Dtit051306.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Dynastes tityus
Gene Symbol
ZNF217
Assembly
GCA_029618875.2
Location
JAROYD020000021.1:1285981-1304228[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 30 1.3 1.6e+02 4.7 1.9 2 23 125 145 124 145 0.94
2 30 0.00016 0.019 17.0 0.2 1 23 147 169 147 169 0.99
3 30 0.03 3.5 9.9 0.2 1 23 174 196 174 196 0.97
4 30 0.67 78 5.6 0.3 1 23 200 223 200 223 0.94
5 30 0.008 0.93 11.7 0.1 2 23 230 251 230 251 0.96
6 30 0.0015 0.18 13.9 1.8 1 23 257 280 257 280 0.95
7 30 0.00049 0.057 15.5 1.2 1 20 291 310 291 311 0.96
8 30 1.4e-05 0.0017 20.3 0.0 2 23 323 344 322 344 0.97
9 30 0.0001 0.012 17.7 1.6 1 23 350 372 350 372 0.98
10 30 0.00084 0.098 14.8 1.8 2 23 416 438 415 438 0.94
11 30 4.6 5.4e+02 3.0 2.9 1 23 458 480 458 480 0.98
12 30 0.057 6.7 9.0 2.9 1 23 483 505 483 505 0.97
13 30 0.0012 0.14 14.3 0.4 1 23 510 533 510 533 0.98
14 30 9.9e-06 0.0012 20.8 0.1 1 23 539 561 539 561 0.97
15 30 0.025 2.9 10.1 0.9 1 23 567 590 567 590 0.94
16 30 0.00028 0.033 16.3 0.3 2 23 602 623 601 623 0.97
17 30 8.2e-06 0.00096 21.1 1.6 3 23 635 655 633 655 0.96
18 30 1.5e-05 0.0017 20.3 1.4 1 23 661 683 661 683 0.99
19 30 4.8e-07 5.6e-05 25.0 1.0 1 23 689 711 689 711 0.98
20 30 7.8 9.1e+02 2.3 0.0 3 23 808 828 806 828 0.89
21 30 0.0065 0.76 12.0 0.7 1 21 847 867 847 870 0.89
22 30 0.003 0.36 13.0 1.0 1 23 875 898 875 898 0.94
23 30 0.013 1.5 11.0 0.6 1 23 906 928 906 928 0.98
24 30 0.00018 0.021 16.9 0.1 2 23 935 956 934 956 0.96
25 30 0.016 1.9 10.7 0.9 1 23 962 985 962 985 0.95
26 30 5.3e-05 0.0062 18.5 3.6 2 23 997 1018 997 1018 0.97
27 30 0.00068 0.08 15.0 1.4 3 23 1026 1046 1025 1046 0.98
28 30 7.6e-05 0.0088 18.1 3.6 1 23 1052 1074 1052 1074 0.98
29 30 1.8e-05 0.002 20.1 1.9 1 23 1080 1102 1080 1102 0.98
30 30 0.0021 0.25 13.5 0.0 1 22 1108 1129 1108 1129 0.97

Sequence Information

Coding Sequence
ATGAGTGACTTAAGACCTATATCCATTCTTCCTGTGCTGTTGAAGGTCTTGGAGAATATTGTTGATATACAGATATGCTGTTGCTtggataaaaacaatatattacCGAACGAGCAGCCAGGGTTTAGGTTAACTTATAAAAATTTCGGACAATTGGCGGTCTTCGTAATTGAAGATGAGCCATCAGACCACGAAGAAGATGCTAACCTAAACCCCTCGCAATCGGAGGATTTCAACCTGTTAGAGCGGGACGATATCGTTATCATCCAAAACGACATGTTCAACGATGAAGGTCGTACCAATAGCGAAGAGGAGAATCAGGTTGAGCAACCGAAATTGTTGAGAAAGAATGCCTCTAGGGAACAAAGTATCGTTTGCTCCGAATGTGGGAAATTGGTTAGGTACAAACATTATGACAAGCATACCAAGTCTCATACGTATAAGTGTCAACAGTGTCCCGAAACTTTTGGTACTCAAAGGGCATACGAAGCTCATGTAAAGGTTCATAGTAATAATTCTTTTACGTGTTCCATTTGTAATATAGATTTTGGAAGCGCTGAAGCGTTCTCTATCCATAACCAGAAGCATTCCGGCTTCTTCAAATGCCCTTTATGCCCGTTTGAGACCGGTACAAAGACTTCCATGAAACCTCACATCAAGTTAATGCACATGAAAGAGTACAAAAGGGTATGCGAGATCTGTGGGAAAGGTTTTCTAAACAATGCTACATATACCGACCATATGACGCTCCATTTAGGcgagaaaaaatataaatgtgaATACTGTGATAAGAAATTTGTCCTTAATAGATACTTGGATATCCATAAAAAATTGAACCATAAAGACATCATAAACGGTGTTGAAGAATACTACTCTTGTCACGTTTGTAATCGGGCCTTCAAGTTCGAGAAAAGCCTCATCAGACACCTTAGTTGTATCCACGACATTGGAGCAAGCAAAAGGGTACCTTGTCCTATTTGCAACAAGATTCTCGCTAACAATTATGGCCTGAAGATTCATATGAGGACTCATAGTGGGGAGAAGCCTTACAGTTGCGAATTATGTGACGCAAAATTTGCTAGGACGAAATATCTTCAAAAGCATATGACCAAacatgtaaatatgtATGAACTAAAGTACTCGGATATCATATCAAAGGTTAAGGTAGAGCTAAACGATAGGATACCGTCTAAAGGCAGGCTGTACAAGAACAAAACGAAATCCAATTGTCCCGACAAGAAGTGGCCATGTAAGAAGTGCAGCGAACGCTTCTCGACAGTCCGCCAATTGAGAAAGCACCGGAAGGAGACACATCGAAGGAACGTTAATATTAACCGATATAATTTCTCCTACAACCAACCAGAGGGCATCTATTCCTGTAATAATTGCGCTAAGAAGTCGAGATGTCAAAAAGAAATGGAGGATCATGTCCAAACTCATGAGCCGTACGTGTGTTCGATTTGCGATTGCGAATTCTATTCCCTGTACAAATTCTCTGTGCATAATCAAAGCCACGATTCCACCTATTTTAAATGCCCCCTATGTGATTACCAAACGGCTAGAAAGACAGCGATTTTACGACATATAAACACCAACcacttaaataaatatatttacaattgcaataTCTGCGGTAAAGGCTTTGAAGACGCCGCGAATTTTAGAGACCATCAAAATGGCCACGCTGGAGCTAAGGCTTTTTCATGCATAGTTTGCCAGAAAGAATTCCCGTTCAATAGATACCTTCTAGCGCATCAAAAGAGGAACCACATGGTTACAATTGATGGGGTCCTCTTACCAAACCAATGCGGCGTTTGCAAGAGAATCCTATCGAAACCatcaaatttagaaaagcatatGATACAGCATGACGCGGCTTTTCTCCAAGCCACGCATCACCTTTGCGACATCTGTGGGAAAGGCTTCGCTAGGAAAGATAAGCTTCGTCTTCACTATAGGATGCATACTGGGATAAAACCATATAAATGCAATTATTGCTCGAAATCTTTTGCGAAAAGGGAGTACTTGATAATGCATGAACGCATCCATAGTGGCGAAAAACCTTTCGTCTGCCAATACTGTGGGAAGGCCTTTAATCAGAGGACCTCCTTAAAGACGCATATCCGTGGTCACACCGGCGAGAGACCGTGCCATAGACCGTTGAAGTTAACTCTAAAGAAAACCTCAAAAGATTCGAAAACTGTAAATTGGAACAAAAAGCTACCCGAAATCGATATTATACCCGTCGAAAAGGTGAAATTAGAACCCAGCTATAAGCCAAATGAAGATTTTGATGAGTTAGAAATCACCAAGAAACCTCTACCAATCGGCTATGTGAATCCGttcaattacttaaatttaaaagctAAAAATCTCCCGCGAAAATCGAAACAACCGGAATATACCAACCGAAAGTGGACGTGCATCATTTGCGGTGACGTGGCATCTAGTAAAGAAACCTTAATAGATCACTATGAGATCCACAGGATCAACAAGGAGACTAAGGTTATGGAGACCTTCGCTAATGATACTGAGTATTTTAATTGCGCCATCTGTGGTCAAGAGTTTACATCGCTCAAGACCTACGAGAGGCATTTCGATGCGAAGCATGGTGAGAGGAATTACACTTGCTTTGTCTGTCAGAAAGTCTACAAAGATGCTTTCCAATTGGCAATTCACAATTATACTTTCCACCCTGAGGATTACGATTACGCCTATCAATGTGTCTTGTGTGATTTTAAGACGGCCTTCAGGGGTAATTTGAAAGACCATCTTCTCCAACACGAAGCTTCTTGCAAGCTCAAATGCGAGATCTGCGGGAAAGGCTTTGAAAACGAGGCCAATTACGAGGAACACAAAAGTATGCATGGCAGCACGGCTTCGTTTTCTTGCGATGTTTGTGGTGACACTTTCCCATACACCCAGCACCTTATAAATCACAAAAAAGAGGTCCACCCAGAGATTTTCGGGGATAATCTCAACCAAAATGAGTGTCAcatttgcaataaaaagttTGCCCATAAGAAGAGTCTAATTCTCCACATCCGAGGTCATACAGGTGAGGATTCTGTTCTCTGTGATATGTGCGGTAAACGCTTAACTAGCGGAGAACACCTCAAGCAACATCTGAGGATCCATACAGGGTTTAAACCTCATAAATGCTCGGTTTGTGGTAAAGGATTTGCTAAGAAATGCAACCTGACCTTGCATGAGAGAGTTCATAGTGGGGAGAAGCCCTATAAGTGCAGGGTTTGTTCAAAATCCTTCTCCCAACGTTCTACCTTGGTAATACATGAAAGATATCATAGTGGGGAACGCCCATACGTTTGTACCCTTTGCAACAAAGGCTTTGTAGCTAAAGGTTTGTTAAGTGTTCATATTAAAACATGCAGTGCAATCCCTGAAGATTATCTAGTTGCTTAA
Protein Sequence
MSDLRPISILPVLLKVLENIVDIQICCCLDKNNILPNEQPGFRLTYKNFGQLAVFVIEDEPSDHEEDANLNPSQSEDFNLLERDDIVIIQNDMFNDEGRTNSEEENQVEQPKLLRKNASREQSIVCSECGKLVRYKHYDKHTKSHTYKCQQCPETFGTQRAYEAHVKVHSNNSFTCSICNIDFGSAEAFSIHNQKHSGFFKCPLCPFETGTKTSMKPHIKLMHMKEYKRVCEICGKGFLNNATYTDHMTLHLGEKKYKCEYCDKKFVLNRYLDIHKKLNHKDIINGVEEYYSCHVCNRAFKFEKSLIRHLSCIHDIGASKRVPCPICNKILANNYGLKIHMRTHSGEKPYSCELCDAKFARTKYLQKHMTKHVNMYELKYSDIISKVKVELNDRIPSKGRLYKNKTKSNCPDKKWPCKKCSERFSTVRQLRKHRKETHRRNVNINRYNFSYNQPEGIYSCNNCAKKSRCQKEMEDHVQTHEPYVCSICDCEFYSLYKFSVHNQSHDSTYFKCPLCDYQTARKTAILRHINTNHLNKYIYNCNICGKGFEDAANFRDHQNGHAGAKAFSCIVCQKEFPFNRYLLAHQKRNHMVTIDGVLLPNQCGVCKRILSKPSNLEKHMIQHDAAFLQATHHLCDICGKGFARKDKLRLHYRMHTGIKPYKCNYCSKSFAKREYLIMHERIHSGEKPFVCQYCGKAFNQRTSLKTHIRGHTGERPCHRPLKLTLKKTSKDSKTVNWNKKLPEIDIIPVEKVKLEPSYKPNEDFDELEITKKPLPIGYVNPFNYLNLKAKNLPRKSKQPEYTNRKWTCIICGDVASSKETLIDHYEIHRINKETKVMETFANDTEYFNCAICGQEFTSLKTYERHFDAKHGERNYTCFVCQKVYKDAFQLAIHNYTFHPEDYDYAYQCVLCDFKTAFRGNLKDHLLQHEASCKLKCEICGKGFENEANYEEHKSMHGSTASFSCDVCGDTFPYTQHLINHKKEVHPEIFGDNLNQNECHICNKKFAHKKSLILHIRGHTGEDSVLCDMCGKRLTSGEHLKQHLRIHTGFKPHKCSVCGKGFAKKCNLTLHERVHSGEKPYKCRVCSKSFSQRSTLVIHERYHSGERPYVCTLCNKGFVAKGLLSVHIKTCSAIPEDYLVA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01121016;
90% Identity
-
80% Identity
-