Esim010445.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ecitophya simulans
Gene Symbol
Rfx2
Assembly
GCA_027574965.2
Location
JAODGE020016000.1:4038-8615[+]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.2e-38 3.7e-34 117.5 0.0 3 78 257 332 255 333 0.97

Sequence Information

Coding Sequence
ATGGCAACGGCAGCAAGGTTCGCCGGCAGTGccgctggtggcggcggcggcggcagcaatccgcccacgccggcgccggccaccacgccgccgacgcccgccgccacgACGACGCAGCTCATCGTCCTCCCCGCCGGCCTGCATCAGACCGGAACGGCGATCGTTAACGCCAACGGCGTGCCGGTGCTGGACGTCGCCGACCTCGACCACGGCGCCGACTCCAGCAACGAGAGCACCGCGACGGAGCCCAGGGGCGGCGAGCCGCACGAGGCGGATCCACTGGCCCTCGGCGAGGAGTCGCCGCACTTCATCACCGTCACCGAGGCCACCGCGCGTTCGTACGCTTCGCTCACGCCCGTGCAGCCGACCGTAGAAGCTGAAGCGGTGGCTTCCCATCCGAACTATCAAGTGCAATATGTTGATACCGAGTTGTATGCGTCTCCAGCGAATGGCGGTCAAGCACAAATGGCGTACCCGGTGTATTCCGTCGGAGAAGGCACGATTTACGCGGCGAGCCAGGGGCAATACTACGCGACGCACGCCACGAACtccggcgcatccaccacaGTGGGGTATGCGACCACCGCAGGACATTACATCGTCCAACAGAccgtcgacgccgatgcgCTCATTGCGTCCACGAGGAATTCGCCGCAAACAACCAACGCCGAGACGAGTTATGTGGCGACTGCCACTGTGCatgcgacgccgtcggcggtggGCGAAGAGGTCGGCTCGGCGCTGAGTCACGCCACCCGAGTCTCGCCAGCGACCGTGCAATGGCTGCTGGAGAACTACGAGACCGCCGAGGGCGTCTCGCTGCCGAGGTCGACGCTGTACGCGCATTACCTGCGCCACTGCAGCGAGAACAAGCTGGAGCCCGTCAACGCCGCCTCCTTCGGCAAGCTGATACGGTCGGTGTTCCTCGGTCTGCGCACGAGGCGGCTGGGCACGCGCGGCAACTCCAAGTACCACTACTACGGCATCCGAGTCAAGCCGGGATCGTCGCTGACCACCGTCGAGGACGCGCCGGGCAGGACggtcgcgacgaacgcgcaggGCGGCaaatccgccgcgcgcggctacaAGAggggcgccgacgcgctggaGCAGAACATGaacgcgggcgtcgcgccggcgcaccTGACTTACCTGGGCGACGGTAACAACGCGATCCCGCTGTTCCCCGACATCgagttcgccgcgccgctgccggaCGAATGCAGttacgacgacgtcgacaccCTGAAGTCGATTTATCGCGAGCACCTCGAAGCGTTCCTCGACGCCATCCTCAGCCTCGAGTTCGGCACGATCGAGTCGCTCTGGCGCGAGTTCTGGCGGTCGCaggacaacaacaacggcgagGAGTGCGAGGAGGAGAAGTACCTGTCGAAGGCGAAGCTGTTCGCGATGTGCGCGCAGGAACCGATGCAGGACTTCGTGCGGCAGGTCGACCTGACCTTCTACCAGAACCTGATCCAGGTGCTCGTCCCCGACGTGCTCAAGCCGATTCCGGCGTCGCTCACGCAGTCGATTCGCAACTTCGCCAAGAGCATGGAGTCGTGGCTGACGACGGCCatggccggcgcgccgcccggcatGCTGGCGGTGAAGCtgtccgcggcggcggcgttcagcTCGAGCCTGCGGCGCTACACGTCGCTGAACCATctggcgcaggcggcgcgcgccgtgctgcACAACAGCACGCAGATCACGCAGATGCTGGCGGACCTGAATCGCGTCGACTTTCAGAGCGTGCGCGAGCAAGCGTCCTGGGTGTGTCAGTGCGACAACGACATCGTCGCGCGGTTCGAGGCCGACTTCAAGCTCACGCTGCAGCAGCAGAACTCGCTGGAGCAGTGGGCGTCCTGGCTGAAGAACGTCGTCAAGAGCGCGCTGAAGCCCTACGAGGGGAAGCAGAGCTTCTCGAAGGCGGCGCGACAGTTTCTGCTGAAGTGGAGTTTTTACAGTTCGATGGTCATTAGAGACTTGACACTTCGCTCCGCCGCCAGTTTCGGCTCGTTCCATCTCATCCGCCTGTTGTACGACGAGTACATGTTTTACTTGATCGAGCATCAGGTGGCCGAGGCCACCGGCATCGTGCCGATCGCCGTCATGGTGGAAGGAATCAAACAAGATCATCTGTCGAACAACATGAGCGTCTACGGCTCCGACGCTGTGTGCAACGGCGGCTCGTCGATGAACGTCAAGCTCGGCTGCGTCAGTCCGTCGGACCCCACGAAGCGCATGAAGATCAGCTAG
Protein Sequence
MATAARFAGSAAGGGGGGSNPPTPAPATTPPTPAATTTQLIVLPAGLHQTGTAIVNANGVPVLDVADLDHGADSSNESTATEPRGGEPHEADPLALGEESPHFITVTEATARSYASLTPVQPTVEAEAVASHPNYQVQYVDTELYASPANGGQAQMAYPVYSVGEGTIYAASQGQYYATHATNSGASTTVGYATTAGHYIVQQTVDADALIASTRNSPQTTNAETSYVATATVHATPSAVGEEVGSALSHATRVSPATVQWLLENYETAEGVSLPRSTLYAHYLRHCSENKLEPVNAASFGKLIRSVFLGLRTRRLGTRGNSKYHYYGIRVKPGSSLTTVEDAPGRTVATNAQGGKSAARGYKRGADALEQNMNAGVAPAHLTYLGDGNNAIPLFPDIEFAAPLPDECSYDDVDTLKSIYREHLEAFLDAILSLEFGTIESLWREFWRSQDNNNGEECEEEKYLSKAKLFAMCAQEPMQDFVRQVDLTFYQNLIQVLVPDVLKPIPASLTQSIRNFAKSMESWLTTAMAGAPPGMLAVKLSAAAAFSSSLRRYTSLNHLAQAARAVLHNSTQITQMLADLNRVDFQSVREQASWVCQCDNDIVARFEADFKLTLQQQNSLEQWASWLKNVVKSALKPYEGKQSFSKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLIEHQVAEATGIVPIAVMVEGIKQDHLSNNMSVYGSDAVCNGGSSMNVKLGCVSPSDPTKRMKIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00631247; iTF_01370737; iTF_01096348; iTF_00977061; iTF_01126091; iTF_01294700; iTF_01058861; iTF_01058111; iTF_00807383; iTF_01185916; iTF_00021952; iTF_00620321; iTF_00629547; iTF_00903840; iTF_00048400; iTF_00901971; iTF_00083639; iTF_00048997;
90% Identity
iTF_00631247;
80% Identity
-