Basic Information

Gene Symbol
-
Assembly
GCA_027574945.2
Location
JAODGD020033086.1:7065-7665[+]

Transcription Factor Domain

TF Family
zf-LITAF-like
Domain
zf-LITAF-like domain
PFAM
PF10601
TF Group
Zinc-Coordinating Group
Description
Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.49 3.1e+03 -1.1 0.0 59 66 7 14 5 29 0.69
2 3 0.43 2.7e+03 -0.9 1.2 32 47 52 61 41 71 0.57
3 3 3e-16 1.9e-12 47.6 2.8 5 69 92 156 89 157 0.95

Sequence Information

Coding Sequence
ATGAGTTCCTTCGGCACGTGTAAACTTTGCGGTGAGAGGATATCGTACAGCCCCGATCACGTTCAGAACTATGGGTTGCACCTTATCGAAAAACATCCGGAGATAGAGTTTGGCCATTTCGCACTGATCTACGAACCCACTGCAAAGTCATCATGTGTCCCATGCCCTTGCGGATGCGGGTGCGGGATGAAGGATTGTCTGACAAGATCCAAAGGACGACAACGATCgaataattataaaacaACCATTCAAAGTTGGAAGTGCGCTCAAAATCCTTTCCTCTGCCCGCGATGTAACAAAACGAATCCCCCGCTGATCAAGCGCCAGCGGCATAAATTGACAGGATCAAGCTGGATCGCGTGTATGCTGCTGGGATGCTGGCCATTCTGCTTCCTGCCGTTCATCATCAGCGGCAGCGATTTGTTCTACTTGTACTGCAAGGAATGCGGCTATTACATTGGCATGTTCGACCGTCGCGTTAGCGCCATTGACAAAGTACCTCCGTGCGCCGTCCCTGCTACCGGCGATGCACAGATTTGCGGTTGTCTCTAA
Protein Sequence
MSSFGTCKLCGERISYSPDHVQNYGLHLIEKHPEIEFGHFALIYEPTAKSSCVPCPCGCGCGMKDCLTRSKGRQRSNNYKTTIQSWKCAQNPFLCPRCNKTNPPLIKRQRHKLTGSSWIACMLLGCWPFCFLPFIISGSDLFYLYCKECGYYIGMFDRRVSAIDKVPPCAVPATGDAQICGCL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00632435;
90% Identity
iTF_00632435;
80% Identity
-