Ecan055355.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eilema caniola
Gene Symbol
egg
Assembly
GCA_949126895.1
Location
OX421490.1:6403110-6424401[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.9 1.5e+04 -2.6 0.1 29 38 296 305 271 306 0.83
2 2 2.5e-14 1.9e-10 41.9 0.1 4 70 337 396 334 402 0.87

Sequence Information

Coding Sequence
ATGCAAGTATATGCCATGAAGAACGCCTTCGGACCCTGGTTCATGGGCAAAATACTGGAGATTATACCCAAGAGCAGTAACCCTGCAAATTTCACGATGTGCCGCATTAAATTTGACCATAAAGTGAAGAATAACGGCAAGGTTCTGCCAGCGAGGTGCATAGCATACGCTGAGCCGGCCGATGTGAGAATGACTATCGGTACACGTCTCATAGCGCTGTTTAAAGACTCTAACAAACGCGAGTCTTACTATTCCGGTGTGGTCGCGGAGATTCCTAACCCTGTCAACAACTATAGGTATCTAGTATTCTTCGATGACGGTTATGCGCAGTATGTCAGTCACTCCTACACTCGTCTGGTGTGTGAGTGTTCACCCATGGTGTGGGAAGAGGTACACCCACTGTCGCGGGAATTTGTGCGGGAATATCTCCTAGCGTACCCGGAGAGGCCCATGGTGAGGCTACATGAGGGACAGCATCTCAAGACTGAGTGGGACGGCAAATGGTGGTCCTCCCGAGTAAACAAAGTGGACGCGTCTCTCGCACAAGTGGTGTTCATCGGTGACGGCCGTAGAGAGTGGATCtaccgcggctccacccgcctgGCTCCATTGTACCTGGAGCTGAGGGCCGCTGAGAGGCACAGGATTAGGCCTATGCCTCGTAGTACGCAGCCACGGTCTAACATGATGCCGTACGTAGAATACACCCGTTCCGATGAACAAGCTAAGGCTCAAGAAGCACATCCCGTACCTGTGGCGTTGACGGCACAACAGCAGAATGAGGAGCTTCGTCGTCAACGTGCCGTGGCCAAGAAATCCACAAGCCTAGCAAGCGCCCCAGCGCCTCCTGCCCCGCCGCCCGTGCCAAGATCTAACCTGGATTCCCTCACCAGCAGGGTCGTGTACTACACGCCTAAGAACGCAGTGAAGCCTTACAAGCTAGTGCCTCACACGTGTTCGCCCAAGTGCAAACGGACCGACCTACTGACCCTCAAGGAACTGAGGACTTACAACCCGCTAGCAAAACCGCTGCTCAGTGGATGGGAGAGACAAATCGTCCGCTACAAGGGCCAGAAGGAGGTGATGTACCGCGCGCCGTGCGGCCGCCGCCTGCGCAACATGCGCGAGCTGCACCGCTACCTGCGCCTCACTGACAGCGAGCTGCCCGTCGACCTGTTCGACTTCTACTACGTCACGCACTGCTTGGCGGAGTTCGTGCTTAACAAGTGTCTTGTTGGGAAAAAGGACCTGTCTCACGGCAAAGAAAACGTGCCGGTACCGTGCATCAACTACTATGACGACACATTACCTGAGTTCTGTTCGTACAACACGGAGCGGACCCCCACCTCAGGGGTCCCGCTCAACCTAGACCCCGAGTTCTTGTGTGGCTGTGACTGTACCGATGACTGTGAGGACAAAAGTAAATGTGCGTGTTGGAAGATGACGCTAGAGGGCGCTCGCACCATCGGCCTGGATGTCAACAACGTGGGCTATGAGTACAAACGGCTGCCGGAACCGCTGCCTTCAGGCATCTACGAGTGTAACTCTAGATGTAAATGTAAACAGACCTGCTTGAACCGAGTCGCTCAGCATCCGTTGCAGTTGAAATTAcagGTATTCAAGACATTAAACCGCGGTTGGGGTATCCGCGCTCTGAACGATGTACCTAAAGGCTCGTTCCTGTGCGTGTACGCAGGGAACTTGCTCACCGACGCCACCGCTAACTTGGACGGTTTGAACGAAGGAGACGAATACCTCGCCGAGCTGGACTACATCGAGGTGGTGGAGCAGATGAAGGAGGGCTACGAGGAGGAGGTCGCCGAGCCCGACAAGAAACTTGACAAGAAGGAAGGCGCCAAACAAGAAGATTCAGAAGAGGAACCTTCTTCATCATCGGAAGAAGATGACACCGCGTCCAAGACCGACAAGGAAGATGATGATTTCAGGCCCGGCTGTATCTCACTTGGCGTCACGGACTTTAAtaaACGCCTCCGCAAGCGCTCCAAAAAGAAAGAACAGAGCGAAGCAAAGGATGCAAAAGATAAAGACAAGGAAAGTAAACCAACGGAACGGAACCCCGACGAGGATTGTATCACCATCAGTGATGACGACGAAGTTCGTGAGCCGTCCAGGTTCAATGCGAATCCTGGTATGGGCGGGAGCGACTTCATATCTAAGTACAGATCCGTCCGCACGTTGTTCGGCGAGGATGAGGCGTGCTATATCATGGACGCTAAGGTTCAGGGCAACATTGGACGCTATCTAAACCACTCGTGTTCCCCCAACGTGTTCGTCCAAAACGTATTCGTGGACACCCACGATCCACGTTTCCCATGGGTGGCATTCTTCGCGCTGTCCCATATTAAAGCGGGGATGGAACTCACATGGAACTACAACTACGACATCGGTTCCGTGCCCGGGAAAGTCTTGTATTGTTACTGCGAAGCGCCCAACTGTAGAGGCCGACTATTGTAA
Protein Sequence
MQVYAMKNAFGPWFMGKILEIIPKSSNPANFTMCRIKFDHKVKNNGKVLPARCIAYAEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVSHSYTRLVCECSPMVWEEVHPLSREFVREYLLAYPERPMVRLHEGQHLKTEWDGKWWSSRVNKVDASLAQVVFIGDGRREWIYRGSTRLAPLYLELRAAERHRIRPMPRSTQPRSNMMPYVEYTRSDEQAKAQEAHPVPVALTAQQQNEELRRQRAVAKKSTSLASAPAPPAPPPVPRSNLDSLTSRVVYYTPKNAVKPYKLVPHTCSPKCKRTDLLTLKELRTYNPLAKPLLSGWERQIVRYKGQKEVMYRAPCGRRLRNMRELHRYLRLTDSELPVDLFDFYYVTHCLAEFVLNKCLVGKKDLSHGKENVPVPCINYYDDTLPEFCSYNTERTPTSGVPLNLDPEFLCGCDCTDDCEDKSKCACWKMTLEGARTIGLDVNNVGYEYKRLPEPLPSGIYECNSRCKCKQTCLNRVAQHPLQLKLQVFKTLNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEEVAEPDKKLDKKEGAKQEDSEEEPSSSSEEDDTASKTDKEDDDFRPGCISLGVTDFNKRLRKRSKKKEQSEAKDAKDKDKESKPTERNPDEDCITISDDDEVREPSRFNANPGMGGSDFISKYRSVRTLFGEDEACYIMDAKVQGNIGRYLNHSCSPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGMELTWNYNYDIGSVPGKVLYCYCEAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00282417; iTF_01152181; iTF_01332730;
90% Identity
-
80% Identity
-