Basic Information

Insect: Drosophila yooni
Gene Symbol: RREB1
Assembly: GCA_035043035.1
Location: JAWNNG010000885.1:23094-29952[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.037 2.4 8.8 0.8 1 21 273 293 273 295 0.93

2 12 0.00034 0.022 15.2 0.2 1 23 305 327 305 327 0.98

3 12 0.00025 0.017 15.6 7.2 1 23 333 355 333 355 0.98

4 12 0.9 59 4.4 1.5 2 20 586 604 586 606 0.93

5 12 0.017 1.1 9.8 0.2 1 23 750 772 750 772 0.97

6 12 7.1e-06 0.00046 20.5 1.2 1 23 782 804 782 804 0.99

7 12 0.003 0.2 12.2 2.0 1 23 1078 1101 1078 1101 0.95

8 12 8.8e-05 0.0058 17.0 0.3 2 23 1468 1489 1467 1489 0.97

9 12 0.15 9.7 6.9 6.3 1 23 1495 1518 1495 1518 0.97

10 12 9.6 6.3e+02 1.2 3.4 1 23 1638 1661 1638 1661 0.78

11 12 0.0086 0.56 10.8 0.5 3 23 1721 1741 1719 1741 0.96

12 12 0.0014 0.089 13.3 4.8 1 23 1747 1769 1747 1769 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.037	2.4	8.8	0.8	1	21	273	293	273	295	0.93
2	12	0.00034	0.022	15.2	0.2	1	23	305	327	305	327	0.98
3	12	0.00025	0.017	15.6	7.2	1	23	333	355	333	355	0.98
4	12	0.9	59	4.4	1.5	2	20	586	604	586	606	0.93
5	12	0.017	1.1	9.8	0.2	1	23	750	772	750	772	0.97
6	12	7.1e-06	0.00046	20.5	1.2	1	23	782	804	782	804	0.99
7	12	0.003	0.2	12.2	2.0	1	23	1078	1101	1078	1101	0.95
8	12	8.8e-05	0.0058	17.0	0.3	2	23	1468	1489	1467	1489	0.97
9	12	0.15	9.7	6.9	6.3	1	23	1495	1518	1495	1518	0.97
10	12	9.6	6.3e+02	1.2	3.4	1	23	1638	1661	1638	1661	0.78
11	12	0.0086	0.56	10.8	0.5	3	23	1721	1741	1719	1741	0.96
12	12	0.0014	0.089	13.3	4.8	1	23	1747	1769	1747	1769	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcaacagcaacaatcgcacacagcagcagcaactgcagcagcaacacaagaGGATGCTCGGGATTTGGGCTTAATGGAGACGCGACAACGTCGCGATTCGAGTACCTCAGAATCCTCGCTGGAGCATTTGGATTTAAGTCGCACGCCCAAAaaattgagcagcagcagtggcgcACCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGAAAACTgcgacagcaacaccagcagcagcagcagcaacagttgccgctcTCCGatgaggagcaacagcagcaacagcagcagcagctgttggatTCGTCAGCGCAGCGACCGCGTCACAAGCAGCGACGtagcgctgttgctgccgctacCAGCGCCAGCATCGTTGTTGACTACAGCGCGAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGTGATTTATCCGAGTCTGGCTTTGTTGATGGCAGCGCCGTCAGTGGCTATCTgcttagcaacaacaacaataacaacaacaataacaacaacaacaataacaacaacaataacaacaacaataacaacaacaataacaatatcaacaacaatatcagtagtagtagcagcagcagcgcagtcgctcagtcagcagcagcagcagcgtcggcaGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCTGGTGATGAGCACATGAAATATCTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCGCTGGACCGGCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAATATGCACCGACACATGCGCACCCATAAGCAACATCAGgcttcgcagcagcagcagcagcagccctcgcaacagcagcaatcaacccaacagcagcaacagccacaatcgcagtcgcagcaacagcaacagcggcgccAGCAACATGCGGGCGGAGCAGGCGCAACTGGCTCGGGATCGGGATCGGGTTCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGTTCGACGGATGTGTCCAGTGAGCTGAAcagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaatagccacaaaacgaacaacaataacaacaataataataataataataataacaatgaggATGAGCTCGAGCTGGAGGATGAGCAGCTAGTATtgagcagcaaacagcgacGCCTCAAGGCAAccctaaacaacaacaatataattaGGGATGAGGAGCAGGAGAATCGTGTGGATGATGATTCAGATGTGGACAGCGTTGAAAGTGTGGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGTTGCTCGCCTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATTACATTCACCGCCCTTGCTGCAGAGCTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGGGGACATACCGGCCAAGTGTCGCGAGTGTGAGGTGATCTATGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGCGGATTGCCGCCGCTGCTTGGTGCGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAAttggaggagcagcagcagcagcacgaggAGGACCACgaacagcagcacaagcaggaGGAACAGGAGCACGCCGAGCAGCGCGAATGTGAAGATTTCTTTCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTTCTTCCCTCCCCGATCAAACATGAGCCGGCGGACCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACATCCAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATACAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTCCGCCGAATGAAACTGCGCGGTGAGTTCCCCTGTAAGCTGTGCAGCGCGGTCTTTCCCAATTTGCGGGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCGGGTCCATTCCGTTGCAACATGTGTCCCTATTCCGTCTGCGACAAGGCGGCGCTCGTCCGGCACATGCGCACCCACAACGGTGATCGGCCATACGAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCCCGGACCGATGCCGATATGCTAACCGAGCTGAGCGGCTATCGCTGTCCTACACCCACTGAGCAAAGCTCCTCGGCTAGCTCCTCGTCACAGCTGAAGCATATGTTGCTGGCGGAGCCGACGCCGGCCGTAAaggtaacagcaacagtggcagcaacaacatcgctGCCGCAACAACCGCTCAAGATTCAAGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTCAGCATGGATGCGCTCGACCTGAGCAAGAAGCCCGCACAGCTGCTGGCCGAGCAAAGGGAGCAAAGGGAGCAGCTCGAAAGACAcgaattgctgctgcagcagcaacaccaacaacagcagcaacaacaccagcaacaacaccagcaacaacagcagcagcaacaaatgttcGGGGCTGGCGATGCAGCTGCTCAGCAtatgcaacagctgttgcGCAGCTTTATGCTCCAGCAGGCACCCGGTTTTCCCTTCTTTGGCTTTCTCacgccaccgccaccagcaacggcagcagcagcaacagcagcagacaagtcaatgccaacaaatccagcagcagcagccggggcaacagcagcaacaattgctgcaatGCCACTGTCGCTGCCCGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcgccGCTATCGCACCGAGCGTCCCTTTGCCTGCGAGCACTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCAtgtgaagcagcagcatccacagtTCTATGCGCTGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCGTCCTCGAGTGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcagctgccgcagcaatGAATAAtctcagccagcagcaacagttgcagcagcaacagttgcagcattcacattcacatcaCGTCCATGCACCAATTTCGGAGCAGGTGAAATATGCGATTTTGGCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGCTCCAGCAGTGTTGTCGCCAATCCGCTGCTGAATTttagctacaacaacaacggcaacagcaacaagcagcatcagcaacaacagttgggCAACAACACTGGCAACTCTTTGGATGTGGAGGGAgaggacgatgaggatgaggaggaggagcaggaatTTGATGTCgatgaggaggagcaggaggatgAAGAGATGGACTTGGACGatgagcatcagcagcagccgcacgaggaagatgacgatgacgatgatgatgatgctgatgctgccgcagcagcagcagcagcaacagaggcatcgcaacaacaattgcagccaaCAAAGGACAAACTTCAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCGAGAAGCAGCCGCATACTCAAGCGGAGTCCCTGGGCGGCAATAAGCCGGcgacgccaacaacaatgaaaacaatgatTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTTAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAATGCCACCAGCAATCAGGTGTCCTTCAACAGCTATTTCCGTCCCAGCGACGTTGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaacGATACCAAAAAGAAATCCGCCTACAGCCTCGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACACACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTCTTCACCACAAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCTGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATTCCCGTGCCCAAGTCGGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAGGCCGAACAGGCCGAGCGGGAGCAGCGCGAGCGTCAAAAGGAGCGCGAACgtgaactggaactggaacgggaacgggagcgGGAACAGCAACATTTGATACAACAGTATCGCCAACAAAtggccgctgctgcagcggctgctgctgccgttgctgctgtcgctgcaccAGCGCATCCAACACCACCACAGCCAGCCCAATCGCCACCGGGCCTGGAAGCGAGCAGTGATCTGCCCTATAAATGCCATCTTTGCGAATTCTCGTTTGGCGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCACGCTCACGACTTCGCACTGCTCCTGGCCAAGGGGGCCATCGAAACGGATGCACAAgtgcagcatcaacagcagcaacagttgccaatgGCCGGTGGTGCTCCACATTCGGATGATGAGGCTGCTGCCGTCGGCACCAGATCGGGCAAATATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATTTGCGCCGACATATGCGCACTCATTCCGGTGAGCGGCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAACTCGATCATCAATCCGATTGCTCCGATGATGAGCAACTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacacttgccagaacaacaacaacaacaataacaacaacaatagcaatagtAACAGCAAGCAGGTGCTGCGCGAGCTGCTCGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCAAAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcggcggcagcagcagctgtagccAGTGGCGATCTAATTGGTAATCTGTTAGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCGGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTAA
Protein Sequence: MLATQQQQQQQSHTAAATAAATQEDARDLGLMETRQRRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQQHQQQQQQQLPLSDEEQQQQQQQQLLDSSAQRPRHKQRRSAVAAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSAVSGYLLSNNNNNNNNNNNNNNNNNNNNNNNNNNNINNNISSSSSSSAVAQSAAAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQPSQQQQSTQQQQQPQSQSQQQQQRRQQHAGGAGATGSGSGSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNSHKTNNNNNNNNNNNNNNEDELELEDEQLVLSSKQRRLKATLNNNNIIRDEEQENRVDDDSDVDSVESVAQVITSTPDVATLLASGGTSPTHSHSELHSPPLLQSCPACNSGEFESVPALCAHLDAEHGDIPAKCRECEVIYATHRQLQAHSCRGLPPLLGASSSPLHKQEESELEEQQQQHEEDHEQQHKQEEQEHAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYSVCDKAALVRHMRTHNGDRPYETSREDVKRAIVYHPAEDASCEENKSRTDADMLTELSGYRCPTPTEQSSSASSSSQLKHMLLAEPTPAVKVTATVAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQHQQQQQQHQQQHQQQQQQQQMFGAGDAAAQHMQQLLRSFMLQQAPGFPFFGFLTPPPPATAAAATAADKSMPTNPAAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYALRQRHRSGHHVMRERAASSSAVQAAAAAQAAAAAAAAMNNLSQQQQLQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLNFSYNNNGNSNKQHQQQQLGNNTGNSLDVEGEDDEDEEEEQEFDVDEEEQEDEEMDLDDEHQQQPHEEDDDDDDDDADAAAAAAAATEASQQQLQPTKDKLQSKPIEAAKKVAETILEQAIKEREEKAEKQPHTQAESLGGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREQQHLIQQYRQQMAAAAAAAAAVAAVAAPAHPTPPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHDFALLLAKGAIETDAQVQHQQQQQLPMAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNTCQNNNNNNNNNNSNSNSKQVLRELLGKANEWRVSRLGEQKENIAEATTTPSAATAAAAATAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00525357;
80% Identity: -