Basic Information

Gene Symbol
-
Assembly
GCA_947532085.1
Location
OX383934.1:19122814-19141879[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 3.8e-05 0.0029 18.8 2.9 1 23 428 450 428 450 0.97
2 21 0.0054 0.41 12.0 0.6 1 20 456 475 456 478 0.94
3 21 2.7e-05 0.0021 19.2 5.6 1 23 497 519 497 519 0.98
4 21 0.00013 0.0096 17.1 4.1 1 23 525 547 525 547 0.99
5 21 4.6e-05 0.0035 18.5 5.3 1 23 553 575 553 575 0.97
6 21 1.2e-05 0.00094 20.3 7.9 1 23 581 603 581 603 0.97
7 21 6.6e-07 5e-05 24.3 3.0 1 23 609 631 609 631 0.98
8 21 0.00013 0.01 17.1 6.7 1 23 637 659 637 659 0.97
9 21 0.00013 0.01 17.1 6.5 1 23 665 687 665 687 0.97
10 21 6.3e-07 4.8e-05 24.4 1.9 1 23 693 715 693 715 0.98
11 21 6.5e-05 0.0049 18.1 7.9 1 23 721 743 721 743 0.98
12 21 7.4e-05 0.0057 17.9 7.8 1 23 749 771 749 771 0.97
13 21 9.3e-06 0.00071 20.7 5.4 1 23 777 799 777 799 0.98
14 21 1.8e-05 0.0014 19.8 2.1 1 21 805 825 805 826 0.94
15 21 3.1 2.4e+02 3.3 0.8 12 23 828 839 827 839 0.91
16 21 3e-05 0.0023 19.1 7.3 1 23 868 890 868 890 0.97
17 21 4e-06 0.0003 21.9 6.0 1 23 896 918 896 918 0.98
18 21 4.7e-05 0.0036 18.5 8.3 1 23 924 946 924 946 0.97
19 21 9e-06 0.00069 20.8 5.1 1 23 952 974 952 974 0.98
20 21 0.00071 0.054 14.8 0.3 1 23 981 1003 981 1003 0.96
21 21 0.36 28 6.3 4.2 1 23 1012 1034 1012 1034 0.98

Sequence Information

Coding Sequence
ATGAATCCTGAGCACCACAGTATCAACACGGGTGGTGGCCAGCCTCCTGGAAGTTCTGAGTCTCAAAATCAAAGGATTCAGAATGCCCAGCAGCAACAAGGCAATAACTTGCCCGCCACGACGTCAGCGACAGACTTGCGAGTGAATTCTGTAAATTCGGCTGCCGTAAACGTCGCTTTGTCTAGCGTCGCCAAATACTGGGTGTTTACAAATCTTTTCCCGGGTCCAATACCTCAAGTTTCTGTGTATGGACTTCCCACAGGCACAAGAATCGAAAATGGAAAACCAGTCCAGGATTTGGGACAGGCCCATGCCAGCATCCTCAATGGAGATCCCAACATCATACTTGGACACCACACTGGGCAGCCACAGGTCACGGTGTCTGCAGCTGGTGCACAGCAGATACCAGTATCTCAAATTATTGCAGCACAATCTGGACAGACTCATGAAGCACTTGTGGCCCACAGTCAACAGCAAGAGTTGGCTGCGCAGCAGGCATCGGGTGGATCTCAGGTCACAGCAACGCACCAGCAGGTACCCAATAGTCGGGTCGAGTTTGTACAACACCATAACATTGATATGGTAAATCACGTGGGGCATCATTCACAACAGCATTTGATGCAGCAGCAACTGATGGCTGGAGCACGTCAGGAACACACAAATCAACAGATCCAACTTACTGTCAGTGAAGATGGCATTGTGACAGTAATGGAGCCTGGTGGCGGGAAGCTGGTGGACAAGGAGGAGCTGCATGAGGCCATCAAGATGCCCACGGACCACCAGACACTTACTGTTCATCAATTACAGCAAATTGTTGGACAGCAGGTTATAGATAGTGTAGTCCGTATCGAGCAAGCCACGGGTGAGCCAGCCAACATCCTAGTGACGCACAACCCTGACGGCACCACGTCCATCGAGGCGAGTGCCGCGGACCCACTTATAGTGAAGGATGAGAAGAATTCAGGCAAGATTGAAACTGCACAGTTCGCCATCCCGGCGGAGATAAAGGACATCAAAGGAATCGATTTAAAGAGTGTAGGTGCTATGGGCATGGAGGGAGCTGTAGTGAAGATATCCGCTGCAGCTACAGACCACGATCTCCACGCGATGTATAAAGTCAATGTGGAGGATCTCTCACAGCTACTGGCCTATCATGAAGTGTTTGGGAAGCTGAACACAGATGGGCAGCAACAGACAAAAGTCATTAGTGGTGGAGTCGAGGTGGAGGTAGAGGCCGGTACGAGCGCCGCTATGTCTGAGTCAGAGTCATCGCCGGGACAGCACTCCTGCGACATCTGTGGCAAGAGCTTCCAGTTCAGATACCAACTCATTGTTCATAGACGATATCACGGCGAGAGCAAGCCGTTCACGTGTCAAGTATGCGGCTCTGCTTTTGCCAACCCTGTGGAGCTATCTAGGCACGGAAAATGTCATCTTGCTGGTGACCCAGCCGAACGCAACGCCAAGAGATTGACGCAAGACAAACCTTACGCTTGCACTACTTGCCATAAAACGTTCTCGCGTAAGGAGCACTTGGATAACCACGTCCGTAGCCATACTGGAGAGACACCTTACAGATGCGAGTTCTGCGCCAAAACATTCACGCGTAAGGAGCATATGGTGAATCACGTCCGCAAGCACACGGGGGAAACTCCACACAGATGCGAGATCTGCAAGAAGAGCTTCACCAGGAAGGAGCACTTCATGAATCACGTCATGTGGCATACAGGTGAAACGCCGCACCATTGCCAAATATGCGGCAAGAAGTATACTAGGAAGGAGCATTTAATGAACCATATGAGGTCGCACACAAACGATACTCCATTCCGATGCGAACTATGCGGCAAGTCGTTCACGAGAAAGGAACACTTCACCAATCACATTATGTGGCATACGGGCGAGACACCCCATCGCTGCGATTTCTGTTCAAAAACGTTCACTCGCAAGGAGCACCTACTGAATCACGTGCGACAGCACACAGGCGAGTCCCCGCATCGCTGCAACTTCTGCTCCAAGTCGTTCACGAGGCGAGAGCACCTCGTCAACCACGTGAGACAGCACACCGGAGAAACTCCCTTTCAGTGCGGCTACTGTCCCAAAGCATTCACTAGGAAAGACCACCTTGTGAACCACGTCAGACAGCACACTGGAGAATCGCCGCATAAATGTTCCTTCTGTACAAAATCGTTCACTCGAAAAGAACACCTAACCAATCACGTGCGTCAGCACACGGGTGAATCCCCGCACCGCTGTACCTTCTGTTCCAAGTCCTTCACGAGGAAAGAACACTTAACCAATCATGTCAGACAGCACACGGGCGAAACTCCACACAAGTGCACGTTCTGCCCGCGCGCATTCTCACGTAAGGAGCATCTCAACAACCACATCCGCCAGCACACCGGCGACATGCCGCACTCCTGCACTTACTGCAGCAAGAGCTTCACCCGCAAGGAACATCTCGTCAACCACATCAGTATTGAGAACAAGCAGCAACTCAACAACCACATCCGGCGACATGCCGCTCTCCTGCACCAACTGCAGAAAGAGCACCCACAAGGAGCATCTTGTAACCACATTAGACAACACACAGGCGAAACCCCGTTCAAGTGCACGTACTGCACGAAGTCGTTTTCGCGCAAGGAGCACCTCACCAACCACGTGCATCTGCACACCGGGGAGACGCCGCACAAGTGCCCCTTCTGCACCAAGACCTTCTCCAGGAAGGAACACTTGACCAACCACGTCAGGATTCACACGGGCGAGTCCCCGCACCGCTGCGAGTTCTGTCAGAAGAGGTTTACGCGTAAAGAGCACCTCACGAATCATATGAAACAGCATACAGGAGATACACCACATACATGCAAGATTTGTTCAAAACCTTTCACGAGGAAAGAACACCTAGGAACGCACATGAGATCACACAGTTGCGGAGAACGACCATACAGTTGCGGAGAGTGCGGAAAATCTTTCCCACTGAAAGGAAACCTGCTGTTTCACGAACGCTCGCACAACAAGACGGCCGGGGCGAGGCCCTTCCGGTGCGACGTTTGTTCCAAGGACTTCCTTTGCAAAGGTCACCTGGTGGCGCACCGGCGGACGCACGGCGAGGCGGGCGAGTGCGAGGCGCCGGCCGGAGACGACTGCGGCGACCCCGCCAAGTGCGACAAGCAGGACCCGCCCGAGAGGAAGCACGATATCATGACAACAGTTGAAAACAGGCCAGCAGAAACGACGAATGTGCAAAACCCCCAAAACAACACAAGTGTGATGCAAATAACGACACAGCAAGTCCGCGCAGTGGCGCCGAGCGGGCCAGAGCCGAGCGCGGGGTTCGCGCAGCAAGCTGGCACCGCGCCCGCACTGCACCACCCCGTGTCCGTCACCTACTAG
Protein Sequence
MNPEHHSINTGGGQPPGSSESQNQRIQNAQQQQGNNLPATTSATDLRVNSVNSAAVNVALSSVAKYWVFTNLFPGPIPQVSVYGLPTGTRIENGKPVQDLGQAHASILNGDPNIILGHHTGQPQVTVSAAGAQQIPVSQIIAAQSGQTHEALVAHSQQQELAAQQASGGSQVTATHQQVPNSRVEFVQHHNIDMVNHVGHHSQQHLMQQQLMAGARQEHTNQQIQLTVSEDGIVTVMEPGGGKLVDKEELHEAIKMPTDHQTLTVHQLQQIVGQQVIDSVVRIEQATGEPANILVTHNPDGTTSIEASAADPLIVKDEKNSGKIETAQFAIPAEIKDIKGIDLKSVGAMGMEGAVVKISAAATDHDLHAMYKVNVEDLSQLLAYHEVFGKLNTDGQQQTKVISGGVEVEVEAGTSAAMSESESSPGQHSCDICGKSFQFRYQLIVHRRYHGESKPFTCQVCGSAFANPVELSRHGKCHLAGDPAERNAKRLTQDKPYACTTCHKTFSRKEHLDNHVRSHTGETPYRCEFCAKTFTRKEHMVNHVRKHTGETPHRCEICKKSFTRKEHFMNHVMWHTGETPHHCQICGKKYTRKEHLMNHMRSHTNDTPFRCELCGKSFTRKEHFTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCTFCSKSFTRKEHLTNHVRQHTGETPHKCTFCPRAFSRKEHLNNHIRQHTGDMPHSCTYCSKSFTRKEHLVNHISIENKQQLNNHIRRHAALLHQLQKEHPQGASCNHIRQHTGETPFKCTYCTKSFSRKEHLTNHVHLHTGETPHKCPFCTKTFSRKEHLTNHVRIHTGESPHRCEFCQKRFTRKEHLTNHMKQHTGDTPHTCKICSKPFTRKEHLGTHMRSHSCGERPYSCGECGKSFPLKGNLLFHERSHNKTAGARPFRCDVCSKDFLCKGHLVAHRRTHGEAGECEAPAGDDCGDPAKCDKQDPPERKHDIMTTVENRPAETTNVQNPQNNTSVMQITTQQVRAVAPSGPEPSAGFAQQAGTAPALHHPVSVTY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01030446;
90% Identity
iTF_00073027;
80% Identity
-