Basic Information

Insect: Dynastes tityus
Gene Symbol: Znf48
Assembly: GCA_029618875.2
Location: JAROYD020000003.1:2609764-2611386[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2.6e-07 3e-05 25.8 4.7 1 23 149 171 149 171 0.97

2 14 1.8e-08 2.1e-06 29.5 1.4 1 23 177 199 177 199 0.99

3 14 2.1e-05 0.0024 19.8 4.4 1 23 205 227 205 227 0.98

4 14 0.0002 0.024 16.7 2.4 1 23 233 255 233 255 0.98

5 14 3.6e-05 0.0042 19.1 4.4 1 23 261 283 261 283 0.98

6 14 1.1e-06 0.00013 23.9 1.5 1 23 289 311 289 311 0.98

7 14 2.2e-05 0.0026 19.7 1.6 1 23 317 339 317 339 0.98

8 14 1e-06 0.00012 23.9 0.8 1 23 345 367 345 367 0.98

9 14 7.3e-06 0.00085 21.3 4.2 1 23 373 395 373 395 0.99

10 14 7.4e-07 8.6e-05 24.4 2.9 1 23 401 423 401 423 0.99

11 14 9.6e-07 0.00011 24.0 0.7 1 23 429 451 429 451 0.98

12 14 9.5e-06 0.0011 20.9 4.0 1 23 457 479 457 479 0.98

13 14 0.015 1.8 10.8 2.3 1 23 485 507 485 507 0.98

14 14 2.6e-06 0.0003 22.7 1.4 1 23 513 535 513 535 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2.6e-07	3e-05	25.8	4.7	1	23	149	171	149	171	0.97
2	14	1.8e-08	2.1e-06	29.5	1.4	1	23	177	199	177	199	0.99
3	14	2.1e-05	0.0024	19.8	4.4	1	23	205	227	205	227	0.98
4	14	0.0002	0.024	16.7	2.4	1	23	233	255	233	255	0.98
5	14	3.6e-05	0.0042	19.1	4.4	1	23	261	283	261	283	0.98
6	14	1.1e-06	0.00013	23.9	1.5	1	23	289	311	289	311	0.98
7	14	2.2e-05	0.0026	19.7	1.6	1	23	317	339	317	339	0.98
8	14	1e-06	0.00012	23.9	0.8	1	23	345	367	345	367	0.98
9	14	7.3e-06	0.00085	21.3	4.2	1	23	373	395	373	395	0.99
10	14	7.4e-07	8.6e-05	24.4	2.9	1	23	401	423	401	423	0.99
11	14	9.6e-07	0.00011	24.0	0.7	1	23	429	451	429	451	0.98
12	14	9.5e-06	0.0011	20.9	4.0	1	23	457	479	457	479	0.98
13	14	0.015	1.8	10.8	2.3	1	23	485	507	485	507	0.98
14	14	2.6e-06	0.0003	22.7	1.4	1	23	513	535	513	535	0.98

Sequence Information

Coding Sequence: ATGGCCATAGAGTATGATGAATTGCATGAACATTACGATAATAACTGCGAAGAATACAATAGTGCCGCacatattaaattagaagattgtATAGTTCAAACGGGGGACtttcttgattcaaaagcaggaatatctttgataagcGACGACATCTTAGCACAAGAGGTCTCATTGGTAAATATTAAAGATGAAAATTTCGATGAGCAATTAAGCAAGGATATCATTAGTACCGAGGACTGTGAAAAATTTAATAGTGATGTagatattaaattagaagattctATAGTTGAAACAGGAGATTATCTTGATTCAAAAGTAGGAATATCGTTGATAAGTGATCACAGCGTAGCACAAGGTGAAAATTCGAACGACTATTACAATAAAAGCTTTAAGCACAAACAGCTATTTCATCATGTTAGGAGCATGCATTTGCTCGGGAAGATTCACATGTGTAGCTATTGCGGGCGGACGTTTCGTCGCAAGACCGATCTGACGAAACATGTTAgaacacacaccggtgaaaagccttttacttgcgaaatttgtaaaaaatcgttTTCTGAGAAGAGTAACCTGACGGCTCATATTAGAAGACACACGGATGAAaaaccttttacttgcgagatttgtaagaAGTCATTTTGTGACAAGAATAGATTGAAGAAACATATTACAATACACACGGGTGAAAAGCCTTtcacttgcgagatttgtaagaACTCATTTTGTGAGAAAGGTGGACTGACAAAACATGTTAGAAATCACAACAATGTAaaaccttttacttgcgagatttgtaagaAATCATTTTGCGAGAAGGGTAGACTGAAGAAACATATTACAACACACAcgggtgaaaagccttttacttgcgagatttgtaagaAGTCATTTAGTGAGAAGGATGGACTGAAGAAGCATATTACAAGACACGCACGTGAAAAGCCTTTTAGTTGCGAAGCTTGTAAGAAGTCATTTCGTGAGAAGTATGTACTGATGAGACATATTAGAACACACTCCGGTGAAaaaccttttacttgcgaggtttgtaaaaagtcatttgcTAGGAAGAATGGACTGACGATTCACATGATAAAACACACCCGCGAacagccttttacttgcgagatttgtaaaaggTCATTTTGTGAGAAGGGTAGACTGAGGAGACATATTAgaacacacaccggtgaaaagccttttacttgcgagatttgtaagaAATCATTTTGCGGGAAGGATGGACTGAAGAATCATATTAGAACACACACcggtaaaaaaatgtttacttgcgAGGTCTGTAAAAAGTCGTTTACTGGTAAGAGTGGACTCACGATTCATATGATaaaacacaccggtgaaaagccttttacttgcgaaatttgcaaaaagtcatttTTTCGGAAGAGTGGTCTAAAAACTCACACGAAATATCACACCGGTGAAAAACGTTTTACTTGTGAAGTTtgtaaaatgcaatttttctGCTCTGCATATCTACAAAGACATATGGCAGTGCATATGGGGGATTGCCCTTATTCTTGTGAGTTGTGTTCCGCCAAATTTAGGAATTCGTACAGTCTGACACGGCATATGAGGTGgcatattaaaaaggaaatctAA
Protein Sequence: MAIEYDELHEHYDNNCEEYNSAAHIKLEDCIVQTGDFLDSKAGISLISDDILAQEVSLVNIKDENFDEQLSKDIISTEDCEKFNSDVDIKLEDSIVETGDYLDSKVGISLISDHSVAQGENSNDYYNKSFKHKQLFHHVRSMHLLGKIHMCSYCGRTFRRKTDLTKHVRTHTGEKPFTCEICKKSFSEKSNLTAHIRRHTDEKPFTCEICKKSFCDKNRLKKHITIHTGEKPFTCEICKNSFCEKGGLTKHVRNHNNVKPFTCEICKKSFCEKGRLKKHITTHTGEKPFTCEICKKSFSEKDGLKKHITRHAREKPFSCEACKKSFREKYVLMRHIRTHSGEKPFTCEVCKKSFARKNGLTIHMIKHTREQPFTCEICKRSFCEKGRLRRHIRTHTGEKPFTCEICKKSFCGKDGLKNHIRTHTGKKMFTCEVCKKSFTGKSGLTIHMIKHTGEKPFTCEICKKSFFRKSGLKTHTKYHTGEKRFTCEVCKMQFFCSAYLQRHMAVHMGDCPYSCELCSAKFRNSYSLTRHMRWHIKKEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00627885;
90% Identity: iTF_00627885;
80% Identity: iTF_00627885;