Basic Information

Insect: Ecdyonurus torrentis
Gene Symbol: RXR
Assembly: GCA_949318235.1
Location: OX439131.1:8915026-8916258[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 8.6e-46 6.5e-42 144.7 0.0 197 407 200 406 157 408 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	8.6e-46	6.5e-42	144.7	0.0	197	407	200	406	157	408	0.86

Sequence Information

Coding Sequence: ATGGCTGGTGTTGGAGGCCCTCAGTCTCCTCTTGATATGAAACCAGATACTGCAAGTTTACTCAACGCTGCAGCATTTGGTCCTGGAGCTTTAGGTGGGCCAAATAGTCCTGGTCGTCCACAAGCATCCTTTACATTAGGACATGGAGCTGGAGATGGATCTGGCAGAAATAAAGCTGGAGGTTCAGGGTCCAGCAATGGCGAGGCTTCAAACAGTACTTATCCACCTAATCACCCGCTAAGTGGTTCAAAACATCTATGCTCAATTTGTGGGGATAGAGCAAGTGGTAAACACTACGGTGTGTATAGCTGTGAAGGATGTAAAGGATTTTTCAAGCGCACAGTGCGTAAAGATCTATCATATGCTTGCCGAGaagataaaaattgtattattgacAAAAGGCAAAGAAATCGATGCCAGTATTGCAGATACCAAAAATGTCTTGCGATGGGAATGAAGAGAGAAGCAGTGCAAGAGGAACGACAGAGGACTCGTGAGAAAGGGGAGGCAGAAGTGGAGAGTACCAGTAATGCTTACTCAGACATGCCTGTGGAGCGCATAATGGAAGCAGAGAGGAGAGTGGAGTGCAAGCTGGAGCCTCAGCCTGCACATGATTTACATGAACCAGACACTGCAGTGACCAACATCTGCCAAGCAACCAACAAACAGTTGTTACAACTTGTAGAGTGGGCGAAGCACATCCCGCACTTCTCAGCTCTTCCCATTGAGGACCAAGTACTTCTTTTACGAGCAGGTTGGAATGAGCTACTGATTGCTGCATTTTCACATCGCTCAATAGAAGTGAAAGATGGCATTGTTCTTGCAACAGGGTTAACTATACATCGAGATTCAGCTCATCAAGCTGGAGTGGGCACAATTTTTGACCGTGTCCTCACAGAGTTGGTTGCAAAAATGCGAGAAATGCGTATGGATAAGGCAGAACTGGGTTGTTTAAgggctattattttatttaatcctGATGTACGAGGGTTAAAGTCACAACAACAAGTTGAGATTCTCCGTGAGAAGGTTTATGCTGCTCTAGAGGATTATACTCGTTCTACAAGACCAGATGAACCTGGACGTTTTGCAAAGCTCCTGCTGCGTCTTCCATCCTTGCGCTCCATAGGACTCAAATGTTTGGAGCACTTATTTTTCTTCCGGCTGATTGGTGATGTACCTATTGATGAATTTCTCACTGAAATGTTAGAGTCTCAATCCCCTGACCCTTAG
Protein Sequence: MAGVGGPQSPLDMKPDTASLLNAAAFGPGALGGPNSPGRPQASFTLGHGAGDGSGRNKAGGSGSSNGEASNSTYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLSYACREDKNCIIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRTREKGEAEVESTSNAYSDMPVERIMEAERRVECKLEPQPAHDLHEPDTAVTNICQATNKQLLQLVEWAKHIPHFSALPIEDQVLLLRAGWNELLIAAFSHRSIEVKDGIVLATGLTIHRDSAHQAGVGTIFDRVLTELVAKMREMRMDKAELGCLRAIILFNPDVRGLKSQQQVEILREKVYAALEDYTRSTRPDEPGRFAKLLLRLPSLRSIGLKCLEHLFFFRLIGDVPIDEFLTEMLESQSPDP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01348099;
90% Identity: iTF_00650915;
80% Identity: iTF_00630637; iTF_00630551; iTF_00630555;