Egri004899.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ectropis grisescens
Gene Symbol
METTL4
Assembly
GCA_017562165.1
Location
chr19:17326954-17338994[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.00017 0.0099 16.3 1.2 1 23 21 43 21 43 0.99
2 13 6.9e-05 0.0039 17.6 2.4 1 23 49 71 49 71 0.99
3 13 1.3e-05 0.00071 19.9 0.3 2 23 78 99 77 99 0.97
4 13 2.7e-07 1.5e-05 25.2 2.6 1 23 105 127 105 127 0.99
5 13 3.4e-05 0.0019 18.6 4.0 1 23 133 155 133 155 0.99
6 13 0.00015 0.0085 16.5 0.2 1 23 161 183 161 183 0.99
7 13 5.5 3.1e+02 2.2 2.6 15 23 194 202 193 202 0.95
8 13 0.00019 0.011 16.2 4.4 1 23 208 230 208 230 0.99
9 13 2.1e-06 0.00012 22.4 1.3 1 23 236 259 236 259 0.97
10 13 0.013 0.74 10.4 2.0 1 23 265 287 265 287 0.99
11 13 4.1e-05 0.0023 18.3 0.6 1 23 293 315 293 315 0.99
12 13 7.8e-05 0.0044 17.4 0.4 1 23 321 343 321 343 0.99
13 13 0.00069 0.039 14.5 2.8 1 23 349 371 349 371 0.98

Sequence Information

Coding Sequence
ATGGAAGTAATTCCTATAAATCATTCTTTAAATGAAGCAACATACTCTGGGATAAAACTCTATAaatgtgttatgtgtgaatataCAGCAAAAGAAACAagttctttaaaaaaacatatcagaACTCACACGGGTGAAAAACCATATGAGTGTCATTTGTGTAAATTTGCAACATCGCAAACTGCTAGCTTAAAACGACATATCAGGATGCATACTGGAGAACAACCCTTGAAGTGTGATATCTGTGATTTCAAGACCACAGGGgcaagtaatttaaaaatacacataagaACACATACTGGCGAGAAACCTTACAAGTGTGACATTTGTGATTATACATCATCACAACCCCACAACTTAAAAAGGCATATTAAAACACATACAGGAGAAAAAccttataaatgtcaaatatgTGATTTTAAAACCACAGACTCGAGTTATTTGAAACATCATGCCAGGACACATACTGGGGAAAAACCTTACAAATGTGAGTTGTGTGACTATGCCGCAGCTCAattaaacagtttaaaaaatcaTATGAGCACACACACAGGTGAAAAACAATATGAATGTGACATCAATTTAAAACATCACATTAGAACTCACACTGGGGAAAAGCCATATAAATGTGATAGATGTGATTATAAAACTGCACAGATGAGCtgcttaaaaaaacatataagaaCACACACAGGACAAAAACCATATGAGTGTAACATATGTGACTACACAGCAAAACATTCAAGTAACTTGAAACGACACATTATTAAGGTCCACACTGGGGAAAAGCCATATAAATGTGAGTTGTGTGATTTCAGAGCATGTGACACAGGTGATTTAAAGTATCATTTAACTACTCATACAGGAGAAAAACCCTTTAAATGTGATATATGTGATTATAAAACAGTTCTAGCGGGTACTTTAAGGAAACATTTGAGGACACACACTGGTGAGAAGCCTTATAAGTGTGATTTGTGTGAATACCAAGCAACACAAGCCGGTACTTTAAAAAGGCATATGTTGACACACACAGGAAATAAACCATTTAAATGTGACATGTGTGATTATAAAACAATACAAGCAAGTTGTTTAAAACAGCATGTTACAACTCATGTTGTGACTGAAACGATCAGTATAAAAATAGAGAATCGGAACATGGCTGTTAAGTACCGAAGCAGTAATTGCATATTCTTAGATCACGCGAAATTCGTTAATACCCTTTACAAAAATACGACTGTTGACAAAGATACTCATGCATACGAACTTCTACGGAACTTATTTTCTATTCAAAACAACAAGAAAGCAGGACACAGGAAACGAAGTCATAACTCTAATGGATTCTTAGAAGAAACATCGACAGTAAAACAAATGTATGAGCAGTTTTTAATTGAACTTCCCACAGAGTTCAAAGAATCGTTAGCAGGTGCAGAAACAGTGGATACGTCGTCGGTTCGAGACCTGTCCAAGGAGTTGTTTGAATCTACATTGTTTGAACATGACGGGATCAGTGGAGGAAACAATTCTGATTCTTCTTTGAAATATCCGATTAAGGACGAAGATTTTTTAATACCACAAAATTCaagGTTTTTCTGTGGCTGCGTCAAAGAGCAATGCAAAAAACTCAAAGGTACTCGGTTTGATATCGTAATAGCGGATCCGCCGTGGTGGAACAAATATATAAGGAGACTCAAAAGCGCTAACGATAAATTAAGTTACTCAATGATGTACAACGAAGACATTGCCTCGATACCAGTAAAGGACCTACTCTCTTCCAACTGTATCATAGCCGTGTGGTGTACCAACGCTCCAAGCAACATAGACGCTGTCAAAAAACACTATATTCCCTCAATGGGGAGTCACTTACGTCACCACTTGGTATTGGATGAAGGGAAAGTTGGAGATGTAGAAGTGCCTGACAGACAGTTGATAGTGAGTGTGCCAAGCGCTTTACATTCACATAAGCCACCTTTATTAGATCTCCTTGCCCCATTAGCAAAGACAGAAAATCCACAAACATTGGAACTGTTTGCAAGATACCTCCTTCCCAATACGACGAGTGTTGGATTTGAACCCTTGAAGTGGCAACATGTTTCGCTCTTTGATAAAGTTTCTTGA
Protein Sequence
MEVIPINHSLNEATYSGIKLYKCVMCEYTAKETSSLKKHIRTHTGEKPYECHLCKFATSQTASLKRHIRMHTGEQPLKCDICDFKTTGASNLKIHIRTHTGEKPYKCDICDYTSSQPHNLKRHIKTHTGEKPYKCQICDFKTTDSSYLKHHARTHTGEKPYKCELCDYAAAQLNSLKNHMSTHTGEKQYECDINLKHHIRTHTGEKPYKCDRCDYKTAQMSCLKKHIRTHTGQKPYECNICDYTAKHSSNLKRHIIKVHTGEKPYKCELCDFRACDTGDLKYHLTTHTGEKPFKCDICDYKTVLAGTLRKHLRTHTGEKPYKCDLCEYQATQAGTLKRHMLTHTGNKPFKCDMCDYKTIQASCLKQHVTTHVVTETISIKIENRNMAVKYRSSNCIFLDHAKFVNTLYKNTTVDKDTHAYELLRNLFSIQNNKKAGHRKRSHNSNGFLEETSTVKQMYEQFLIELPTEFKESLAGAETVDTSSVRDLSKELFESTLFEHDGISGGNNSDSSLKYPIKDEDFLIPQNSRFFCGCVKEQCKKLKGTRFDIVIADPPWWNKYIRRLKSANDKLSYSMMYNEDIASIPVKDLLSSNCIIAVWCTNAPSNIDAVKKHYIPSMGSHLRHHLVLDEGKVGDVEVPDRQLIVSVPSALHSHKPPLLDLLAPLAKTENPQTLELFARYLLPNTTSVGFEPLKWQHVSLFDKVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00635937;
90% Identity
iTF_00635937;
80% Identity
iTF_00635937;