Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0077 59 4.2 0.0 18 44 122 148 116 156 0.81

2 7 0.014 1e+02 3.5 0.0 21 46 153 177 150 180 0.87

3 7 0.0018 14 6.2 0.0 21 48 181 207 178 212 0.86

4 7 0.033 2.5e+02 2.2 0.0 21 45 209 233 206 240 0.83

5 7 0.011 83 3.8 0.0 21 49 237 264 234 270 0.85

6 7 0.027 2e+02 2.5 0.0 23 48 267 291 264 296 0.83

7 7 0.0007 5.4 7.6 0.0 22 44 294 316 290 320 0.90

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0077	59	4.2	18	44	122	148	116	156	0.81
2	7	0.014	1e+02	3.5	21	46	153	177	150	180	0.87
3	7	0.0018	14	6.2	21	48	181	207	178	212	0.86
4	7	0.033	2.5e+02	2.2	21	45	209	233	206	240	0.83
5	7	0.011	83	3.8	21	49	237	264	234	270	0.85
6	7	0.027	2e+02	2.5	23	48	267	291	264	296	0.83
7	7	0.0007	5.4	7.6	22	44	294	316	290	320	0.90

Coding Sequence: ATGGACCCCAGCCAGCATCACTTTCCACATTTCCTAGACATCAAGCAAGAATTTTACTACTATGGCCCTGGTCCCTCCACGCACAACGGTATAAACACAATCCCACGTCCCTTCCCCAGCACCCAAGTGAACAGCTTACAGCCCCCCAACTTGCCTAACAGATTTGTGTACAGTATGAACCCTGAAGCTCCCTGTACCTCCAGTAGTCCTCAGTTCAACTCCCAGCGAGGGCATCGTAACAACGTCAAAACTCACACCACTAACTGCCCGCCACAGCTACCGAACTTCGACATCGAGACTGCGAACACTAGTAAGAAAATCAAGAAATGTTCAGAGTTAAAGATAAAGTTGGAGGCCAAGTCCAGTGAGCCACACGAGAAACCGTTCAAGTGTGCGGAGTGCGATAAACAGTTCAACCAGATGGCGAACCTTAAGAAGCACGAGATGGTCCACACGGGAGAGAAGCCTTACGAGTGCTCCGAGTGCGGGAAGTGCTTCACGCAGATGTCCAATCTTAAGAAACACGAGTTGATCCACAAGGGGGAGAAACCGTTCTCGTGTGGGGTGTGCGGGAAGGATTTCAGTCAGATGTCCAACCTTAAGAAACACGAGCTGATCCACTCTGAGGAGAAGCCGTATATATGTGTCGAGTGTGGCAAGGGCTTTAATCAGATGGCTAACTTGAAGAAACACGCACTCGTACATAAGGGGGAAAAACCTTACGATTGTGAAGATTGCGGGAAGTCGTTCTCTCAGatgtctaatttaaaaaaacatgagcTGATTCACCTTCAAGTGAAGCCGTTTCAATGTAATCAGTGTACGAAGTCGTTCAATCAGATGTCCAACCTTAAGAAACACGAGTTAATTCACAAGGGAGATAAGCCATATATCTGTACCTTATGTAGTGCTAATTTTAACCAACTGGCTAATCTGAAGAAACACATGTTAAGTCACTCCATTACTATGTAA
Protein Sequence: MDPSQHHFPHFLDIKQEFYYYGPGPSTHNGINTIPRPFPSTQVNSLQPPNLPNRFVYSMNPEAPCTSSSPQFNSQRGHRNNVKTHTTNCPPQLPNFDIETANTSKKIKKCSELKIKLEAKSSEPHEKPFKCAECDKQFNQMANLKKHEMVHTGEKPYECSECGKCFTQMSNLKKHELIHKGEKPFSCGVCGKDFSQMSNLKKHELIHSEEKPYICVECGKGFNQMANLKKHALVHKGEKPYDCEDCGKSFSQMSNLKKHELIHLQVKPFQCNQCTKSFNQMSNLKKHELIHKGDKPYICTLCSANFNQLANLKKHMLSHSITM

Sequence clustering based on sequence similarity using MMseqs2