Basic Information

Insect: Drosophila yooni
Gene Symbol: Hr39
Assembly: GCA_035043035.1
Location: JAWNNG010000819.1:431745-434805[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.3 1.2e+04 -4.7 17.2 32 206 29 218 20 222 0.51

2 3 2 1.8e+04 -10.4 26.6 47 148 205 331 183 370 0.34

3 3 4.1e-100 3.6e-96 323.1 12.0 1 408 503 894 503 894 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.3	1.2e+04	-4.7	17.2	32	206	29	218	20	222	0.51
2	3	2	1.8e+04	-10.4	26.6	47	148	205	331	183	370	0.34
3	3	4.1e-100	3.6e-96	323.1	12.0	1	408	503	894	503	894	0.85

Sequence Information

Coding Sequence: ATGCCAAATATGTCGAGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCCGAAAACATGTCGACGGCGACAGTGACGCCagcgttgcagcagcagcagcagcagcagcatcatcagcagcagcagcgtcacaATGTCTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAACATGGTGCCGGTCATAGCCAactataataatcataatcacaatcacaatcacaatcataGCGGCAGCTTGCGCATTCCCCTCGGTGGCAATGGGGATGAGTCCGATTCGGATGCGGAGCTGGCGAACATTGAGAATCTGAAGGTGCGACGACGTGCGGCAGACAAGAATGGTCCGCGTCCCATGTCCTGGGAGGGTGAGCTGAGCGAGAACGAAACGAATGGCGGCGCCGTCGGTGACGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGCGAggtgagcagcagcaccagcagcagcagcagtgccacaACGATGGCCAGCAGTCAGGTGAACGCCATGTTGCAGCCCATCAAAACCGAACTGGAGCACATAGCCGGGgagatgcaacaacagcaacagcagcagcaacaacagcaacaacaacagcagcagcaacaacagcagcaacaacagcagcagcagcaacttcaacagcaacaacttcagctgcaacaacaacaattgctgccacTGAAGCAACAGAGCTATGCACCGAACAACAAGCTAAAACTTGCGCCAACGCAAAGTGATCccatcaatttgaaatatgagcCAACGACTACGACAACATCGTCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCcatttgccactgctgcccGCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCGCCGCTGACGTCCCGCCACGCCCCCTACACGCCCTCGCTGAGCAGAAACAACAGTGATGCGTCGCACAGCAGctgctacagctacagctccGAATTCAGTCCCACCCACTCACCGATACAGGCGCGTCATGCGCCACCCGCTGGCGTTGCTGCCTTGTTTGCCGGCAATGCAAATGGCGGTGCACTGCATCATCATAGTGTGCTCTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCACAAAATCTGAGCATGGATGGTGCGGGCGGTGCATCGCTGGATGCCAGTGCCACGTTGGCTGCCTCGCCGGCGGGCATCTCGCGTCAGCAGCTAATCAATTCGCCGTGTCCGATTTGTGGGGACAAGATCAGTGGCTTCCACTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgcggcGGTCCCTGCCAGGTGAGCATCTCGACGCGCAAAAAGTGTCCCGCCTGCCGTTTCGAGAAGTGTCTGCAGAAGGGCATGAAATTGGAGGCGATACGCGAGGATCGCACCCGAGGCGGTCGCTCCACTTATCAATGCTCCTACACGCTGCCCAATTCGATGCTCAGTCCGCTGCTCAGTCCGGATCAGGCggcagccgctgcagccgccgccgccgttgtcaatcagcagcagcaacatcagcaacaccaacagcagcgacttcaacagcatcagcagcagcaacaacagcagcaacagcagcagcagcaacacggTCCACTCAATGGctttggtggtggtggtggctccAACTCGCTGCCAGCGAGTCCCAGTCTCGGCGGGGCATCCATCAAGACGGAGCAAGCGGAGCAGCTTAATCATCATACGTCATCATCAGCGCGAGCCTCAAGCATTCCAGCCCTGTTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCATTTGCAACTGGTGGCTCAGCGTCGAGCGGCACAGGCGGTTCTAGTTCCGCCGGACAGCATACGGGCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCATCCAACGGCGAGAACGCCAATCCCGATCTGATCGCACACCTCTGCAACGTGGCCGATCATCGCCTCTACAAGATCGTCAAATGGTGCAAAAGTTTGCCGCTCTTCAAGAATATCTCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGCGAACTGTTGCTCTTCTCCTGCTGTTTTCGTTCCGTCGATACGCCCGGCGAGATCAAGATGTCACAGGGCAGAAAGATAACGCTGGCACAGGCTAAAACCAATGGCTTGCAGGCGTGCATTGAGCGCATGCTGAATCTGACGGATCATTTGCGTCGCCTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACAACGGAACTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTTTGCAGGCCTACACGCTGGCCCATTATCCCGATACGCCGTCCAAGTTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGTcagCTGGGCAAGGAAATGCTGACGATCAAAACGCGCGATGGTGcagattttaatttgctgatGGAACTGCTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPENMSTATVTPALQQQQQQQHHQQQQRHNVSVTNIKCELDELATPTNGNMVPVIANYNNHNHNHNHNHSGSLRIPLGGNGDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSENETNGGAVGDEEELMETETVIKSEVSSSTSSSSSATTMASSQVNAMLQPIKTELEHIAGEMQQQQQQQQQQQQQQQQQQQQQQQQQQQLQQQQLQLQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFAGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDGAGGASLDASATLAASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQHQQHQQQRLQQHQQQQQQQQQQQQQHGPLNGFGGGGGSNSLPASPSLGGASIKTEQAEQLNHHTSSSARASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSASSGTGGSSSAGQHTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00595983;
80% Identity: iTF_00619885;