Basic Information

Gene Symbol
-
Assembly
GCA_029618875.2
Location
JAROYD020000003.1:2641527-2643401[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 1.1e-06 0.00012 23.9 6.2 1 23 149 171 149 171 0.97
2 17 3.1e-08 3.6e-06 28.7 1.1 1 23 177 199 177 199 0.99
3 17 0.00029 0.034 16.2 3.5 1 23 205 227 205 227 0.98
4 17 3.3e-05 0.0038 19.2 4.2 1 23 233 255 233 255 0.98
5 17 4.3e-06 0.0005 22.0 5.0 1 23 261 283 261 283 0.99
6 17 8.4e-08 9.8e-06 27.4 1.3 1 23 289 311 289 311 0.99
7 17 4.1e-06 0.00048 22.0 2.8 1 23 317 339 317 339 0.98
8 17 1.2e-05 0.0014 20.6 0.3 1 23 345 367 345 367 0.98
9 17 2.7e-05 0.0032 19.5 5.4 1 23 373 395 373 395 0.99
10 17 2.8e-07 3.2e-05 25.7 1.7 1 23 401 423 401 423 0.99
11 17 0.00019 0.023 16.8 5.5 1 23 429 451 429 451 0.99
12 17 3e-06 0.00036 22.4 1.4 1 23 457 479 457 479 0.98
13 17 0.043 5 9.4 0.8 7 23 491 507 485 507 0.87
14 17 1.6e-05 0.0019 20.1 1.8 1 23 513 535 513 535 0.98
15 17 2.1e-06 0.00025 22.9 3.1 1 23 541 563 541 563 0.98
16 17 1 1.2e+02 5.1 2.8 1 23 569 591 569 591 0.97
17 17 6.5e-05 0.0076 18.3 1.5 1 23 597 619 597 619 0.98

Sequence Information

Coding Sequence
ATGGCCACAGAGTATGATGAATTGCATGAACATTACGACAATAACTGCGAAGAATATAATAGTGCCGCagatattaaattagaagattgtATAGTTCAAACggaagattttcttgattcaaaagcaggaatatctttgataagcGACGACATCTTACCACAAGGTGTCTCATTGGGAAATGTTAAAGATGAAAATTTGTATGAGCAATTAAGCAAGGATATCGTTAGTACTGAGAACtgtgaaaaatataattgtaatgcagatattaaattagaagattttgTAGTTCAAACaggagattttcttgattcaaaaggAGGAATATCGTTGATAAGTGATCACAGCGTAGCACAAGGTGAAAATTCGAATGACCATTACAATAACAGCTTTAAACACAAACAACTACATCATCATATTAGGAGCGTGCATTTGCACAAGAAAAATCACATGTGTAGATATTGCGGACGGACGTTTTGTCGCAAGGCTGATCTGACGAAACATATTAgaacacacaccggtgaaaagccttttacttgcgaaatttgtaaaaaatcattttctgagAAGAGTAACCTGATGGCTCATATTAGAAGACACAcgggtgaaaagccttttacttgcgagatttgtaacaAGTCATTTTGTGAGACGAATAGACTGAAGAAACATATTACAGTACACAcgggtgaaaagccttttacttgcgagactTGTAAGAAGTCATTTTGTGAGAAGGGTGGACTGACGAAACATGTTAGGAAACACACcagtgaaaagccttttacttgcgagatttgtaagaAATCATTTTGTGAGAAGGATAGACTGAAGAAACATATTAGAACACACACTgatgaaaagccttttacttgtgagATTTGTAACAAGTCATTTAGTGAGAAGGATGGACTGAAGAAACATATTAGAAGGCACGCCTGTGATAAGCCTTTTAGTTGCGAAACTTGTAAGAAGTCATTTCGTGAGAAGTATGTACTGACGAGACATATTAGAACGCACTCCGATGAAaaaccttttacttgcgaggttTGTAAAAAGTCGTTTGCTGGGAAGAATGGATTGACGATTCATATGATAAAACACACcggtgaaaggccttttacttgcgagacttgtaaaaagtcattttgtgAGAAGGGTAGACTGAGGAAACATATTAgaacacacaccggtgaaaagccttttacttgcgagatttgtaagaAGTCATTTAGTGAGAAGGAGGGACTGAAGAAACATATTAGaaaacacaccggtgaaaagccttttacttgcaaagtttgtaaaaagtcgtTTCTCATGAAGCATACACTGACGAGACATATTAGaacacacactggtgaaaagccttttacttgtgagATTTGTAAAAAGCCGTATGCTGATAAGCATGGACTGACGAGACATATGATAAAACACACTGGTGACAAatcttttacttgcgagatctataataaatcatttagtgaCAAGTGTGTATTGaagaaacatattaaaatacacactgttgaaaagccttttacttgcgaagtttgtaaaaagtcgtTTACTGCGAAGCATGTACTGATCAAACATATTAGaatacacaccggtgaaaaaccttttacttgcgaaatttgcaaaaagtcatttTTTAGGAAGAGTGGACTAAAAACTCACATTAAATATCACACCGATGAAAAACGTTTTActtgtaaagtttgtaaaatgctATTTTTCTGCTCTGCATATGTAAAAAGACATATGGCAGTGCATATGGGGGATTGCCGTTATTCTTGTGAGTTGTGTTCCGCTAAATTTAGGAATTCATACAGTCTATCACGGCATGTGAGGCAgcatattaaaaaggaaatctAA
Protein Sequence
MATEYDELHEHYDNNCEEYNSAADIKLEDCIVQTEDFLDSKAGISLISDDILPQGVSLGNVKDENLYEQLSKDIVSTENCEKYNCNADIKLEDFVVQTGDFLDSKGGISLISDHSVAQGENSNDHYNNSFKHKQLHHHIRSVHLHKKNHMCRYCGRTFCRKADLTKHIRTHTGEKPFTCEICKKSFSEKSNLMAHIRRHTGEKPFTCEICNKSFCETNRLKKHITVHTGEKPFTCETCKKSFCEKGGLTKHVRKHTSEKPFTCEICKKSFCEKDRLKKHIRTHTDEKPFTCEICNKSFSEKDGLKKHIRRHACDKPFSCETCKKSFREKYVLTRHIRTHSDEKPFTCEVCKKSFAGKNGLTIHMIKHTGERPFTCETCKKSFCEKGRLRKHIRTHTGEKPFTCEICKKSFSEKEGLKKHIRKHTGEKPFTCKVCKKSFLMKHTLTRHIRTHTGEKPFTCEICKKPYADKHGLTRHMIKHTGDKSFTCEIYNKSFSDKCVLKKHIKIHTVEKPFTCEVCKKSFTAKHVLIKHIRIHTGEKPFTCEICKKSFFRKSGLKTHIKYHTDEKRFTCKVCKMLFFCSAYVKRHMAVHMGDCRYSCELCSAKFRNSYSLSRHVRQHIKKEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00627883;
90% Identity
iTF_00627883;
80% Identity
iTF_00627883;