaaaatgagAAATCGTAATGAAAATCTGTCACGTgtaactaataaaaatcaagatataatttatagtGCTGACACGAGAATTggatatacaaatttaaaatgtaatttttgtgaaaagcAATTTATACGAAGAGATGATCTGGATAATCATGAAATAATTCACACttcaattaaaaataattcaacttatatacaaaaatccTCAGAATATTCAGATAAAACTATAACAATAAAAGATCGtttttctttaccATCAACCAACGAACCaattattggtaaattttcttGTGCCTTTTGCAAAAATACATTTCACACCTGGGAAAATTTAGCAAAACACATTGgagaacataaaattaaaagtatttatggTACTGATCCaggtaatccAATTGCTGTCAATAAAACTATACCAATGGATATTGAAAAATCGTCAATAACCCCTCATCAATGCACATATTGTTTGAAAAGATTTACTTATCGTGAAGATTTAATTTGTCATATGAACGACCACATAAACGAAATaaacattacaaaacatttagaaaattcttCAGACCAAATAATACAATTAGAAACAATTAGAGAAATTCCAATTGATATTGAAAACGAACAGCCTAGATTATcagaaaaAAATACTGACCCATCATCAGCTGAAAATGATAAAGAACCTTTAGTTGCAAATGATAAACCATCTTATGTATGTCAATATTGTGATGCCAAAATAAGTTatacttataatttaaaacgaCATATTGCAAGGAAACATCCTGAAAGTCTATCTAATGAGATTGTTAGAAAATTAGCAAGTAATTccgaaacaaaaacaaacatcaatgtgttaaattcaaattctaaaataaaaaattacaaatgcAATCATTgcggaaaattatttaaaaaatatttggatatGATTAGACATCGAAAAACTGTTCATACAATtattaaGATTAAAGTGGCTAAAACATATCAATGTCCACACTGTCCAAGTATAATTAAATggagtataaataatttagacaGACATATTAAAAGTGTACATCCACATGTTTCAAACAgcAAATCAGATCATATTCCAATTGCTGTTGGAACACCAGATCCGTccccaattaaaaataaacatataaatttacttaaacaGTTTATAAAATGTCAATACTGTGAGTTGACGCTTTGTAGTAAAGCCGATGTTCAACGACACATAATTAAAATGCATAAAGAATTTGCAAgcattggattaaaaaaatacgaatGCAAATATTGtggaaaaatgtttaaaaaatattttgatatgtGTGGCCATCAAAACCATCATAAAACACGAAATGATCCAATCTTGATACCACAAATTGAATCAAGTGTTATTGATGAAGGCGCAATAGATccattagaaataaataaagcaaataaaaaacatattcctGTACAATGCAATATTTGTCCAGTTGTTTTAcgtaatatttattcttaCAATCGACACATTAAACAAGTTCATGGACTTAAtgaaaaGTTTAATTGTAAACTATGTGTCAAACGTTTTAAAACTCCTAATGCCCTAAATACTCATTTCCTCTTAAATCAtagagaaaaaaGTAAATTCAATTGTGATCAATGTGAGAAATCGTATGAAAGATCTTCGGGTTTAACTAGACATAAGaaacaaaatcataattatgttaaacatattaattCTGCTGCCTTATATCAATCCTGCAGACGACATTATCGATCTGTACAttcagataaaattaatgaatatgaTAATGCCCAAAGGGAAGACCACAAATACAAATGTTCAGATTGTTACAAAACTTTTGGACGaagttataattataaaaaccatACCCAACGGCATTTAGTTTTTGATTTAGACAGTAGCAAAATAGTCCAAGTAAAgagacgtaaaattaaaacagaaGAAATGGAAagcagaaatttaataaaagtggAGGTTGAAAATCATGACAATAATTCAAAGAATATTGATAATGCAAATATAATATCATCAATAATAAACAATGTACAAGAATTAAGATCCCATCTGGAAACTTCAAATACTGTAGAAAATAACGCAACTGAACAATTAATACAGACTGATGTGCctgaacaaaaaaactaa
Protein Sequence
MNTSTIINGPAQFKNICRACRKINRDMRPIFNSEINSVQVSQMLSFAVAINVRPDDKLPKALCSPCLKKLIDTYQFLQMCIESDEEMRNILKNNFNVKSVIVEKIHNHQQHQNLLPFAAKPLLKTALLKNNEFGKIETPVQSQDNDNNTHIDVIEYDGTLIKFENQDYDEFDNFEYGGTSDNRIVETLKMRNRNENLSRVTNKNQDIIYSADTRIGYTNLKCNFCEKQFIRRDDLDNHEIIHTSIKNNSTYIQKSSEYSDKTITIKDRFSLPSTNEPIIGKFSCAFCKNTFHTWENLAKHIGEHKIKSIYGTDPGNPIAVNKTIPMDIEKSSITPHQCTYCLKRFTYREDLICHMNDHINEINITKHLENSSDQIIQLETIREIPIDIENEQPRLSEKNTDPSSAENDKEPLVANDKPSYVCQYCDAKISYTYNLKRHIARKHPESLSNEIVRKLASNSETKTNINVLNSNSKIKNYKCNHCGKLFKKYLDMIRHRKTVHTIIKIKVAKTYQCPHCPSIIKWSINNLDRHIKSVHPHVSNSKSDHIPIAVGTPDPSPIKNKHINLLKQFIKCQYCELTLCSKADVQRHIIKMHKEFASIGLKKYECKYCGKMFKKYFDMCGHQNHHKTRNDPILIPQIESSVIDEGAIDPLEINKANKKHIPVQCNICPVVLRNIYSYNRHIKQVHGLNEKFNCKLCVKRFKTPNALNTHFLLNHREKSKFNCDQCEKSYERSSGLTRHKKQNHNYVKHINSAALYQSCRRHYRSVHSDKINEYDNAQREDHKYKCSDCYKTFGRSYNYKNHTQRHLVFDLDSSKIVQVKRRKIKTEEMESRNLIKVEVENHDNNSKNIDNANIISSIINNVQELRSHLETSNTVENNATEQLIQTDVPEQKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00643413;
90% Identity
iTF_00643413;
80% Identity
iTF_00643413;