Eaen028667.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Elmis aenea
Gene Symbol
ZNF219
Assembly
GCA_947652605.1
Location
OX393577.1:5319998-5321308[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00045 0.058 14.8 3.9 1 23 11 33 11 33 0.99
2 11 1.1e-06 0.00015 23.0 0.3 1 23 39 62 39 62 0.97
3 11 3.6e-05 0.0047 18.2 1.4 1 23 72 94 72 94 0.98
4 11 6.2e-06 0.00082 20.6 1.8 1 23 100 122 100 122 0.98
5 11 0.00021 0.028 15.8 2.7 1 23 128 150 128 150 0.98
6 11 6.6e-06 0.00087 20.5 3.0 1 21 156 176 156 179 0.95
7 11 1 1.3e+02 4.2 5.1 1 23 185 205 185 205 0.96
8 11 1.8e-06 0.00024 22.3 1.0 3 23 213 233 212 233 0.99
9 11 5.5e-06 0.00072 20.8 1.9 1 23 239 261 239 261 0.99
10 11 0.82 1.1e+02 4.5 0.6 9 21 276 288 267 291 0.88
11 11 0.77 1e+02 4.6 2.9 1 20 297 316 297 318 0.92

Sequence Information

Coding Sequence
ATGACTTACGCCAAAGAGAAACCACGAAATTATCAATGCGAAACTTGCCATAAAAAGTTTTTAGGTAACAATGATCTGCGAAAACATCGACGGATACATACAAACGAACGACCTTATGTTTGCAAGGAGTGTAACAGGGGATTCCGGCAGGCCGGGTCCCTGAAGAACCACATCGTAACGCAGCACTCTTCGGGTCTGCAAAATCCCGAGATTTTCGTTTGCAATTATTGTCACAAACCgtttcccattaaagaacgtctgagattacatttacgtatacatacaggggataagccgtactcttgcaagcattgcccgaagacgttcgcacgtggtgggcaattggttcagcataataggacccatacggggtctcgtccgtacgtatgcaaggaatgcgattcgacgttcacatgttcggctaatctaaaattacacattaaacgacaccaggaaattagggactacgtttgtgacgtatgtggcaagagtttttttcggagagacgctttaaaaaaacatttgaactgttttcacgcaaacgtcaaggcgtttcattgtaaagtttgcaataaaatgttgaagggtcatttgccacagcatatgcggacgcacaaaaaagacaaaccccacggatgtgcgcactgtggagccagattcgcacaacgatcgcagttaacggtgcatcaacgtactcatagcggagaaaagccgtacagatgtcaagtctgttggaaagctttcgcccattcgaccgcccttaaacttcacaccagacgtcacacgggcgagaaacccttcgtctgcatattatgcaaaagttcggctttctcccagttaccacatctaaagaagcatatgcTGTGTATACATAAATCAAACAAACCGTACGTTTGTCCTCATTGCAAGTCATTTCACAGGACGAAAAACGATTTAGAAAATCACTTTTTGAAATGTAAAGTATTCAAAAAATTACCAAAAATCGAACCAAAGATTGAATTCGCTAACATTGACCCACCTATGGCTATCGAAAAAATGCGCCTACTATTAGCAATCTTGCTAAAAAAGATCTCAGCACCGGAACGATTGGACGAGTTGGGTTTCAACAAGAGACTGATCGATGATGTTCTTATCGAATCGATCGAGAGTTCGGGGCGGGAGCCTTGCAAAGATTATACATTATCAGCGGCTGAAAAATTGAAACGTAACGTACAAATATTATTAGAATGGACTGTACCTAAACATTACATGGAGAAGTTTAAAACTGAACAGCGTTCTACTGAAGAACTGCTAGAAGAGTTAACCTCTTAA
Protein Sequence
MTYAKEKPRNYQCETCHKKFLGNNDLRKHRRIHTNERPYVCKECNRGFRQAGSLKNHIVTQHSSGLQNPEIFVCNYCHKPFPIKERLRLHLRIHTGDKPYSCKHCPKTFARGGQLVQHNRTHTGSRPYVCKECDSTFTCSANLKLHIKRHQEIRDYVCDVCGKSFFRRDALKKHLNCFHANVKAFHCKVCNKMLKGHLPQHMRTHKKDKPHGCAHCGARFAQRSQLTVHQRTHSGEKPYRCQVCWKAFAHSTALKLHTRRHTGEKPFVCILCKSSAFSQLPHLKKHMLCIHKSNKPYVCPHCKSFHRTKNDLENHFLKCKVFKKLPKIEPKIEFANIDPPMAIEKMRLLLAILLKKISAPERLDELGFNKRLIDDVLIESIESSGREPCKDYTLSAAEKLKRNVQILLEWTVPKHYMEKFKTEQRSTEELLEELTS